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The map label for this gene is rhbA [H]

Identifier: 119945947

GI number: 119945947

Start: 2779077

End: 2780501

Strand: Direct

Name: rhbA [H]

Synonym: Ping_2287

Alternate gene names: 119945947

Gene position: 2779077-2780501 (Clockwise)

Preceding gene: 119945939

Following gene: 119945948

Centisome position: 60.95

GC content: 42.53

Gene sequence:

>1425_bases
ATGCAAAACGTCCTGAATTTGACGCCTGAAACCCATTTATCAAACGATCAAGAAATCCCCTTAGTAAACGAATTATATGA
TTTGACACCTGACAATGTGCTTTTAAATCAAGAACATTATGAATCAGAAGTGCGCTCATACTCGCGTCGTTTACCGCTGG
CGATTAATAAAAGTCGGGGCGTTATTATTGAAGATACCAAAGGACAAGTTTATTTAGATTGTCTTGCGGGTGCAGGTGCT
TTGCCGCTTGGACACAACCATTTTGAAATCAACCAAGCGATGATAGAACAACTCAATAAAGGGGTACCTTATCAAACATT
GGATATTACGACCCCGGGCAAAGACAAATTCATAAAATCTGTGATGCAGTTTTTACCCGCTAATTTTGCTAAAAATGCCT
GTATTCAATTTTGTGGTCCCTCTGGGGCAGATGCTGTAGAAGCCTCTATTAAACTTGCAAAACTTTATACTAAACGTAAT
ACCATGATTTCTTTCCATGGTGCTTACCACGGCATGACCAATGGCGCGTTATCATTAACCGGTAATTTGGGGGCTAAAAA
ACGCCGCAGCGGATTAATGCCCGATGTACATTTTTTCCCTTTTCCATACAATTTACGTTGTACCTTTGGCCTCGGTGGCA
TGGAAGGCGTTAAACAGAGCATTCGTTATATAGAATCGGTCTTAAATGATGATGAAAGTGGCATTACTAAACCTGCTGCT
ATTATTGTTGAACCTATTCAGGGCGAAGGTGGGGTGAACCCTGCGCCGGTTTTCTGGTTACAGGAACTGCGACGTATTGC
CACTGAACAAGGTATTTTATTAATCTTTGATGAAATTCAGTGCGGTATTGGGCGCTCTGGAGACAATTTTGCTTTTGAAG
CGTCAGGTATTGAGCCTGATATCCTTATATTATCCAAAGCGATTGGCGGTGGCATGCCCATGTCAGTTATTTTGTACAAC
AAAAAATTTGATTGCTGGAACGCAGGTGAACATACCGGTACTTTCCGCGGCAACCAGTTAGCGATGGCAAGTGGCGCTAA
AACACTGGAAATTATCCAACGTGATAATCTGGCCGAGAATGCCAAACAACGCGGTGAACAGTTACGCGCGTTATTATGCG
AGATTCAAACTGAAACAGATTGTATTGCCGAAGTGCGCGGACGCGGTTTAATGTGCGGCATTGAAATAGTCAAAGCAGGT
AAATTTAACTCATTAGGCCATCCGGAAAGCGATCCTGAACGTGCATCATTAATTCAACGTGCCGCGTTAGAGCGTGGTTT
AATCATTGAAAAAGGCGGCCGAAAAGGTGCTGTGTTACGCTTTTTACCACCCCTTATTATTAGCGAAACACAAATCAACT
TTGTTGCTGAAACCGTTAAAGCTGCCATTATAGCGACACAGGATAACATCACTGATGCAGCCTAA

Upstream 100 bases:

>100_bases
AATCGCTTAACCCCCTGTACCACCCTCATTTTTCTAAACGTAAGTAGAATCACTTTAACTCCATTTTATGGAGCACTTTA
AAATATTTAAGGATCTCGTT

Downstream 100 bases:

