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The map label for this gene is intA [H]

Identifier: 119946141

GI number: 119946141

Start: 3053581

End: 3054807

Strand: Direct

Name: intA [H]

Synonym: Ping_2496

Alternate gene names: 119946141

Gene position: 3053581-3054807 (Clockwise)

Preceding gene: 119946140

Following gene: 119946142

Centisome position: 66.97

GC content: 42.14

Gene sequence:

>1227_bases
ATGGCAAAGATAATTAAGCCTCTTTCACCTACTGACGTTTCAACAGCAGAAACTAAAGAAAGTGAATATAACCTTAGCGA
TGGGAATGGCCTTTTCTTACGTGTTAAACCGGTTGGTAGTAAATTTTGGATCTTCAATTACCAACGTCCAATTACAAAAA
AACGTGCCAATCTAACTTTAGGCAGGTATCCAGATTTACCTCTAGCTAAAGCTCGAACAAAAGCAATTGAAGCAAGGGAA
CTACTAGCTGAAGGTATCGATCCAAAAGAACACCGTGATTCAACCTTAAAAGCTAAACAAGCAGAGCTCAGTAATACCCT
GCAAGTTGTCTTTGAAGATTGGTTTACCGTTAAAAAAACCAGCATTAAAGAATTAACCGCTAAAAAACTCAAACAACGCT
TAGATAAATACCTGTTAACTTATCTTGGCAAATTTCCTATTAGTGAAATCACCGCCCCACAGACGATCAAAATCCTGCAG
CCAGTTGCGAACCAGGGCAAGCTTGAAACCGTTGCCAGACTTTGCCGCAACCTTAATGAAATAATGGTGTTTGCAGTTAA
CACTGGCATCATTGAACACAATAAACTTGCCGGTATTGGCAAAGCGTTTGCAAACGCTCAAGTCACTAACCAAGCTTCAC
TGAAGCCAGAAGAGCTACCAGAGCTATTAACTGCCCTTAACTACGCTGATATAAAGCTTATCACTCGCTGTTTGATTGAA
TGGCAATTACATACAATGACCCGCCCTTCTGAAACAGCTGGGGCTCGCTGGGATGAAATTGATAGAGAAAATAAACTTTG
GCACATCCCAGCAGAGCGAATGAAAAAAGGCAGACCGCATACAGTCCTCCTAACAACACAAACACTCGCGCTGTTAGAGA
CAATTGATGCAATTACAGGTGACAGTGAATATATTTTCCCTGCTGACAAAACCAATAAAAAACACATTAATAAAGAAACA
GCAAACAAAGCATTACAAAGAATGGGCTTTAAAGGTCGCCAGACGTCACACGGATTACGTGCCCTGGCAAGTACCACCCT
GAATGAGCAAAACGTCTTCGATGCAGACGTGATTGAGGCCGCCCTTTCACACGTTGATAAAGTGAGAAGTGCTTACAACC
GCACTGACTACCTTGAGCGCCGCCGCGTACTAATGGGCTGCTGGAGTGATCATATTGAAGCAGCATCGAAAGGATCTAAC
TCAATCACAGGATTAAAGGGAATGTGA

Upstream 100 bases:

>100_bases
TGTAGCAGTCCTATGACGTCTCTAGCTTTCTTGCAGAATCTACGGTTTAATGTAACACTCAATGTAACACGAATGATTTG
TGGTAATCTGGAGTGTTACA

Downstream 100 bases:

>100_bases
GTTATTGGTTAGCTATAAAAAAAATAATGACCATTAGCAATACAATCTTGTATTACAAAGTTAAGTCAACTTTGATTTTA
TCAAGTGGATTATGATCAAT

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MAKIIKPLSPTDVSTAETKESEYNLSDGNGLFLRVKPVGSKFWIFNYQRPITKKRANLTLGRYPDLPLAKARTKAIEARE
LLAEGIDPKEHRDSTLKAKQAELSNTLQVVFEDWFTVKKTSIKELTAKKLKQRLDKYLLTYLGKFPISEITAPQTIKILQ
PVANQGKLETVARLCRNLNEIMVFAVNTGIIEHNKLAGIGKAFANAQVTNQASLKPEELPELLTALNYADIKLITRCLIE
WQLHTMTRPSETAGARWDEIDRENKLWHIPAERMKKGRPHTVLLTTQTLALLETIDAITGDSEYIFPADKTNKKHINKET
ANKALQRMGFKGRQTSHGLRALASTTLNEQNVFDADVIEAALSHVDKVRSAYNRTDYLERRRVLMGCWSDHIEAASKGSN
SITGLKGM

