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The map label for this gene is nadA [H]

Identifier: 119944501

GI number: 119944501

Start: 924102

End: 925163

Strand: Direct

Name: nadA [H]

Synonym: Ping_0730

Alternate gene names: 119944501

Gene position: 924102-925163 (Clockwise)

Preceding gene: 119944500

Following gene: 119944502

Centisome position: 20.27

GC content: 43.79

Gene sequence:

>1062_bases
ATGATGAGTAAATACTCTCCAATTGTGGGTTCAGACTATCCTTTTCCAGCTAAACCAGCGGTTCTTTCTGTACCTGAAAA
GGTTAATTATAAGGCTAGAATTAAAACGCTATTAAAAGAAAAAAATGCTGTTTTAATTGCACACTATTATACCGATCCCG
ACATTCAGGCATTAGCTGAAGAAACGGGCGGTTATGTTTCTGATTCATTAGATATGGCGCGTTTTGGTCGTGATAATCCA
GCCACTACACTGGTGGTTGCTGGCGTTCGCTTTATGGGGGAAACGGCTAAGATTTTAACACCCAATAAACAAGTGTTAAT
GCCTGAATTAGAGGCTACCTGCTCTTTAGATGTGGGCTGCCCAATCGAATCCTTCAGTGAGTTTTGTGATCAGCACCCGG
ACCGTACTGTGGTTGTTTATGCAAATACTTCAGCGGCTGTTAAGGCGCGTGCTGATTGGGTTGTGACTTCAAGTATTGCA
TTAGAAATTGTCGATCACCTTGATAGCCAGGGTAAGAAAATAATTTGGGGGCCGGACAGGCATTTAGGCGATTACATTCA
GCGCAAAACCAATGCTGATATGCTGATGTGGCAAGGTGACTGTATTGTTCATGACGAATTTAAAGCCAGTTCATTAAGGG
ACATGAAAGCGATTTATCCCGATGCCGCTATTTTAGTTCATCCGGAGTCGCCAGAGAGTGTGGTTAAATTGGCGGATGCG
GTAGGCTCAACAAGTCAGTTAATAAAAGCGGCGCAAACGTTACCTAACAAAACACTGATCGTTGCAACTGATACCGGCAT
TTTCTATAAAATGCAGCAGGCCTGTCCAGACAAAGAGTTTCTGGCAGCGCCAACTTCTGGCGACGGAGCAACCTGTCGGA
GTTGTGCACACTGTCCCTGGATGGCAATGAATGGTCTTAAGGCCGTATACAACGCCCTGAATGATGCGACTGGTCATGAA
ATTTATGTTGATGAAAAAGTTGCTCAAGGCGCATTAGTTTCTTTAGATAGAATGATGAACTTTGCCGCAGAGGCGCAGTT
AACAGTAAAAGGTAATGCATAA

Upstream 100 bases:

>100_bases
TAAATATAAAATTGATGGATTGGATATAAGCATTTTTTATTATCATTTTTACTGTTCTTCGCGGTACAATGACCAACATA
TTTTTAATATCTAAGAGACT

Downstream 100 bases:

>100_bases
TCTTATAAGGTTATTGCGAAGTTAACGCGCTTTCTTTTTCCATAATAATTCTAAATTGGCATATTTTCGCTGTTTGCGTA
TAGTGTGCCTTCTAAAAACC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MMSKYSPIVGSDYPFPAKPAVLSVPEKVNYKARIKTLLKEKNAVLIAHYYTDPDIQALAEETGGYVSDSLDMARFGRDNP
ATTLVVAGVRFMGETAKILTPNKQVLMPELEATCSLDVGCPIESFSEFCDQHPDRTVVVYANTSAAVKARADWVVTSSIA
LEIVDHLDSQGKKIIWGPDRHLGDYIQRKTNADMLMWQGDCIVHDEFKASSLRDMKAIYPDAAILVHPESPESVVKLADA
VGSTSQLIKAAQTLPNKTLIVATDTGIFYKMQQACPDKEFLAAPTSGDGATCRSCAHCPWMAMNGLKAVYNALNDATGHE
IYVDEKVAQGALVSLDRMMNFAAEAQLTVKGNA

Sequences:

