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The map label for this gene is int [H]

Identifier: 119945130

GI number: 119945130

Start: 1711236

End: 1712210

Strand: Reverse

Name: int [H]

Synonym: Ping_1393

Alternate gene names: 119945130

Gene position: 1712210-1711236 (Counterclockwise)

Preceding gene: 119945148

Following gene: 119945129

Centisome position: 37.55

GC content: 35.28

Gene sequence:

>975_bases
ATGAAGTCTCCATTTTTAAATGCCGTAGCAGAAAGTATGCGTGTTAAATTTTATGCAGAAAAAACAATCAAGGCTTATAT
CTATTGGATAAAGTCCTATATTTACTTTAATAATAAGAAGCACCCATTCGAATGTCATAATGCTGAAGTAGAAGCGTTCC
TTTCATACCTCGCCAATAGCAAAAAAGTAGCCCCAAAAACGCAAGCATTAGCGCTTAATGCATTAGTTTATTTATACCGA
GAATTCTTAGATAACCCCTTAACATTATCACTCAACTTTAAAAGAACAAATACGCAGCCTAAGTTACCCATCGTATTAAC
TATTGATGAAGTTAGCCTATTACTTAAGTCTCTATCAAGTTCAGTAACATTACCTTGTTACCTCTTATATGGCAGTGGAT
TAAGATTAATGGAAGCAGTCAATTTACGAATTCAAGATATTAACTTTGATTATCTATCAATAAATATTTGGCAAGGGAAA
GGAGGAAAGCACCGCAGCGTAACATTAGCACCTGAATTAATAGAATCATTACAGAATCAGATTACTAAAGTTAATTTATA
TTATCAGCAAGATATGCAACGGACCGATTATCAAGGGGTATATTTACCTCATGCGCTGGCAGGTAAATACCCGAATGCAG
CTAAAGAACTAAAATGGCACTATTTATTTCCTTCTACACAGCTGTCATTTGAACCTGGCACTACAAATCTAAGACGTCAC
CATATGCATGAAAGTAATATACAAAAAGCAGTAAAAAATGCAGCACGTACTTTAGACTTTAAAAAACAAGTTACTTGCCA
TACATTACGACACTCTTTTGCAACACACTTATTGCAGCGTGGTACAGATATTCGCACGGTGCAAGAGCAATTAGGACACA
CTGATCTCCGTACCACTCAGATCTATACACATGTATTACAAGCAGGTGCTAACTGTGTAAGAAGTCCTCTATCGGATTTA
ATAAAAAAAGATTGA

Upstream 100 bases:

>100_bases
TCATGTTGATAGATGAAAAAAGTCCGTATTAACGGCAGAAACACGGAATAACACATATACTGTATATAAGATCATGTAAA
AAATAACAGCGGAGAAATAA

Downstream 100 bases:

>100_bases
AAAAGATTGGACATCCACTTATATTTCATCATTAATTCAATAGATTAGAATGCAAAACCAGTGCGGCTACGAAAATTTCC
GACCGTTTTTCTTGTGATGG

Product: integron integrase

Products: NA

Alternate protein names: E2 protein [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKSPFLNAVAESMRVKFYAEKTIKAYIYWIKSYIYFNNKKHPFECHNAEVEAFLSYLANSKKVAPKTQALALNALVYLYR
EFLDNPLTLSLNFKRTNTQPKLPIVLTIDEVSLLLKSLSSSVTLPCYLLYGSGLRLMEAVNLRIQDINFDYLSINIWQGK
GGKHRSVTLAPELIESLQNQITKVNLYYQQDMQRTDYQGVYLPHALAGKYPNAAKELKWHYLFPSTQLSFEPGTTNLRRH
HMHESNIQKAVKNAARTLDFKKQVTCHTLRHSFATHLLQRGTDIRTVQEQLGHTDLRTTQIYTHVLQAGANCVRSPLSDL
IKKD

Sequences:

>Translated_324_residues
MKSPFLNAVAESMRVKFYAEKTIKAYIYWIKSYIYFNNKKHPFECHNAEVEAFLSYLANSKKVAPKTQALALNALVYLYR
EFLDNPLTLSLNFKRTNTQPKLPIVLTIDEVSLLLKSLSSSVTLPCYLLYGSGLRLMEAVNLRIQDINFDYLSINIWQGK
GGKHRSVTLAPELIESLQNQITKVNLYYQQDMQRTDYQGVYLPHALAGKYPNAAKELKWHYLFPSTQLSFEPGTTNLRRH
HMHESNIQKAVKNAARTLDFKKQVTCHTLRHSFATHLLQRGTDIRTVQEQLGHTDLRTTQIYTHVLQAGANCVRSPLSDL
IKKD
>Mature_324_residues
MKSPFLNAVAESMRVKFYAEKTIKAYIYWIKSYIYFNNKKHPFECHNAEVEAFLSYLANSKKVAPKTQALALNALVYLYR
EFLDNPLTLSLNFKRTNTQPKLPIVLTIDEVSLLLKSLSSSVTLPCYLLYGSGLRLMEAVNLRIQDINFDYLSINIWQGK
GGKHRSVTLAPELIESLQNQITKVNLYYQQDMQRTDYQGVYLPHALAGKYPNAAKELKWHYLFPSTQLSFEPGTTNLRRH
HMHESNIQKAVKNAARTLDFKKQVTCHTLRHSFATHLLQRGTDIRTVQEQLGHTDLRTTQIYTHVLQAGANCVRSPLSDL
IKKD

Specific function: Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=239, Percent_Identity=31.7991631799163, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR011946
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 37267; Mature: 37267

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSPFLNAVAESMRVKFYAEKTIKAYIYWIKSYIYFNNKKHPFECHNAEVEAFLSYLANS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHCC
KKVAPKTQALALNALVYLYREFLDNPLTLSLNFKRTNTQPKLPIVLTIDEVSLLLKSLSS
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHCC
SVTLPCYLLYGSGLRLMEAVNLRIQDINFDYLSINIWQGKGGKHRSVTLAPELIESLQNQ
CCCEEEEEEECCCHHHHHHHCCEEEEECEEEEEEEEEECCCCCCCEEEECHHHHHHHHHH
ITKVNLYYQQDMQRTDYQGVYLPHALAGKYPNAAKELKWHYLFPSTQLSFEPGTTNLRRH
HHEEEEEEHHCCCCCCCCCEECCHHHHCCCCCHHHHCEEEEECCCCEEEECCCCCHHHHH
HMHESNIQKAVKNAARTLDFKKQVTCHTLRHSFATHLLQRGTDIRTVQEQLGHTDLRTTQ
HCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHH
IYTHVLQAGANCVRSPLSDLIKKD
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSPFLNAVAESMRVKFYAEKTIKAYIYWIKSYIYFNNKKHPFECHNAEVEAFLSYLANS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHCC
KKVAPKTQALALNALVYLYREFLDNPLTLSLNFKRTNTQPKLPIVLTIDEVSLLLKSLSS
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHCC
SVTLPCYLLYGSGLRLMEAVNLRIQDINFDYLSINIWQGKGGKHRSVTLAPELIESLQNQ
CCCEEEEEEECCCHHHHHHHCCEEEEECEEEEEEEEEECCCCCCCEEEECHHHHHHHHHH
ITKVNLYYQQDMQRTDYQGVYLPHALAGKYPNAAKELKWHYLFPSTQLSFEPGTTNLRRH
HHEEEEEEHHCCCCCCCCCEECCHHHHCCCCCHHHHCEEEEECCCCEEEECCCCCHHHHH
HMHESNIQKAVKNAARTLDFKKQVTCHTLRHSFATHLLQRGTDIRTVQEQLGHTDLRTTQ
HCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHH
IYTHVLQAGANCVRSPLSDLIKKD
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2821509; 2823258; 3054482; 8195081; 2188588 [H]