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The map label for this gene is cah [H]

Identifier: 119945215

GI number: 119945215

Start: 1830111

End: 1830842

Strand: Direct

Name: cah [H]

Synonym: Ping_1480

Alternate gene names: 119945215

Gene position: 1830111-1830842 (Clockwise)

Preceding gene: 119945214

Following gene: 119945217

Centisome position: 40.14

GC content: 41.39

Gene sequence:

>732_bases
ATGAAAAAATCGATTGTATTTTCTTGTTTACTTATTAGCTCTGCAGCAGTCTTGGCATCTGCTGATGTTCATTGGGAATA
TTCTGGTGAACACGGTCCTGAACATTGGGCTAAATTGAGCCCTGACAACTTTGCCTGCAGCGCATCAAATCAATCACCGG
TTAACCTAACGGGTTTTATTGAAGCGGATCTTAGGCCGATCAAATTTAATTATAAAGCAGGCGGCAGCGAAATCTTAAAT
AATGGTCATACCGTCCAAATTAACTATCAATCGGGCAGTAGCATCAATATCGATGCTACTGAGTTTGCATTATTACAGGT
GCATTTTCATGCGCCAAGTGAAAATCATATTGAGGGAAAATCCTATCCATTAGAAGCGCATTTAGTGCATGCAGATAAAG
CCGGAAACCTTGCTGTTGTCGCGGTGATGTATGAACAGAAAGATAAAAATTTAGCTTTTGCAGATGCGTGGCAGCAGATG
CCAAAGCATGCTGGTGATAAGCAGCAATTAAACCGACTCTTTAATATTGATAGTATTTTGCCCACCAACCGGGACTATTA
CCGTTTTAGTGGATCGTTAACCACTCCGCCATGCTCTGAAGGTGTCCGCTGGTTGGTTTTAAAAGAGAGTGTACCGGTAT
CTGAAGAGCAAGTTAAGGCGTTTGCAGCAGCCTTAACCGGACCAAATAATCGTTATATTCAAGCGACCAATGCGCGTATT
ATTTTAAAATAA

Upstream 100 bases:

>100_bases
TAGCCATCAGCCGTCAGCTTTCGAACTTCGAGTTTTGAATTTTCGCGCTTTAGGGCATTATAGAGCTCCACATTATATTG
TTAACATCATGGGATATATT

Downstream 100 bases:

>100_bases
TGCGGCAGATATGGGAAAATCTGTCGGCTGTCGGCTGTCGGCTGTTAGCTGTCGGCTTTAGGTTTAAGGGTTTAGGCGTT
TCACTGTCCAGTTTTTTTCC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKKSIVFSCLLISSAAVLASADVHWEYSGEHGPEHWAKLSPDNFACSASNQSPVNLTGFIEADLRPIKFNYKAGGSEILN
NGHTVQINYQSGSSINIDATEFALLQVHFHAPSENHIEGKSYPLEAHLVHADKAGNLAVVAVMYEQKDKNLAFADAWQQM
PKHAGDKQQLNRLFNIDSILPTNRDYYRFSGSLTTPPCSEGVRWLVLKESVPVSEEQVKAFAAALTGPNNRYIQATNARI
ILK

Sequences:

>Translated_243_residues
MKKSIVFSCLLISSAAVLASADVHWEYSGEHGPEHWAKLSPDNFACSASNQSPVNLTGFIEADLRPIKFNYKAGGSEILN
NGHTVQINYQSGSSINIDATEFALLQVHFHAPSENHIEGKSYPLEAHLVHADKAGNLAVVAVMYEQKDKNLAFADAWQQM
PKHAGDKQQLNRLFNIDSILPTNRDYYRFSGSLTTPPCSEGVRWLVLKESVPVSEEQVKAFAAALTGPNNRYIQATNARI
ILK
>Mature_243_residues
MKKSIVFSCLLISSAAVLASADVHWEYSGEHGPEHWAKLSPDNFACSASNQSPVNLTGFIEADLRPIKFNYKAGGSEILN
NGHTVQINYQSGSSINIDATEFALLQVHFHAPSENHIEGKSYPLEAHLVHADKAGNLAVVAVMYEQKDKNLAFADAWQQM
PKHAGDKQQLNRLFNIDSILPTNRDYYRFSGSLTTPPCSEGVRWLVLKESVPVSEEQVKAFAAALTGPNNRYIQATNARI
ILK

Specific function: Reversible hydration of carbon dioxide [H]

COG id: COG3338

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha-carbonic anhydrase family [H]

Homologues:

Organism=Homo sapiens, GI4885101, Length=244, Percent_Identity=34.0163934426229, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI258679498, Length=264, Percent_Identity=31.0606060606061, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI192447434, Length=264, Percent_Identity=31.0606060606061, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI192447432, Length=264, Percent_Identity=31.0606060606061, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI192447430, Length=264, Percent_Identity=31.0606060606061, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI4502517, Length=264, Percent_Identity=31.0606060606061, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI169636420, Length=255, Percent_Identity=32.156862745098, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI45935383, Length=230, Percent_Identity=32.6086956521739, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI4502515, Length=230, Percent_Identity=32.6086956521739, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI6912284, Length=279, Percent_Identity=28.3154121863799, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI70167127, Length=256, Percent_Identity=30.859375, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI4885099, Length=256, Percent_Identity=29.6875, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI62240989, Length=187, Percent_Identity=34.7593582887701, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI91208428, Length=250, Percent_Identity=28, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4502521, Length=207, Percent_Identity=30.4347826086957, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI38348436, Length=256, Percent_Identity=27.734375, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI22027500, Length=256, Percent_Identity=26.171875, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI4502519, Length=269, Percent_Identity=26.3940520446097, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI6005723, Length=210, Percent_Identity=27.1428571428571, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17568715, Length=245, Percent_Identity=30.6122448979592, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71995280, Length=263, Percent_Identity=27.7566539923954, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358169, Length=281, Percent_Identity=28.8256227758007, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17737413, Length=228, Percent_Identity=31.140350877193, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24645604, Length=231, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI18858185, Length=242, Percent_Identity=23.9669421487603, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650523, Length=182, Percent_Identity=27.4725274725275, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001148
- InterPro:   IPR018338
- InterPro:   IPR018340 [H]

Pfam domain/function: PF00194 Carb_anhydrase [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 26808; Mature: 26808

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00162 ALPHA_CA_1 ; PS51144 ALPHA_CA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSIVFSCLLISSAAVLASADVHWEYSGEHGPEHWAKLSPDNFACSASNQSPVNLTGFI
CCCHHEEHHHHHHHHHHEEEEEEEEEECCCCCCHHHHCCCCCCEEEECCCCCCCEEEEEE
EADLRPIKFNYKAGGSEILNNGHTVQINYQSGSSINIDATEFALLQVHFHAPSENHIEGK
ECCCEEEEEEECCCCHHHHCCCCEEEEEECCCCEEEECCCEEEEEEEEEECCCCCCCCCC
SYPLEAHLVHADKAGNLAVVAVMYEQKDKNLAFADAWQQMPKHAGDKQQLNRLFNIDSIL
CCCEEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHCHHHCC
PTNRDYYRFSGSLTTPPCSEGVRWLVLKESVPVSEEQVKAFAAALTGPNNRYIQATNARI
CCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECEEE
ILK
EEC
>Mature Secondary Structure
MKKSIVFSCLLISSAAVLASADVHWEYSGEHGPEHWAKLSPDNFACSASNQSPVNLTGFI
CCCHHEEHHHHHHHHHHEEEEEEEEEECCCCCCHHHHCCCCCCEEEECCCCCCCEEEEEE
EADLRPIKFNYKAGGSEILNNGHTVQINYQSGSSINIDATEFALLQVHFHAPSENHIEGK
ECCCEEEEEEECCCCHHHHCCCCEEEEEECCCCEEEECCCEEEEEEEEEECCCCCCCCCC
SYPLEAHLVHADKAGNLAVVAVMYEQKDKNLAFADAWQQMPKHAGDKQQLNRLFNIDSIL
CCCEEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHCHHHCC
PTNRDYYRFSGSLTTPPCSEGVRWLVLKESVPVSEEQVKAFAAALTGPNNRYIQATNARI
CCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECEEE
ILK
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9811652 [H]