Click here to switch to the map view.

The map label for this gene is recD [H]

Identifier: 119945196

GI number: 119945196

Start: 1803951

End: 1806047

Strand: Direct

Name: recD [H]

Synonym: Ping_1460

Alternate gene names: 119945196

Gene position: 1803951-1806047 (Clockwise)

Preceding gene: 119945195

Following gene: 119945197

Centisome position: 39.56

GC content: 42.68

Gene sequence:

>2097_bases
ATGTTAACACAACTAAAACAATGGAAAGAGCAGGGGCTATTACGTTCAATTGATTACCATTTTGCAGCCTTTATGGCGGA
AATGGGGGCGGATAAATTAACCCAGTTAAGTGCTGCCTTCTGCAGTGAATATCTGGGTCTTGGGCATATCTGTTTACCCG
TTGAAGAAATCATTATCCGTTTAAATGATAAATGTTCGTTAAGTGAACTTGATTTGCAGGGGTTTTGCCGGGAACATGAT
ATGGAATGTTTATTGCAGAATAATTTTGAGGCACATGCGTTATTAAGTAGTTCAATCTGTGTGGGTGATAATGCCCCCCT
GTGTTTACAGTTTAATGCCTTGTATCTTACCCGTTACGCCCTGTTTGAGCAGCTTATCGCTGATAAATTATTGGATCAAC
CTAAGTTGTCCTTGGGTTCTGATATCAAGGTGGAACTCGATGTTTTATTTGCCACCAATTATACCTATTTATGGCAGGAT
TGGTGCCGCGATCCAAGACAACCCCTGCCTTTATTATGTGAAAAATATATTGATCTTCTCCCTGGATCGACAGTTGACTG
GGTAGGAGTTGAACAGTTATTTAGTCAGGCCGAAAATGCGCAGGATTTACAACCCTTAGGATCCTTGATTCCGGAAAATA
AACGCTGTAACTGGCAAAAGGTCAGTGCTGCATTAGCCTTGACTACTGCGCGATGTGTTATCTCAGGAGGGCCCGGCACG
GGTAAAACTACGACTGTTACTAAACTGCTCGCCTTGCTGCTGAAATTTCAACCAACACTGTTGATTAAATTGGTTGCTCC
AACGGGAAAAGCTGCTGCGCGTTTAACAGAATCTATTACCCATGCCTTAGTGGAATTAAACATTGAGCCGGGCATTAAAG
ACAAAATGCCCAAGGTGGCGACGACCATTCACCGCTTGTTGGGGGTAAAAGCCAACAGTAATCACTTTCGTTTTAACCAG
GATGAAAAATTAAATGTCGATCTGCTGGTGGTGGATGAAGCTTCGATGGTCGATTTGCCGCTGATGGCAAAATTATTAAT
GGCGCTACCGGATCATGCCCGCCTGATATTATTAGGTGATAAAGACCAGCTGGCATCGGTTGAAGCGGGAGCTGTTTTAG
GGGATATTTGCCATTTTATTGAATCGGGATACAGTGCTAAAAAAGCGCAGCTGTTGGCAGATTTAACGGGTTATACCTCG
TTAACCAAGACCGCCCCTCGGTCACCTAATATGGCTGATAATTTATGTTTGCTGCGTAAAAGTTACCGTTTTGACCAATA
CTCGGGGATTGGCTATTTAGCCAAGGCGATTAATAGCGGCCGCGCAAACAGCAAAAAGGTGATGGCGTTATGTGATGATT
ATAATGATTTGCAGCACTATCCGAATACTGAGTTGGGTAAAAAAGAGTTGGCAGCTCTGGTCTTGGAAGGTTATCGTCCC
TATTTACAAAACCTGTCGACTATTACCGTAGACAATCGAAACCTTGCGGGGCAACTATTAAAGCAGTTTAACCAATTTAA
AATATTATGTGCGACGCGCGAAGGGGAGTGGGGAGTCAAGTGTTTAAATAAACTCTGCGAAACGGTATTAGAAAAAGCAG
GCCTGTTAACGACCGGGCAAGTGCACAAGGATCCGCAACATGCCTATGTTTATTGGTATGTCGGTCGTCCGGTTATGATA
ACCCAAAACAATTATCATTTAGGTTTATATAATGGTGATATTGGCCTGTGTTTATTAGATGAATCTTTACAGTTACGTGT
TTATTTCCAAATGCCCGATGCGTCTATTGCCGATTTTCAGCCAAGTCGTTTGCCCAACCATGAAACTGTTTTTGCCATGA
CGGTACATAAAAGCCAGGGATCTGAGTTTGAGCACACTGTATTAGCATTACCTGAAAATCACGTCTCTGTGGTCAGCCGA
GAACTCATTTATACCGCTATTACCCGCGCAAAAAAACAGTTGACGCTGTTTGCCGATTTATCCTTAATGGCCAGTGCGAT
GCGCCATAAAACAAAACGTTTTAGCCGTTTAGTTGAGCGTTTAAAAAGCCCATCCGTAACCCTTGCAGAAAAAGTTAAAC
AGAAAATAAAAGAATAA

