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The map label for this gene is galM [H]

Identifier: 119946146

GI number: 119946146

Start: 3062209

End: 3063276

Strand: Reverse

Name: galM [H]

Synonym: Ping_2506

Alternate gene names: 119946146

Gene position: 3063276-3062209 (Counterclockwise)

Preceding gene: 119946147

Following gene: 119946145

Centisome position: 67.18

GC content: 40.07

Gene sequence:

>1068_bases
ATGTCACAAGCAAACTTCTTATTAATCCAAAGCTCCATGACTAAAACCAATGCGATTGATGGTAAACCAGCAAAGCTTTT
ACATTTAACAAACCAACATGGCATGACCGCTACTTTCATGGATATAGGCGCAACATGGTTAAGCTGTACGTTACCAGTCA
ATAAAGAACATCGGGAAATCCTACTCCGCTCGCTGAACATGGAAGAACACATAAAACAAACGGCATATTTTGGTTCTGTC
GTTGGACGCTACGCAAATCGTATCAGTAGAGGAAAATTTTCGATCAATTCAAAACCGTATAAAATTACCATTAACGATGG
TGACAACTCTCTGCATGGTGGTGTAAACGGATTTGATAAACGTCGTTGGACCATCGAATCGTCGAGAGAAAATAGCGTCA
CCTTTTCTCTATATTCAAAAGATGGTGATCAAGGTTACCCAGCTAATTTACAAGTGAAAGTCACCTATACCTTGACCAAT
GACAATGAGCTTGTGATCGATTATTTTGCCAAGTCGGATAGCAATTGCCCTGTAAACTTAACCAATCACGCTTATTTCAA
TTTGGCTGGTGAGCAATCTAACGCGAAAAGCTTAGATCACACCCTACAGATGCACGCAGATCACTACTTGCCAACACATG
ATGACTTAATTCCTACAGGGGAATTACGAGCAGTGAAATCTACCAGTTTTGATTTCAATCAAGAGAAAAAAATTGGAGCA
GAATTTCTTTCTGAACAAGATCAAAAAATCGCGGGAGGCTATGACCATGCTTTTATTTTTAATAAGAAATTAACCAATGG
TGAAGCAACAGTTGTTACCTTAACTTCACCAGAAAAAGAGGTGAGCATGCGAGTTTCAACTACCAAGCCTGCGATCCAAT
TCTATTCAGGAAACTTTCTTGCCGAGACGCCCGGGGCATCAAAAATTTACCAAAATTATGACGGGCTAGCGTTAGAAACT
CAATACTTACCAGATGGTCCAAACCATTCTGAATGGGGAGAGAGTAGCGGTATTTTAAGTGCTGAAGCGACATATCAGCA
CCAAACTACCTATCAGTTTGAGTTCTAA

Upstream 100 bases:

>100_bases
CCCGCTAATCTATTGACTAATATTTTTAGCTGAAAATTAGCTGAGTTGTCGATCTGCATGGCAATTTTTATATTTAATTC
CAATCAACTAGAGAACTAAG

Downstream 100 bases:

>100_bases
AAACATTTAATCTAAAAGGTGATGTTGGGTTGAAGGTCATAGAATTGATCAGGCAAACATGTAATTCTGTTGAGATTGAG
ATTTTAAAAGGAGTTGTTAG

Product: aldose 1-epimerase

Products: NA

Alternate protein names: Galactose mutarotase; Type-1 mutarotase [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSQANFLLIQSSMTKTNAIDGKPAKLLHLTNQHGMTATFMDIGATWLSCTLPVNKEHREILLRSLNMEEHIKQTAYFGSV
VGRYANRISRGKFSINSKPYKITINDGDNSLHGGVNGFDKRRWTIESSRENSVTFSLYSKDGDQGYPANLQVKVTYTLTN
DNELVIDYFAKSDSNCPVNLTNHAYFNLAGEQSNAKSLDHTLQMHADHYLPTHDDLIPTGELRAVKSTSFDFNQEKKIGA
EFLSEQDQKIAGGYDHAFIFNKKLTNGEATVVTLTSPEKEVSMRVSTTKPAIQFYSGNFLAETPGASKIYQNYDGLALET
QYLPDGPNHSEWGESSGILSAEATYQHQTTYQFEF

Sequences:

