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The map label for this gene is sdcS [H]

Identifier: 119945993

GI number: 119945993

Start: 2838369

End: 2839733

Strand: Direct

Name: sdcS [H]

Synonym: Ping_2334

Alternate gene names: 119945993

Gene position: 2838369-2839733 (Clockwise)

Preceding gene: 119945991

Following gene: 119945997

Centisome position: 62.25

GC content: 39.71

Gene sequence:

>1365_bases
ATGGGTAATATGGACAGCAATATCAGTAAGATTTTACTTGCAATAGGTTGTACGCTGCCGGTTTATTTTATCGCCGTTAT
TTGGCTTATCCCTGCTCAGGCAATCACGCTGGCATTAATCTGTTTGCTGGTTATGTTGTGGAGCAATAATGGATTGCCGC
TGGGCGTTGTTTCATTACTGCCGATCCTTCTTTTTCCTATGTTTGATTTGTTGCCCACGGACGAGGTCACCAGTAATTAC
AGCAACGCCATTATTTTTCTTTTTATTGGCGGTTTTTTACTGGCGATTGCAGTGGAAAAAACCGAGTTGCATAAAATTAT
TGCCAATAAAATATTAGCATTTTTTCCAAATACAATAACAGGTATGATTTATGCCCTCGCATTAACCGCGGGCAGTCTTA
GCGCGTTTCTATCGAATACCACCAGCTGCTTATTATTAATTCCGTTAGCCTTATTTTTATCTGAAGATGATGCCTTAAAA
AAGCGCTTCGCCTTGGCCATCTGTTACGGGGCAAGTATTGGCGGTATTATTACCCCCATCGGCACACCACCCAATTTGAT
TCTATACGGTCTGCTGGATCAGTTAAATCTACCCAGCATCCCGTTTATACAATGGATTTTACTGGTGTTACCCTTAGCAT
TGATTCTGTTTTTATTTCTTGGATGGATGCTTTCATGGGGAACAAAAAATCAACAGATAACTAAAAAACCATTACAGCAA
CAACCAAAATTAAGCACGGAGCAAAAAAAAGTAACCACGATATTAGTAACCCTGATCTTGTTACTTTTTATTAACTCACC
AATACAACCCTACTATGGAGGATTGGGCTTAAATGAAAAGGGGATTTTATTATGCGCAGGATTAATCTTATTTGTACCGC
CCATCAGTATCCTTAACTGGTCCGATAGCAAAAAAATTCCCTTTGAAATCTTATTTTTATTTGGCGCAGGTTTTTCCATT
GCCCATGTTTTTACAAGCTCAGGTTTGGCGGTTCAGTTAGCGACTTTTCTGCAAAGCTTTAGCCAATTACCGCTCCCACT
ATTGATTCTTTTAATCGCCAGCCTAGTCACATTTTCAACTGAAATCACCAGTAATACAGCGCTTATTTCTATGATTTTAC
CAGTTATTTACGCCCTTGGTCAGCAAAATGGTTTGGATACAAGATTGTTGATGATGGTCGCCACCATCTGCGCGAGTTAC
GCTTTTATGCTGCCCATAGCAACACCACCAAATGCGATCGCAATGAGCTGTGCGGCCGTTGAAGTTAAAAACATGATCCG
ATATGGTTTTCTCTTAAACCTTTTTTCCATACTGCTGGTCTTTGCTGTTGCATCTACCTATTGGGATTATTTTCTTAATT
TTTAA

Upstream 100 bases:

>100_bases
CGTCATATACAGCCATCTTAACAACGAATTTATTATTAAGATCGTCGGCCATTAAATCTGATATTGAGACTAAAATGATA
GGCAGATATTTCACTATTGG

Downstream 100 bases:

>100_bases
GCAGGTGAACATTCTGAATGGGTTATTCATTATATTGTGGAAAACGAAGGCTGTTCGCCTATTCTTGGCTCGTAGGGTGC
GCTTCGCGCACCGATAGCCG

Product: anion transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MGNMDSNISKILLAIGCTLPVYFIAVIWLIPAQAITLALICLLVMLWSNNGLPLGVVSLLPILLFPMFDLLPTDEVTSNY
SNAIIFLFIGGFLLAIAVEKTELHKIIANKILAFFPNTITGMIYALALTAGSLSAFLSNTTSCLLLIPLALFLSEDDALK
KRFALAICYGASIGGIITPIGTPPNLILYGLLDQLNLPSIPFIQWILLVLPLALILFLFLGWMLSWGTKNQQITKKPLQQ
QPKLSTEQKKVTTILVTLILLLFINSPIQPYYGGLGLNEKGILLCAGLILFVPPISILNWSDSKKIPFEILFLFGAGFSI
AHVFTSSGLAVQLATFLQSFSQLPLPLLILLIASLVTFSTEITSNTALISMILPVIYALGQQNGLDTRLLMMVATICASY
AFMLPIATPPNAIAMSCAAVEVKNMIRYGFLLNLFSILLVFAVASTYWDYFLNF

Sequences:

>Translated_454_residues
MGNMDSNISKILLAIGCTLPVYFIAVIWLIPAQAITLALICLLVMLWSNNGLPLGVVSLLPILLFPMFDLLPTDEVTSNY
SNAIIFLFIGGFLLAIAVEKTELHKIIANKILAFFPNTITGMIYALALTAGSLSAFLSNTTSCLLLIPLALFLSEDDALK
KRFALAICYGASIGGIITPIGTPPNLILYGLLDQLNLPSIPFIQWILLVLPLALILFLFLGWMLSWGTKNQQITKKPLQQ
QPKLSTEQKKVTTILVTLILLLFINSPIQPYYGGLGLNEKGILLCAGLILFVPPISILNWSDSKKIPFEILFLFGAGFSI
AHVFTSSGLAVQLATFLQSFSQLPLPLLILLIASLVTFSTEITSNTALISMILPVIYALGQQNGLDTRLLMMVATICASY
AFMLPIATPPNAIAMSCAAVEVKNMIRYGFLLNLFSILLVFAVASTYWDYFLNF
>Mature_453_residues
GNMDSNISKILLAIGCTLPVYFIAVIWLIPAQAITLALICLLVMLWSNNGLPLGVVSLLPILLFPMFDLLPTDEVTSNYS
NAIIFLFIGGFLLAIAVEKTELHKIIANKILAFFPNTITGMIYALALTAGSLSAFLSNTTSCLLLIPLALFLSEDDALKK
RFALAICYGASIGGIITPIGTPPNLILYGLLDQLNLPSIPFIQWILLVLPLALILFLFLGWMLSWGTKNQQITKKPLQQQ
PKLSTEQKKVTTILVTLILLLFINSPIQPYYGGLGLNEKGILLCAGLILFVPPISILNWSDSKKIPFEILFLFGAGFSIA
HVFTSSGLAVQLATFLQSFSQLPLPLLILLIASLVTFSTEITSNTALISMILPVIYALGQQNGLDTRLLMMVATICASYA
FMLPIATPPNAIAMSCAAVEVKNMIRYGFLLNLFSILLVFAVASTYWDYFLNF

Specific function: Mediates the transport of the dicarboxylates fumarate, malate, and succinate across the cytoplasmic membrane via a Na(+)- electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=518, Percent_Identity=27.2200772200772, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI4506979, Length=523, Percent_Identity=28.2982791586998, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI225637549, Length=572, Percent_Identity=26.048951048951, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI225637552, Length=489, Percent_Identity=27.4028629856851, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI301069349, Length=324, Percent_Identity=29.9382716049383, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI31377715, Length=347, Percent_Identity=29.3948126801153, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI58761541, Length=347, Percent_Identity=29.3948126801153, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI301069353, Length=347, Percent_Identity=29.3948126801153, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI219802232, Length=450, Percent_Identity=25.7777777777778, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI31795546, Length=348, Percent_Identity=26.7241379310345, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI301069346, Length=152, Percent_Identity=37.5, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI19923838, Length=336, Percent_Identity=26.7857142857143, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71988385, Length=452, Percent_Identity=27.6548672566372, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI32565804, Length=440, Percent_Identity=27.9545454545455, Blast_Score=151, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI71989118, Length=496, Percent_Identity=24.7983870967742, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI32564681, Length=532, Percent_Identity=24.812030075188, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17551790, Length=503, Percent_Identity=23.0616302186879, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324340, Length=412, Percent_Identity=26.2135922330097, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322263, Length=379, Percent_Identity=24.5382585751979, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362116, Length=480, Percent_Identity=24.5833333333333, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281366409, Length=480, Percent_Identity=24.375, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17737623, Length=480, Percent_Identity=24.375, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24666468, Length=480, Percent_Identity=24.375, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281362114, Length=480, Percent_Identity=24.5833333333333, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI281362112, Length=480, Percent_Identity=24.5833333333333, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI45551633, Length=480, Percent_Identity=24.375, Blast_Score=115, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 49550; Mature: 49419

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNMDSNISKILLAIGCTLPVYFIAVIWLIPAQAITLALICLLVMLWSNNGLPLGVVSLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
PILLFPMFDLLPTDEVTSNYSNAIIFLFIGGFLLAIAVEKTELHKIIANKILAFFPNTIT
HHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GMIYALALTAGSLSAFLSNTTSCLLLIPLALFLSEDDALKKRFALAICYGASIGGIITPI
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCCEECCC
GTPPNLILYGLLDQLNLPSIPFIQWILLVLPLALILFLFLGWMLSWGTKNQQITKKPLQQ
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
QPKLSTEQKKVTTILVTLILLLFINSPIQPYYGGLGLNEKGILLCAGLILFVPPISILNW
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCHHHCCC
SDSKKIPFEILFLFGAGFSIAHVFTSSGLAVQLATFLQSFSQLPLPLLILLIASLVTFST
CCCCCCCHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EITSNTALISMILPVIYALGQQNGLDTRLLMMVATICASYAFMLPIATPPNAIAMSCAAV
HHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
EVKNMIRYGFLLNLFSILLVFAVASTYWDYFLNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GNMDSNISKILLAIGCTLPVYFIAVIWLIPAQAITLALICLLVMLWSNNGLPLGVVSLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
PILLFPMFDLLPTDEVTSNYSNAIIFLFIGGFLLAIAVEKTELHKIIANKILAFFPNTIT
HHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GMIYALALTAGSLSAFLSNTTSCLLLIPLALFLSEDDALKKRFALAICYGASIGGIITPI
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCCEECCC
GTPPNLILYGLLDQLNLPSIPFIQWILLVLPLALILFLFLGWMLSWGTKNQQITKKPLQQ
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
QPKLSTEQKKVTTILVTLILLLFINSPIQPYYGGLGLNEKGILLCAGLILFVPPISILNW
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCHHHCCC
SDSKKIPFEILFLFGAGFSIAHVFTSSGLAVQLATFLQSFSQLPLPLLILLIASLVTFST
CCCCCCCHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EITSNTALISMILPVIYALGQQNGLDTRLLMMVATICASYAFMLPIATPPNAIAMSCAAV
HHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
EVKNMIRYGFLLNLFSILLVFAVASTYWDYFLNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA