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The map label for this gene is uup [H]

Identifier: 119945941

GI number: 119945941

Start: 2770376

End: 2772292

Strand: Reverse

Name: uup [H]

Synonym: Ping_2281

Alternate gene names: 119945941

Gene position: 2772292-2770376 (Counterclockwise)

Preceding gene: 119945942

Following gene: 119945940

Centisome position: 60.8

GC content: 42.1

Gene sequence:

>1917_bases
TTGGCATTATTAACGTTACACAACGCAGAGCTCGCCTTTGGTGAGCACCCATTATTAAATAAATCCAATCTGGTTATTGA
ACCTAATGAACGAGTTTGTTTGGTCGGGCGTAATGGCGCAGGTAAATCAACCCTGTTAAAAGTATTAGACGGTCGTATTC
AACTTGAAGATGGCACTTTATTGATCAATACCGATGTCAAAGTGGCACGTTTAGAACAGGATCCACCCACAGCGAATACC
CTGAGTGCTTATGATTTTGTGGCTTCCGGCATGGAAAATGCGGGTGAAATATTAAAAGCATATCATCACCAACTTCATGT
TATCGCAGAAGACTGCAGTGAAAAGCAGTTAAATAAACTGCAAAGACTGCAGGAGCAAATCGATCAGCTGGATGCCTGGC
AGTTAGACAGTAAAATCAATCAAATATTAGATCGTTTAGGAATCGACCCCGAGGCAACGCTGGATCAGTTATCCGGTGGA
TGGTTACGCAAAGTCGCTTTAGCAAAAGCATTAGTGAATGATCCAGACCTGTTGTTGCTTGATGAGCCTACCAATCACCT
CGACGTCGGTACTATCGAGTGGTTAGAAGACTTTTTATTCAGTTTTCAAGGTGCGATTATCTTTATCAGCCACGATAGGG
AATTTATTCGCCGTTTATCAACACGTATAATTGATATTGACCGTGGTAATTTAAGCTCCTGGCCGGGTGGTTACGATGAG
TATTTGATTGCTAAAGAAGAAGCATTACGCGTCGAAGAAGAGCAGAATTCTGAATTCGATCGTAAATTGGCGATTGAAGA
AAAGTGGATTCGCCAGGGTATCAAAGCCCGTCGTACACGTAATGAAGGCCGTGTTCGAGTGCTTAAATCATTACGTAATG
AACGCGCAGATCGTCAAAATGTGCAGGGCAAAGCGAAAATTAATATTGACGCCGGCACGCGCTCCGGGAAAATCATTTTC
GAAGCCGAGCATGTTGCTTACAGTTATGATGAGCTATGCATAGTACGTGATTTTTCCTGCGCTATTATGCGCGGAGATAA
AATTGCATTAGTCGGTCGAAATGGCTGCGGCAAGAGTACCCTGTTAAAATTATTACTGAACCAATTACAGCCCGATGCAG
GTGAAATCAAGTGCGGTACTAAGCTTGATGTTGCCTACTTTGACCAATACCGGGGTGAATTAAATCCTGAAAAATCGGTA
ATGGATAACCTTGCTGAAGGTAAGCAGGAAGTGGAAGTGAATGGCATTAAACGCCATGTTTTAGGTTATTTACAAGACTT
CTTGTTCCATCCGGAACGCGCTCGTACACCCGTTAAAGCGTTATCCGGTGGTGAAAAAAACCGTCTGTTACTGGCTAAAA
TATTTTTAAAACCCAGTAACTTATTAATTCTTGATGAACCTACCAATGATCTCGATGTTGAAACGCTGGAGTTATTAGAA
GAGCTGTTAGCCAATTATAAGGGCACTTTATTATTGGTGAGCCATGACCGTAGTTTTGTTGATAATACAGTGACTAATAC
CTGGTTCTTTGATGGCAATGGTAACGTAAAACAGTTCGTCGGTGGTTATAGTGACGCTATGCGCCATAAAACCCAAAGTG
AAGCACCCGCTCAGCCTGTGATTAGCGACGTTAAAGCGGCTGCTAAAAAAGACAAAGCCCCTGTAAAAGCAGCTGCCAAG
AAAAAATTATCCTATAAATTACAACTTGAACTGGATAATTCACCGCGTTTACTTGAAGAGCTGGAAGAAAAAGTAGAAAG
TTTACAGGCAACCATTAATACGCCTGAATTTTTTAACAAAGATAAAACCGAAGCGGATGCCTTCTTAGCACAACTTGCCC
AGGCCGAAGAGCAGCTTGAAACAACCTTTATGCGCTGGGAAGAGTTAGAAGAATTGCAAAATGGAGAAAACAGCTAA

Upstream 100 bases:

>100_bases
TTATTCAAAGTGACAATGGGGATACGCTTAACTGGCCATTTGATTTACAGCAGTTAAACGATTTTATTAACCTTCATATT
TAATTAAAAAGAGTATTTAA

Downstream 100 bases:

>100_bases
ATGAGATATAAACTATCCCTGACCGGAGTGGCGTTATTATTATCTGCTAACGGTTGGGCACTTCCGGCTCCGGCTGGTGC
TGCTTACTATAGTGTTGAAA

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 637

Protein sequence:

>638_residues
MALLTLHNAELAFGEHPLLNKSNLVIEPNERVCLVGRNGAGKSTLLKVLDGRIQLEDGTLLINTDVKVARLEQDPPTANT
LSAYDFVASGMENAGEILKAYHHQLHVIAEDCSEKQLNKLQRLQEQIDQLDAWQLDSKINQILDRLGIDPEATLDQLSGG
WLRKVALAKALVNDPDLLLLDEPTNHLDVGTIEWLEDFLFSFQGAIIFISHDREFIRRLSTRIIDIDRGNLSSWPGGYDE
YLIAKEEALRVEEEQNSEFDRKLAIEEKWIRQGIKARRTRNEGRVRVLKSLRNERADRQNVQGKAKINIDAGTRSGKIIF
EAEHVAYSYDELCIVRDFSCAIMRGDKIALVGRNGCGKSTLLKLLLNQLQPDAGEIKCGTKLDVAYFDQYRGELNPEKSV
MDNLAEGKQEVEVNGIKRHVLGYLQDFLFHPERARTPVKALSGGEKNRLLLAKIFLKPSNLLILDEPTNDLDVETLELLE
ELLANYKGTLLLVSHDRSFVDNTVTNTWFFDGNGNVKQFVGGYSDAMRHKTQSEAPAQPVISDVKAAAKKDKAPVKAAAK
KKLSYKLQLELDNSPRLLEELEEKVESLQATINTPEFFNKDKTEADAFLAQLAQAEEQLETTFMRWEELEELQNGENS

Sequences:

>Translated_638_residues
MALLTLHNAELAFGEHPLLNKSNLVIEPNERVCLVGRNGAGKSTLLKVLDGRIQLEDGTLLINTDVKVARLEQDPPTANT
LSAYDFVASGMENAGEILKAYHHQLHVIAEDCSEKQLNKLQRLQEQIDQLDAWQLDSKINQILDRLGIDPEATLDQLSGG
WLRKVALAKALVNDPDLLLLDEPTNHLDVGTIEWLEDFLFSFQGAIIFISHDREFIRRLSTRIIDIDRGNLSSWPGGYDE
YLIAKEEALRVEEEQNSEFDRKLAIEEKWIRQGIKARRTRNEGRVRVLKSLRNERADRQNVQGKAKINIDAGTRSGKIIF
EAEHVAYSYDELCIVRDFSCAIMRGDKIALVGRNGCGKSTLLKLLLNQLQPDAGEIKCGTKLDVAYFDQYRGELNPEKSV
MDNLAEGKQEVEVNGIKRHVLGYLQDFLFHPERARTPVKALSGGEKNRLLLAKIFLKPSNLLILDEPTNDLDVETLELLE
ELLANYKGTLLLVSHDRSFVDNTVTNTWFFDGNGNVKQFVGGYSDAMRHKTQSEAPAQPVISDVKAAAKKDKAPVKAAAK
KKLSYKLQLELDNSPRLLEELEEKVESLQATINTPEFFNKDKTEADAFLAQLAQAEEQLETTFMRWEELEELQNGENS
>Mature_637_residues
ALLTLHNAELAFGEHPLLNKSNLVIEPNERVCLVGRNGAGKSTLLKVLDGRIQLEDGTLLINTDVKVARLEQDPPTANTL
SAYDFVASGMENAGEILKAYHHQLHVIAEDCSEKQLNKLQRLQEQIDQLDAWQLDSKINQILDRLGIDPEATLDQLSGGW
LRKVALAKALVNDPDLLLLDEPTNHLDVGTIEWLEDFLFSFQGAIIFISHDREFIRRLSTRIIDIDRGNLSSWPGGYDEY
LIAKEEALRVEEEQNSEFDRKLAIEEKWIRQGIKARRTRNEGRVRVLKSLRNERADRQNVQGKAKINIDAGTRSGKIIFE
AEHVAYSYDELCIVRDFSCAIMRGDKIALVGRNGCGKSTLLKLLLNQLQPDAGEIKCGTKLDVAYFDQYRGELNPEKSVM
DNLAEGKQEVEVNGIKRHVLGYLQDFLFHPERARTPVKALSGGEKNRLLLAKIFLKPSNLLILDEPTNDLDVETLELLEE
LLANYKGTLLLVSHDRSFVDNTVTNTWFFDGNGNVKQFVGGYSDAMRHKTQSEAPAQPVISDVKAAAKKDKAPVKAAAKK
KLSYKLQLELDNSPRLLEELEEKVESLQATINTPEFFNKDKTEADAFLAQLAQAEEQLETTFMRWEELEELQNGENS

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=531, Percent_Identity=30.5084745762712, Blast_Score=220, Evalue=4e-57,
Organism=Homo sapiens, GI10947137, Length=554, Percent_Identity=28.5198555956679, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI27881506, Length=554, Percent_Identity=28.5198555956679, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI10947135, Length=541, Percent_Identity=27.3567467652495, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI69354671, Length=541, Percent_Identity=27.3567467652495, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI9961252, Length=215, Percent_Identity=28.3720930232558, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI9955963, Length=208, Percent_Identity=31.25, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI42741659, Length=215, Percent_Identity=27.4418604651163, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI4505771, Length=215, Percent_Identity=28.3720930232558, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI9961250, Length=215, Percent_Identity=28.3720930232558, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI21536378, Length=188, Percent_Identity=29.7872340425532, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1787182, Length=635, Percent_Identity=60.6299212598425, Blast_Score=758, Evalue=0.0,
Organism=Escherichia coli, GI2367384, Length=520, Percent_Identity=32.6923076923077, Blast_Score=285, Evalue=4e-78,
Organism=Escherichia coli, GI1787041, Length=537, Percent_Identity=32.5884543761639, Blast_Score=274, Evalue=1e-74,
Organism=Escherichia coli, GI1789751, Length=647, Percent_Identity=30.2936630602782, Blast_Score=265, Evalue=8e-72,
Organism=Escherichia coli, GI1788506, Length=558, Percent_Identity=24.3727598566308, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788165, Length=198, Percent_Identity=30.8080808080808, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081791, Length=203, Percent_Identity=31.0344827586207, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787164, Length=183, Percent_Identity=34.4262295081967, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789891, Length=245, Percent_Identity=30.6122448979592, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787758, Length=171, Percent_Identity=32.1637426900585, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788761, Length=231, Percent_Identity=27.7056277056277, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786872, Length=235, Percent_Identity=26.3829787234043, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788225, Length=229, Percent_Identity=26.2008733624454, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789032, Length=282, Percent_Identity=27.3049645390071, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787029, Length=258, Percent_Identity=26.3565891472868, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790190, Length=220, Percent_Identity=26.8181818181818, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787712, Length=227, Percent_Identity=28.6343612334802, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789864, Length=238, Percent_Identity=25.6302521008403, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788897, Length=214, Percent_Identity=28.0373831775701, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87081709, Length=235, Percent_Identity=23.8297872340426, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786563, Length=230, Percent_Identity=26.5217391304348, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787105, Length=228, Percent_Identity=29.8245614035088, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=540, Percent_Identity=27.5925925925926, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17555318, Length=527, Percent_Identity=27.7039848197343, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17553372, Length=524, Percent_Identity=29.9618320610687, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI193208177, Length=223, Percent_Identity=29.1479820627803, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321121, Length=556, Percent_Identity=28.5971223021583, Blast_Score=193, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6320874, Length=519, Percent_Identity=28.131021194605, Blast_Score=184, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6325030, Length=385, Percent_Identity=28.051948051948, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324314, Length=393, Percent_Identity=27.4809160305344, Blast_Score=117, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6323278, Length=382, Percent_Identity=26.1780104712042, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24666836, Length=547, Percent_Identity=30.8957952468007, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24642252, Length=552, Percent_Identity=29.5289855072464, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI18859989, Length=552, Percent_Identity=29.5289855072464, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24641342, Length=540, Percent_Identity=28.1481481481481, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI116007184, Length=215, Percent_Identity=28.3720930232558, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221500365, Length=215, Percent_Identity=28.3720930232558, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363262, Length=216, Percent_Identity=26.3888888888889, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653245, Length=216, Percent_Identity=26.3888888888889, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71937; Mature: 71805

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLTLHNAELAFGEHPLLNKSNLVIEPNERVCLVGRNGAGKSTLLKVLDGRIQLEDGTL
CEEEEEECCCEECCCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHCCEEEEECCEE
LINTDVKVARLEQDPPTANTLSAYDFVASGMENAGEILKAYHHQLHVIAEDCSEKQLNKL
EEECCCEEEEECCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLQEQIDQLDAWQLDSKINQILDRLGIDPEATLDQLSGGWLRKVALAKALVNDPDLLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCEEEE
DEPTNHLDVGTIEWLEDFLFSFQGAIIFISHDREFIRRLSTRIIDIDRGNLSSWPGGYDE
ECCCCCCCCCHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHEEEECCCCCCCCCCCCCH
YLIAKEEALRVEEEQNSEFDRKLAIEEKWIRQGIKARRTRNEGRVRVLKSLRNERADRQN
HEEEHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
VQGKAKINIDAGTRSGKIIFEAEHVAYSYDELCIVRDFSCAIMRGDKIALVGRNGCGKST
CCCEEEEEEECCCCCCEEEEEEHHHEECCCCEEEEEECCEEEECCCEEEEEECCCCCHHH
LLKLLLNQLQPDAGEIKCGTKLDVAYFDQYRGELNPEKSVMDNLAEGKQEVEVNGIKRHV
HHHHHHHHHCCCCCCEECCCEECHHHHHHHCCCCCCHHHHHHHHHCCCCEEHHHHHHHHH
LGYLQDFLFHPERARTPVKALSGGEKNRLLLAKIFLKPSNLLILDEPTNDLDVETLELLE
HHHHHHHHCCCHHHCCCHHHHCCCCCCCEEEEEEEECCCCEEEEECCCCCCCHHHHHHHH
ELLANYKGTLLLVSHDRSFVDNTVTNTWFFDGNGNVKQFVGGYSDAMRHKTQSEAPAQPV
HHHHCCCCEEEEEECCCHHHCCCCCCEEEECCCCCHHHHHCCHHHHHHHCCCCCCCCHHH
ISDVKAAAKKDKAPVKAAAKKKLSYKLQLELDNSPRLLEELEEKVESLQATINTPEFFNK
HHHHHHHHHCCCCCHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCC
DKTEADAFLAQLAQAEEQLETTFMRWEELEELQNGENS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALLTLHNAELAFGEHPLLNKSNLVIEPNERVCLVGRNGAGKSTLLKVLDGRIQLEDGTL
EEEEEECCCEECCCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHCCEEEEECCEE
LINTDVKVARLEQDPPTANTLSAYDFVASGMENAGEILKAYHHQLHVIAEDCSEKQLNKL
EEECCCEEEEECCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLQEQIDQLDAWQLDSKINQILDRLGIDPEATLDQLSGGWLRKVALAKALVNDPDLLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCEEEE
DEPTNHLDVGTIEWLEDFLFSFQGAIIFISHDREFIRRLSTRIIDIDRGNLSSWPGGYDE
ECCCCCCCCCHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHEEEECCCCCCCCCCCCCH
YLIAKEEALRVEEEQNSEFDRKLAIEEKWIRQGIKARRTRNEGRVRVLKSLRNERADRQN
HEEEHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
VQGKAKINIDAGTRSGKIIFEAEHVAYSYDELCIVRDFSCAIMRGDKIALVGRNGCGKST
CCCEEEEEEECCCCCCEEEEEEHHHEECCCCEEEEEECCEEEECCCEEEEEECCCCCHHH
LLKLLLNQLQPDAGEIKCGTKLDVAYFDQYRGELNPEKSVMDNLAEGKQEVEVNGIKRHV
HHHHHHHHHCCCCCCEECCCEECHHHHHHHCCCCCCHHHHHHHHHCCCCEEHHHHHHHHH
LGYLQDFLFHPERARTPVKALSGGEKNRLLLAKIFLKPSNLLILDEPTNDLDVETLELLE
HHHHHHHHCCCHHHCCCHHHHCCCCCCCEEEEEEEECCCCEEEEECCCCCCCHHHHHHHH
ELLANYKGTLLLVSHDRSFVDNTVTNTWFFDGNGNVKQFVGGYSDAMRHKTQSEAPAQPV
HHHHCCCCEEEEEECCCHHHCCCCCCEEEECCCCCHHHHHCCHHHHHHHCCCCCCCCHHH
ISDVKAAAKKDKAPVKAAAKKKLSYKLQLELDNSPRLLEELEEKVESLQATINTPEFFNK
HHHHHHHHHCCCCCHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCC
DKTEADAFLAQLAQAEEQLETTFMRWEELEELQNGENS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9139905; 7751275 [H]