Upstream 100 bases:

>100_bases
ACGGCGTTTATTTTGTTAAACCCAGTTTTAGTCTGATAGACGGGCTTGATAAACTGTTTTCAGGGCAAAAAAACAGTGCT
AAATCAACAGTGGAGCCGAT

Downstream 100 bases:

>100_bases
AGTGGCAGCTGGGATTAGCTTAATGAAAACCCCGGCTTACAAGGTGGAATGAGTTGCTTATCAAACCACAGTAATTCTCA
TTTTATTAGTCAATGCATTG

Product: exodeoxyribonuclease V, alpha subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 698; Mature: 698

Protein sequence:

>698_residues
MLTQLKQWKEQGLLRSIDYHFAAFMAEMGADKLTQLSAAFCSEYLGLGHICLPVEEIIIRLNDKCSLSELDLQGFCREHD
MECLLQNNFEAHALLSSSICVGDNAPLCLQFNALYLTRYALFEQLIADKLLDQPKLSLGSDIKVELDVLFATNYTYLWQD
WCRDPRQPLPLLCEKYIDLLPGSTVDWVGVEQLFSQAENAQDLQPLGSLIPENKRCNWQKVSAALALTTARCVISGGPGT
GKTTTVTKLLALLLKFQPTLLIKLVAPTGKAAARLTESITHALVELNIEPGIKDKMPKVATTIHRLLGVKANSNHFRFNQ
DEKLNVDLLVVDEASMVDLPLMAKLLMALPDHARLILLGDKDQLASVEAGAVLGDICHFIESGYSAKKAQLLADLTGYTS
LTKTAPRSPNMADNLCLLRKSYRFDQYSGIGYLAKAINSGRANSKKVMALCDDYNDLQHYPNTELGKKELAALVLEGYRP
YLQNLSTITVDNRNLAGQLLKQFNQFKILCATREGEWGVKCLNKLCETVLEKAGLLTTGQVHKDPQHAYVYWYVGRPVMI
TQNNYHLGLYNGDIGLCLLDESLQLRVYFQMPDASIADFQPSRLPNHETVFAMTVHKSQGSEFEHTVLALPENHVSVVSR
ELIYTAITRAKKQLTLFADLSLMASAMRHKTKRFSRLVERLKSPSVTLAEKVKQKIKE

Sequences:

>Translated_698_residues
MLTQLKQWKEQGLLRSIDYHFAAFMAEMGADKLTQLSAAFCSEYLGLGHICLPVEEIIIRLNDKCSLSELDLQGFCREHD
MECLLQNNFEAHALLSSSICVGDNAPLCLQFNALYLTRYALFEQLIADKLLDQPKLSLGSDIKVELDVLFATNYTYLWQD
WCRDPRQPLPLLCEKYIDLLPGSTVDWVGVEQLFSQAENAQDLQPLGSLIPENKRCNWQKVSAALALTTARCVISGGPGT
GKTTTVTKLLALLLKFQPTLLIKLVAPTGKAAARLTESITHALVELNIEPGIKDKMPKVATTIHRLLGVKANSNHFRFNQ
DEKLNVDLLVVDEASMVDLPLMAKLLMALPDHARLILLGDKDQLASVEAGAVLGDICHFIESGYSAKKAQLLADLTGYTS
LTKTAPRSPNMADNLCLLRKSYRFDQYSGIGYLAKAINSGRANSKKVMALCDDYNDLQHYPNTELGKKELAALVLEGYRP
YLQNLSTITVDNRNLAGQLLKQFNQFKILCATREGEWGVKCLNKLCETVLEKAGLLTTGQVHKDPQHAYVYWYVGRPVMI
TQNNYHLGLYNGDIGLCLLDESLQLRVYFQMPDASIADFQPSRLPNHETVFAMTVHKSQGSEFEHTVLALPENHVSVVSR
ELIYTAITRAKKQLTLFADLSLMASAMRHKTKRFSRLVERLKSPSVTLAEKVKQKIKE
>Mature_698_residues
MLTQLKQWKEQGLLRSIDYHFAAFMAEMGADKLTQLSAAFCSEYLGLGHICLPVEEIIIRLNDKCSLSELDLQGFCREHD
MECLLQNNFEAHALLSSSICVGDNAPLCLQFNALYLTRYALFEQLIADKLLDQPKLSLGSDIKVELDVLFATNYTYLWQD
WCRDPRQPLPLLCEKYIDLLPGSTVDWVGVEQLFSQAENAQDLQPLGSLIPENKRCNWQKVSAALALTTARCVISGGPGT
GKTTTVTKLLALLLKFQPTLLIKLVAPTGKAAARLTESITHALVELNIEPGIKDKMPKVATTIHRLLGVKANSNHFRFNQ
DEKLNVDLLVVDEASMVDLPLMAKLLMALPDHARLILLGDKDQLASVEAGAVLGDICHFIESGYSAKKAQLLADLTGYTS
LTKTAPRSPNMADNLCLLRKSYRFDQYSGIGYLAKAINSGRANSKKVMALCDDYNDLQHYPNTELGKKELAALVLEGYRP
YLQNLSTITVDNRNLAGQLLKQFNQFKILCATREGEWGVKCLNKLCETVLEKAGLLTTGQVHKDPQHAYVYWYVGRPVMI
TQNNYHLGLYNGDIGLCLLDESLQLRVYFQMPDASIADFQPSRLPNHETVFAMTVHKSQGSEFEHTVLALPENHVSVVSR
ELIYTAITRAKKQLTLFADLSLMASAMRHKTKRFSRLVERLKSPSVTLAEKVKQKIKE

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=685, Percent_Identity=39.8540145985401, Blast_Score=408, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 78024; Mature: 78024

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTQLKQWKEQGLLRSIDYHFAAFMAEMGADKLTQLSAAFCSEYLGLGHICLPVEEIIIR
CCCHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEE
LNDKCSLSELDLQGFCREHDMECLLQNNFEAHALLSSSICVGDNAPLCLQFNALYLTRYA
CCCCCCCHHCCHHHHHHHCCHHHHHHCCCCHHHHEECCEEECCCCCEEEEEHHHHHHHHH
LFEQLIADKLLDQPKLSLGSDIKVELDVLFATNYTYLWQDWCRDPRQPLPLLCEKYIDLL
HHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHC
PGSTVDWVGVEQLFSQAENAQDLQPLGSLIPENKRCNWQKVSAALALTTARCVISGGPGT
CCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEEEEECCCCC
GKTTTVTKLLALLLKFQPTLLIKLVAPTGKAAARLTESITHALVELNIEPGIKDKMPKVA
CCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCHHHH
TTIHRLLGVKANSNHFRFNQDEKLNVDLLVVDEASMVDLPLMAKLLMALPDHARLILLGD
HHHHHHHCCCCCCCCEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECC
KDQLASVEAGAVLGDICHFIESGYSAKKAQLLADLTGYTSLTKTAPRSPNMADNLCLLRK
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHH
SYRFDQYSGIGYLAKAINSGRANSKKVMALCDDYNDLQHYPNTELGKKELAALVLEGYRP
HCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHCHH
YLQNLSTITVDNRNLAGQLLKQFNQFKILCATREGEWGVKCLNKLCETVLEKAGLLTTGQ
HHCCCCEEEECCCCHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEECC
VHKDPQHAYVYWYVGRPVMITQNNYHLGLYNGDIGLCLLDESLQLRVYFQMPDASIADFQ
CCCCCCCEEEEEEECCEEEEECCCEEEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCC
PSRLPNHETVFAMTVHKSQGSEFEHTVLALPENHVSVVSRELIYTAITRAKKQLTLFADL
CCCCCCCCEEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHEEHHHHH
SLMASAMRHKTKRFSRLVERLKSPSVTLAEKVKQKIKE
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLTQLKQWKEQGLLRSIDYHFAAFMAEMGADKLTQLSAAFCSEYLGLGHICLPVEEIIIR
CCCHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEE
LNDKCSLSELDLQGFCREHDMECLLQNNFEAHALLSSSICVGDNAPLCLQFNALYLTRYA
CCCCCCCHHCCHHHHHHHCCHHHHHHCCCCHHHHEECCEEECCCCCEEEEEHHHHHHHHH
LFEQLIADKLLDQPKLSLGSDIKVELDVLFATNYTYLWQDWCRDPRQPLPLLCEKYIDLL
HHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHC
PGSTVDWVGVEQLFSQAENAQDLQPLGSLIPENKRCNWQKVSAALALTTARCVISGGPGT
CCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEEEEECCCCC
GKTTTVTKLLALLLKFQPTLLIKLVAPTGKAAARLTESITHALVELNIEPGIKDKMPKVA
CCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCHHHH
TTIHRLLGVKANSNHFRFNQDEKLNVDLLVVDEASMVDLPLMAKLLMALPDHARLILLGD
HHHHHHHCCCCCCCCEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECC
KDQLASVEAGAVLGDICHFIESGYSAKKAQLLADLTGYTSLTKTAPRSPNMADNLCLLRK
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHH
SYRFDQYSGIGYLAKAINSGRANSKKVMALCDDYNDLQHYPNTELGKKELAALVLEGYRP
HCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHCHH
YLQNLSTITVDNRNLAGQLLKQFNQFKILCATREGEWGVKCLNKLCETVLEKAGLLTTGQ
HHCCCCEEEECCCCHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEECC
VHKDPQHAYVYWYVGRPVMITQNNYHLGLYNGDIGLCLLDESLQLRVYFQMPDASIADFQ
CCCCCCCEEEEEEECCEEEEECCCEEEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCC
PSRLPNHETVFAMTVHKSQGSEFEHTVLALPENHVSVVSRELIYTAITRAKKQLTLFADL
CCCCCCCCEEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHEEHHHHH
SLMASAMRHKTKRFSRLVERLKSPSVTLAEKVKQKIKE
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]