>Translated_353_residues
MMSKYSPIVGSDYPFPAKPAVLSVPEKVNYKARIKTLLKEKNAVLIAHYYTDPDIQALAEETGGYVSDSLDMARFGRDNP
ATTLVVAGVRFMGETAKILTPNKQVLMPELEATCSLDVGCPIESFSEFCDQHPDRTVVVYANTSAAVKARADWVVTSSIA
LEIVDHLDSQGKKIIWGPDRHLGDYIQRKTNADMLMWQGDCIVHDEFKASSLRDMKAIYPDAAILVHPESPESVVKLADA
VGSTSQLIKAAQTLPNKTLIVATDTGIFYKMQQACPDKEFLAAPTSGDGATCRSCAHCPWMAMNGLKAVYNALNDATGHE
IYVDEKVAQGALVSLDRMMNFAAEAQLTVKGNA
>Mature_353_residues
MMSKYSPIVGSDYPFPAKPAVLSVPEKVNYKARIKTLLKEKNAVLIAHYYTDPDIQALAEETGGYVSDSLDMARFGRDNP
ATTLVVAGVRFMGETAKILTPNKQVLMPELEATCSLDVGCPIESFSEFCDQHPDRTVVVYANTSAAVKARADWVVTSSIA
LEIVDHLDSQGKKIIWGPDRHLGDYIQRKTNADMLMWQGDCIVHDEFKASSLRDMKAIYPDAAILVHPESPESVVKLADA
VGSTSQLIKAAQTLPNKTLIVATDTGIFYKMQQACPDKEFLAAPTSGDGATCRSCAHCPWMAMNGLKAVYNALNDATGHE
IYVDEKVAQGALVSLDRMMNFAAEAQLTVKGNA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=340, Percent_Identity=69.1176470588235, Blast_Score=512, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38425; Mature: 38425

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSKYSPIVGSDYPFPAKPAVLSVPEKVNYKARIKTLLKEKNAVLIAHYYTDPDIQALAE
CCCCCCCCCCCCCCCCCCCCEEECCHHCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHH
ETGGYVSDSLDMARFGRDNPATTLVVAGVRFMGETAKILTPNKQVLMPELEATCSLDVGC
HHCCCCCCCHHHHHCCCCCCCCEEEEEHHHHCCCCCEEECCCCCEECCCCCCEEEECCCC
PIESFSEFCDQHPDRTVVVYANTSAAVKARADWVVTSSIALEIVDHLDSQGKKIIWGPDR
CHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHHHHCCCCCEEEECCCH
HLGDYIQRKTNADMLMWQGDCIVHDEFKASSLRDMKAIYPDAAILVHPESPESVVKLADA
HHHHHHHHCCCCCEEEEECCEEEECCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHH
VGSTSQLIKAAQTLPNKTLIVATDTGIFYKMQQACPDKEFLAAPTSGDGATCRSCAHCPW
CCCHHHHHHHHHHCCCCEEEEEECCCCEEEHHHHCCCHHEEECCCCCCCHHHHHHCCCCH
MAMNGLKAVYNALNDATGHEIYVDEKVAQGALVSLDRMMNFAAEAQLTVKGNA
HHHHHHHHHHHHHCCCCCCEEEEECHHHCCHHHHHHHHHHHHHCEEEEEECCC
>Mature Secondary Structure
MMSKYSPIVGSDYPFPAKPAVLSVPEKVNYKARIKTLLKEKNAVLIAHYYTDPDIQALAE
CCCCCCCCCCCCCCCCCCCCEEECCHHCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHH
ETGGYVSDSLDMARFGRDNPATTLVVAGVRFMGETAKILTPNKQVLMPELEATCSLDVGC
HHCCCCCCCHHHHHCCCCCCCCEEEEEHHHHCCCCCEEECCCCCEECCCCCCEEEECCCC
PIESFSEFCDQHPDRTVVVYANTSAAVKARADWVVTSSIALEIVDHLDSQGKKIIWGPDR
CHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHHHHCCCCCEEEECCCH
HLGDYIQRKTNADMLMWQGDCIVHDEFKASSLRDMKAIYPDAAILVHPESPESVVKLADA
HHHHHHHHCCCCCEEEEECCEEEECCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHH
VGSTSQLIKAAQTLPNKTLIVATDTGIFYKMQQACPDKEFLAAPTSGDGATCRSCAHCPW
CCCHHHHHHHHHHCCCCEEEEEECCCCEEEHHHHCCCHHEEECCCCCCCHHHHHHCCCCH
MAMNGLKAVYNALNDATGHEIYVDEKVAQGALVSLDRMMNFAAEAQLTVKGNA
HHHHHHHHHHHHHCCCCCCEEEEECHHHCCHHHHHHHHHHHHHCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]