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The map label for this gene is cpg2 [H]

Identifier: 119946110

GI number: 119946110

Start: 3009591

End: 3010682

Strand: Direct

Name: cpg2 [H]

Synonym: Ping_2460

Alternate gene names: 119946110

Gene position: 3009591-3010682 (Clockwise)

Preceding gene: 119946106

Following gene: 119946112

Centisome position: 66.01

GC content: 40.11

Gene sequence:

>1092_bases
ATGGATTTTTCGGAATTAGCCAGCATTATTAATTTGAATTCATATACCAAGAATAAAAGTGGTGTCGATAAAAATGGTCT
TATTTTCCGTGGATGGCTGGAAGCGCTTGGTTATAAATGCACCGTATTTCCACGGACAGAGATTGGAGATCATCTGTTAT
TTAATGCTTCCTTCCAAAAAGGAAAAAAACGCGTTTTATTATTGGGACATTTAGACACGGTTTTTCCTCCTAATACATTT
ACGGCTTTTTCAGAAGATGATGAGTGGGTATATGGCCCTGGAGTCTGTGATATGAAAGGGGGAAACATCGTTGCCCTTGA
AGCGTTACGAGCCGTAAGCGCTGAGCATGGCGCAATCAGTAATATTGATATGTTATTGGTTAGCGACGAAGAAAGCGGCA
GTGATGACAGTAAAAAGTTAACAGCTGAATTGGCAAAAGATTATGATCTTTGCTTGGTTTTTGAAGCGGCAGGTGTTGAT
CATGAAGTGGTCATCGGCCGGAAAGGAGTGGGTACTTTTACTATTTCATTATTAGGTAAGGCGGCTCATGCAGGCAACCA
TTATATTAATGGATATAATGCTAATTTAGCCGCTGCACATATGATTATAAAACTAACCGAGTTAACTGATTTAATCAAAG
GAACGACAGTCAATGCGGGTAAATTTAGTGGAGGAATTGGCGCAAATACGATATCACCGACAGCTGAAATTATTGTCGAA
ATACGTTATACCCAAAGCCAAGAAAAAGAACGATTACTGCTTAGTATTAAAGCGATTGTTAATCAGACATTTGTTGAAGG
CGTGACAGCAACCATGACCGGGGGAATACAGCGTGATGTTATGCAGCCATCTGATAAGCAAGCACAATTATTAAAGCAGC
TGGAGAGCATACTAGGCTATCCGCTTAAAACAGAAAAACGTGGTGGCGTCAGTGATGCTAATATAGTGTCCTCTGCTGGT
GTCGCAACCCTTGATGGTTTTGGTCCTTTTGGTGATGGTGATCATACTGTTCATGAACGTGCTAAAAAAACAAGTTTTCT
TCGACGTATAGATGAAGTGACCAGGATATTACGCGCATTTAATATGAGATAA

Upstream 100 bases:

>100_bases
TAGTGCAAAAATTTAATTTTTGGTATTCGTCTTGGTTAATAATGTTGAAGTTTTCTTTTATTGAGGCAATATTAATCAAA
GAGTTAGATAGGGAAAAGCC

Downstream 100 bases:

>100_bases
TTTTCCTCTCATTAAATGCGAAAGCTCGAAGCTCGTAGGCCGCGCACCAATTACCACGGCTGCAGTGCATAGAATGCACC
CTACCGATAACTTCCTCCCA

Product: peptidase dimerisation domain-containing protein

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MDFSELASIINLNSYTKNKSGVDKNGLIFRGWLEALGYKCTVFPRTEIGDHLLFNASFQKGKKRVLLLGHLDTVFPPNTF
TAFSEDDEWVYGPGVCDMKGGNIVALEALRAVSAEHGAISNIDMLLVSDEESGSDDSKKLTAELAKDYDLCLVFEAAGVD
HEVVIGRKGVGTFTISLLGKAAHAGNHYINGYNANLAAAHMIIKLTELTDLIKGTTVNAGKFSGGIGANTISPTAEIIVE
IRYTQSQEKERLLLSIKAIVNQTFVEGVTATMTGGIQRDVMQPSDKQAQLLKQLESILGYPLKTEKRGGVSDANIVSSAG
VATLDGFGPFGDGDHTVHERAKKTSFLRRIDEVTRILRAFNMR

Sequences:

>Translated_363_residues
MDFSELASIINLNSYTKNKSGVDKNGLIFRGWLEALGYKCTVFPRTEIGDHLLFNASFQKGKKRVLLLGHLDTVFPPNTF
TAFSEDDEWVYGPGVCDMKGGNIVALEALRAVSAEHGAISNIDMLLVSDEESGSDDSKKLTAELAKDYDLCLVFEAAGVD
HEVVIGRKGVGTFTISLLGKAAHAGNHYINGYNANLAAAHMIIKLTELTDLIKGTTVNAGKFSGGIGANTISPTAEIIVE
IRYTQSQEKERLLLSIKAIVNQTFVEGVTATMTGGIQRDVMQPSDKQAQLLKQLESILGYPLKTEKRGGVSDANIVSSAG
VATLDGFGPFGDGDHTVHERAKKTSFLRRIDEVTRILRAFNMR
>Mature_363_residues
MDFSELASIINLNSYTKNKSGVDKNGLIFRGWLEALGYKCTVFPRTEIGDHLLFNASFQKGKKRVLLLGHLDTVFPPNTF
TAFSEDDEWVYGPGVCDMKGGNIVALEALRAVSAEHGAISNIDMLLVSDEESGSDDSKKLTAELAKDYDLCLVFEAAGVD
HEVVIGRKGVGTFTISLLGKAAHAGNHYINGYNANLAAAHMIIKLTELTDLIKGTTVNAGKFSGGIGANTISPTAEIIVE
IRYTQSQEKERLLLSIKAIVNQTFVEGVTATMTGGIQRDVMQPSDKQAQLLKQLESILGYPLKTEKRGGVSDANIVSSAG
VATLDGFGPFGDGDHTVHERAKKTSFLRRIDEVTRILRAFNMR

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 39343; Mature: 39343

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSELASIINLNSYTKNKSGVDKNGLIFRGWLEALGYKCTVFPRTEIGDHLLFNASFQK
CCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHCCCEEEEECCCCCCCEEEEECHHHC
GKKRVLLLGHLDTVFPPNTFTAFSEDDEWVYGPGVCDMKGGNIVALEALRAVSAEHGAIS
CCCEEEEEECCCCCCCCCCEEECCCCCCEEECCCEEECCCCCEEEHHHHHHHHHCCCCCC
NIDMLLVSDEESGSDDSKKLTAELAKDYDLCLVFEAAGVDHEVVIGRKGVGTFTISLLGK
CEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCEEEEEHHHH
AAHAGNHYINGYNANLAAAHMIIKLTELTDLIKGTTVNAGKFSGGIGANTISPTAEIIVE
HHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEE
IRYTQSQEKERLLLSIKAIVNQTFVEGVTATMTGGIQRDVMQPSDKQAQLLKQLESILGY
EEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCC
PLKTEKRGGVSDANIVSSAGVATLDGFGPFGDGDHTVHERAKKTSFLRRIDEVTRILRAF
CCCCCCCCCCCCHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NMR
CCC
>Mature Secondary Structure
MDFSELASIINLNSYTKNKSGVDKNGLIFRGWLEALGYKCTVFPRTEIGDHLLFNASFQK
CCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHCCCEEEEECCCCCCCEEEEECHHHC
GKKRVLLLGHLDTVFPPNTFTAFSEDDEWVYGPGVCDMKGGNIVALEALRAVSAEHGAIS
CCCEEEEEECCCCCCCCCCEEECCCCCCEEECCCEEECCCCCEEEHHHHHHHHHCCCCCC
NIDMLLVSDEESGSDDSKKLTAELAKDYDLCLVFEAAGVDHEVVIGRKGVGTFTISLLGK
CEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCEEEEEHHHH
AAHAGNHYINGYNANLAAAHMIIKLTELTDLIKGTTVNAGKFSGGIGANTISPTAEIIVE
HHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEE
IRYTQSQEKERLLLSIKAIVNQTFVEGVTATMTGGIQRDVMQPSDKQAQLLKQLESILGY
EEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCC
PLKTEKRGGVSDANIVSSAGVATLDGFGPFGDGDHTVHERAKKTSFLRRIDEVTRILRAF
CCCCCCCCCCCCHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NMR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]