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The map label for this gene is malL [H]

Identifier: 119946531

GI number: 119946531

Start: 3589223

End: 3590911

Strand: Reverse

Name: malL [H]

Synonym: Ping_2908

Alternate gene names: 119946531

Gene position: 3590911-3589223 (Counterclockwise)

Preceding gene: 119946532

Following gene: 119946530

Centisome position: 78.75

GC content: 41.86

Gene sequence:

>1689_bases
ATGAAGGGCGCAATAACAAAAAGATGGTGGCATAACTGTGTGGTCTACCAAATTTATCCACGCAGCTTTAATGACAGCAA
CGGTGATGGTCTGGGCGATATTCAGGGCATTATCAATAAACTGGATCATATTCAGGCATTGGGCGCTAATATTATCTGGT
TAAGCCCGGTAAACCAGTCACCCATGGATGATAATGGCTACGATATTTCTGATTATTATAAAATTGCGCCAGAATACGGC
ACCATGGACGACATGGAATTATTGATTGTGGAAGCTAAAAAACGCGACATTAAAATTTTAATGGATCTGGTGGTCAATCA
TACCTCCGATGAGCACCCCTGGTTTGTTGAATCTAAAAGCAGCTTAGATAATCCAAAACGGGATTGGTATATCTGGAAAG
ATCCTAAACCCGACGGCAGTGAGCCCAATAACTGGGAATCCTTTTTTACCCCGAAAGCCTGGGAATTAGATGCTGCGAGC
AAGCAATACTATTTACATTTGTTCAGTAAAAAGCAGCCCGATTTAAACTGGGCAAATCCGGAGGTACGTGCAGCAATTCA
TGACGTTTTACATTTTTGGCTAAAAAAAGGCATTGGTGGCTTTCGCATGGATGTTATCAATATGATTGGCAAACCCTCTG
ACTTTCCCGATGCGACCATTTTTGATGAAGGTGTTGCCGGTTGGGAGCATTGGGCAAATAACCTATTATGCCATCAATAC
CTGCGTGAAATTGATGAAAAAGTCTTGTCCCACTACGATGTTATGACCGTTGCAGAAACGCCTTTTACTACTACCTTAGA
CGGCCGTTATTACTCACATCCGGACAGACATGAAGTCAGTATGATTTTTCATTTTGAACACATGAGCATCGACAGAGAAG
AGCACAACGCTGTGCGCAAACCTTTTGATCTTGTTGAATATAAAGAGATCATGACACGCTGGCAGAATGATCTCTATCAG
AAGGGCTGGAACAGCTTATATTGGAGCAATCACGATCAGCCCAGAACGGTTTCCCGCTTTGGCAGCGACTGTAAAGAATA
TCGCAGTATCAGCGCGAAAATGCTAGGTACTCTTACCCATATGATGAGTGGCACACCCTATGTCTATCAAGGTGAAGAGA
TTGGCATGACCAATAAAATCTTTACCGATATCAGTCAATTTAATGATCTGATGGCAAAATTTCATTATCAAAAAATATTA
GCCAGTGGTCGCAGCGCGCAACAGGCTATCGATTTTCTTAACTACTTTTCCCGTGATCATGCCCGTTTGCCGATGCAATG
GGATAACGGTATTAATGCCGGATTTACCACCGGCACCCCCTGGCTGGCGCTTAATAATAATCAAGCCGTAGTGAATGCGC
AGGCCGAAAGAGAAGATGAAAATTCAATCTTTCATTATTATCGCAAGCTTATTGCCCTGCGAAAATCTGCGCTCTATGGT
GAGGTCATTACTTATGGTCAATATCAACTGCTTGATCAAGATGATGCTGATGTTTATGCCTATCAGCGCAGCTATAATGG
TAAAACCTTATTAATCATCTGTAACTTTACCCAGCAGAGCTTAACTCGACATTATAACGGGGAAATTAAACAGCTTATAT
TAAACAATTATCAAAATAATCCGCGAGCACTTTCATCATTAAGCCTTGCTCCTTATCAGGCACTGATCCTGGATATTTCA
GACAAATAA

Upstream 100 bases:

>100_bases
TTACCCTGCTAACTGAGTTAATTATTAATAAAAGTGCATAACCAGACAGATAATAACCAATTATTTTATCCAATGATTCA
TTAATATAAGGAACAGCAGT

Downstream 100 bases:

>100_bases
CAAACAGAAATAAAGACCAGATTTGTTAATAATTACACAGAAAAAACCATAGCGTTTTCTATCCGCGTTATGGTTTATTT
GATCAATGAATTTGCCGCAA

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MKGAITKRWWHNCVVYQIYPRSFNDSNGDGLGDIQGIINKLDHIQALGANIIWLSPVNQSPMDDNGYDISDYYKIAPEYG
TMDDMELLIVEAKKRDIKILMDLVVNHTSDEHPWFVESKSSLDNPKRDWYIWKDPKPDGSEPNNWESFFTPKAWELDAAS
KQYYLHLFSKKQPDLNWANPEVRAAIHDVLHFWLKKGIGGFRMDVINMIGKPSDFPDATIFDEGVAGWEHWANNLLCHQY
LREIDEKVLSHYDVMTVAETPFTTTLDGRYYSHPDRHEVSMIFHFEHMSIDREEHNAVRKPFDLVEYKEIMTRWQNDLYQ
KGWNSLYWSNHDQPRTVSRFGSDCKEYRSISAKMLGTLTHMMSGTPYVYQGEEIGMTNKIFTDISQFNDLMAKFHYQKIL
ASGRSAQQAIDFLNYFSRDHARLPMQWDNGINAGFTTGTPWLALNNNQAVVNAQAEREDENSIFHYYRKLIALRKSALYG
EVITYGQYQLLDQDDADVYAYQRSYNGKTLLIICNFTQQSLTRHYNGEIKQLILNNYQNNPRALSSLSLAPYQALILDIS
DK

Sequences:

>Translated_562_residues
MKGAITKRWWHNCVVYQIYPRSFNDSNGDGLGDIQGIINKLDHIQALGANIIWLSPVNQSPMDDNGYDISDYYKIAPEYG
TMDDMELLIVEAKKRDIKILMDLVVNHTSDEHPWFVESKSSLDNPKRDWYIWKDPKPDGSEPNNWESFFTPKAWELDAAS
KQYYLHLFSKKQPDLNWANPEVRAAIHDVLHFWLKKGIGGFRMDVINMIGKPSDFPDATIFDEGVAGWEHWANNLLCHQY
LREIDEKVLSHYDVMTVAETPFTTTLDGRYYSHPDRHEVSMIFHFEHMSIDREEHNAVRKPFDLVEYKEIMTRWQNDLYQ
KGWNSLYWSNHDQPRTVSRFGSDCKEYRSISAKMLGTLTHMMSGTPYVYQGEEIGMTNKIFTDISQFNDLMAKFHYQKIL
ASGRSAQQAIDFLNYFSRDHARLPMQWDNGINAGFTTGTPWLALNNNQAVVNAQAEREDENSIFHYYRKLIALRKSALYG
EVITYGQYQLLDQDDADVYAYQRSYNGKTLLIICNFTQQSLTRHYNGEIKQLILNNYQNNPRALSSLSLAPYQALILDIS
DK
>Mature_562_residues
MKGAITKRWWHNCVVYQIYPRSFNDSNGDGLGDIQGIINKLDHIQALGANIIWLSPVNQSPMDDNGYDISDYYKIAPEYG
TMDDMELLIVEAKKRDIKILMDLVVNHTSDEHPWFVESKSSLDNPKRDWYIWKDPKPDGSEPNNWESFFTPKAWELDAAS
KQYYLHLFSKKQPDLNWANPEVRAAIHDVLHFWLKKGIGGFRMDVINMIGKPSDFPDATIFDEGVAGWEHWANNLLCHQY
LREIDEKVLSHYDVMTVAETPFTTTLDGRYYSHPDRHEVSMIFHFEHMSIDREEHNAVRKPFDLVEYKEIMTRWQNDLYQ
KGWNSLYWSNHDQPRTVSRFGSDCKEYRSISAKMLGTLTHMMSGTPYVYQGEEIGMTNKIFTDISQFNDLMAKFHYQKIL
ASGRSAQQAIDFLNYFSRDHARLPMQWDNGINAGFTTGTPWLALNNNQAVVNAQAEREDENSIFHYYRKLIALRKSALYG
EVITYGQYQLLDQDDADVYAYQRSYNGKTLLIICNFTQQSLTRHYNGEIKQLILNNYQNNPRALSSLSLAPYQALILDIS
DK

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=540, Percent_Identity=28.7037037037037, Blast_Score=226, Evalue=3e-59,
Organism=Escherichia coli, GI1790687, Length=552, Percent_Identity=42.0289855072464, Blast_Score=460, Evalue=1e-130,
Organism=Escherichia coli, GI1786604, Length=190, Percent_Identity=26.8421052631579, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI32565753, Length=536, Percent_Identity=24.0671641791045, Blast_Score=119, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI25147709, Length=481, Percent_Identity=23.9085239085239, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322245, Length=576, Percent_Identity=37.1527777777778, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321726, Length=580, Percent_Identity=36.3793103448276, Blast_Score=374, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6324416, Length=580, Percent_Identity=37.2413793103448, Blast_Score=372, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6322241, Length=580, Percent_Identity=37.0689655172414, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6322021, Length=580, Percent_Identity=37.0689655172414, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321731, Length=582, Percent_Identity=38.1443298969072, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6319776, Length=582, Percent_Identity=38.1443298969072, Blast_Score=369, Evalue=1e-103,
Organism=Drosophila melanogaster, GI221330053, Length=589, Percent_Identity=33.786078098472, Blast_Score=295, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24583747, Length=569, Percent_Identity=34.622144112478, Blast_Score=279, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24583749, Length=569, Percent_Identity=34.622144112478, Blast_Score=278, Evalue=5e-75,
Organism=Drosophila melanogaster, GI24586599, Length=590, Percent_Identity=31.5254237288136, Blast_Score=274, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24583745, Length=539, Percent_Identity=34.6938775510204, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24586597, Length=592, Percent_Identity=31.4189189189189, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24586593, Length=531, Percent_Identity=32.2033898305085, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI45549022, Length=556, Percent_Identity=32.1942446043165, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24586589, Length=588, Percent_Identity=31.4625850340136, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24586587, Length=504, Percent_Identity=31.7460317460317, Blast_Score=244, Evalue=9e-65,
Organism=Drosophila melanogaster, GI24586591, Length=499, Percent_Identity=32.4649298597194, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI281360393, Length=477, Percent_Identity=29.769392033543, Blast_Score=192, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 65401; Mature: 65401

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGAITKRWWHNCVVYQIYPRSFNDSNGDGLGDIQGIINKLDHIQALGANIIWLSPVNQS
CCCCCCHHHHHCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCC
PMDDNGYDISDYYKIAPEYGTMDDMELLIVEAKKRDIKILMDLVVNHTSDEHPWFVESKS
CCCCCCCCHHHHHEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCC
SLDNPKRDWYIWKDPKPDGSEPNNWESFFTPKAWELDAASKQYYLHLFSKKQPDLNWANP
CCCCCCCCEEEECCCCCCCCCCCCCHHHCCCCCEECCCCCCEEEEEEECCCCCCCCCCCH
EVRAAIHDVLHFWLKKGIGGFRMDVINMIGKPSDFPDATIFDEGVAGWEHWANNLLCHQY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHH
LREIDEKVLSHYDVMTVAETPFTTTLDGRYYSHPDRHEVSMIFHFEHMSIDREEHNAVRK
HHHHHHHHHHHCCEEEEECCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHC
PFDLVEYKEIMTRWQNDLYQKGWNSLYWSNHDQPRTVSRFGSDCKEYRSISAKMLGTLTH
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MMSGTPYVYQGEEIGMTNKIFTDISQFNDLMAKFHYQKILASGRSAQQAIDFLNYFSRDH
HHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
ARLPMQWDNGINAGFTTGTPWLALNNNQAVVNAQAEREDENSIFHYYRKLIALRKSALYG
CCCCEEECCCCCCCCCCCCCEEEECCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHH
EVITYGQYQLLDQDDADVYAYQRSYNGKTLLIICNFTQQSLTRHYNGEIKQLILNNYQNN
HHHHCCCEEECCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHCCCCC
PRALSSLSLAPYQALILDISDK
CHHHHHCCCCCEEEEEEEECCC
>Mature Secondary Structure
MKGAITKRWWHNCVVYQIYPRSFNDSNGDGLGDIQGIINKLDHIQALGANIIWLSPVNQS
CCCCCCHHHHHCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCC
PMDDNGYDISDYYKIAPEYGTMDDMELLIVEAKKRDIKILMDLVVNHTSDEHPWFVESKS
CCCCCCCCHHHHHEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCC
SLDNPKRDWYIWKDPKPDGSEPNNWESFFTPKAWELDAASKQYYLHLFSKKQPDLNWANP
CCCCCCCCEEEECCCCCCCCCCCCCHHHCCCCCEECCCCCCEEEEEEECCCCCCCCCCCH
EVRAAIHDVLHFWLKKGIGGFRMDVINMIGKPSDFPDATIFDEGVAGWEHWANNLLCHQY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHH
LREIDEKVLSHYDVMTVAETPFTTTLDGRYYSHPDRHEVSMIFHFEHMSIDREEHNAVRK
HHHHHHHHHHHCCEEEEECCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHC
PFDLVEYKEIMTRWQNDLYQKGWNSLYWSNHDQPRTVSRFGSDCKEYRSISAKMLGTLTH
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MMSGTPYVYQGEEIGMTNKIFTDISQFNDLMAKFHYQKILASGRSAQQAIDFLNYFSRDH
HHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
ARLPMQWDNGINAGFTTGTPWLALNNNQAVVNAQAEREDENSIFHYYRKLIALRKSALYG
CCCCEEECCCCCCCCCCCCCEEEECCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHH
EVITYGQYQLLDQDDADVYAYQRSYNGKTLLIICNFTQQSLTRHYNGEIKQLILNNYQNN
HHHHCCCEEECCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHCCCCC
PRALSSLSLAPYQALILDISDK
CHHHHHCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1761534 [H]