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The map label for this gene is ftsY [H]

Identifier: 119944395

GI number: 119944395

Start: 804020

End: 805381

Strand: Direct

Name: ftsY [H]

Synonym: Ping_0623

Alternate gene names: 119944395

Gene position: 804020-805381 (Clockwise)

Preceding gene: 119944392

Following gene: 119944396

Centisome position: 17.63

GC content: 41.12

Gene sequence:

>1362_bases
ATGACAAAAAAGAAAGGTCTATTTTCCTGGTTCGGAAAAAAATCAACTGAAGAAACAGAGCAAGCTGAAAAAAATGCATT
ACTTGAGGCGGATAAGCTCGAAGCTCAAAGGTTAGAAGCTGAGCAGCTCAAAGATCTAAAGCTTAAAGCCAAAAGGCTGG
AAGCTGAAAGGCTTGAAGCTGAAAAGCTTGAAGCTGAAAGGCTTGAAGCTGAAAGGCTTGAAGCTGAAAGGCTTGAAGCT
GAAAAGCTCGCAGCTCAAAGGCTTGAAGCTGAAAAGCTTGAAGCTGAAAAGCTTGAAGCTGAAAGGCTTGAAGCTGAAAG
GCTTGAAGCTGAAAGGCTTGAAACTGAAAAGCTCACAGCTCAACAGCTCGAAGCTCAACAGCCCACAGCCCCGCTCCCCT
CCAGTGAAAAACAAAAAACGGAAGAAAAAGCCCTCGGTTTTTTCGCGCGGTTCAAGCAAAGTTTGACCAAAACTCGTTTA
AGTATCGGCAGTGGTTTATATTCTTTATTTAGCGGTAAAAAAATTGACGCGGATCTTTTTGAAGAGTTGGAAGAGCAATT
AATCCTTGCCGATATTGGTGTTGATACAACATTAAAAATTATCGACAAATTAACCGCACAAGCGAATCGTAAACAACTTA
AAGATGCAGAAGCATTATATACCCTATTAAAAGAGGATCTTTCCGGCATATTGCAAGAAGTTGAACAGCCTTTAGTCATA
GATGAAACTAAATCGCCCTACGTTATCTTGATGGTCGGTGTTAATGGGGTAGGTAAAACGACCACTATTGGTAAATTGGC
TAAAAAATATCAACAACAGGGGAAATCGGTAATGTTAGCCGCAGGTGATACTTTTCGTGCTGCCGCCGTTGAACAATTAC
AGGTCTGGGGAGAGCGAAACAATATTCCCGTTATTGCGCAGCAAACAGGATCCGATAGTGCATCGGTATTGTTTGATGCA
ATGGATGCGGCTAAAGCACGAGGTATTGATGTGTTAATCGCAGATACTGCCGGTCGTTTACAAAATAAAGAGCATTTGAT
GGATGAGCTAAGCAAAGTGGTTCGTATTATGCGTAAAAAAGATCCCAGTGCACCCCATGAAATTATGCTAACCATTGATG
CAAGTACTGGCCAAAATGCCATAAGCCAGGCCGATTTATTTAATAAAGCAGTCGGAATTACCGGTATAACCTTAACCAAA
CTGGATGGCACAGCAAAAGGAGGGGTTATTTTTTCAATTGCTGATAAGTATAAACTGCCTATTCGTTATATTGGAACAGG
CGAAGGAATTGATGACTTAAGAGAATTTAATGCCAGGGAGTTTATTGACGCCCTTTTTTCGAAAGAAGAAGAGATTGAAT
AA

Upstream 100 bases:

>100_bases
GCTATAAACGACTGTGAAAAGTTTATTTCAGTGGTTTAAGCGTTTTTAATATGCTGCTATTTTAGCAGCCTAAATTGGTT
GTGAGTAAGGTTTTTAATTA

Downstream 100 bases:

>100_bases
GGTAACAAATAATTATGATTTTATTTGAAGACGTCAGCAAAGTCTATCCGCAGGACTATATTGCACTTAACCAGGTGGAT
TTTCATTTAAAACAGGGGGA

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MTKKKGLFSWFGKKSTEETEQAEKNALLEADKLEAQRLEAEQLKDLKLKAKRLEAERLEAEKLEAERLEAERLEAERLEA
EKLAAQRLEAEKLEAEKLEAERLEAERLEAERLETEKLTAQQLEAQQPTAPLPSSEKQKTEEKALGFFARFKQSLTKTRL
SIGSGLYSLFSGKKIDADLFEELEEQLILADIGVDTTLKIIDKLTAQANRKQLKDAEALYTLLKEDLSGILQEVEQPLVI
DETKSPYVILMVGVNGVGKTTTIGKLAKKYQQQGKSVMLAAGDTFRAAAVEQLQVWGERNNIPVIAQQTGSDSASVLFDA
MDAAKARGIDVLIADTAGRLQNKEHLMDELSKVVRIMRKKDPSAPHEIMLTIDASTGQNAISQADLFNKAVGITGITLTK
LDGTAKGGVIFSIADKYKLPIRYIGTGEGIDDLREFNAREFIDALFSKEEEIE

Sequences:

>Translated_453_residues
MTKKKGLFSWFGKKSTEETEQAEKNALLEADKLEAQRLEAEQLKDLKLKAKRLEAERLEAEKLEAERLEAERLEAERLEA
EKLAAQRLEAEKLEAEKLEAERLEAERLEAERLETEKLTAQQLEAQQPTAPLPSSEKQKTEEKALGFFARFKQSLTKTRL
SIGSGLYSLFSGKKIDADLFEELEEQLILADIGVDTTLKIIDKLTAQANRKQLKDAEALYTLLKEDLSGILQEVEQPLVI
DETKSPYVILMVGVNGVGKTTTIGKLAKKYQQQGKSVMLAAGDTFRAAAVEQLQVWGERNNIPVIAQQTGSDSASVLFDA
MDAAKARGIDVLIADTAGRLQNKEHLMDELSKVVRIMRKKDPSAPHEIMLTIDASTGQNAISQADLFNKAVGITGITLTK
LDGTAKGGVIFSIADKYKLPIRYIGTGEGIDDLREFNAREFIDALFSKEEEIE
>Mature_452_residues
TKKKGLFSWFGKKSTEETEQAEKNALLEADKLEAQRLEAEQLKDLKLKAKRLEAERLEAEKLEAERLEAERLEAERLEAE
KLAAQRLEAEKLEAEKLEAERLEAERLEAERLETEKLTAQQLEAQQPTAPLPSSEKQKTEEKALGFFARFKQSLTKTRLS
IGSGLYSLFSGKKIDADLFEELEEQLILADIGVDTTLKIIDKLTAQANRKQLKDAEALYTLLKEDLSGILQEVEQPLVID
ETKSPYVILMVGVNGVGKTTTIGKLAKKYQQQGKSVMLAAGDTFRAAAVEQLQVWGERNNIPVIAQQTGSDSASVLFDAM
DAAKARGIDVLIADTAGRLQNKEHLMDELSKVVRIMRKKDPSAPHEIMLTIDASTGQNAISQADLFNKAVGITGITLTKL
DGTAKGGVIFSIADKYKLPIRYIGTGEGIDDLREFNAREFIDALFSKEEEIE

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=200, Percent_Identity=37, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI226371618, Length=198, Percent_Identity=37.3737373737374, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI23308697, Length=302, Percent_Identity=28.8079470198675, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI295424842, Length=302, Percent_Identity=28.8079470198675, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI89061728, Length=121, Percent_Identity=37.1900826446281, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1789874, Length=327, Percent_Identity=70.6422018348624, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI1788963, Length=265, Percent_Identity=32.0754716981132, Blast_Score=139, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI193206261, Length=319, Percent_Identity=30.0940438871473, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17539958, Length=217, Percent_Identity=31.7972350230415, Blast_Score=122, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6325345, Length=199, Percent_Identity=36.6834170854271, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6320498, Length=324, Percent_Identity=26.8518518518519, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17647949, Length=297, Percent_Identity=30.3030303030303, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24641198, Length=324, Percent_Identity=29.6296296296296, Blast_Score=126, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 50338; Mature: 50207

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKKGLFSWFGKKSTEETEQAEKNALLEADKLEAQRLEAEQLKDLKLKAKRLEAERLEA
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKLEAERLEAERLEAERLEAEKLAAQRLEAEKLEAEKLEAERLEAERLEAERLETEKLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQLEAQQPTAPLPSSEKQKTEEKALGFFARFKQSLTKTRLSIGSGLYSLFSGKKIDADLF
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
EELEEQLILADIGVDTTLKIIDKLTAQANRKQLKDAEALYTLLKEDLSGILQEVEQPLVI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
DETKSPYVILMVGVNGVGKTTTIGKLAKKYQQQGKSVMLAAGDTFRAAAVEQLQVWGERN
ECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCC
NIPVIAQQTGSDSASVLFDAMDAAKARGIDVLIADTAGRLQNKEHLMDELSKVVRIMRKK
CCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHC
DPSAPHEIMLTIDASTGQNAISQADLFNKAVGITGITLTKLDGTAKGGVIFSIADKYKLP
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCC
IRYIGTGEGIDDLREFNAREFIDALFSKEEEIE
EEEEECCCCHHHHHHCCHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
TKKKGLFSWFGKKSTEETEQAEKNALLEADKLEAQRLEAEQLKDLKLKAKRLEAERLEA
CCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKLEAERLEAERLEAERLEAEKLAAQRLEAEKLEAEKLEAERLEAERLEAERLETEKLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQLEAQQPTAPLPSSEKQKTEEKALGFFARFKQSLTKTRLSIGSGLYSLFSGKKIDADLF
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
EELEEQLILADIGVDTTLKIIDKLTAQANRKQLKDAEALYTLLKEDLSGILQEVEQPLVI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
DETKSPYVILMVGVNGVGKTTTIGKLAKKYQQQGKSVMLAAGDTFRAAAVEQLQVWGERN
ECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCC
NIPVIAQQTGSDSASVLFDAMDAAKARGIDVLIADTAGRLQNKEHLMDELSKVVRIMRKK
CCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHC
DPSAPHEIMLTIDASTGQNAISQADLFNKAVGITGITLTKLDGTAKGGVIFSIADKYKLP
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCC
IRYIGTGEGIDDLREFNAREFIDALFSKEEEIE
EEEEECCCCHHHHHHCCHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]