>100_bases
TTCACCTTGGTCCAAGCACTTTATCCAAGTCGCCGGGGCCAATAACCAGGCCTTTACAGTCGCCAGCCAGCAAGCACTGG
ATAATATAAACAGTCTCTTT

Product: 2,4-diaminobutyrate 4-transaminase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MQNVLNLTPETHLSNDQEIPLVNELYDLTPDNVLLNQEHYESEVRSYSRRLPLAINKSRGVIIEDTKGQVYLDCLAGAGA
LPLGHNHFEINQAMIEQLNKGVPYQTLDITTPGKDKFIKSVMQFLPANFAKNACIQFCGPSGADAVEASIKLAKLYTKRN
TMISFHGAYHGMTNGALSLTGNLGAKKRRSGLMPDVHFFPFPYNLRCTFGLGGMEGVKQSIRYIESVLNDDESGITKPAA
IIVEPIQGEGGVNPAPVFWLQELRRIATEQGILLIFDEIQCGIGRSGDNFAFEASGIEPDILILSKAIGGGMPMSVILYN
KKFDCWNAGEHTGTFRGNQLAMASGAKTLEIIQRDNLAENAKQRGEQLRALLCEIQTETDCIAEVRGRGLMCGIEIVKAG
KFNSLGHPESDPERASLIQRAALERGLIIEKGGRKGAVLRFLPPLIISETQINFVAETVKAAIIATQDNITDAA

Sequences:

>Translated_474_residues
MQNVLNLTPETHLSNDQEIPLVNELYDLTPDNVLLNQEHYESEVRSYSRRLPLAINKSRGVIIEDTKGQVYLDCLAGAGA
LPLGHNHFEINQAMIEQLNKGVPYQTLDITTPGKDKFIKSVMQFLPANFAKNACIQFCGPSGADAVEASIKLAKLYTKRN
TMISFHGAYHGMTNGALSLTGNLGAKKRRSGLMPDVHFFPFPYNLRCTFGLGGMEGVKQSIRYIESVLNDDESGITKPAA
IIVEPIQGEGGVNPAPVFWLQELRRIATEQGILLIFDEIQCGIGRSGDNFAFEASGIEPDILILSKAIGGGMPMSVILYN
KKFDCWNAGEHTGTFRGNQLAMASGAKTLEIIQRDNLAENAKQRGEQLRALLCEIQTETDCIAEVRGRGLMCGIEIVKAG
KFNSLGHPESDPERASLIQRAALERGLIIEKGGRKGAVLRFLPPLIISETQINFVAETVKAAIIATQDNITDAA
>Mature_474_residues
MQNVLNLTPETHLSNDQEIPLVNELYDLTPDNVLLNQEHYESEVRSYSRRLPLAINKSRGVIIEDTKGQVYLDCLAGAGA
LPLGHNHFEINQAMIEQLNKGVPYQTLDITTPGKDKFIKSVMQFLPANFAKNACIQFCGPSGADAVEASIKLAKLYTKRN
TMISFHGAYHGMTNGALSLTGNLGAKKRRSGLMPDVHFFPFPYNLRCTFGLGGMEGVKQSIRYIESVLNDDESGITKPAA
IIVEPIQGEGGVNPAPVFWLQELRRIATEQGILLIFDEIQCGIGRSGDNFAFEASGIEPDILILSKAIGGGMPMSVILYN
KKFDCWNAGEHTGTFRGNQLAMASGAKTLEIIQRDNLAENAKQRGEQLRALLCEIQTETDCIAEVRGRGLMCGIEIVKAG
KFNSLGHPESDPERASLIQRAALERGLIIEKGGRKGAVLRFLPPLIISETQINFVAETVKAAIIATQDNITDAA

