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The map label for this gene is yciR [C]

Identifier: 119945537

GI number: 119945537

Start: 2237056

End: 2238852

Strand: Direct

Name: yciR [C]

Synonym: Ping_1841

Alternate gene names: 119945537

Gene position: 2237056-2238852 (Clockwise)

Preceding gene: 119945534

Following gene: 119945541

Centisome position: 49.06

GC content: 45.08

Gene sequence:

>1797_bases
ATGAGTAAGGACGTAGAATACGACAGTAAACTTAATGATAGAAAACGCCATCAGGCAGACCTTACTCTTTCCAACAATGC
GCTTGCCATTGCCAACAAGGATCTTGCCTTTCAAAATGAAGAGAAGGATAAACGGGCAGCAGAGCTTGCCATTGCCAACG
AAGAAAAAAGTAAACGGGCAGCAGAGCTTGCCATTGCTAACAAAGAGCTTGCCTTTCAAAATAAAGAGAAGGATAAACGG
GCAGCAGAGCTTGCCATTGCTAACAAAGAGCTTGCCTTTCAAAATAAAGAGAAGGATAAACGGGCAGCAGAGCTTGCCTT
TCAAAATAAAGAGAAGGATAAACGGGCAGCAGAGCTTGCCATTGCTAACAAAGAGCTTGCCTTTCAAAATAAAGAGAAAG
ATAAACGGGCAGCAGAGCTGGCCATTGCCAACAAGGAGCTTGCCATTGCCAACGAAGAGAAAGGCAAACTGACAGAAAAA
CTCAATGACCTCGCCTTCTATGACACGCTTACCGGCTTGCCCAACAGACGTATTTTGATAGACAGGCTACATCACGCGTT
AGCTTCCAATGTGCGTGAAGGCTGTGATAGTGCGGTGATGTTTGTTGATTTGGATCATTTCAAGGATATCAACGATACCC
TCGGCCATGGATTCGGTGATTTACTGCTGATCCAGATAGCGCAGCGTCTGGCGTCTTGCCTACGCAAAGGTGATACGGTG
GCGCGTCTGGGAGGGGACGAGTTTGTGTTGATTCTGGAAAATCTGGACAAAAAAACCATTGAAGCCGCAGCAAAGGCGAA
TGCCATTGCCGATAAAATTTTGGCTGCGCTTAATAAGCCCTACCAGCTTGACATGCACAAATGCTACAGCACTGTCAGTA
TCGGAGCTGTCTTTTTTGACCATCAGGGTAATACGGCAGAAGATCTGCTGAAACAAGCCGACATTGCTATGTATCAGGCC
AAACAAGCCGGCGGCAATCAGATCAGGTTCTTTAACCCGGAAATGCAGGAAATTATTAATGTGCGCATCACCCTCGAAAA
TGAACTGCGCCTTGCCATTGAAAAATCGCAATTTCATTTGTATTACCAAATTCAGATGGACAGTGCCAACCGAGTATTGG
GAGCCGAGGCATTGATCCGCTGGATGCACCCTGAACGTGGACTAGTGTTACCTGCTACCTTTATTCCTTTAGCGGAAGAA
ACCGGCTTAATTCTACCTATTGGGAAATGGGTTATCGAGACGGCTTGTGCGCAGATAAAAGTATGGCAGAAAGAGCCCCT
GACCCGCAACTTAACACTGTCAGTCAATGTGAGTGCCAAACAATTCCGGCAGAAGAATTTTGTGGAAAAAGTGCAGTCAG
CTGTAGAGCGATATGCTGTTCCCGGAAATTTACTTAAGCTGGAATTGACCGAAAGCCTGTTGCAATACGATATCGAAGTC
ACCATTGCCATGATGAAGGCATTAAATAAGATTGGTGTTCAGTTTTCCCTGGATGACTTCGGCACAGGTTATTCATCCTT
ACAATACCTTAAGCGGCTGCCCCTCGATCAGTTCAAGATAGACCAATCGTTCGTGCGTGATATTGCGACAGATAATAACG
ATAAAGCGATAGTAAAAGCGATTGTTGCTATGGCACAGATTCTGGATATAGACGTTATTGCCGAGGGAGTGGAAACTGAA
GAGCAACGACAATTACTCTTAGGCAAAGGATGCGTCTTTTTCCAAGGGTATTTATTCAGCAAACCAATACCAATTGATGA
ATTTGAGGCGTTAATTTGTCGTTTAACTGACACCTGA

Upstream 100 bases:

>100_bases
TTACTGGTATGAGAGTTGGTGTAGAGGGTGTGAATTTTTAAATATCCTGTTCCTTTGAGGCTCTCCCAACACACTGTTTA
AATGTAAGAGGGTTAAATAA

Downstream 100 bases:

>100_bases
TTTTAAACAGTGACCGCCATGCGAAAGCGCAAATTTACAGAATTTATTGAGCATGTAGGACGTAACCTAATTACCCCCAC
TTGACAGAAAAGCTATCTGT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MSKDVEYDSKLNDRKRHQADLTLSNNALAIANKDLAFQNEEKDKRAAELAIANEEKSKRAAELAIANKELAFQNKEKDKR
AAELAIANKELAFQNKEKDKRAAELAFQNKEKDKRAAELAIANKELAFQNKEKDKRAAELAIANKELAIANEEKGKLTEK
LNDLAFYDTLTGLPNRRILIDRLHHALASNVREGCDSAVMFVDLDHFKDINDTLGHGFGDLLLIQIAQRLASCLRKGDTV
ARLGGDEFVLILENLDKKTIEAAAKANAIADKILAALNKPYQLDMHKCYSTVSIGAVFFDHQGNTAEDLLKQADIAMYQA
KQAGGNQIRFFNPEMQEIINVRITLENELRLAIEKSQFHLYYQIQMDSANRVLGAEALIRWMHPERGLVLPATFIPLAEE
TGLILPIGKWVIETACAQIKVWQKEPLTRNLTLSVNVSAKQFRQKNFVEKVQSAVERYAVPGNLLKLELTESLLQYDIEV
TIAMMKALNKIGVQFSLDDFGTGYSSLQYLKRLPLDQFKIDQSFVRDIATDNNDKAIVKAIVAMAQILDIDVIAEGVETE
EQRQLLLGKGCVFFQGYLFSKPIPIDEFEALICRLTDT

Sequences:

>Translated_598_residues
MSKDVEYDSKLNDRKRHQADLTLSNNALAIANKDLAFQNEEKDKRAAELAIANEEKSKRAAELAIANKELAFQNKEKDKR
AAELAIANKELAFQNKEKDKRAAELAFQNKEKDKRAAELAIANKELAFQNKEKDKRAAELAIANKELAIANEEKGKLTEK
LNDLAFYDTLTGLPNRRILIDRLHHALASNVREGCDSAVMFVDLDHFKDINDTLGHGFGDLLLIQIAQRLASCLRKGDTV
ARLGGDEFVLILENLDKKTIEAAAKANAIADKILAALNKPYQLDMHKCYSTVSIGAVFFDHQGNTAEDLLKQADIAMYQA
KQAGGNQIRFFNPEMQEIINVRITLENELRLAIEKSQFHLYYQIQMDSANRVLGAEALIRWMHPERGLVLPATFIPLAEE
TGLILPIGKWVIETACAQIKVWQKEPLTRNLTLSVNVSAKQFRQKNFVEKVQSAVERYAVPGNLLKLELTESLLQYDIEV
TIAMMKALNKIGVQFSLDDFGTGYSSLQYLKRLPLDQFKIDQSFVRDIATDNNDKAIVKAIVAMAQILDIDVIAEGVETE
EQRQLLLGKGCVFFQGYLFSKPIPIDEFEALICRLTDT
>Mature_597_residues
SKDVEYDSKLNDRKRHQADLTLSNNALAIANKDLAFQNEEKDKRAAELAIANEEKSKRAAELAIANKELAFQNKEKDKRA
AELAIANKELAFQNKEKDKRAAELAFQNKEKDKRAAELAIANKELAFQNKEKDKRAAELAIANKELAIANEEKGKLTEKL
NDLAFYDTLTGLPNRRILIDRLHHALASNVREGCDSAVMFVDLDHFKDINDTLGHGFGDLLLIQIAQRLASCLRKGDTVA
RLGGDEFVLILENLDKKTIEAAAKANAIADKILAALNKPYQLDMHKCYSTVSIGAVFFDHQGNTAEDLLKQADIAMYQAK
QAGGNQIRFFNPEMQEIINVRITLENELRLAIEKSQFHLYYQIQMDSANRVLGAEALIRWMHPERGLVLPATFIPLAEET
GLILPIGKWVIETACAQIKVWQKEPLTRNLTLSVNVSAKQFRQKNFVEKVQSAVERYAVPGNLLKLELTESLLQYDIEVT
IAMMKALNKIGVQFSLDDFGTGYSSLQYLKRLPLDQFKIDQSFVRDIATDNNDKAIVKAIVAMAQILDIDVIAEGVETEE
QRQLLLGKGCVFFQGYLFSKPIPIDEFEALICRLTDT

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=439, Percent_Identity=38.2687927107062, Blast_Score=315, Evalue=7e-87,
Organism=Escherichia coli, GI87081921, Length=464, Percent_Identity=35.3448275862069, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI226510982, Length=436, Percent_Identity=32.1100917431193, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1786507, Length=296, Percent_Identity=35.1351351351351, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI87081980, Length=249, Percent_Identity=33.3333333333333, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1787055, Length=249, Percent_Identity=35.7429718875502, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI1788502, Length=252, Percent_Identity=33.3333333333333, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1790496, Length=247, Percent_Identity=35.6275303643725, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87081845, Length=242, Percent_Identity=35.5371900826446, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI87081743, Length=244, Percent_Identity=32.3770491803279, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788849, Length=450, Percent_Identity=26.6666666666667, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87082096, Length=252, Percent_Identity=30.1587301587302, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI87081977, Length=159, Percent_Identity=36.4779874213836, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788381, Length=183, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI87081881, Length=177, Percent_Identity=36.1581920903955, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1786584, Length=182, Percent_Identity=31.3186813186813, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693134, Length=170, Percent_Identity=34.1176470588235, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788956, Length=160, Percent_Identity=38.125, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=31.3953488372093, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787816, Length=174, Percent_Identity=33.9080459770115, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081974, Length=87, Percent_Identity=49.4252873563218, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789650, Length=450, Percent_Identity=20.6666666666667, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788085, Length=171, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082007, Length=181, Percent_Identity=34.2541436464088, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787410, Length=122, Percent_Identity=32.7868852459016, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 67225; Mature: 67094

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDVEYDSKLNDRKRHQADLTLSNNALAIANKDLAFQNEEKDKRAAELAIANEEKSKRA
CCCCCCCCCCCCHHHHHCCCEEECCCEEEEECCCCCCCCCHHHHHHHHHEECCCHHHHHH
AELAIANKELAFQNKEKDKRAAELAIANKELAFQNKEKDKRAAELAFQNKEKDKRAAELA
HHHHHCCCHHHCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHH
IANKELAFQNKEKDKRAAELAIANKELAIANEEKGKLTEKLNDLAFYDTLTGLPNRRILI
HCCCHHHCCCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
DRLHHALASNVREGCDSAVMFVDLDHFKDINDTLGHGFGDLLLIQIAQRLASCLRKGDTV
HHHHHHHHHHHHHCCCCEEEEEECHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCE
ARLGGDEFVLILENLDKKTIEAAAKANAIADKILAALNKPYQLDMHKCYSTVSIGAVFFD
EEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHEEEEEEEE
HQGNTAEDLLKQADIAMYQAKQAGGNQIRFFNPEMQEIINVRITLENELRLAIEKSQFHL
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHEEEEEEEECCEEEEEEECEEEE
YYQIQMDSANRVLGAEALIRWMHPERGLVLPATFIPLAEETGLILPIGKWVIETACAQIK
EEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHE
VWQKEPLTRNLTLSVNVSAKQFRQKNFVEKVQSAVERYAVPGNLLKLELTESLLQYDIEV
EECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHH
TIAMMKALNKIGVQFSLDDFGTGYSSLQYLKRLPLDQFKIDQSFVRDIATDNNDKAIVKA
HHHHHHHHHHHCCEEEEHHCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHCCCCCHHHHHH
IVAMAQILDIDVIAEGVETEEQRQLLLGKGCVFFQGYLFSKPIPIDEFEALICRLTDT
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEECHHHCCCCCHHHHHHHHHEECCC
>Mature Secondary Structure 
SKDVEYDSKLNDRKRHQADLTLSNNALAIANKDLAFQNEEKDKRAAELAIANEEKSKRA
CCCCCCCCCCCHHHHHCCCEEECCCEEEEECCCCCCCCCHHHHHHHHHEECCCHHHHHH
AELAIANKELAFQNKEKDKRAAELAIANKELAFQNKEKDKRAAELAFQNKEKDKRAAELA
HHHHHCCCHHHCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHH
IANKELAFQNKEKDKRAAELAIANKELAIANEEKGKLTEKLNDLAFYDTLTGLPNRRILI
HCCCHHHCCCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
DRLHHALASNVREGCDSAVMFVDLDHFKDINDTLGHGFGDLLLIQIAQRLASCLRKGDTV
HHHHHHHHHHHHHCCCCEEEEEECHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCE
ARLGGDEFVLILENLDKKTIEAAAKANAIADKILAALNKPYQLDMHKCYSTVSIGAVFFD
EEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHEEEEEEEE
HQGNTAEDLLKQADIAMYQAKQAGGNQIRFFNPEMQEIINVRITLENELRLAIEKSQFHL
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHEEEEEEEECCEEEEEEECEEEE
YYQIQMDSANRVLGAEALIRWMHPERGLVLPATFIPLAEETGLILPIGKWVIETACAQIK
EEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHE
VWQKEPLTRNLTLSVNVSAKQFRQKNFVEKVQSAVERYAVPGNLLKLELTESLLQYDIEV
EECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHH
TIAMMKALNKIGVQFSLDDFGTGYSSLQYLKRLPLDQFKIDQSFVRDIATDNNDKAIVKA
HHHHHHHHHHHCCEEEEHHCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHCCCCCHHHHHH
IVAMAQILDIDVIAEGVETEEQRQLLLGKGCVFFQGYLFSKPIPIDEFEALICRLTDT
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEECHHHCCCCCHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]