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The map label for this gene is msrA [H]

Identifier: 119945183

GI number: 119945183

Start: 1779616

End: 1780164

Strand: Reverse

Name: msrA [H]

Synonym: Ping_1447

Alternate gene names: 119945183

Gene position: 1780164-1779616 (Counterclockwise)

Preceding gene: 119945189

Following gene: 119945173

Centisome position: 39.04

GC content: 40.8

Gene sequence:

>549_bases
ATGGCAATTTCAACAGCAACTTTTGCAGGAGGATGTTTTTGGTGTATGGAAGCGGCTTTCAATGCTTTAAAGGGCGTGAA
GAGTGCAGTTTCCGGATACACAGGCGGAAAAACGGATTCACCCACTTATGCAGATATTTGCACTGGTACAAGCGGGCATG
CTGAAGTGGTGCAAATCACATTTGATGATTCAGTCATCAGTTACGCAGAATTATTAACTATTTTTTTCAGTCTGCATGAT
GCGACACAATTAAACCGCCAGGGTCATGATATCGGCACACAGTATCGCTCTGCTATTTTTTATCACGATCTCGCGCAAAA
GCAATCAGCCTTAGAATTTATCAACACCCTTGAACAACAGGCTGTATTGACCGACAGTATCAAAACCACCATTGAAAAAT
TAGAAACATTTTACCCCGCTGAAGATTATCATCAGGGTTACTTTCTTAAAAATCCGGGACAAGGTTACTGTTCTATGGTG
ATTCAGCCTAAATTTAATAAATTTAAAGCAACATACCAAGCCGCATTAAAAGAAGAGCGCGGCAGTTAA

Upstream 100 bases:

>100_bases
TAAAGATATCGGCAACATTTAGCAGGTTAATTTAAAAAATTAAAATGGATTGTTATTATATCAATATGCTACCTTTAACA
ATTTAATACGGAGTATCAAA

Downstream 100 bases:

>100_bases
CCGATAATGGTTAACCGGTATTAATTAAAGACCAGCACTGGCCTTGCGATAGTGAGCAAACACCACCAGCAAGATACCAG
TGCAGACTAATGCGGCGGAG

Product: peptide methionine sulfoxide reductase

Products: NA

Alternate protein names: Protein-methionine-S-oxide reductase; Peptide-methionine (S)-S-oxide reductase; Peptide Met(O) reductase [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MAISTATFAGGCFWCMEAAFNALKGVKSAVSGYTGGKTDSPTYADICTGTSGHAEVVQITFDDSVISYAELLTIFFSLHD
ATQLNRQGHDIGTQYRSAIFYHDLAQKQSALEFINTLEQQAVLTDSIKTTIEKLETFYPAEDYHQGYFLKNPGQGYCSMV
IQPKFNKFKATYQAALKEERGS

Sequences:

>Translated_182_residues
MAISTATFAGGCFWCMEAAFNALKGVKSAVSGYTGGKTDSPTYADICTGTSGHAEVVQITFDDSVISYAELLTIFFSLHD
ATQLNRQGHDIGTQYRSAIFYHDLAQKQSALEFINTLEQQAVLTDSIKTTIEKLETFYPAEDYHQGYFLKNPGQGYCSMV
IQPKFNKFKATYQAALKEERGS
>Mature_181_residues
AISTATFAGGCFWCMEAAFNALKGVKSAVSGYTGGKTDSPTYADICTGTSGHAEVVQITFDDSVISYAELLTIFFSLHDA
TQLNRQGHDIGTQYRSAIFYHDLAQKQSALEFINTLEQQAVLTDSIKTTIEKLETFYPAEDYHQGYFLKNPGQGYCSMVI
QPKFNKFKATYQAALKEERGS

Specific function: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine [H]

COG id: COG0225

COG function: function code O; Peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrA Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI6912516, Length=158, Percent_Identity=46.2025316455696, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI208609995, Length=158, Percent_Identity=46.2025316455696, Blast_Score=136, Evalue=1e-32,
Organism=Homo sapiens, GI208609993, Length=113, Percent_Identity=46.0176991150442, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1790665, Length=153, Percent_Identity=46.4052287581699, Blast_Score=135, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17533973, Length=148, Percent_Identity=39.1891891891892, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320881, Length=158, Percent_Identity=39.873417721519, Blast_Score=104, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24664627, Length=166, Percent_Identity=40.3614457831325, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24664631, Length=166, Percent_Identity=39.7590361445783, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI45553131, Length=159, Percent_Identity=39.622641509434, Blast_Score=101, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002569 [H]

Pfam domain/function: PF01625 PMSR [H]

EC number: =1.8.4.11 [H]

Molecular weight: Translated: 20093; Mature: 19961

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISTATFAGGCFWCMEAAFNALKGVKSAVSGYTGGKTDSPTYADICTGTSGHAEVVQIT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCEEEEEE
FDDSVISYAELLTIFFSLHDATQLNRQGHDIGTQYRSAIFYHDLAQKQSALEFINTLEQQ
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLTDSIKTTIEKLETFYPAEDYHQGYFLKNPGQGYCSMVIQPKFNKFKATYQAALKEER
HHHHHHHHHHHHHHHHHCCCCHHCCCEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHC
GS
CC
>Mature Secondary Structure 
AISTATFAGGCFWCMEAAFNALKGVKSAVSGYTGGKTDSPTYADICTGTSGHAEVVQIT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCEEEEEE
FDDSVISYAELLTIFFSLHDATQLNRQGHDIGTQYRSAIFYHDLAQKQSALEFINTLEQQ
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLTDSIKTTIEKLETFYPAEDYHQGYFLKNPGQGYCSMVIQPKFNKFKATYQAALKEER
HHHHHHHHHHHHHHHHHCCCCHHCCCEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHC
GS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA