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The map label for this gene is hscA [H]

Identifier: 119944981

GI number: 119944981

Start: 1533965

End: 1535896

Strand: Direct

Name: hscA [H]

Synonym: Ping_1232

Alternate gene names: 119944981

Gene position: 1533965-1535896 (Clockwise)

Preceding gene: 119944980

Following gene: 119944982

Centisome position: 33.64

GC content: 46.33

Gene sequence:

>1932_bases
ATGAACGAAACTATGCCAAACAACACACAATCTCGTTATTCCATTGGAATCGACTTAGGCACAACACACTGCGTATTATC
TTATATGGATCTCTCGAAGATAGCGGAAGATCCTGCATTAGTGCCGGAATTGATTATTATGCCTATTCCACAATTAACGC
AGGCAGGTATTATTGAAGAAAAAAAACAATTACCCTCTTTTATCTACATGGCCCATGAATCAGAGTTAAATGATGCTGAT
ATTGCCTTGCCTTGGAACGCTCAGCCGAATGCTATTGTTGGTAGTATTGCGCGTGAACTGGGCAGTAAAACAGCTATTCG
TTTAGTGTCAAGTGCAAAAAGCTGGTTGTGCCACAGTGGTGTTGATCGCCATGCGGCATTTTTACCTGCTGCCAGCCCCG
AAGAGGTCCGCAAAATATCACCCTTAGATGCCACCTTTGAATATTTAAATCATATGCGTGCTGCTTGGGATGATAAATTT
CCCGATTTTCCATTAGCGAAACAAGATGTGACTATCACTATTCCGGCTTCATTTGATCCCGCGGCAAGAGAGCTGACCGC
AGAAGCTGCCAAGCGAGTTGGTTTTGATAACCTGACCTTGTTAGAAGAGCCGCAGGCGGCTGTTTACAACTGGATCCACG
CCTGTGGAGAAGCTTGGCGTGAGCAGGTTCAGGTGGGTGATATTATTTTAGTGGTTGACGTTGGTGGTGGTACAACTGAT
CTATCATTAATTGCGGTAACCGAAGAAGAGGGTAACTTAACACTGAATCGTATTGCTGTCGGGGAACATATATTACTCGG
TGGCGATAATATGGATTTAGCCCTGGCTTACCGGGTTAAAGCTAAATTAAGCGCAGAGGGAAAAGAGTTACAGGCATGGC
AAATTCAAGCGATTAGTCAAGCCTGTCGGGATGCAAAAGAGCAACTTTTACTGGATAACGATATCAGCAGTGTGCCTATT
ACGGTACCGAGTCGTGGCTCAAAACTACTGGGTAAAACCCTGCGCACGGAGTTAACCCGCAATGAAGTTCGTGAGACATT
ACTGGAAGGTTTCTTCCCCGTTGTTAATATCAATGATCATCCCAAAGCAGCTCGCCGCAGTGGTTTAACACAAAAAGGCT
TGCCTTATGCGCAAGACCCGGCTGTTTCGCGTCATCTGGCGGCTTTTTTAAGCAAGCAGGTGAGTGCCGCTGATGATGTT
TTAGGCAGTACAAGTTTGCAAAGTAATAATGAGGATTTTGCAGATCCATTAGCAGGTAATTTTGATAAGGCTGATAGCGT
CGATTTTATTAAACCCTCGGCTATTTTATTTAATGGTGGTGTACTGAAATCGCCTCTGTTAGCAGAGCGGACTATGGCGA
CTATCAATCAGTGGCTGGAGGATGCGGGTGCTGAAAAAGCGCGATTATTAGCTGACTCTGACCTGGATCTTGCTGTTGCC
AGTGGTGCAAGTTATTACGGTTATGTTAAACGCGGGCAGGGTGTACGAATTCGCGGAGGCTTAGCTAATACTTATTATGT
CGGCATTGAAAGCTCGATGCCCGCTATTCCAGGTATGGAGCCTCCATTAGAAGCCTTGTGTATTGCACCTTTTGGGATGG
AAGAAGGCACTGAAACAGTGCCAAGTGAAGCTGAATTTGGGTTGGTTGTCGGCGAACCCGTGCGCTTCCGTTTTTTTGGA
TCAAACATCCGTCGTCATGATCAAGCAGGTCTGCAGCTCGAGCATTGGATCGATGATGAGTTACAAGAGCTGCCCGAATT
ACAAGCAACCTTATCGGTGGAAGGGCGCCGAGTGGGTGATGTTGTTCCGGTTCGTTTGCAGGCGAAAGTCACCGAAGTCG
GGACACTTCAACTTGAAGCTATCGCGGTTAACAGTCGCGAGACTAACGGCTCCCCAGAGCGCTGGCATATTGAACTGGAT
GTACGAGATTAA

Upstream 100 bases:

>100_bases
GCACGTTGATCCATAAAGGTTGGAAAGTGAGTGAGGTTAAGTTACCTAAATTAGCGGCGGGACACGATGCTTCAATCATT
GCACCTGCGGAGGTGGAATT

Downstream 100 bases:

>100_bases
TGAATAATCTTGTTGTTAAATATCTGATTGGTATCGATTTAGGCACCACCAATACCGTGGTTGCCTATACTGATATGCTT
AAGCCGTTAACCTCAGATAA

Product: chaperone DnaK-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MNETMPNNTQSRYSIGIDLGTTHCVLSYMDLSKIAEDPALVPELIIMPIPQLTQAGIIEEKKQLPSFIYMAHESELNDAD
IALPWNAQPNAIVGSIARELGSKTAIRLVSSAKSWLCHSGVDRHAAFLPAASPEEVRKISPLDATFEYLNHMRAAWDDKF
PDFPLAKQDVTITIPASFDPAARELTAEAAKRVGFDNLTLLEEPQAAVYNWIHACGEAWREQVQVGDIILVVDVGGGTTD
LSLIAVTEEEGNLTLNRIAVGEHILLGGDNMDLALAYRVKAKLSAEGKELQAWQIQAISQACRDAKEQLLLDNDISSVPI
TVPSRGSKLLGKTLRTELTRNEVRETLLEGFFPVVNINDHPKAARRSGLTQKGLPYAQDPAVSRHLAAFLSKQVSAADDV
LGSTSLQSNNEDFADPLAGNFDKADSVDFIKPSAILFNGGVLKSPLLAERTMATINQWLEDAGAEKARLLADSDLDLAVA
SGASYYGYVKRGQGVRIRGGLANTYYVGIESSMPAIPGMEPPLEALCIAPFGMEEGTETVPSEAEFGLVVGEPVRFRFFG
SNIRRHDQAGLQLEHWIDDELQELPELQATLSVEGRRVGDVVPVRLQAKVTEVGTLQLEAIAVNSRETNGSPERWHIELD
VRD

Sequences:

>Translated_643_residues
MNETMPNNTQSRYSIGIDLGTTHCVLSYMDLSKIAEDPALVPELIIMPIPQLTQAGIIEEKKQLPSFIYMAHESELNDAD
IALPWNAQPNAIVGSIARELGSKTAIRLVSSAKSWLCHSGVDRHAAFLPAASPEEVRKISPLDATFEYLNHMRAAWDDKF
PDFPLAKQDVTITIPASFDPAARELTAEAAKRVGFDNLTLLEEPQAAVYNWIHACGEAWREQVQVGDIILVVDVGGGTTD
LSLIAVTEEEGNLTLNRIAVGEHILLGGDNMDLALAYRVKAKLSAEGKELQAWQIQAISQACRDAKEQLLLDNDISSVPI
TVPSRGSKLLGKTLRTELTRNEVRETLLEGFFPVVNINDHPKAARRSGLTQKGLPYAQDPAVSRHLAAFLSKQVSAADDV
LGSTSLQSNNEDFADPLAGNFDKADSVDFIKPSAILFNGGVLKSPLLAERTMATINQWLEDAGAEKARLLADSDLDLAVA
SGASYYGYVKRGQGVRIRGGLANTYYVGIESSMPAIPGMEPPLEALCIAPFGMEEGTETVPSEAEFGLVVGEPVRFRFFG
SNIRRHDQAGLQLEHWIDDELQELPELQATLSVEGRRVGDVVPVRLQAKVTEVGTLQLEAIAVNSRETNGSPERWHIELD
VRD
>Mature_643_residues
MNETMPNNTQSRYSIGIDLGTTHCVLSYMDLSKIAEDPALVPELIIMPIPQLTQAGIIEEKKQLPSFIYMAHESELNDAD
IALPWNAQPNAIVGSIARELGSKTAIRLVSSAKSWLCHSGVDRHAAFLPAASPEEVRKISPLDATFEYLNHMRAAWDDKF
PDFPLAKQDVTITIPASFDPAARELTAEAAKRVGFDNLTLLEEPQAAVYNWIHACGEAWREQVQVGDIILVVDVGGGTTD
LSLIAVTEEEGNLTLNRIAVGEHILLGGDNMDLALAYRVKAKLSAEGKELQAWQIQAISQACRDAKEQLLLDNDISSVPI
TVPSRGSKLLGKTLRTELTRNEVRETLLEGFFPVVNINDHPKAARRSGLTQKGLPYAQDPAVSRHLAAFLSKQVSAADDV
LGSTSLQSNNEDFADPLAGNFDKADSVDFIKPSAILFNGGVLKSPLLAERTMATINQWLEDAGAEKARLLADSDLDLAVA
SGASYYGYVKRGQGVRIRGGLANTYYVGIESSMPAIPGMEPPLEALCIAPFGMEEGTETVPSEAEFGLVVGEPVRFRFFG
SNIRRHDQAGLQLEHWIDDELQELPELQATLSVEGRRVGDVVPVRLQAKVTEVGTLQLEAIAVNSRETNGSPERWHIELD
VRD

