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The map label for this gene is kefC [H]

Identifier: 119944863

GI number: 119944863

Start: 1379680

End: 1381341

Strand: Reverse

Name: kefC [H]

Synonym: Ping_1105

Alternate gene names: 119944863

Gene position: 1381341-1379680 (Counterclockwise)

Preceding gene: 119944864

Following gene: 119944862

Centisome position: 30.3

GC content: 38.45

Gene sequence:

>1662_bases
ATGTGTCATTGGCATTACTTCTCCCCTTTATCAAATGAGCTTCATATGGATTTTTCTATACTACTTTTTATTGGCACCGC
CTTCACCTTCGGTATGGTGGTTAACTTTACTAGCTTACCGCCAATGGTTGGGTTTTTAATAGCGGGTTTTGTCCTTAATT
TTTTCGGTTTTGAATCGAGTGAAGGGTTGGTTAGTCTGGCGAATTTAGGTGTCACCTTATTACTCTTTTCTATCGGATTA
AAATTAGATATCCGCACCCTCTTTAAAAGCGAAGTTTGGGGAGGTGCGAGTATTCATCTTATCGCCAGTATTATTTTTTA
TACCCTGCTGCTCTTGTCCTTAAAAGTGATTGGTTTAATCTTTTTTATTGATCTCAAAATAATGGAGTTAATACTTGTCT
CCTTTACATTAAGTTTTTCAAGTACCGTATTTGCGGTGAAAATTCTAGAAGAAAAAAGTGAAACAAACTCACTTTATGGC
AGGATAGCAATCGGTATTTTGATTATGCAGGATATTTTTGCTGTCCTGTTTTTAACCGTTTCGATCGGGGAAATGCCATC
AATTTGGGCCGTTGCATTATTAGGGTTACCCCTTATCCGCCCTCTTTTATTTAAACTATTAGATAGAGCAGGCCACGGCG
AATTATTAGTATTATATGGTTTCTTTTTAGCCTTGGTTGTCGGAGCAGGTTTATTTGAATTTGCCGGCTTAAAGGCAGAT
TTAGGCGCGCTAATCGCAGGAATGCTACTTGCGGGACACCCCAGTGCTAAAGATATGGCCAAATCTTTATTTAATTTGAA
AGAGCTGTTTTTAATCTGCTTCTTTTTGAGTATCGGCTTGGGTGGATTGCCAAATATTGATCATGTTATGGTTGCAGGCA
TTTTATCCATTTTGTTATTAGGAAAAATTACACTTTATTTCCTCACCTTAAGCCGATTTAAATTACGCTCACGGACTTCT
CTGTTCACTTCGTTTTCATTGGCAAATTATAGTGAATTTGGCTTAATTGTCGCCGCCCTTGCCACCCATAAAGGTTGGTT
ATCTCAAGATTGGTTGATTATCATCGCCATTGCCGTCTCGTTTAGCTTTATTATCGCCTCGTTATTGAATAAATTTTCGG
ATACTATCTACAGCCGCTTTAGCCATCCTTTAAAACGTTTTCAGGCAAAACGTTTACATAAAGATGATCGCCCGGTGCGG
GTGGGTGATGCACAAATATTAGTGTTAGGGATGGGTCAAATAGGGACAGGCGCCTATGAGGCGCTAAAAATAACCTACGG
TGAACGGGTAATGGGGATTGACTACAATCATCAAAAAACCCTAGATCATCGCGCCCATGGAAGACGGGTGATAACCGGTG
ATGCGTTAGATTCAGATTTTTGGAATAAATTACAACTAACAGATAATATTAAACTTATTTTATTAGCTATGCCGGATCAT
AATGGTAATCGTTATGCGGCAGAGCAACTTAATAAAATTAGCAGTGCCAATTTTAAAGTCGCAGCACTTGCCCATTATAA
AAGCGATCAAGCGGAATTAAATGAATTTGGTGTTAATCAAGTTTACAATATGTATGAGGAAGCAGGCTCTGGTTTTGCGC
GCCATGTTTGTTCTGAATTACAGATTTCATTGCTAAAAGATCACCATAAACAAGAGTTATAA

Upstream 100 bases:

>100_bases
TATTGTAAAATATTATAAAATCAATTTACCACCGTTTTTTATTAAAAGGTTTTAAATGCGCAGGAAAATATAATAAAAGC
AGCAATCAAGTTGAACCGCA

Downstream 100 bases:

>100_bases
TCATTCATTTGTCCAAATAGACTTATTTATAACTTATTACTGTGATTTAGTGTGACTTTTATTGATTATTCTGCAAAAAT
CGTCTATCAAATTATTGTTT

Product: glutathione-regulated potassium-efflux system protein KefC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MCHWHYFSPLSNELHMDFSILLFIGTAFTFGMVVNFTSLPPMVGFLIAGFVLNFFGFESSEGLVSLANLGVTLLLFSIGL
KLDIRTLFKSEVWGGASIHLIASIIFYTLLLLSLKVIGLIFFIDLKIMELILVSFTLSFSSTVFAVKILEEKSETNSLYG
RIAIGILIMQDIFAVLFLTVSIGEMPSIWAVALLGLPLIRPLLFKLLDRAGHGELLVLYGFFLALVVGAGLFEFAGLKAD
LGALIAGMLLAGHPSAKDMAKSLFNLKELFLICFFLSIGLGGLPNIDHVMVAGILSILLLGKITLYFLTLSRFKLRSRTS
LFTSFSLANYSEFGLIVAALATHKGWLSQDWLIIIAIAVSFSFIIASLLNKFSDTIYSRFSHPLKRFQAKRLHKDDRPVR
VGDAQILVLGMGQIGTGAYEALKITYGERVMGIDYNHQKTLDHRAHGRRVITGDALDSDFWNKLQLTDNIKLILLAMPDH
NGNRYAAEQLNKISSANFKVAALAHYKSDQAELNEFGVNQVYNMYEEAGSGFARHVCSELQISLLKDHHKQEL

Sequences:

>Translated_553_residues
MCHWHYFSPLSNELHMDFSILLFIGTAFTFGMVVNFTSLPPMVGFLIAGFVLNFFGFESSEGLVSLANLGVTLLLFSIGL
KLDIRTLFKSEVWGGASIHLIASIIFYTLLLLSLKVIGLIFFIDLKIMELILVSFTLSFSSTVFAVKILEEKSETNSLYG
RIAIGILIMQDIFAVLFLTVSIGEMPSIWAVALLGLPLIRPLLFKLLDRAGHGELLVLYGFFLALVVGAGLFEFAGLKAD
LGALIAGMLLAGHPSAKDMAKSLFNLKELFLICFFLSIGLGGLPNIDHVMVAGILSILLLGKITLYFLTLSRFKLRSRTS
LFTSFSLANYSEFGLIVAALATHKGWLSQDWLIIIAIAVSFSFIIASLLNKFSDTIYSRFSHPLKRFQAKRLHKDDRPVR
VGDAQILVLGMGQIGTGAYEALKITYGERVMGIDYNHQKTLDHRAHGRRVITGDALDSDFWNKLQLTDNIKLILLAMPDH
NGNRYAAEQLNKISSANFKVAALAHYKSDQAELNEFGVNQVYNMYEEAGSGFARHVCSELQISLLKDHHKQEL
>Mature_553_residues
MCHWHYFSPLSNELHMDFSILLFIGTAFTFGMVVNFTSLPPMVGFLIAGFVLNFFGFESSEGLVSLANLGVTLLLFSIGL
KLDIRTLFKSEVWGGASIHLIASIIFYTLLLLSLKVIGLIFFIDLKIMELILVSFTLSFSSTVFAVKILEEKSETNSLYG
RIAIGILIMQDIFAVLFLTVSIGEMPSIWAVALLGLPLIRPLLFKLLDRAGHGELLVLYGFFLALVVGAGLFEFAGLKAD
LGALIAGMLLAGHPSAKDMAKSLFNLKELFLICFFLSIGLGGLPNIDHVMVAGILSILLLGKITLYFLTLSRFKLRSRTS
LFTSFSLANYSEFGLIVAALATHKGWLSQDWLIIIAIAVSFSFIIASLLNKFSDTIYSRFSHPLKRFQAKRLHKDDRPVR
VGDAQILVLGMGQIGTGAYEALKITYGERVMGIDYNHQKTLDHRAHGRRVITGDALDSDFWNKLQLTDNIKLILLAMPDH
NGNRYAAEQLNKISSANFKVAALAHYKSDQAELNEFGVNQVYNMYEEAGSGFARHVCSELQISLLKDHHKQEL

Specific function: Unknown

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1786685, Length=531, Percent_Identity=27.3069679849341, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786232, Length=486, Percent_Identity=26.9547325102881, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789749, Length=475, Percent_Identity=25.4736842105263, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 61338; Mature: 61338

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00014 ER_TARGET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCHWHYFSPLSNELHMDFSILLFIGTAFTFGMVVNFTSLPPMVGFLIAGFVLNFFGFESS
CCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
EGLVSLANLGVTLLLFSIGLKLDIRTLFKSEVWGGASIHLIASIIFYTLLLLSLKVIGLI
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FFIDLKIMELILVSFTLSFSSTVFAVKILEEKSETNSLYGRIAIGILIMQDIFAVLFLTV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIGEMPSIWAVALLGLPLIRPLLFKLLDRAGHGELLVLYGFFLALVVGAGLFEFAGLKAD
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHCCCHHH
LGALIAGMLLAGHPSAKDMAKSLFNLKELFLICFFLSIGLGGLPNIDHVMVAGILSILLL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GKITLYFLTLSRFKLRSRTSLFTSFSLANYSEFGLIVAALATHKGWLSQDWLIIIAIAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FSFIIASLLNKFSDTIYSRFSHPLKRFQAKRLHKDDRPVRVGDAQILVLGMGQIGTGAYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCHHH
ALKITYGERVMGIDYNHQKTLDHRAHGRRVITGDALDSDFWNKLQLTDNIKLILLAMPDH
HEEEEECCEEEECCCCCHHHHHHHHCCCEEEECCCCCCHHHCCEEECCCEEEEEEEECCC
NGNRYAAEQLNKISSANFKVAALAHYKSDQAELNEFGVNQVYNMYEEAGSGFARHVCSEL
CCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
QISLLKDHHKQEL
HHHHHHHHHHCCC
>Mature Secondary Structure
MCHWHYFSPLSNELHMDFSILLFIGTAFTFGMVVNFTSLPPMVGFLIAGFVLNFFGFESS
CCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
EGLVSLANLGVTLLLFSIGLKLDIRTLFKSEVWGGASIHLIASIIFYTLLLLSLKVIGLI
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FFIDLKIMELILVSFTLSFSSTVFAVKILEEKSETNSLYGRIAIGILIMQDIFAVLFLTV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIGEMPSIWAVALLGLPLIRPLLFKLLDRAGHGELLVLYGFFLALVVGAGLFEFAGLKAD
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHCCCHHH
LGALIAGMLLAGHPSAKDMAKSLFNLKELFLICFFLSIGLGGLPNIDHVMVAGILSILLL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GKITLYFLTLSRFKLRSRTSLFTSFSLANYSEFGLIVAALATHKGWLSQDWLIIIAIAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FSFIIASLLNKFSDTIYSRFSHPLKRFQAKRLHKDDRPVRVGDAQILVLGMGQIGTGAYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCHHH
ALKITYGERVMGIDYNHQKTLDHRAHGRRVITGDALDSDFWNKLQLTDNIKLILLAMPDH
HEEEEECCEEEECCCCCHHHHHHHHCCCEEEECCCCCCHHHCCEEECCCEEEEEEEECCC
NGNRYAAEQLNKISSANFKVAALAHYKSDQAELNEFGVNQVYNMYEEAGSGFARHVCSEL
CCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
QISLLKDHHKQEL
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]