>Translated_355_residues
MSQANFLLIQSSMTKTNAIDGKPAKLLHLTNQHGMTATFMDIGATWLSCTLPVNKEHREILLRSLNMEEHIKQTAYFGSV
VGRYANRISRGKFSINSKPYKITINDGDNSLHGGVNGFDKRRWTIESSRENSVTFSLYSKDGDQGYPANLQVKVTYTLTN
DNELVIDYFAKSDSNCPVNLTNHAYFNLAGEQSNAKSLDHTLQMHADHYLPTHDDLIPTGELRAVKSTSFDFNQEKKIGA
EFLSEQDQKIAGGYDHAFIFNKKLTNGEATVVTLTSPEKEVSMRVSTTKPAIQFYSGNFLAETPGASKIYQNYDGLALET
QYLPDGPNHSEWGESSGILSAEATYQHQTTYQFEF
>Mature_354_residues
SQANFLLIQSSMTKTNAIDGKPAKLLHLTNQHGMTATFMDIGATWLSCTLPVNKEHREILLRSLNMEEHIKQTAYFGSVV
GRYANRISRGKFSINSKPYKITINDGDNSLHGGVNGFDKRRWTIESSRENSVTFSLYSKDGDQGYPANLQVKVTYTLTND
NELVIDYFAKSDSNCPVNLTNHAYFNLAGEQSNAKSLDHTLQMHADHYLPTHDDLIPTGELRAVKSTSFDFNQEKKIGAE
FLSEQDQKIAGGYDHAFIFNKKLTNGEATVVTLTSPEKEVSMRVSTTKPAIQFYSGNFLAETPGASKIYQNYDGLALETQ
YLPDGPNHSEWGESSGILSAEATYQHQTTYQFEF

Specific function: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose [H]

COG id: COG2017

COG function: function code G; Galactose mutarotase and related enzymes

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldose epimerase family [H]

Homologues:

Organism=Homo sapiens, GI20270355, Length=297, Percent_Identity=39.3939393939394, Blast_Score=203, Evalue=2e-52,
Organism=Escherichia coli, GI1786971, Length=342, Percent_Identity=45.0292397660819, Blast_Score=303, Evalue=8e-84,
Organism=Caenorhabditis elegans, GI17557428, Length=330, Percent_Identity=31.2121212121212, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI115533334, Length=330, Percent_Identity=31.2121212121212, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319493, Length=335, Percent_Identity=27.4626865671642, Blast_Score=119, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6322004, Length=357, Percent_Identity=30.5322128851541, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324399, Length=354, Percent_Identity=25.9887005649718, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24659048, Length=341, Percent_Identity=34.0175953079179, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI24668278, Length=332, Percent_Identity=33.433734939759, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24583720, Length=332, Percent_Identity=31.9277108433735, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24668282, Length=337, Percent_Identity=29.080118694362, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24641876, Length=339, Percent_Identity=26.5486725663717, Blast_Score=131, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018052
- InterPro:   IPR013458
- InterPro:   IPR008183
- InterPro:   IPR015443
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.3 [H]

Molecular weight: Translated: 39701; Mature: 39569

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00545 ALDOSE_1_EPIMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQANFLLIQSSMTKTNAIDGKPAKLLHLTNQHGMTATFMDIGATWLSCTLPVNKEHREI
CCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCEEEEEECCCCCHHHHH
LLRSLNMEEHIKQTAYFGSVVGRYANRISRGKFSINSKPYKITINDGDNSLHGGVNGFDK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCCCCCCC
RRWTIESSRENSVTFSLYSKDGDQGYPANLQVKVTYTLTNDNELVIDYFAKSDSNCPVNL
EEEEEECCCCCEEEEEEEECCCCCCCCCEEEEEEEEEEECCCEEEEEEEECCCCCCCEEE
TNHAYFNLAGEQSNAKSLDHTLQMHADHYLPTHDDLIPTGELRAVKSTSFDFNQEKKIGA
CCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHH
EFLSEQDQKIAGGYDHAFIFNKKLTNGEATVVTLTSPEKEVSMRVSTTKPAIQFYSGNFL
HHHCCCCCHHCCCCCEEEEEEEEECCCCEEEEEEECCCCCEEEEEECCCCEEEEECCCEE
AETPGASKIYQNYDGLALETQYLPDGPNHSEWGESSGILSAEATYQHQTTYQFEF
EECCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECEECCCEEEEEEC
>Mature Secondary Structure 
SQANFLLIQSSMTKTNAIDGKPAKLLHLTNQHGMTATFMDIGATWLSCTLPVNKEHREI
CCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCEEEEEECCCCCHHHHH
LLRSLNMEEHIKQTAYFGSVVGRYANRISRGKFSINSKPYKITINDGDNSLHGGVNGFDK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCCCCCCC
RRWTIESSRENSVTFSLYSKDGDQGYPANLQVKVTYTLTNDNELVIDYFAKSDSNCPVNL
EEEEEECCCCCEEEEEEEECCCCCCCCCEEEEEEEEEEECCCEEEEEEEECCCCCCCEEE
TNHAYFNLAGEQSNAKSLDHTLQMHADHYLPTHDDLIPTGELRAVKSTSFDFNQEKKIGA
CCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHH
EFLSEQDQKIAGGYDHAFIFNKKLTNGEATVVTLTSPEKEVSMRVSTTKPAIQFYSGNFL
HHHCCCCCHHCCCCCEEEEEEEEECCCCEEEEEEECCCCCEEEEEECCCCEEEEECCCEE
AETPGASKIYQNYDGLALETQYLPDGPNHSEWGESSGILSAEATYQHQTTYQFEF
EECCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 1282642 [H]