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The map label for this gene is silB [H]

Identifier: 119945109

GI number: 119945109

Start: 1686227

End: 1687693

Strand: Direct

Name: silB [H]

Synonym: Ping_1369

Alternate gene names: 119945109

Gene position: 1686227-1687693 (Clockwise)

Preceding gene: 119945108

Following gene: 119945110

Centisome position: 36.98

GC content: 41.72

Gene sequence:

>1467_bases
ATGCGTTACTTTTTAGTTTTAATTGTTGGTTTATTTTTGGGGATCGTCGCTACCAAGAATCAGCAAATCAATAGTTTGTT
TAGTGCAACACAAAAAACAGCAGAGCCGGAAGTTTTATATTGGGTTGCCCCAATGGATGCAAATTATCAGCGTGATAAAC
CGGGTAAATCCCCGATGGGCATGGATTTAGTGCCTGTTTATGCAGAAAAAAGTGCTGAAGCTGAAAAAGCTGAGCCTAAA
ATTTTATATTGGGTTGCCCCGATGGATGCGAATTATCAGCGTGATAAACCGGGTAAGTCCCCGATGGGCATGGACTTAGT
CCCTGTCTTTGAGGAAGCAGGAGGCGAGTCTGAAGCGGGCTTAGTTAAAATCTCACCGGCGGTTGAAAATAATCTTGGCG
TACGTACAGGAAAGGTGGTTAATGCACCGTTAAATATCTCCATCAACACATTAGGAACAGTACAGGCCAATGAGAATGCG
CTGTGGCAAATCAATAGCCGAGTCTCGGGATGGATTGAAAAACTTTATGTTAAATCCGTGGGCGTTGAAGTTGAAAAAGG
GCAAGCGCTGTTTGATCTTTATTCCCCAGAGTTAGTGAAAGCACAGGAATCATTATTTAATGCGATTAATTTAAATCGTA
GCAATTTAATTACTTCGTCAAAAGCGCGTTTACAGGCATTAGGGGTAAATCAGGATCAAATTGAAAATATAATCAGAAAT
AAAAAAGTATTACAAAATATCACCGTCTTCGCACCGCAAAAAGGCACTATTTCGGAGCTTAAATTAAATGAAGGGGCGTT
TATTTCGCCTTCTACTGTGGTGATCACTGCGGTTAATTTAGATACGGTTTGGGTGGACGTTGAAGTGTTTGCCGCACAAG
TATCATTAGTTAAGCTCGGCGATTTAGCATCTATGACCTTAGATTATTTTCCGGGACAGAAATGGGAAGGGCAGGTTGAT
TTTATCTACCCTGAAATGAACGCCAGTAATCGTACCCTGAGGGTTCGTCTGCAATTTGATAATCCCACTGCATTATTAAA
ACCTAATATGTTTGCCAGTGTCACACTGATCCCGCAAATGAAGCAAAGAACACTGCAAATTCCTCGGGAAGCGGTAATTT
ATGCCGGTAACATGAATCGCGTCGTATTAGCCTTAGGTGAGGGTAATTTTAAGTCTGTGCTGGTTAATTTAGGGCTGGAA
AACAAAAAATCGGTGGAAGTTTTGTCGGGTTTAAGTGAAGGGCAGGAAATAGTCACCTCGGCGCAATTTCTATTAGATTC
AGAGTCCAGCATCAGTGCAGATTTTGGGCGAATGTTAGAGCTTGATAAAAACAAACAAAGTCAGCCTGAGTCCGATTCAA
TCGGTGAAGATGAAGATCTCGATTGGCTTGATTTAGGTGAGCAGTCTGATTTTGGTTTATCAGGAAACAACACTTCAGGA
CCCGTTGCTCGGAAGGTGACATTATGA

Upstream 100 bases:

