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The map label for this gene is dpiA [H]

Identifier: 119945559

GI number: 119945559

Start: 2265432

End: 2266124

Strand: Direct

Name: dpiA [H]

Synonym: Ping_1864

Alternate gene names: 119945559

Gene position: 2265432-2266124 (Clockwise)

Preceding gene: 119945557

Following gene: 119945570

Centisome position: 49.68

GC content: 44.01

Gene sequence:

>693_bases
ATGTTAAATGATCAAAATGTGAAAGTGTTAATCATTGAAGATGATTTGGGTATAGCCGAAATTCATCGTCGTAATTTGAT
GAAAATAGAGGGGTTTGATGCGATCGGCATTGCAACGAGTAAAAATGAGGCGGAAACATTATTAGATGTTTTAGCCCCGG
ACTTGGTCTTACTGGATCTCTATCTCCCCGATGGAAATGGACTCGATATTTTAAGGTATCTTCGCCAGCAGGAGCATGCC
TGCGATGTGATTTTAATTACAGCGGACAGAGAAGTTGAAACATTGCAGCAGGCGATGCGCGGTGGGGTGGTTGATTACCT
GCTTAAACCCGTGGTCTTTTCGCGTCTGCAGGAAGCGCTGCATAAATATTTAAAACAAAAAAACAAGCTTGGCAGCATAG
ATGATTTAGATCAGAGTATGGTTGATTCAATGATTTTTAATGCCTTCACCGGCACCACTCAGGGAGGGCATCTGCCTAAA
GGTATCGATAAAATGACGCTGGATAAAGTGCGGGTGTTGTTTGATCAACATGCACAGATAACAGCAGATAAATCGGGAGA
GCTTATTGGAGCAAGCCGCACTACGGCAAGAAGGTATCTGGAGCACCTTATTAGCGCCGGTGAATTACAGGCGGATTTAC
ACTACGGTACGGTCGGCAGACCGGAAAGGACTTATAAAAAAACACGTGGCTGA

Upstream 100 bases:

>100_bases
ATTACTCAATATAAAGGTCAATTGATTATGGAAGACCAAGACAAAAAAGGCACACGGATGACCGCTTATATACCCAAAAT
ACTGACAAAAGGACGGATAA

Downstream 100 bases:

>100_bases
GAATACCCATTAAGCGCAACGAAATAAAGTAACGCTTAATGGGGTGTAGTAGCTACTTCTGAGGTTGAAGAGCGCTTTCT
ATTTCAGTGATGCTGCTCGG

Product: response regulator receiver/unknown domain-containing protein

Products: NA

Alternate protein names: Destabilizer of plasmid inheritance [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MLNDQNVKVLIIEDDLGIAEIHRRNLMKIEGFDAIGIATSKNEAETLLDVLAPDLVLLDLYLPDGNGLDILRYLRQQEHA
CDVILITADREVETLQQAMRGGVVDYLLKPVVFSRLQEALHKYLKQKNKLGSIDDLDQSMVDSMIFNAFTGTTQGGHLPK
GIDKMTLDKVRVLFDQHAQITADKSGELIGASRTTARRYLEHLISAGELQADLHYGTVGRPERTYKKTRG

Sequences:

>Translated_230_residues
MLNDQNVKVLIIEDDLGIAEIHRRNLMKIEGFDAIGIATSKNEAETLLDVLAPDLVLLDLYLPDGNGLDILRYLRQQEHA
CDVILITADREVETLQQAMRGGVVDYLLKPVVFSRLQEALHKYLKQKNKLGSIDDLDQSMVDSMIFNAFTGTTQGGHLPK
GIDKMTLDKVRVLFDQHAQITADKSGELIGASRTTARRYLEHLISAGELQADLHYGTVGRPERTYKKTRG
>Mature_230_residues
MLNDQNVKVLIIEDDLGIAEIHRRNLMKIEGFDAIGIATSKNEAETLLDVLAPDLVLLDLYLPDGNGLDILRYLRQQEHA
CDVILITADREVETLQQAMRGGVVDYLLKPVVFSRLQEALHKYLKQKNKLGSIDDLDQSMVDSMIFNAFTGTTQGGHLPK
GIDKMTLDKVRVLFDQHAQITADKSGELIGASRTTARRYLEHLISAGELQADLHYGTVGRPERTYKKTRG

Specific function: Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox c

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=220, Percent_Identity=40.4545454545455, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1790566, Length=224, Percent_Identity=34.375, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1788550, Length=189, Percent_Identity=28.042328042328, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25741; Mature: 25741

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNDQNVKVLIIEDDLGIAEIHRRNLMKIEGFDAIGIATSKNEAETLLDVLAPDLVLLDL
CCCCCCEEEEEEECCCCHHHHHHCCCEEECCCCEEEEECCCHHHHHHHHHHCCCEEEEEE
YLPDGNGLDILRYLRQQEHACDVILITADREVETLQQAMRGGVVDYLLKPVVFSRLQEAL
ECCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
HKYLKQKNKLGSIDDLDQSMVDSMIFNAFTGTTQGGHLPKGIDKMTLDKVRVLFDQHAQI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
TADKSGELIGASRTTARRYLEHLISAGELQADLHYGTVGRPERTYKKTRG
ECCCCCCEECCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MLNDQNVKVLIIEDDLGIAEIHRRNLMKIEGFDAIGIATSKNEAETLLDVLAPDLVLLDL
CCCCCCEEEEEEECCCCHHHHHHCCCEEECCCCEEEEECCCHHHHHHHHHHCCCEEEEEE
YLPDGNGLDILRYLRQQEHACDVILITADREVETLQQAMRGGVVDYLLKPVVFSRLQEAL
ECCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
HKYLKQKNKLGSIDDLDQSMVDSMIFNAFTGTTQGGHLPKGIDKMTLDKVRVLFDQHAQI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
TADKSGELIGASRTTARRYLEHLISAGELQADLHYGTVGRPERTYKKTRG
ECCCCCCEECCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]