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The map label for this gene is betA [H]

Identifier: 119945742

GI number: 119945742

Start: 2520901

End: 2522589

Strand: Direct

Name: betA [H]

Synonym: Ping_2072

Alternate gene names: 119945742

Gene position: 2520901-2522589 (Clockwise)

Preceding gene: 119945741

Following gene: 119945743

Centisome position: 55.29

GC content: 45.47

Gene sequence:

>1689_bases
ATGACTAAAACAGAATATGACTATATTATTGTAGGTGCCGGAAGTGCCGGTTGTGTCCTTGCAAATCGCTTGTCAGAAGA
TCCAGAAAATCAAATTCTTCTATTAGAAACCGGTGGCAGCGATAAGAGTATCTTTATTCAAATGCCGACCGCATTATCTA
TACCTATGAACAGTAAAAAATATGCCTGGCAGTTCGAAACACAAGCAGAACCGTTTTTGGATAATCGCCGCATGCATTGT
CCGCGCGGTAAAGTATTAGGGGGTTCGTCCTCTATTAACGGCATGGTCTATGTGCGCGGCCATGCGCGTGATTTTGACGA
ATGGCAGGCGTCTGGCGCTAAAGATTGGGATTATGCGCATTGTCTACCCTACTTTAAAAAAGCCGAGACCTGGTCATTTG
GCGGTAATGATTACCGTGGAGACACTGGCCCGCTTGCTGTGAATAATGGCAATAACATGAAAAACCCGTTATACCAGGCC
TTTGTGGATGCGGGTGTTGATGCCGGTTATTTAGCAACGAAAGATTACAATGCTGAGCAGCAGGAAGGTTTTGGCCCAAT
GCACATGACTGTTAAAAATGGGGTCCGTTGGTCTACGGCGAATGCCTATTTAAGACCGGCTATGAAGCGCAATAACCTGA
CGGTTGTGACTCATGCTCTGGTACACAAAGTATTGCTTGAAGGTAAAAAAGCGGTTGGTGTGCGTTATGAGGTTAAAGGT
CAATTAACGGATACGCGTTGTAATAAAGAAGTGCTGCTCTGTGCAGGCTCAATCGGTTCTCCGCATATTCTGCAACTGTC
GGGTATTGGTGAAGCCGATACTTTGGCACAAGCTGGCATCGAGCAACATCATGAGCTACCAGGTGTGGGTAAAAACTTGC
AGGATCATCTGGAGTTTTACTTTCAGTTTAAATGCTTAAAACCGATATCACTTAACGGTCAACTGGGTCCGTTAAACAAA
TTATTGATAGGTGTACGCTGGATATTAAACAAATCGGGTTTAGGCGCGACCAATCACTTTGAGTCATGTGGCTTTATTCG
CTCTAAGAATAGTTTGGAATGGCCGGATCTCCAGTATCACTTTCTACCGGCGGCCATGCGCTATGATGGCAAAGAAGCCT
TTGCAGGTCATGGTTTCCAGGTTCATGTCGGTCATAACAAACCGAAAAGCCGCGGTGCGGTGAAAATTGTATCAAAGGAC
GCCCATATTGCGCCACAAATTCAATTTAACTATTTATCACACCAGGATGATATTGAAGCCTTTCGCGCTTGTGTTCGCTT
AACCCGCGAAATCATTAATCAGCCCGGCTTAGATGAATACCGCGGCGAAGAAATTCAGCCAGGACTTGCAATCCAGAGCG
ATCAAGAAATTGATCAGTTTGTTCGCAGTTCAGTTGAAAGTGCCTATCACCCCTCCTGCTCATGCAAAATGGGTGAAGAT
GCCATGTCGGTAGTGAACTCTGATACGAAAGTCCATGGTATCGAAGCGCTTCGCGTTGTCGATTCCTCGATTTTCCCAAC
AATTCCTAACGGCAATCTGAATTCACCGACCATTATGGTGGCAGAACGTGCAGCCGATATTATTTTAGGTAAAAAACTGC
TTGCGCCAAACGTAGCTAACGTCAAGGTAGCCGATGACTGGCAGAACAGCCAACGATTACAGGACCCTAAACGAAAGGTT
AACGCTTAA

Upstream 100 bases:

>100_bases
CGGCCGCGAAAATGGCAGCGAAACACTTAAATCCTATACTCAGATCAAAGCGGTCTATATCGGTATGCAGCCACTTGACA
GCCCGTTTTAAGGAATATAT

Downstream 100 bases:

>100_bases
TTAGGTTTAAAAAATTAATAAATTAATATTAATAAGGTGTTTTTATCGATCGATCTAGATAGAGCACCGTATTTAAGTCC
GGCCGTCGAAAGAGAAGCAT

Product: choline dehydrogenase

Products: NA

Alternate protein names: CDH; CHD [H]

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MTKTEYDYIIVGAGSAGCVLANRLSEDPENQILLLETGGSDKSIFIQMPTALSIPMNSKKYAWQFETQAEPFLDNRRMHC
PRGKVLGGSSSINGMVYVRGHARDFDEWQASGAKDWDYAHCLPYFKKAETWSFGGNDYRGDTGPLAVNNGNNMKNPLYQA
FVDAGVDAGYLATKDYNAEQQEGFGPMHMTVKNGVRWSTANAYLRPAMKRNNLTVVTHALVHKVLLEGKKAVGVRYEVKG
QLTDTRCNKEVLLCAGSIGSPHILQLSGIGEADTLAQAGIEQHHELPGVGKNLQDHLEFYFQFKCLKPISLNGQLGPLNK
LLIGVRWILNKSGLGATNHFESCGFIRSKNSLEWPDLQYHFLPAAMRYDGKEAFAGHGFQVHVGHNKPKSRGAVKIVSKD
AHIAPQIQFNYLSHQDDIEAFRACVRLTREIINQPGLDEYRGEEIQPGLAIQSDQEIDQFVRSSVESAYHPSCSCKMGED
AMSVVNSDTKVHGIEALRVVDSSIFPTIPNGNLNSPTIMVAERAADIILGKKLLAPNVANVKVADDWQNSQRLQDPKRKV
NA

Sequences:

>Translated_562_residues
MTKTEYDYIIVGAGSAGCVLANRLSEDPENQILLLETGGSDKSIFIQMPTALSIPMNSKKYAWQFETQAEPFLDNRRMHC
PRGKVLGGSSSINGMVYVRGHARDFDEWQASGAKDWDYAHCLPYFKKAETWSFGGNDYRGDTGPLAVNNGNNMKNPLYQA
FVDAGVDAGYLATKDYNAEQQEGFGPMHMTVKNGVRWSTANAYLRPAMKRNNLTVVTHALVHKVLLEGKKAVGVRYEVKG
QLTDTRCNKEVLLCAGSIGSPHILQLSGIGEADTLAQAGIEQHHELPGVGKNLQDHLEFYFQFKCLKPISLNGQLGPLNK
LLIGVRWILNKSGLGATNHFESCGFIRSKNSLEWPDLQYHFLPAAMRYDGKEAFAGHGFQVHVGHNKPKSRGAVKIVSKD
AHIAPQIQFNYLSHQDDIEAFRACVRLTREIINQPGLDEYRGEEIQPGLAIQSDQEIDQFVRSSVESAYHPSCSCKMGED
AMSVVNSDTKVHGIEALRVVDSSIFPTIPNGNLNSPTIMVAERAADIILGKKLLAPNVANVKVADDWQNSQRLQDPKRKV
NA
>Mature_561_residues
TKTEYDYIIVGAGSAGCVLANRLSEDPENQILLLETGGSDKSIFIQMPTALSIPMNSKKYAWQFETQAEPFLDNRRMHCP
RGKVLGGSSSINGMVYVRGHARDFDEWQASGAKDWDYAHCLPYFKKAETWSFGGNDYRGDTGPLAVNNGNNMKNPLYQAF
VDAGVDAGYLATKDYNAEQQEGFGPMHMTVKNGVRWSTANAYLRPAMKRNNLTVVTHALVHKVLLEGKKAVGVRYEVKGQ
LTDTRCNKEVLLCAGSIGSPHILQLSGIGEADTLAQAGIEQHHELPGVGKNLQDHLEFYFQFKCLKPISLNGQLGPLNKL
LIGVRWILNKSGLGATNHFESCGFIRSKNSLEWPDLQYHFLPAAMRYDGKEAFAGHGFQVHVGHNKPKSRGAVKIVSKDA
HIAPQIQFNYLSHQDDIEAFRACVRLTREIINQPGLDEYRGEEIQPGLAIQSDQEIDQFVRSSVESAYHPSCSCKMGEDA
MSVVNSDTKVHGIEALRVVDSSIFPTIPNGNLNSPTIMVAERAADIILGKKLLAPNVANVKVADDWQNSQRLQDPKRKVN
A

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=542, Percent_Identity=51.2915129151292, Blast_Score=548, Evalue=1e-156,
Organism=Escherichia coli, GI1786503, Length=547, Percent_Identity=52.8336380255942, Blast_Score=595, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI17532301, Length=557, Percent_Identity=46.3195691202873, Blast_Score=495, Evalue=1e-140,
Organism=Drosophila melanogaster, GI24642048, Length=580, Percent_Identity=36.3793103448276, Blast_Score=322, Evalue=4e-88,
Organism=Drosophila melanogaster, GI17137792, Length=556, Percent_Identity=35.2517985611511, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI45549471, Length=570, Percent_Identity=33.3333333333333, Blast_Score=292, Evalue=4e-79,
Organism=Drosophila melanogaster, GI45551458, Length=570, Percent_Identity=33.3333333333333, Blast_Score=292, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24642055, Length=587, Percent_Identity=33.7308347529813, Blast_Score=292, Evalue=5e-79,
Organism=Drosophila melanogaster, GI24642042, Length=593, Percent_Identity=33.5581787521079, Blast_Score=281, Evalue=7e-76,
Organism=Drosophila melanogaster, GI24642039, Length=570, Percent_Identity=34.9122807017544, Blast_Score=278, Evalue=6e-75,
Organism=Drosophila melanogaster, GI24642059, Length=565, Percent_Identity=32.7433628318584, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24650267, Length=577, Percent_Identity=33.2755632582322, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI18859995, Length=569, Percent_Identity=31.8101933216169, Blast_Score=254, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24642035, Length=571, Percent_Identity=30.9982486865149, Blast_Score=251, Evalue=9e-67,
Organism=Drosophila melanogaster, GI24642051, Length=571, Percent_Identity=30.9982486865149, Blast_Score=249, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24642037, Length=569, Percent_Identity=32.3374340949033, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI18859993, Length=571, Percent_Identity=31.3485113835377, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24645930, Length=584, Percent_Identity=27.2260273972603, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24642057, Length=593, Percent_Identity=27.4873524451939, Blast_Score=143, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.1 [H]

Molecular weight: Translated: 62143; Mature: 62012

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00623 GMC_OXRED_1 ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTEYDYIIVGAGSAGCVLANRLSEDPENQILLLETGGSDKSIFIQMPTALSIPMNSKK
CCCCCCCEEEEECCCCCHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCEEECCCCCCC
YAWQFETQAEPFLDNRRMHCPRGKVLGGSSSINGMVYVRGHARDFDEWQASGAKDWDYAH
EEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCEEEEEECCCCCCHHHHCCCCCCCCHHH
CLPYFKKAETWSFGGNDYRGDTGPLAVNNGNNMKNPLYQAFVDAGVDAGYLATKDYNAEQ
HHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCCCEEEECCCCCHH
QEGFGPMHMTVKNGVRWSTANAYLRPAMKRNNLTVVTHALVHKVLLEGKKAVGVRYEVKG
HCCCCCEEEEECCCCEEECCCHHHHHHHCCCCEEEHHHHHHHHHHHCCCHHEEEEEEEEC
QLTDTRCNKEVLLCAGSIGSPHILQLSGIGEADTLAQAGIEQHHELPGVGKNLQDHLEFY
CEECCCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHEE
FQFKCLKPISLNGQLGPLNKLLIGVRWILNKSGLGATNHFESCGFIRSKNSLEWPDLQYH
EEEEEECCEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCEEE
FLPAAMRYDGKEAFAGHGFQVHVGHNKPKSRGAVKIVSKDAHIAPQIQFNYLSHQDDIEA
EECHHHHCCCCHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCEEEEEECCCCHHHHH
FRACVRLTREIINQPGLDEYRGEEIQPGLAIQSDQEIDQFVRSSVESAYHPSCSCKMGED
HHHHHHHHHHHHCCCCCHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCCHH
AMSVVNSDTKVHGIEALRVVDSSIFPTIPNGNLNSPTIMVAERAADIILGKKLLAPNVAN
HHHHHCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCHHHCCCCCE
VKVADDWQNSQRLQDPKRKVNA
EEEECCCCCCHHHCCHHHHCCC
>Mature Secondary Structure 
TKTEYDYIIVGAGSAGCVLANRLSEDPENQILLLETGGSDKSIFIQMPTALSIPMNSKK
CCCCCCEEEEECCCCCHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCEEECCCCCCC
YAWQFETQAEPFLDNRRMHCPRGKVLGGSSSINGMVYVRGHARDFDEWQASGAKDWDYAH
EEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCEEEEEECCCCCCHHHHCCCCCCCCHHH
CLPYFKKAETWSFGGNDYRGDTGPLAVNNGNNMKNPLYQAFVDAGVDAGYLATKDYNAEQ
HHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCCCEEEECCCCCHH
QEGFGPMHMTVKNGVRWSTANAYLRPAMKRNNLTVVTHALVHKVLLEGKKAVGVRYEVKG
HCCCCCEEEEECCCCEEECCCHHHHHHHCCCCEEEHHHHHHHHHHHCCCHHEEEEEEEEC
QLTDTRCNKEVLLCAGSIGSPHILQLSGIGEADTLAQAGIEQHHELPGVGKNLQDHLEFY
CEECCCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHEE
FQFKCLKPISLNGQLGPLNKLLIGVRWILNKSGLGATNHFESCGFIRSKNSLEWPDLQYH
EEEEEECCEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCEEE
FLPAAMRYDGKEAFAGHGFQVHVGHNKPKSRGAVKIVSKDAHIAPQIQFNYLSHQDDIEA
EECHHHHCCCCHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCEEEEEECCCCHHHHH
FRACVRLTREIINQPGLDEYRGEEIQPGLAIQSDQEIDQFVRSSVESAYHPSCSCKMGED
HHHHHHHHHHHHCCCCCHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCCHH
AMSVVNSDTKVHGIEALRVVDSSIFPTIPNGNLNSPTIMVAERAADIILGKKLLAPNVAN
HHHHHCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCHHHCCCCCE
VKVADDWQNSQRLQDPKRKVNA
EEEECCCCCCHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA