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The map label for this gene is lldP [C]

Identifier: 119945158

GI number: 119945158

Start: 1746496

End: 1748202

Strand: Reverse

Name: lldP [C]

Synonym: Ping_1422

Alternate gene names: 119945158

Gene position: 1748202-1746496 (Counterclockwise)

Preceding gene: 119945160

Following gene: 119945157

Centisome position: 38.34

GC content: 47.04

Gene sequence:

>1707_bases
ATGAACGAAACCCTACTCGCGTTAATCGCATTTTCACCAATACTGATATCGGGGATATTGCTGGTCGGTCTAAACTGGCC
TGCCAAACGCGCCATGCCAATCGCCTTTTTATTAACGGCTCTGATAGCGCTCTTTGTCTGGGACATGTCCGCCACCCGCG
TTATTGCATCATCCCTGCAGGGATTAATGATTACCGTTGCGGTTCTCTGGATTGTCTTCGGTGCCATTTTTCTGCTTAAT
ACCCTGAAACATACTGGCGCTATCACGGTTATTCGCAATGGGTTTACCAATATTTCCGCCGACCGGCGTGTACAGGCGAT
TATTATTGCCTGGTGTTTTGGATCCTTTATTGAAGGTGCTTCCGGTTTCGGTACACCGGCAGCGATTGCCGCCCCGCTGT
TAGTCGCTATCGGTTTCCCCGCATTAGCAGCCGTCTTAATGGGTATGATGATTCAATCAACCCCAGTTTCATTCGGCGCG
GTCGGTACACCAATCATTGTGGGTATCAATAAAGGGCTTGATACACACAACATCACTGAAACACTGGTTGCCGGCGGATC
GAACTGGGATGTCTATCTTCAGGAAATCACCTCCAATGTTGCCGTTATTCATGCCGTTGTGGGTACCTTTATTCCGGTGC
TAATGGCGATGATGTTAACCCGTTTTTTTGGTAAAAATAAAAGCTGGACAGAAGGACTAGATATCCTGCCCTTCGCTATT
TTTGCAGGTTTGGCGTTCACTGTCCCTTACGCACTGACCGGTGTTTTCCTCGGTCCTGAATTCCCAGCATTAATTGGTGG
CTTAGTCAGCCTTGCTATTGTGGTCACCGCCGCGAAAAAAGGTTTCCTTGTACCGAAAACAAAGTGGGATTTTGAAAGTG
AAAATAACTGGCCGAAAGAATGGTTGGGTTCACTGAAAATAGATTTAAAAGAGAATAACAAAAAACCAATGAGCATGGTG
CTTGCCTGGGCACCTTATGTATTGTTAGCAGTGATTCTGGTAGCAAGCCGAGTTAATGCAGACTTCAAAGGTTTTTTAAC
GGGTATCAGCTTATCCTTCAGCAATATTTTAGGCGAAGCGGGTGTTAGCGCAGCCATTCAGCCGCTCTATTTGCCCGGTG
GTATTCTGGTCTTTGTGGCACTGCTTGCGGTTATCCTGCAATCACGTAGCATCAAACCCTTGGCCGGTGCCTTCGGTGAG
TCAAGCAGAACATTAGTTGGGGCAGGTTTTGTACTGATGTTTACTATTCCTATGGTACGTATCTTTATTAACTCCGGTGT
TAATGCGGCAGATTTAGCCAGCATGCCGGTGACAACGGCTAACTTCGTATCAGGTTTAGTGGGTGACTTTTTCCCGGCAC
TCAGTGCATCAATTGGCGCACTGGGCGCATTTATTGCGGGTTCTAATACGGTTTCCAATATGATGCTTGGCCAGTTTCAA
TTTGAAGTAGCGCAAACATTATCGATTTCAACGGCGGCAGTTGTCTCACTTCAGGCGGTGGGTGCCGCGGCAGGTAATAT
GATTGCTATCCACAACGTAGTAGCAGCCTCTGCAACGGTGGGACTATTGGGCCGCGAAGGTTTGATATTGCGTAAAACAG
CTATCCCGACCTTCTATTACCTTATTGCGACCGGCGTGATTGGTTTAGTGATTATCTATGGTTTTAATATCACCGATGTT
CTGATGGCAGCAGAACAAGCTCAATAA

Upstream 100 bases:

>100_bases
TCACAAACTGCGTACATAGCCAAACAACAACCAAAAAGATTTTGGCTATGTACGCAGACTATAACAACATAACAATATAC
ATTGGAAGGATTACACTATT

Downstream 100 bases:

>100_bases
TAGCGTACCGCTATCACAAAATTTCAGCATTAGCTTAGGTTTATTCTCCGGCTCATGCTGAAATAATAACGACGAATTCG
AATGACTTTTTTATTCGCAA

Product: L-lactate transport

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MNETLLALIAFSPILISGILLVGLNWPAKRAMPIAFLLTALIALFVWDMSATRVIASSLQGLMITVAVLWIVFGAIFLLN
TLKHTGAITVIRNGFTNISADRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGA
VGTPIIVGINKGLDTHNITETLVAGGSNWDVYLQEITSNVAVIHAVVGTFIPVLMAMMLTRFFGKNKSWTEGLDILPFAI
FAGLAFTVPYALTGVFLGPEFPALIGGLVSLAIVVTAAKKGFLVPKTKWDFESENNWPKEWLGSLKIDLKENNKKPMSMV
LAWAPYVLLAVILVASRVNADFKGFLTGISLSFSNILGEAGVSAAIQPLYLPGGILVFVALLAVILQSRSIKPLAGAFGE
SSRTLVGAGFVLMFTIPMVRIFINSGVNAADLASMPVTTANFVSGLVGDFFPALSASIGALGAFIAGSNTVSNMMLGQFQ
FEVAQTLSISTAAVVSLQAVGAAAGNMIAIHNVVAASATVGLLGREGLILRKTAIPTFYYLIATGVIGLVIIYGFNITDV
LMAAEQAQ

Sequences:

>Translated_568_residues
MNETLLALIAFSPILISGILLVGLNWPAKRAMPIAFLLTALIALFVWDMSATRVIASSLQGLMITVAVLWIVFGAIFLLN
TLKHTGAITVIRNGFTNISADRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGA
VGTPIIVGINKGLDTHNITETLVAGGSNWDVYLQEITSNVAVIHAVVGTFIPVLMAMMLTRFFGKNKSWTEGLDILPFAI
FAGLAFTVPYALTGVFLGPEFPALIGGLVSLAIVVTAAKKGFLVPKTKWDFESENNWPKEWLGSLKIDLKENNKKPMSMV
LAWAPYVLLAVILVASRVNADFKGFLTGISLSFSNILGEAGVSAAIQPLYLPGGILVFVALLAVILQSRSIKPLAGAFGE
SSRTLVGAGFVLMFTIPMVRIFINSGVNAADLASMPVTTANFVSGLVGDFFPALSASIGALGAFIAGSNTVSNMMLGQFQ
FEVAQTLSISTAAVVSLQAVGAAAGNMIAIHNVVAASATVGLLGREGLILRKTAIPTFYYLIATGVIGLVIIYGFNITDV
LMAAEQAQ
>Mature_568_residues
MNETLLALIAFSPILISGILLVGLNWPAKRAMPIAFLLTALIALFVWDMSATRVIASSLQGLMITVAVLWIVFGAIFLLN
TLKHTGAITVIRNGFTNISADRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGA
VGTPIIVGINKGLDTHNITETLVAGGSNWDVYLQEITSNVAVIHAVVGTFIPVLMAMMLTRFFGKNKSWTEGLDILPFAI
FAGLAFTVPYALTGVFLGPEFPALIGGLVSLAIVVTAAKKGFLVPKTKWDFESENNWPKEWLGSLKIDLKENNKKPMSMV
LAWAPYVLLAVILVASRVNADFKGFLTGISLSFSNILGEAGVSAAIQPLYLPGGILVFVALLAVILQSRSIKPLAGAFGE
SSRTLVGAGFVLMFTIPMVRIFINSGVNAADLASMPVTTANFVSGLVGDFFPALSASIGALGAFIAGSNTVSNMMLGQFQ
FEVAQTLSISTAAVVSLQAVGAAAGNMIAIHNVVAASATVGLLGREGLILRKTAIPTFYYLIATGVIGLVIIYGFNITDV
LMAAEQAQ

Specific function: May play a role in L-lactate transport [H]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lactate permease family [H]

Homologues:

Organism=Escherichia coli, GI1790031, Length=571, Percent_Identity=26.4448336252189, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789347, Length=582, Percent_Identity=27.4914089347079, Blast_Score=143, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003804 [H]

Pfam domain/function: PF02652 Lactate_perm [H]

EC number: NA

Molecular weight: Translated: 59651; Mature: 59651

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETLLALIAFSPILISGILLVGLNWPAKRAMPIAFLLTALIALFVWDMSATRVIASSLQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GLMITVAVLWIVFGAIFLLNTLKHTGAITVIRNGFTNISADRRVQAIIIAWCFGSFIEGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
SGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGAVGTPIIVGINKGLDTHNITE
CCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHH
TLVAGGSNWDVYLQEITSNVAVIHAVVGTFIPVLMAMMLTRFFGKNKSWTEGLDILPFAI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
FAGLAFTVPYALTGVFLGPEFPALIGGLVSLAIVVTAAKKGFLVPKTKWDFESENNWPKE
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
WLGSLKIDLKENNKKPMSMVLAWAPYVLLAVILVASRVNADFKGFLTGISLSFSNILGEA
HHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
GVSAAIQPLYLPGGILVFVALLAVILQSRSIKPLAGAFGESSRTLVGAGFVLMFTIPMVR
CHHHCCCCEECCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEHHHHHHHHHHHHHH
IFINSGVNAADLASMPVTTANFVSGLVGDFFPALSASIGALGAFIAGSNTVSNMMLGQFQ
HHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FEVAQTLSISTAAVVSLQAVGAAAGNMIAIHNVVAASATVGLLGREGLILRKTAIPTFYY
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHH
LIATGVIGLVIIYGFNITDVLMAAEQAQ
HHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNETLLALIAFSPILISGILLVGLNWPAKRAMPIAFLLTALIALFVWDMSATRVIASSLQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GLMITVAVLWIVFGAIFLLNTLKHTGAITVIRNGFTNISADRRVQAIIIAWCFGSFIEGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
SGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGAVGTPIIVGINKGLDTHNITE
CCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHH
TLVAGGSNWDVYLQEITSNVAVIHAVVGTFIPVLMAMMLTRFFGKNKSWTEGLDILPFAI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
FAGLAFTVPYALTGVFLGPEFPALIGGLVSLAIVVTAAKKGFLVPKTKWDFESENNWPKE
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
WLGSLKIDLKENNKKPMSMVLAWAPYVLLAVILVASRVNADFKGFLTGISLSFSNILGEA
HHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
GVSAAIQPLYLPGGILVFVALLAVILQSRSIKPLAGAFGESSRTLVGAGFVLMFTIPMVR
CHHHCCCCEECCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEHHHHHHHHHHHHHH
IFINSGVNAADLASMPVTTANFVSGLVGDFFPALSASIGALGAFIAGSNTVSNMMLGQFQ
HHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FEVAQTLSISTAAVVSLQAVGAAAGNMIAIHNVVAASATVGLLGREGLILRKTAIPTFYY
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHH
LIATGVIGLVIIYGFNITDVLMAAEQAQ
HHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]