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The map label for this gene is rhtB [H]

Identifier: 119945843

GI number: 119945843

Start: 2657197

End: 2657817

Strand: Reverse

Name: rhtB [H]

Synonym: Ping_2183

Alternate gene names: 119945843

Gene position: 2657817-2657197 (Counterclockwise)

Preceding gene: 119945844

Following gene: 119945842

Centisome position: 58.29

GC content: 41.38

Gene sequence:

>621_bases
ATGGAATATTCTGTTCTGATATTATTTGTCCCCACTTTTTTTGCAGTATCGGCGACGCCTGGATTGTGTATGACGTTGGC
AATGACCTTGGGTATGACAATAGGTGTACGTAAAAGTCTATGGATGATGGTTGGTGAATTAGTTGGGGTTGCGCTGGTGA
CCATTTCATCATTGATTGGGGTGGCAACTATTTTATTAGCCCGGCCGAATATGTTTCTGGTGCTGAAGTATTTGGGGGGG
TTGTACCTGTTTTATCTGGGTATACAGATGTGGCGTTCTCGCGGTAAAATGGCAATTCCAGAAAATTTTGTGCAACAGGA
CAGTGTTACCCGTAAGTCACTTATAACCCAAGGATTTGTGACCGCTATTGCCAATCCAAAAGGGTGGGCTTTTATGATTT
CACTATTACCCCCTTTTATTAATTCTGAGCTACCATTATATCCACAAGCGATGATTTTAGTCGCTATCATATTGTTTTTT
GAATTAGTCTGTTTATTGCTTTATGCGGCGGGTGGTCATACTTTGCGGCACCTTCTGCAGCAACGTGGTAATGTTATTTT
AATGAATAGAATTGCCGGTAGCTTAATGATGTGTGTCGGCATCTGGTTGGTATTAACTTAA

Upstream 100 bases:

>100_bases
CGCTGTTCAAAATCATTCAATAGGATTTTGTTAAGTGAGAACAAGGATAGTCTGCAAACCACGCCTCGTTACTGGCGCTT
TTTTATCTAATTGAGAGAAA

Downstream 100 bases:

>100_bases
CGGTTCAGCCTAAAAAAATGATCTACGATGTGAGGTTCTAACAATTCTACTCATTAGGTGAGCTATTTAGAGAGAGGGTG
ATAATGGATAATATTGGCTG

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MEYSVLILFVPTFFAVSATPGLCMTLAMTLGMTIGVRKSLWMMVGELVGVALVTISSLIGVATILLARPNMFLVLKYLGG
LYLFYLGIQMWRSRGKMAIPENFVQQDSVTRKSLITQGFVTAIANPKGWAFMISLLPPFINSELPLYPQAMILVAIILFF
ELVCLLLYAAGGHTLRHLLQQRGNVILMNRIAGSLMMCVGIWLVLT

Sequences:

>Translated_206_residues
MEYSVLILFVPTFFAVSATPGLCMTLAMTLGMTIGVRKSLWMMVGELVGVALVTISSLIGVATILLARPNMFLVLKYLGG
LYLFYLGIQMWRSRGKMAIPENFVQQDSVTRKSLITQGFVTAIANPKGWAFMISLLPPFINSELPLYPQAMILVAIILFF
ELVCLLLYAAGGHTLRHLLQQRGNVILMNRIAGSLMMCVGIWLVLT
>Mature_206_residues
MEYSVLILFVPTFFAVSATPGLCMTLAMTLGMTIGVRKSLWMMVGELVGVALVTISSLIGVATILLARPNMFLVLKYLGG
LYLFYLGIQMWRSRGKMAIPENFVQQDSVTRKSLITQGFVTAIANPKGWAFMISLLPPFINSELPLYPQAMILVAIILFF
ELVCLLLYAAGGHTLRHLLQQRGNVILMNRIAGSLMMCVGIWLVLT

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=184, Percent_Identity=27.1739130434783, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22764; Mature: 22764

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYSVLILFVPTFFAVSATPGLCMTLAMTLGMTIGVRKSLWMMVGELVGVALVTISSLIG
CCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VATILLARPNMFLVLKYLGGLYLFYLGIQMWRSRGKMAIPENFVQQDSVTRKSLITQGFV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
TAIANPKGWAFMISLLPPFINSELPLYPQAMILVAIILFFELVCLLLYAAGGHTLRHLLQ
HHHCCCCCHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QRGNVILMNRIAGSLMMCVGIWLVLT
HCCCEEEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEYSVLILFVPTFFAVSATPGLCMTLAMTLGMTIGVRKSLWMMVGELVGVALVTISSLIG
CCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VATILLARPNMFLVLKYLGGLYLFYLGIQMWRSRGKMAIPENFVQQDSVTRKSLITQGFV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
TAIANPKGWAFMISLLPPFINSELPLYPQAMILVAIILFFELVCLLLYAAGGHTLRHLLQ
HHHCCCCCHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QRGNVILMNRIAGSLMMCVGIWLVLT
HCCCEEEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]