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The map label for this gene is pepB [H]

Identifier: 119945075

GI number: 119945075

Start: 1648675

End: 1649967

Strand: Direct

Name: pepB [H]

Synonym: Ping_1331

Alternate gene names: 119945075

Gene position: 1648675-1649967 (Clockwise)

Preceding gene: 119945074

Following gene: 119945076

Centisome position: 36.16

GC content: 43.08

Gene sequence:

>1293_bases
ATGAGCAATGTTTTTTTAGTTTCTTTAAGTTTTGCAACGGCATCAGTAATCTGGGGAAAGGGCGCTCTGCTGAGTTTTTC
CGAGGGTCATGCAACTATCCATTTGAATAAAGATAACCCCTTATTCCGCCAGGTTCAAGCAGCGGCGCGCAAGTTAGATG
GTATGTCACTTGAAGGTATTAAATTAGATGGTTCTCTCTGGGATAAAGAGCTACGTTGGGCATTTTCTCAGGGTTTTTAT
AATGCTAAAAAAGGCGCTAATATAGATTTTTCTGAATTGGATCCCGCTCAATTGCAAAACCTTACGGCGCAAAAAAAGAT
TGTTGAATGGGTACGTGAAACGATTAATCTTGGGCCGGAAGCTTTAGCGCCTAATGTACTTTGTGATAAAGCGGTTAAAT
TAATCGAGTCTGTTTTACCTGAAGGTATCGCTATTTCCCATAAGATAATCGAAGGTGAAGACTTATTAATAGAAAACTAT
CAGGGAATTTATCAGGTTGGTCGAGGCAGTACACGTCCGCCCTGTATGTTACAACTGGATTTTAATCCAACGGGTGATCC
TGATGCAGCCGTTGACTATGCTTTAGTCGGTAAAGGGATCACTTTTGATTCAGGTGGTTATAGTTTAAAACCGAGCGGTT
CAATGGCCATAATGAAAAGTGATATGGGGGGAGCTGCGACACTGACTGGCGCATTAGCACTGGCCATTGTGAACGGCTTA
AATAAGCGGGTTAAATTATACCTGTGCTGCGCGGAAAATTTGGTTAGCGGTCATGCCTATAAATTGGGCGATGTGATCAC
TTATAAAAATGGCGTCACCGTTGAAGTATTAAACAGTGATGCTGAAGGGCGTTTAGTATTGGCCGATGGTCTGATTGCAG
CGCAGGAAGATAACGCAGGCATTATTATTGATGCGGCAACCTTAACCGGGGCCGCTAAAATGGCGGTTGGTCGTGATTAT
AACTGTGTACTAAGCATGGATGATCAATTGGCTGAGCTTGCAAGTCGCTGTGCTAAGCAGGAAAATGAATATCTGTGGCG
TCTACCACTAGAAGAGTTTCATTTCCAGCAAATTGGCTCCTCATTTGCAGATATTGCTAATATTCATAGTGGTGAGGGAA
TGGCAGGGGCTTCAACGGCGGCGGCATTTTTAGCGAATTTTGTTATTAATCCACAATCAAATTGGATACATTTTGATCTC
TCGGGCAGTTATCAGCTGAGTGAAAATGGGTTATGGGCGACCGGCGGTAAAGGTCACGGTGTGCGCACTATCAGTAAAAT
GTTATTCGCTTAA

Upstream 100 bases:

>100_bases
ATATCCAAATTACCTGGAGTCTGAATCTTCAATTGGTTTGGTTATCTGATTTTTAAAAACGCAAGCTTCGGCTTGCGTTT
TTTTTTGAAAAGGAAATAAT

Downstream 100 bases:

>100_bases
ACTATCCAGTAACTGTGGACTTTTCGCATGTTAATTTAGCTGCGCTTCTAAAGATCATTTTAGGGGCGGTGTCATGGAGC
AAATATAAAATTTGCTACAA

Product: aminopeptidase B

Products: NA

Alternate protein names: Aminopeptidase B [H]

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MSNVFLVSLSFATASVIWGKGALLSFSEGHATIHLNKDNPLFRQVQAAARKLDGMSLEGIKLDGSLWDKELRWAFSQGFY
NAKKGANIDFSELDPAQLQNLTAQKKIVEWVRETINLGPEALAPNVLCDKAVKLIESVLPEGIAISHKIIEGEDLLIENY
QGIYQVGRGSTRPPCMLQLDFNPTGDPDAAVDYALVGKGITFDSGGYSLKPSGSMAIMKSDMGGAATLTGALALAIVNGL
NKRVKLYLCCAENLVSGHAYKLGDVITYKNGVTVEVLNSDAEGRLVLADGLIAAQEDNAGIIIDAATLTGAAKMAVGRDY
NCVLSMDDQLAELASRCAKQENEYLWRLPLEEFHFQQIGSSFADIANIHSGEGMAGASTAAAFLANFVINPQSNWIHFDL
SGSYQLSENGLWATGGKGHGVRTISKMLFA

Sequences:

>Translated_430_residues
MSNVFLVSLSFATASVIWGKGALLSFSEGHATIHLNKDNPLFRQVQAAARKLDGMSLEGIKLDGSLWDKELRWAFSQGFY
NAKKGANIDFSELDPAQLQNLTAQKKIVEWVRETINLGPEALAPNVLCDKAVKLIESVLPEGIAISHKIIEGEDLLIENY
QGIYQVGRGSTRPPCMLQLDFNPTGDPDAAVDYALVGKGITFDSGGYSLKPSGSMAIMKSDMGGAATLTGALALAIVNGL
NKRVKLYLCCAENLVSGHAYKLGDVITYKNGVTVEVLNSDAEGRLVLADGLIAAQEDNAGIIIDAATLTGAAKMAVGRDY
NCVLSMDDQLAELASRCAKQENEYLWRLPLEEFHFQQIGSSFADIANIHSGEGMAGASTAAAFLANFVINPQSNWIHFDL
SGSYQLSENGLWATGGKGHGVRTISKMLFA
>Mature_429_residues
SNVFLVSLSFATASVIWGKGALLSFSEGHATIHLNKDNPLFRQVQAAARKLDGMSLEGIKLDGSLWDKELRWAFSQGFYN
AKKGANIDFSELDPAQLQNLTAQKKIVEWVRETINLGPEALAPNVLCDKAVKLIESVLPEGIAISHKIIEGEDLLIENYQ
GIYQVGRGSTRPPCMLQLDFNPTGDPDAAVDYALVGKGITFDSGGYSLKPSGSMAIMKSDMGGAATLTGALALAIVNGLN
KRVKLYLCCAENLVSGHAYKLGDVITYKNGVTVEVLNSDAEGRLVLADGLIAAQEDNAGIIIDAATLTGAAKMAVGRDYN
CVLSMDDQLAELASRCAKQENEYLWRLPLEEFHFQQIGSSFADIANIHSGEGMAGASTAAAFLANFVINPQSNWIHFDLS
GSYQLSENGLWATGGKGHGVRTISKMLFA

Specific function: Probably plays an important role in intracellular peptide degradation [H]

COG id: COG0260

COG function: function code E; Leucyl aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M17 family [H]

Homologues:

Organism=Homo sapiens, GI41393561, Length=314, Percent_Identity=36.3057324840764, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI47155554, Length=270, Percent_Identity=35.1851851851852, Blast_Score=145, Evalue=5e-35,
Organism=Escherichia coli, GI87082123, Length=430, Percent_Identity=51.6279069767442, Blast_Score=423, Evalue=1e-119,
Organism=Escherichia coli, GI1790710, Length=250, Percent_Identity=41.2, Blast_Score=160, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17556903, Length=312, Percent_Identity=35.2564102564103, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17565172, Length=296, Percent_Identity=28.0405405405405, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221379063, Length=283, Percent_Identity=35.6890459363958, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI221379062, Length=283, Percent_Identity=35.6890459363958, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21357381, Length=290, Percent_Identity=35.8620689655172, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21355645, Length=324, Percent_Identity=28.3950617283951, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24662223, Length=324, Percent_Identity=28.3950617283951, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI20129969, Length=301, Percent_Identity=28.2392026578073, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24662227, Length=301, Percent_Identity=27.906976744186, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI21355725, Length=315, Percent_Identity=31.7460317460317, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI161077148, Length=287, Percent_Identity=29.9651567944251, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20130057, Length=287, Percent_Identity=29.9651567944251, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24661038, Length=315, Percent_Identity=30.7936507936508, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19922386, Length=300, Percent_Identity=26.6666666666667, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI20129963, Length=314, Percent_Identity=27.0700636942675, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24646701, Length=132, Percent_Identity=36.3636363636364, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646703, Length=132, Percent_Identity=36.3636363636364, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358201, Length=132, Percent_Identity=36.3636363636364, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008330
- InterPro:   IPR011356
- InterPro:   IPR000819 [H]

Pfam domain/function: PF00883 Peptidase_M17 [H]

EC number: =3.4.11.23 [H]

Molecular weight: Translated: 46140; Mature: 46009

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVFLVSLSFATASVIWGKGALLSFSEGHATIHLNKDNPLFRQVQAAARKLDGMSLEGI
CCCEEEEEEECCEEEEEECCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCE
KLDGSLWDKELRWAFSQGFYNAKKGANIDFSELDPAQLQNLTAQKKIVEWVRETINLGPE
EECCCHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
ALAPNVLCDKAVKLIESVLPEGIAISHKIIEGEDLLIENYQGIYQVGRGSTRPPCMLQLD
HHCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCCHHHHHCCCCCCCCEEEEEE
FNPTGDPDAAVDYALVGKGITFDSGGYSLKPSGSMAIMKSDMGGAATLTGALALAIVNGL
CCCCCCCCHHEEHEEECCCEEECCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHCC
NKRVKLYLCCAENLVSGHAYKLGDVITYKNGVTVEVLNSDAEGRLVLADGLIAAQEDNAG
CCEEEEEEEEHHHHHCCCCEECCCEEEECCCCEEEEECCCCCCEEEEECCEEEEECCCCE
IIIDAATLTGAAKMAVGRDYNCVLSMDDQLAELASRCAKQENEYLWRLPLEEFHFQQIGS
EEEEEHHHCCHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH
SFADIANIHSGEGMAGASTAAAFLANFVINPQSNWIHFDLSGSYQLSENGLWATGGKGHG
HHHHHHHCCCCCCCCCHHHHHHHHHHHEECCCCCEEEEECCCCEEECCCCEEEECCCCCC
VRTISKMLFA
HHHHHHHHCC
>Mature Secondary Structure 
SNVFLVSLSFATASVIWGKGALLSFSEGHATIHLNKDNPLFRQVQAAARKLDGMSLEGI
CCEEEEEEECCEEEEEECCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCE
KLDGSLWDKELRWAFSQGFYNAKKGANIDFSELDPAQLQNLTAQKKIVEWVRETINLGPE
EECCCHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
ALAPNVLCDKAVKLIESVLPEGIAISHKIIEGEDLLIENYQGIYQVGRGSTRPPCMLQLD
HHCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCCHHHHHCCCCCCCCEEEEEE
FNPTGDPDAAVDYALVGKGITFDSGGYSLKPSGSMAIMKSDMGGAATLTGALALAIVNGL
CCCCCCCCHHEEHEEECCCEEECCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHCC
NKRVKLYLCCAENLVSGHAYKLGDVITYKNGVTVEVLNSDAEGRLVLADGLIAAQEDNAG
CCEEEEEEEEHHHHHCCCCEECCCEEEECCCCEEEEECCCCCCEEEEECCEEEEECCCCE
IIIDAATLTGAAKMAVGRDYNCVLSMDDQLAELASRCAKQENEYLWRLPLEEFHFQQIGS
EEEEEHHHCCHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH
SFADIANIHSGEGMAGASTAAAFLANFVINPQSNWIHFDLSGSYQLSENGLWATGGKGHG
HHHHHHHCCCCCCCCCHHHHHHHHHHHEECCCCCEEEEECCCCEEECCCCEEEECCCCCC
VRTISKMLFA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA