Click here to switch to the map view.

The map label for this gene is adrA [H]

Identifier: 119945951

GI number: 119945951

Start: 2784653

End: 2785669

Strand: Reverse

Name: adrA [H]

Synonym: Ping_2291

Alternate gene names: 119945951

Gene position: 2785669-2784653 (Counterclockwise)

Preceding gene: 119945953

Following gene: 119945946

Centisome position: 61.09

GC content: 35.0

Gene sequence:

>1017_bases
ATGAAGAAAAATTTAACTTATGAACAATTAGAAGCAAAGGTAACCCTGCTTGAAAAAAAACTTAAGCAGTCCGACCGTTT
AATAAATACATCGGTAAAAGACTATCATTTTTTGCAAACCCTGGGCAATACTATTCCTACTCCGATCTATTTTAAAGATG
CGCAGGGCATCTATAGAAGTTGTAATGATAGCTTTGCAGATATCATCTTTGGTGTGAGCAAAGACCAGATAATGAATCAC
TCATTATTTGATTTAGCACAATATATACCTGCTGAATTAGCGCCGGGTTATTATGCTAAAGATCAGTATTTATTCGAAAA
TCCAGGTAAGCAGGTTTATCAAGCATCGGTCAATTGTGCCGATGGTTTAGTTCGGATTTATGTGTTTCACAAAGCCACTG
TACATGATAAAAAAAATAATGTGGTCGGTATTGTGGGTGTGATGCTTGATGTGACTGAGCTGGAAAATCAAAAGTTGGCG
TTACAAGAAAAAAGTCAACAATTAGAAGTGCATTCTGAAACTGATCCATTAACCGGATTACATAACAGACGAAAATTTAA
CGATATATTTGCAAATAACTTAAGTATTGCAAAACGGCAAACACGATTATTAAATTTTGCCATTATTGATGTTGATAATT
TTAAAAATTATAATGACACTTATGGTCATGTGGCGGGAGATAATGCGCTTATTCTATTGTCCCGTTTTCTGCAAAAGCGT
TTATTGCGTGCCGATGATTATATCTTTAGATTAGGGGGGGAAGAGTTCGGTTTATTATTCTACAGTGATGATGAAGTTAG
CGCCCGTGAATTTGCCAATAATATTCGACAAGGTGTAGAAAGTTTAGCAATTGACCATATTCAAAATGAAAATCATGAAT
TACTGACTATTTCGCTCGGCATAGTAACGATTAAACATAAGACTAAAAGTATATCAACGATTTATGAGCAGGCAGACAAT
TTAATGTACCGGGCTAAAAACAGTGGCAGAAATAGGATCTTAAGTCTGGTCATTTAA

Upstream 100 bases:

>100_bases
AGGTTAAAAATTAGTCAGTTTTACTCTCTCAATAACTGCCATCGCGTGTATTGCGTGTATCGTGGGTGTTGAGTATTGGG
ATTATAATTGTGAAAATGCG

Downstream 100 bases:

>100_bases
TCCTGCCCCCAGCGCATCGATTGTTATACTGGGGGTCGCAGAGTTAACGCGCGCCGGGTGTTATTTGTCAGAACACTCGG
CAAGTATTACTCATCCAAAC

Product: diguanylate cyclase with PAS/PAC sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKKNLTYEQLEAKVTLLEKKLKQSDRLINTSVKDYHFLQTLGNTIPTPIYFKDAQGIYRSCNDSFADIIFGVSKDQIMNH
SLFDLAQYIPAELAPGYYAKDQYLFENPGKQVYQASVNCADGLVRIYVFHKATVHDKKNNVVGIVGVMLDVTELENQKLA
LQEKSQQLEVHSETDPLTGLHNRRKFNDIFANNLSIAKRQTRLLNFAIIDVDNFKNYNDTYGHVAGDNALILLSRFLQKR
LLRADDYIFRLGGEEFGLLFYSDDEVSAREFANNIRQGVESLAIDHIQNENHELLTISLGIVTIKHKTKSISTIYEQADN
LMYRAKNSGRNRILSLVI

Sequences:

>Translated_338_residues
MKKNLTYEQLEAKVTLLEKKLKQSDRLINTSVKDYHFLQTLGNTIPTPIYFKDAQGIYRSCNDSFADIIFGVSKDQIMNH
SLFDLAQYIPAELAPGYYAKDQYLFENPGKQVYQASVNCADGLVRIYVFHKATVHDKKNNVVGIVGVMLDVTELENQKLA
LQEKSQQLEVHSETDPLTGLHNRRKFNDIFANNLSIAKRQTRLLNFAIIDVDNFKNYNDTYGHVAGDNALILLSRFLQKR
LLRADDYIFRLGGEEFGLLFYSDDEVSAREFANNIRQGVESLAIDHIQNENHELLTISLGIVTIKHKTKSISTIYEQADN
LMYRAKNSGRNRILSLVI
>Mature_338_residues
MKKNLTYEQLEAKVTLLEKKLKQSDRLINTSVKDYHFLQTLGNTIPTPIYFKDAQGIYRSCNDSFADIIFGVSKDQIMNH
SLFDLAQYIPAELAPGYYAKDQYLFENPGKQVYQASVNCADGLVRIYVFHKATVHDKKNNVVGIVGVMLDVTELENQKLA
LQEKSQQLEVHSETDPLTGLHNRRKFNDIFANNLSIAKRQTRLLNFAIIDVDNFKNYNDTYGHVAGDNALILLSRFLQKR
LLRADDYIFRLGGEEFGLLFYSDDEVSAREFANNIRQGVESLAIDHIQNENHELLTISLGIVTIKHKTKSISTIYEQADN
LMYRAKNSGRNRILSLVI

Specific function: Unknown

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=172, Percent_Identity=34.3023255813954, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787262, Length=162, Percent_Identity=37.037037037037, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87081881, Length=174, Percent_Identity=37.9310344827586, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788085, Length=172, Percent_Identity=32.5581395348837, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787802, Length=177, Percent_Identity=30.5084745762712, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788956, Length=181, Percent_Identity=37.0165745856354, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787816, Length=167, Percent_Identity=33.5329341317365, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788381, Length=192, Percent_Identity=33.8541666666667, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=35.625, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87081977, Length=166, Percent_Identity=31.9277108433735, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787541, Length=210, Percent_Identity=26.6666666666667, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87082007, Length=172, Percent_Identity=31.3953488372093, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87081974, Length=159, Percent_Identity=28.9308176100629, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 38632; Mature: 38632

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNLTYEQLEAKVTLLEKKLKQSDRLINTSVKDYHFLQTLGNTIPTPIYFKDAQGIYRS
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCHHHHH
CNDSFADIIFGVSKDQIMNHSLFDLAQYIPAELAPGYYAKDQYLFENPGKQVYQASVNCA
CCCCHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHCCHH
DGLVRIYVFHKATVHDKKNNVVGIVGVMLDVTELENQKLALQEKSQQLEVHSETDPLTGL
CCEEEEEEEEEEEECCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCCCC
HNRRKFNDIFANNLSIAKRQTRLLNFAIIDVDNFKNYNDTYGHVAGDNALILLSRFLQKR
CCCHHHHHHHHCCHHHHHHHHHEEEEEEEEECCCCCCCCCCCEECCCCHHHHHHHHHHHH
LLRADDYIFRLGGEEFGLLFYSDDEVSAREFANNIRQGVESLAIDHIQNENHELLTISLG
HHCCCCEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
IVTIKHKTKSISTIYEQADNLMYRAKNSGRNRILSLVI
EEEEEECHHHHHHHHHHHHHHEEECCCCCCCCEEEEEC
>Mature Secondary Structure
MKKNLTYEQLEAKVTLLEKKLKQSDRLINTSVKDYHFLQTLGNTIPTPIYFKDAQGIYRS
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCHHHHH
CNDSFADIIFGVSKDQIMNHSLFDLAQYIPAELAPGYYAKDQYLFENPGKQVYQASVNCA
CCCCHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHCCHH
DGLVRIYVFHKATVHDKKNNVVGIVGVMLDVTELENQKLALQEKSQQLEVHSETDPLTGL
CCEEEEEEEEEEEECCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCCCC
HNRRKFNDIFANNLSIAKRQTRLLNFAIIDVDNFKNYNDTYGHVAGDNALILLSRFLQKR
CCCHHHHHHHHCCHHHHHHHHHEEEEEEEEECCCCCCCCCCCEECCCCHHHHHHHHHHHH
LLRADDYIFRLGGEEFGLLFYSDDEVSAREFANNIRQGVESLAIDHIQNENHELLTISLG
HHCCCCEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
IVTIKHKTKSISTIYEQADNLMYRAKNSGRNRILSLVI
EEEEEECHHHHHHHHHHHHHHEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]