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The map label for this gene is leuE [H]

Identifier: 119946540

GI number: 119946540

Start: 3600260

End: 3600895

Strand: Reverse

Name: leuE [H]

Synonym: Ping_2918

Alternate gene names: 119946540

Gene position: 3600895-3600260 (Counterclockwise)

Preceding gene: 119946542

Following gene: 119946539

Centisome position: 78.97

GC content: 38.05

Gene sequence:

>636_bases
ATGTTTGAAAGTTTTGGTGTCATTAATATCTGGACTTATATTGCCGGTCTTATTTTTATTATTCTTGCTCCCGGACCTAA
TTCACTTTATGTGTTGAAAACCGGAGCAAGTTACGGCATAGCGACTGGCTATCGCGCTGTGGCAGGGGTGTTGTTAGGGG
ATGCAATTCTGATTTTATTGTCTTATCTTGGTGTCGCCTCGTTGGTTCAAGCGTCTCCTATTTTGTTTACTGCAATGCGT
TATTTAGGTGCGGCTTACCTTTTGTATCTTGGTGTTAGTTTAATCTACAGTAACTGGGTAGCCCCAAAAGTTAAAACATC
TTCCCCAAAAATAAAGACAGAAAAAGTTTTCCGTAAATCGCTTAGCTTGAGCTTAACCAATCCTAAAGCCTTGCTTTTTT
ATGTGTCATTTTTCATTCAATTCGTTGATTACAGTTATCACAGCACTTGGATTTCATATTCAATTTTGGCAACAATCTTA
GAGGTTTTTAGTTTAATCTATCTTAGTGTGTTAATTGTGTTGGGCAGTGCGATGACCCAGTATTTTCATCGAAATAAGTC
CTTAGCTAAACTGGGAAACAGCCTATTAGGAGTGTTTTTTATGGGCTTTGCGGCAAGATTGTCTATCCTAAATTAG

Upstream 100 bases:

>100_bases
TGGGGCTTTTAGGGTAAAGTATTACTTGTTATTTTAACATTATTGATAGCGGACGCTATTTTGTATTATTAAGCTATTCT
GCTTATTCTGAGGGATTGAT

Downstream 100 bases:

>100_bases
TATTGCCATTTTTATGAGCAGGGGCTGGCAAGTTCAGTATTGATAACTCAGCTAAAAACAAGATCGCAGTGGCCTGCATT
AAAACAGAATTTAGGTGTAT

Product: leucine export protein LeuE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MFESFGVINIWTYIAGLIFIILAPGPNSLYVLKTGASYGIATGYRAVAGVLLGDAILILLSYLGVASLVQASPILFTAMR
YLGAAYLLYLGVSLIYSNWVAPKVKTSSPKIKTEKVFRKSLSLSLTNPKALLFYVSFFIQFVDYSYHSTWISYSILATIL
EVFSLIYLSVLIVLGSAMTQYFHRNKSLAKLGNSLLGVFFMGFAARLSILN

Sequences:

>Translated_211_residues
MFESFGVINIWTYIAGLIFIILAPGPNSLYVLKTGASYGIATGYRAVAGVLLGDAILILLSYLGVASLVQASPILFTAMR
YLGAAYLLYLGVSLIYSNWVAPKVKTSSPKIKTEKVFRKSLSLSLTNPKALLFYVSFFIQFVDYSYHSTWISYSILATIL
EVFSLIYLSVLIVLGSAMTQYFHRNKSLAKLGNSLLGVFFMGFAARLSILN
>Mature_211_residues
MFESFGVINIWTYIAGLIFIILAPGPNSLYVLKTGASYGIATGYRAVAGVLLGDAILILLSYLGVASLVQASPILFTAMR
YLGAAYLLYLGVSLIYSNWVAPKVKTSSPKIKTEKVFRKSLSLSLTNPKALLFYVSFFIQFVDYSYHSTWISYSILATIL
EVFSLIYLSVLIVLGSAMTQYFHRNKSLAKLGNSLLGVFFMGFAARLSILN

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=211, Percent_Identity=51.6587677725119, Blast_Score=218, Evalue=2e-58,
Organism=Escherichia coli, GI48994979, Length=187, Percent_Identity=26.2032085561497, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23221; Mature: 23221

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFESFGVINIWTYIAGLIFIILAPGPNSLYVLKTGASYGIATGYRAVAGVLLGDAILILL
CCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
SYLGVASLVQASPILFTAMRYLGAAYLLYLGVSLIYSNWVAPKVKTSSPKIKTEKVFRKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LSLSLTNPKALLFYVSFFIQFVDYSYHSTWISYSILATILEVFSLIYLSVLIVLGSAMTQ
HCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFHRNKSLAKLGNSLLGVFFMGFAARLSILN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFESFGVINIWTYIAGLIFIILAPGPNSLYVLKTGASYGIATGYRAVAGVLLGDAILILL
CCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
SYLGVASLVQASPILFTAMRYLGAAYLLYLGVSLIYSNWVAPKVKTSSPKIKTEKVFRKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LSLSLTNPKALLFYVSFFIQFVDYSYHSTWISYSILATILEVFSLIYLSVLIVLGSAMTQ
HCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFHRNKSLAKLGNSLLGVFFMGFAARLSILN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]