Sequences:

>Translated_408_residues
MAKIIKPLSPTDVSTAETKESEYNLSDGNGLFLRVKPVGSKFWIFNYQRPITKKRANLTLGRYPDLPLAKARTKAIEARE
LLAEGIDPKEHRDSTLKAKQAELSNTLQVVFEDWFTVKKTSIKELTAKKLKQRLDKYLLTYLGKFPISEITAPQTIKILQ
PVANQGKLETVARLCRNLNEIMVFAVNTGIIEHNKLAGIGKAFANAQVTNQASLKPEELPELLTALNYADIKLITRCLIE
WQLHTMTRPSETAGARWDEIDRENKLWHIPAERMKKGRPHTVLLTTQTLALLETIDAITGDSEYIFPADKTNKKHINKET
ANKALQRMGFKGRQTSHGLRALASTTLNEQNVFDADVIEAALSHVDKVRSAYNRTDYLERRRVLMGCWSDHIEAASKGSN
SITGLKGM
>Mature_407_residues
AKIIKPLSPTDVSTAETKESEYNLSDGNGLFLRVKPVGSKFWIFNYQRPITKKRANLTLGRYPDLPLAKARTKAIEAREL
LAEGIDPKEHRDSTLKAKQAELSNTLQVVFEDWFTVKKTSIKELTAKKLKQRLDKYLLTYLGKFPISEITAPQTIKILQP
VANQGKLETVARLCRNLNEIMVFAVNTGIIEHNKLAGIGKAFANAQVTNQASLKPEELPELLTALNYADIKLITRCLIEW
QLHTMTRPSETAGARWDEIDRENKLWHIPAERMKKGRPHTVLLTTQTLALLETIDAITGDSEYIFPADKTNKKHINKETA
NKALQRMGFKGRQTSHGLRALASTTLNEQNVFDADVIEAALSHVDKVRSAYNRTDYLERRRVLMGCWSDHIEAASKGSNS
ITGLKGM

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=407, Percent_Identity=46.1916461916462, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI145693166, Length=401, Percent_Identity=33.1670822942643, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1788690, Length=390, Percent_Identity=29.7435897435897, Blast_Score=178, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 45932; Mature: 45801

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIIKPLSPTDVSTAETKESEYNLSDGNGLFLRVKPVGSKFWIFNYQRPITKKRANLTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCHHHHCCCEE
GRYPDLPLAKARTKAIEARELLAEGIDPKEHRDSTLKAKQAELSNTLQVVFEDWFTVKKT
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIKELTAKKLKQRLDKYLLTYLGKFPISEITAPQTIKILQPVANQGKLETVARLCRNLNE
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCC
IMVFAVNTGIIEHNKLAGIGKAFANAQVTNQASLKPEELPELLTALNYADIKLITRCLIE
EEEEEEECCEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHH
WQLHTMTRPSETAGARWDEIDRENKLWHIPAERMKKGRPHTVLLTTQTLALLETIDAITG
HHHHHCCCCCHHCCCCHHHCCCCCCEEECCHHHHHCCCCCEEEEEHHHHHHHHHHHHHCC
DSEYIFPADKTNKKHINKETANKALQRMGFKGRQTSHGLRALASTTLNEQNVFDADVIEA
CCCEEECCCCCCHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
ALSHVDKVRSAYNRTDYLERRRVLMGCWSDHIEAASKGSNSITGLKGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AKIIKPLSPTDVSTAETKESEYNLSDGNGLFLRVKPVGSKFWIFNYQRPITKKRANLTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCHHHHCCCEE
GRYPDLPLAKARTKAIEARELLAEGIDPKEHRDSTLKAKQAELSNTLQVVFEDWFTVKKT
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIKELTAKKLKQRLDKYLLTYLGKFPISEITAPQTIKILQPVANQGKLETVARLCRNLNE
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCC
IMVFAVNTGIIEHNKLAGIGKAFANAQVTNQASLKPEELPELLTALNYADIKLITRCLIE
EEEEEEECCEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHH
WQLHTMTRPSETAGARWDEIDRENKLWHIPAERMKKGRPHTVLLTTQTLALLETIDAITG
HHHHHCCCCCHHCCCCHHHCCCCCCEEECCHHHHHCCCCCEEEEEHHHHHHHHHHHHHCC
DSEYIFPADKTNKKHINKETANKALQRMGFKGRQTSHGLRALASTTLNEQNVFDADVIEA
CCCEEECCCCCCHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
ALSHVDKVRSAYNRTDYLERRRVLMGCWSDHIEAASKGSNSITGLKGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]