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=455, Percent_Identity=27.4725274725275, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI4557809, Length=451, Percent_Identity=28.159645232816, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI37574042, Length=440, Percent_Identity=24.5454545454545, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI24119277, Length=451, Percent_Identity=23.9467849223947, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI226442705, Length=440, Percent_Identity=24.3181818181818, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI226442709, Length=381, Percent_Identity=24.6719160104987, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI284507298, Length=335, Percent_Identity=30.1492537313433, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI188536080, Length=435, Percent_Identity=25.9770114942529, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI38679950, Length=435, Percent_Identity=25.9770114942529, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI38679946, Length=435, Percent_Identity=25.9770114942529, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1787560, Length=452, Percent_Identity=31.858407079646, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1789016, Length=428, Percent_Identity=31.3084112149533, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI145693181, Length=419, Percent_Identity=31.5035799522673, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1788044, Length=410, Percent_Identity=30.4878048780488, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1789759, Length=407, Percent_Identity=28.992628992629, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786991, Length=458, Percent_Identity=26.8558951965066, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786349, Length=366, Percent_Identity=29.7814207650273, Blast_Score=113, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32564660, Length=437, Percent_Identity=30.6636155606407, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI71992977, Length=430, Percent_Identity=27.2093023255814, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25144271, Length=425, Percent_Identity=27.7647058823529, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25144274, Length=223, Percent_Identity=34.0807174887892, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17541228, Length=469, Percent_Identity=24.7334754797441, Blast_Score=98, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6323470, Length=447, Percent_Identity=30.8724832214765, Blast_Score=166, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6324432, Length=436, Percent_Identity=30.9633027522936, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6324386, Length=441, Percent_Identity=23.1292517006803, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28574759, Length=438, Percent_Identity=27.6255707762557, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI161085790, Length=433, Percent_Identity=27.7136258660508, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21357415, Length=430, Percent_Identity=28.3720930232558, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI21356575, Length=465, Percent_Identity=23.8709677419355, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281366494, Length=445, Percent_Identity=24.7191011235955, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24667139, Length=445, Percent_Identity=24.7191011235955, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24667143, Length=445, Percent_Identity=24.7191011235955, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 51784; Mature: 51784

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNVLNLTPETHLSNDQEIPLVNELYDLTPDNVLLNQEHYESEVRSYSRRLPLAINKSRG
CCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEECHHHHHHHHHHHHHCCCEEEECCCC
VIIEDTKGQVYLDCLAGAGALPLGHNHFEINQAMIEQLNKGVPYQTLDITTPGKDKFIKS
EEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
VMQFLPANFAKNACIQFCGPSGADAVEASIKLAKLYTKRNTMISFHGAYHGMTNGALSLT
HHHHHCCCHHCHHHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEE
GNLGAKKRRSGLMPDVHFFPFPYNLRCTFGLGGMEGVKQSIRYIESVLNDDESGITKPAA
CCCCCHHHHCCCCCCCEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEE
IIVEPIQGEGGVNPAPVFWLQELRRIATEQGILLIFDEIQCGIGRSGDNFAFEASGIEPD
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEECCCCCC
ILILSKAIGGGMPMSVILYNKKFDCWNAGEHTGTFRGNQLAMASGAKTLEIIQRDNLAEN
EEEEEHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCEEHHHHCCHHHH
AKQRGEQLRALLCEIQTETDCIAEVRGRGLMCGIEIVKAGKFNSLGHPESDPERASLIQR
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHH
AALERGLIIEKGGRKGAVLRFLPPLIISETQINFVAETVKAAIIATQDNITDAA
HHHHCCCEEECCCCCCCHHHHCCCHHCCCCHHHHHHHHHHHEEEEECCCCCCCC
>Mature Secondary Structure
MQNVLNLTPETHLSNDQEIPLVNELYDLTPDNVLLNQEHYESEVRSYSRRLPLAINKSRG
CCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEECHHHHHHHHHHHHHCCCEEEECCCC
VIIEDTKGQVYLDCLAGAGALPLGHNHFEINQAMIEQLNKGVPYQTLDITTPGKDKFIKS
EEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
VMQFLPANFAKNACIQFCGPSGADAVEASIKLAKLYTKRNTMISFHGAYHGMTNGALSLT
HHHHHCCCHHCHHHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEE
GNLGAKKRRSGLMPDVHFFPFPYNLRCTFGLGGMEGVKQSIRYIESVLNDDESGITKPAA
CCCCCHHHHCCCCCCCEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEE
IIVEPIQGEGGVNPAPVFWLQELRRIATEQGILLIFDEIQCGIGRSGDNFAFEASGIEPD
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEECCCCCC
ILILSKAIGGGMPMSVILYNKKFDCWNAGEHTGTFRGNQLAMASGAKTLEIIQRDNLAEN
EEEEEHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCEEHHHHCCHHHH
AKQRGEQLRALLCEIQTETDCIAEVRGRGLMCGIEIVKAGKFNSLGHPESDPERASLIQR
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHH
AALERGLIIEKGGRKGAVLRFLPPLIISETQINFVAETVKAAIIATQDNITDAA
HHHHCCCEEECCCCCCCHHHHCCCHHCCCCHHHHHHHHHHHEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11274118; 11481432 [H]