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The map label for this gene is sixA [H]

Identifier: 119946435

GI number: 119946435

Start: 3457411

End: 3457887

Strand: Reverse

Name: sixA [H]

Synonym: Ping_2810

Alternate gene names: 119946435

Gene position: 3457887-3457411 (Counterclockwise)

Preceding gene: 119946436

Following gene: 119946434

Centisome position: 75.84

GC content: 45.49

Gene sequence:

>477_bases
TTGCATATCTATATTATGCGTCATGGGGAAGCTGAGATGCTCGCCCACTCAGATTCAGAAAGAGCATTAACTGCGCTTGG
ACGTTTAGAGTCAGAAATGATGGCTAGTTACTTGGCGAATCAAAATATATCTTTTGATGCTGTGTTGGTCAGCCCATATT
TACGTGCCCAACAAACTTGGCAGTCGGTTTGTCCTTATTTTTCTGCCGTTGCAAATGTACAAACCTTGCCGTTTTTAACC
CCGGGAGGCAGCGCTCGTAAATCGGTTAATGAAATTCTGGCTTTGCAGGCTGCAGGCGTGCAAAAACTGTTGATTGTGTC
TCATTTACCTCTGGTGGGATATATAGTGGGGGAGTTAGCCCCAGAGGCCGGTGTACCCGCTTTTTCGACTTCCGCCGTTG
GCATTGTCGAACTGGATGAAGATGGCTTCGGAAATCTTCATAGTTTAACCAGTGTTGCACAACTTTCGAATCAATAA

Upstream 100 bases:

>100_bases
CCATTATTGTTTTAAAAATATCCGGTGCAACCCCAATCACAGATAAAGTCTCTTAATAGACGATTGATGTCGAGCTTAAT
ATTTACTGGAGGGTAAGTTA

Downstream 100 bases:

>100_bases
GACCAAATCAATAAGACAATGGCTTTAATATATCCAATTAAGTGACTGCATTAATATCACTATGTTAATGTTGTTTGTGA
TCATTTTTTCCTGATTTTAG

Product: phosphohistidine phosphatase, SixA

Products: NA

Alternate protein names: RX6 [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MHIYIMRHGEAEMLAHSDSERALTALGRLESEMMASYLANQNISFDAVLVSPYLRAQQTWQSVCPYFSAVANVQTLPFLT
PGGSARKSVNEILALQAAGVQKLLIVSHLPLVGYIVGELAPEAGVPAFSTSAVGIVELDEDGFGNLHSLTSVAQLSNQ

Sequences:

>Translated_158_residues
MHIYIMRHGEAEMLAHSDSERALTALGRLESEMMASYLANQNISFDAVLVSPYLRAQQTWQSVCPYFSAVANVQTLPFLT
PGGSARKSVNEILALQAAGVQKLLIVSHLPLVGYIVGELAPEAGVPAFSTSAVGIVELDEDGFGNLHSLTSVAQLSNQ
>Mature_158_residues
MHIYIMRHGEAEMLAHSDSERALTALGRLESEMMASYLANQNISFDAVLVSPYLRAQQTWQSVCPYFSAVANVQTLPFLT
PGGSARKSVNEILALQAAGVQKLLIVSHLPLVGYIVGELAPEAGVPAFSTSAVGIVELDEDGFGNLHSLTSVAQLSNQ

Specific function: Exhibits phosphohistidine phosphatase activity towards the HPt domain of the ArcB sensor involved in the multistep His- Asp phosphorelay [H]

COG id: COG2062

COG function: function code T; Phosphohistidine phosphatase SixA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sixA phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788681, Length=147, Percent_Identity=44.8979591836735, Blast_Score=125, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR004449 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 3.1.3.- [C]

Molecular weight: Translated: 16929; Mature: 16929

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIYIMRHGEAEMLAHSDSERALTALGRLESEMMASYLANQNISFDAVLVSPYLRAQQTW
CEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHH
QSVCPYFSAVANVQTLPFLTPGGSARKSVNEILALQAAGVQKLLIVSHLPLVGYIVGELA
HHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHC
PEAGVPAFSTSAVGIVELDEDGFGNLHSLTSVAQLSNQ
CCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MHIYIMRHGEAEMLAHSDSERALTALGRLESEMMASYLANQNISFDAVLVSPYLRAQQTW
CEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHH
QSVCPYFSAVANVQTLPFLTPGGSARKSVNEILALQAAGVQKLLIVSHLPLVGYIVGELA
HHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHC
PEAGVPAFSTSAVGIVELDEDGFGNLHSLTSVAQLSNQ
CCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9489669; 9205837; 9278503 [H]