>100_bases
CGAGCAGAACCTGACCTTAGAATATCAACAACTGTATTTCGATGGCCTTAAAAGCCTGTCTAACATCCGTTATTTCCAGG
CACTTTAATAGGAAAATATT

Downstream 100 bases:

>100_bases
TTGGTAAAATTATAAATTGGTCAATTAAAAACCGTATTCTGGTTTTATTGATAACCGCAGCGATTGTCGCTTACGGGGTG
TTCTCTGTTCAGAAAACACC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MRYFLVLIVGLFLGIVATKNQQINSLFSATQKTAEPEVLYWVAPMDANYQRDKPGKSPMGMDLVPVYAEKSAEAEKAEPK
ILYWVAPMDANYQRDKPGKSPMGMDLVPVFEEAGGESEAGLVKISPAVENNLGVRTGKVVNAPLNISINTLGTVQANENA
LWQINSRVSGWIEKLYVKSVGVEVEKGQALFDLYSPELVKAQESLFNAINLNRSNLITSSKARLQALGVNQDQIENIIRN
KKVLQNITVFAPQKGTISELKLNEGAFISPSTVVITAVNLDTVWVDVEVFAAQVSLVKLGDLASMTLDYFPGQKWEGQVD
FIYPEMNASNRTLRVRLQFDNPTALLKPNMFASVTLIPQMKQRTLQIPREAVIYAGNMNRVVLALGEGNFKSVLVNLGLE
NKKSVEVLSGLSEGQEIVTSAQFLLDSESSISADFGRMLELDKNKQSQPESDSIGEDEDLDWLDLGEQSDFGLSGNNTSG
PVARKVTL

Sequences:

>Translated_488_residues
MRYFLVLIVGLFLGIVATKNQQINSLFSATQKTAEPEVLYWVAPMDANYQRDKPGKSPMGMDLVPVYAEKSAEAEKAEPK
ILYWVAPMDANYQRDKPGKSPMGMDLVPVFEEAGGESEAGLVKISPAVENNLGVRTGKVVNAPLNISINTLGTVQANENA
LWQINSRVSGWIEKLYVKSVGVEVEKGQALFDLYSPELVKAQESLFNAINLNRSNLITSSKARLQALGVNQDQIENIIRN
KKVLQNITVFAPQKGTISELKLNEGAFISPSTVVITAVNLDTVWVDVEVFAAQVSLVKLGDLASMTLDYFPGQKWEGQVD
FIYPEMNASNRTLRVRLQFDNPTALLKPNMFASVTLIPQMKQRTLQIPREAVIYAGNMNRVVLALGEGNFKSVLVNLGLE
NKKSVEVLSGLSEGQEIVTSAQFLLDSESSISADFGRMLELDKNKQSQPESDSIGEDEDLDWLDLGEQSDFGLSGNNTSG
PVARKVTL
>Mature_488_residues
MRYFLVLIVGLFLGIVATKNQQINSLFSATQKTAEPEVLYWVAPMDANYQRDKPGKSPMGMDLVPVYAEKSAEAEKAEPK
ILYWVAPMDANYQRDKPGKSPMGMDLVPVFEEAGGESEAGLVKISPAVENNLGVRTGKVVNAPLNISINTLGTVQANENA
LWQINSRVSGWIEKLYVKSVGVEVEKGQALFDLYSPELVKAQESLFNAINLNRSNLITSSKARLQALGVNQDQIENIIRN
KKVLQNITVFAPQKGTISELKLNEGAFISPSTVVITAVNLDTVWVDVEVFAAQVSLVKLGDLASMTLDYFPGQKWEGQVD
FIYPEMNASNRTLRVRLQFDNPTALLKPNMFASVTLIPQMKQRTLQIPREAVIYAGNMNRVVLALGEGNFKSVLVNLGLE
NKKSVEVLSGLSEGQEIVTSAQFLLDSESSISADFGRMLELDKNKQSQPESDSIGEDEDLDWLDLGEQSDFGLSGNNTSG
PVARKVTL

Specific function: Component of the sil cation efflux system that confers resistance to silver. May be part of a three-component cation/proton antiporter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=377, Percent_Identity=34.4827586206897, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 53609; Mature: 53609

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYFLVLIVGLFLGIVATKNQQINSLFSATQKTAEPEVLYWVAPMDANYQRDKPGKSPMG
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCC
MDLVPVYAEKSAEAEKAEPKILYWVAPMDANYQRDKPGKSPMGMDLVPVFEEAGGESEAG
CCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEHHHHHCCCCCCCC
LVKISPAVENNLGVRTGKVVNAPLNISINTLGTVQANENALWQINSRVSGWIEKLYVKSV
EEEECCCCCCCCCCCCCEEEECCEEEEEEEEEEEEECCCEEEEECCHHHHHHHHHHHHHC
GVEVEKGQALFDLYSPELVKAQESLFNAINLNRSNLITSSKARLQALGVNQDQIENIIRN
CEEEECCCEEEECCCCHHHHHHHHHHHHHCCCHHHEEECCCCEEEEECCCHHHHHHHHHH
KKVLQNITVFAPQKGTISELKLNEGAFISPSTVVITAVNLDTVWVDVEVFAAQVSLVKLG
HHHHHCEEEEECCCCCCEEEEECCCCEECCCEEEEEEEECCEEEEEEEEEEEEEEEEEEC
DLASMTLDYFPGQKWEGQVDFIYPEMNASNRTLRVRLQFDNPTALLKPNMFASVTLIPQM
CHHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEEEEECCCCEEECCCCEEEEEECHHH
KQRTLQIPREAVIYAGNMNRVVLALGEGNFKSVLVNLGLENKKSVEVLSGLSEGQEIVTS
HHHHHCCCCEEEEEECCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHH
AQFLLDSESSISADFGRMLELDKNKQSQPESDSIGEDEDLDWLDLGEQSDFGLSGNNTSG
HHHHCCCCCCCCHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCC
PVARKVTL
CCEEEECC
>Mature Secondary Structure
MRYFLVLIVGLFLGIVATKNQQINSLFSATQKTAEPEVLYWVAPMDANYQRDKPGKSPMG
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCC
MDLVPVYAEKSAEAEKAEPKILYWVAPMDANYQRDKPGKSPMGMDLVPVFEEAGGESEAG
CCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEHHHHHCCCCCCCC
LVKISPAVENNLGVRTGKVVNAPLNISINTLGTVQANENALWQINSRVSGWIEKLYVKSV
EEEECCCCCCCCCCCCCEEEECCEEEEEEEEEEEEECCCEEEEECCHHHHHHHHHHHHHC
GVEVEKGQALFDLYSPELVKAQESLFNAINLNRSNLITSSKARLQALGVNQDQIENIIRN
CEEEECCCEEEECCCCHHHHHHHHHHHHHCCCHHHEEECCCCEEEEECCCHHHHHHHHHH
KKVLQNITVFAPQKGTISELKLNEGAFISPSTVVITAVNLDTVWVDVEVFAAQVSLVKLG
HHHHHCEEEEECCCCCCEEEEECCCCEECCCEEEEEEEECCEEEEEEEEEEEEEEEEEEC
DLASMTLDYFPGQKWEGQVDFIYPEMNASNRTLRVRLQFDNPTALLKPNMFASVTLIPQM
CHHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEEEEECCCCEEECCCCEEEEEECHHH
KQRTLQIPREAVIYAGNMNRVVLALGEGNFKSVLVNLGLENKKSVEVLSGLSEGQEIVTS
HHHHHCCCCEEEEEECCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHH
AQFLLDSESSISADFGRMLELDKNKQSQPESDSIGEDEDLDWLDLGEQSDFGLSGNNTSG
HHHHCCCCCCCCHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCC
PVARKVTL
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]