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The map label for this gene is aspC [H]

Identifier: 119945663

GI number: 119945663

Start: 2404275

End: 2405465

Strand: Reverse

Name: aspC [H]

Synonym: Ping_1976

Alternate gene names: 119945663

Gene position: 2405465-2404275 (Counterclockwise)

Preceding gene: 119945664

Following gene: 119945662

Centisome position: 52.76

GC content: 40.64

Gene sequence:

>1191_bases
ATGTTTGAACAAGTGAGTATGGCGCCAGCAGATCCCATTTTAGGATTAACTGATGCATTTAAAAAAGATCCACGCACTGA
AAAAATCAATTTGGGTGTTGGAATCTATAAAAATGAAAGTGGGCAAACCCCCATTTTAGCGACTGTTAAAGAAGCCGAAA
AACGCCTGTTAGCGACAGAAACAACAAAAAGTTATTTGAGCATTGAAGGTATTGCCGCTTACGGCGAAGCTGTTCAAAAA
TTGTTGTTTGGCCAGGATTCTGAGGTCATACTATCAAATCGGGCACGTACTGCACAGGCGCCAGGTGGCACCGGTGCACT
GCGTACCGCAGCTGATTTTGCTGTCAAAAAACTGGGCATAAAAAGAATATGGGTAAGTAACCCAACCTGGGCAAATCATG
GTAATGTTTTTAAAACCGCAGGGCTTCAAGTGGTCAACTATGACTATTACAACGCGGAACAAAATGATTTAGATTTTGCT
GCTATGTTGGAATCATTACAAGCGGTTGAACCTGGTGATTTAGTGCTTTTCCATGGCTGCTGCCATAATCCGACCGGTAT
CGATCCAACCTTGGAGCAATGGGAAATTTTAGCCAAATTGATTGCTGATTTAGGGGCTGTTCCATTTTTCGACTTCGCCT
ATCAGGGATTTGCAACAGGTGTGGAAGAAGATGCTCAGGGACTGCGTATCTTTGCTAAATACAATAAAGAATTATTAGTT
GCTAACTCATTTTCTAAAAACTTTGGTTTGTATAATGAACGTGTGGGTGGCATCACTTTAGTGGCTGAAGATAGCGAGAT
TGCAGATTCTGCATTTAGTCAAATTAAATCAGGTATACGTTCAAATTACTCCAATCCTCCAGCTCATGGTGCTGCTATTG
TGACTACTATTCTGAGCGATCCTGATCTTTATCAACAATGGGATAAAGAAGTTGCAGATATGCGCGATCGTATAAAAGAG
ATGCGTGAATTATTTGTAAACACATTGAAAGAAAAGGGTGTCACCAAAGATTACAGCTTTATTAGCCGTCAAAATGGTAT
GTTTTCTTTCTCCGGTTTGTCTGCTGAACAGGTCAATCGCTTAAAAGAAGAGTTTGCTATCTACATTGTAGGTTCAGGTC
GTATTTCGGTCGCCGGTATGACCAAAGATAATATGCAACCTTTATGTGATGCACTGGTTAAAGTAATCTAA

Upstream 100 bases:

>100_bases
TGATAAATTAGCGTAATCATTACGTTTTTTATTGCTTGAAAAGGCAGTAATGGTATAACTCAGTACAGGAATATAACGTC
AGTATAGGTAAGGAAGAATT

Downstream 100 bases:

>100_bases
CCTAAATTGGTCAATACTAAGAGAAGGTTGCTCAGGCAGCCTTCTCTTGTTTTTTTCCAACATATCCGGGTTTAAAAAAT
CATGAGTAGTCGAGTTATAC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MFEQVSMAPADPILGLTDAFKKDPRTEKINLGVGIYKNESGQTPILATVKEAEKRLLATETTKSYLSIEGIAAYGEAVQK
LLFGQDSEVILSNRARTAQAPGGTGALRTAADFAVKKLGIKRIWVSNPTWANHGNVFKTAGLQVVNYDYYNAEQNDLDFA
AMLESLQAVEPGDLVLFHGCCHNPTGIDPTLEQWEILAKLIADLGAVPFFDFAYQGFATGVEEDAQGLRIFAKYNKELLV
ANSFSKNFGLYNERVGGITLVAEDSEIADSAFSQIKSGIRSNYSNPPAHGAAIVTTILSDPDLYQQWDKEVADMRDRIKE
MRELFVNTLKEKGVTKDYSFISRQNGMFSFSGLSAEQVNRLKEEFAIYIVGSGRISVAGMTKDNMQPLCDALVKVI

Sequences:

>Translated_396_residues
MFEQVSMAPADPILGLTDAFKKDPRTEKINLGVGIYKNESGQTPILATVKEAEKRLLATETTKSYLSIEGIAAYGEAVQK
LLFGQDSEVILSNRARTAQAPGGTGALRTAADFAVKKLGIKRIWVSNPTWANHGNVFKTAGLQVVNYDYYNAEQNDLDFA
AMLESLQAVEPGDLVLFHGCCHNPTGIDPTLEQWEILAKLIADLGAVPFFDFAYQGFATGVEEDAQGLRIFAKYNKELLV
ANSFSKNFGLYNERVGGITLVAEDSEIADSAFSQIKSGIRSNYSNPPAHGAAIVTTILSDPDLYQQWDKEVADMRDRIKE
MRELFVNTLKEKGVTKDYSFISRQNGMFSFSGLSAEQVNRLKEEFAIYIVGSGRISVAGMTKDNMQPLCDALVKVI
>Mature_396_residues
MFEQVSMAPADPILGLTDAFKKDPRTEKINLGVGIYKNESGQTPILATVKEAEKRLLATETTKSYLSIEGIAAYGEAVQK
LLFGQDSEVILSNRARTAQAPGGTGALRTAADFAVKKLGIKRIWVSNPTWANHGNVFKTAGLQVVNYDYYNAEQNDLDFA
AMLESLQAVEPGDLVLFHGCCHNPTGIDPTLEQWEILAKLIADLGAVPFFDFAYQGFATGVEEDAQGLRIFAKYNKELLV
ANSFSKNFGLYNERVGGITLVAEDSEIADSAFSQIKSGIRSNYSNPPAHGAAIVTTILSDPDLYQQWDKEVADMRDRIKE
MRELFVNTLKEKGVTKDYSFISRQNGMFSFSGLSAEQVNRLKEEFAIYIVGSGRISVAGMTKDNMQPLCDALVKVI

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=42.9292929292929, Blast_Score=338, Evalue=4e-93,
Organism=Homo sapiens, GI4504067, Length=393, Percent_Identity=40.2035623409669, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI117414139, Length=378, Percent_Identity=26.984126984127, Blast_Score=145, Evalue=4e-35,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=63.6363636363636, Blast_Score=552, Evalue=1e-158,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=43.3249370277078, Blast_Score=354, Evalue=7e-99,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=43.7974683544304, Blast_Score=345, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI25147133, Length=395, Percent_Identity=41.0126582278481, Blast_Score=326, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI17569539, Length=395, Percent_Identity=36.2025316455696, Blast_Score=284, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI17569537, Length=380, Percent_Identity=32.3684210526316, Blast_Score=204, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI25147136, Length=211, Percent_Identity=38.3886255924171, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=31.9391634980989, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=36.9458128078818, Blast_Score=291, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6322743, Length=433, Percent_Identity=34.1801385681293, Blast_Score=246, Evalue=7e-66,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=42.4242424242424, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=42.4242424242424, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI19920542, Length=391, Percent_Identity=42.4552429667519, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24654046, Length=395, Percent_Identity=39.4936708860759, Blast_Score=303, Evalue=9e-83,
Organism=Drosophila melanogaster, GI19922362, Length=395, Percent_Identity=39.4936708860759, Blast_Score=303, Evalue=1e-82,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43499; Mature: 43499

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEQVSMAPADPILGLTDAFKKDPRTEKINLGVGIYKNESGQTPILATVKEAEKRLLATE
CCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
TTKSYLSIEGIAAYGEAVQKLLFGQDSEVILSNRARTAQAPGGTGALRTAADFAVKKLGI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCC
KRIWVSNPTWANHGNVFKTAGLQVVNYDYYNAEQNDLDFAAMLESLQAVEPGDLVLFHGC
EEEEECCCCCCCCCCEEEECCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECC
CHNPTGIDPTLEQWEILAKLIADLGAVPFFDFAYQGFATGVEEDAQGLRIFAKYNKELLV
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHEEEEEECCCEEEE
ANSFSKNFGLYNERVGGITLVAEDSEIADSAFSQIKSGIRSNYSNPPAHGAAIVTTILSD
EECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
PDLYQQWDKEVADMRDRIKEMRELFVNTLKEKGVTKDYSFISRQNGMFSFSGLSAEQVNR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEECCCCHHHHHH
LKEEFAIYIVGSGRISVAGMTKDNMQPLCDALVKVI
HHHHEEEEEEECCEEEEEECCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MFEQVSMAPADPILGLTDAFKKDPRTEKINLGVGIYKNESGQTPILATVKEAEKRLLATE
CCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
TTKSYLSIEGIAAYGEAVQKLLFGQDSEVILSNRARTAQAPGGTGALRTAADFAVKKLGI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCC
KRIWVSNPTWANHGNVFKTAGLQVVNYDYYNAEQNDLDFAAMLESLQAVEPGDLVLFHGC
EEEEECCCCCCCCCCEEEECCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECC
CHNPTGIDPTLEQWEILAKLIADLGAVPFFDFAYQGFATGVEEDAQGLRIFAKYNKELLV
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHEEEEEECCCEEEE
ANSFSKNFGLYNERVGGITLVAEDSEIADSAFSQIKSGIRSNYSNPPAHGAAIVTTILSD
EECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
PDLYQQWDKEVADMRDRIKEMRELFVNTLKEKGVTKDYSFISRQNGMFSFSGLSAEQVNR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEECCCCHHHHHH
LKEEFAIYIVGSGRISVAGMTKDNMQPLCDALVKVI
HHHHEEEEEEECCEEEEEECCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]