Specific function: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by hscB [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Escherichia coli, GI1786196, Length=336, Percent_Identity=25.297619047619, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI87082035, Length=305, Percent_Identity=23.9344262295082, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 320 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stati

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126
- InterPro:   IPR010236 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 70129; Mature: 70129

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00297 HSP70_1 ; PS00329 HSP70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETMPNNTQSRYSIGIDLGTTHCVLSYMDLSKIAEDPALVPELIIMPIPQLTQAGIIEE
CCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHCCHHHH
KKQLPSFIYMAHESELNDADIALPWNAQPNAIVGSIARELGSKTAIRLVSSAKSWLCHSG
HHHCCCEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
VDRHAAFLPAASPEEVRKISPLDATFEYLNHMRAAWDDKFPDFPLAKQDVTITIPASFDP
CCHHHEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCH
AARELTAEAAKRVGFDNLTLLEEPQAAVYNWIHACGEAWREQVQVGDIILVVDVGGGTTD
HHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
LSLIAVTEEEGNLTLNRIAVGEHILLGGDNMDLALAYRVKAKLSAEGKELQAWQIQAISQ
EEEEEEEECCCCEEEEEEEECCEEEECCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHH
ACRDAKEQLLLDNDISSVPITVPSRGSKLLGKTLRTELTRNEVRETLLEGFFPVVNINDH
HHHHHHHHEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
PKAARRSGLTQKGLPYAQDPAVSRHLAAFLSKQVSAADDVLGSTSLQSNNEDFADPLAGN
CCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCC
FDKADSVDFIKPSAILFNGGVLKSPLLAERTMATINQWLEDAGAEKARLLADSDLDLAVA
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEE
SGASYYGYVKRGQGVRIRGGLANTYYVGIESSMPAIPGMEPPLEALCIAPFGMEEGTETV
CCCCEEEEEECCCCEEEECCCCEEEEEEECCCCCCCCCCCCCHHHEEECCCCCCCCCCCC
PSEAEFGLVVGEPVRFRFFGSNIRRHDQAGLQLEHWIDDELQELPELQATLSVEGRRVGD
CCCCCCEEEECCCEEEEEECCCCCHHHHCCCCHHHHCCHHHHHHHHHHEEEEECCCCCCC
VVPVRLQAKVTEVGTLQLEAIAVNSRETNGSPERWHIELDVRD
EEEEEEEEEEEECCEEEEEEEEEECCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MNETMPNNTQSRYSIGIDLGTTHCVLSYMDLSKIAEDPALVPELIIMPIPQLTQAGIIEE
CCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHCCHHHH
KKQLPSFIYMAHESELNDADIALPWNAQPNAIVGSIARELGSKTAIRLVSSAKSWLCHSG
HHHCCCEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
VDRHAAFLPAASPEEVRKISPLDATFEYLNHMRAAWDDKFPDFPLAKQDVTITIPASFDP
CCHHHEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCH
AARELTAEAAKRVGFDNLTLLEEPQAAVYNWIHACGEAWREQVQVGDIILVVDVGGGTTD
HHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
LSLIAVTEEEGNLTLNRIAVGEHILLGGDNMDLALAYRVKAKLSAEGKELQAWQIQAISQ
EEEEEEEECCCCEEEEEEEECCEEEECCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHH
ACRDAKEQLLLDNDISSVPITVPSRGSKLLGKTLRTELTRNEVRETLLEGFFPVVNINDH
HHHHHHHHEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
PKAARRSGLTQKGLPYAQDPAVSRHLAAFLSKQVSAADDVLGSTSLQSNNEDFADPLAGN
CCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCC
FDKADSVDFIKPSAILFNGGVLKSPLLAERTMATINQWLEDAGAEKARLLADSDLDLAVA
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEE
SGASYYGYVKRGQGVRIRGGLANTYYVGIESSMPAIPGMEPPLEALCIAPFGMEEGTETV
CCCCEEEEEECCCCEEEECCCCEEEEEEECCCCCCCCCCCCCHHHEEECCCCCCCCCCCC
PSEAEFGLVVGEPVRFRFFGSNIRRHDQAGLQLEHWIDDELQELPELQATLSVEGRRVGD
CCCCCCEEEECCCEEEEEECCCCCHHHHCCCCHHHHCCHHHHHHHHHHEEEEECCCCCCC
VVPVRLQAKVTEVGTLQLEAIAVNSRETNGSPERWHIELDVRD
EEEEEEEEEEEECCEEEEEEEEEECCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA