Click here to switch to the map view.

The map label for this gene is rhtB [H]

Identifier: 119944366

GI number: 119944366

Start: 774701

End: 775333

Strand: Direct

Name: rhtB [H]

Synonym: Ping_0593

Alternate gene names: 119944366

Gene position: 774701-775333 (Clockwise)

Preceding gene: 119944365

Following gene: 119944367

Centisome position: 16.99

GC content: 36.02

Gene sequence:

>633_bases
ATGTCATTAGAATTATGGTTAACGTTTGCATTGGCATGTGTGATTTTTAGTATTGCTCCCGGTGCAGGTATGGTCACAAC
GGTCAGTAACTCAATTTCTGGGGGCTTTAAAACTGCAGTAAAGAATATATTAGGTTTACAGATAGCATTGTTGACCCATA
TTTTAATTGTATCAGCGGGACTCGGCGCGCTGTTAGCCACTTCTGCATTGGCTTTTACAATATTAAAATATCTTGGGGCC
GCTTATTTATTATATTTAGGCTTCTCTAAATTTTTCAGTTGTGAGGGGCCAGTAAATTCTGAATATGAATTAGTATCTAA
TGTATCCAATAAAAATCTAATATGGAAAGGCTTCGCTGCCAATATGATGAATCCTAAATCGATTGTATTTTTAGCGGCTT
TCTTACCGCAATTTTTAAATCCTGCACTTGACCTGGTTGTTCAATATATTGCATTAGGGAGTACGGTGCTAATGATCGAT
TTAGCCGTTATGTGCAGTTATGCTTTATTAGCGACCTTATTGAAACCCTATTTAGTTAAATCCAATTTTGTAAAATTACA
AAACAAAGTTTTTGGTTCATTGTTTATTGCAATGGGAATATTCTTGGCGAGAGTCGAGCAATCAACCAGCTAA

Upstream 100 bases:

>100_bases
CGCATAACAGCGGTCATTTTTTACAAAAGCTAAAACAGTTTACTCGCCGGTAAGCAGAGCATTAGCTATCAGTATTTATC
AATATAAAAAGGAATTCAGT

Downstream 100 bases:

>100_bases
TAAGTCAATCTACAAAAATATAATATTATCCGGGCATTATATTCCATAGGAAAGACTCGTGACAGCACAAGAATGCTGGC
TTGGTACTGTCAAATACCCC

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MSLELWLTFALACVIFSIAPGAGMVTTVSNSISGGFKTAVKNILGLQIALLTHILIVSAGLGALLATSALAFTILKYLGA
AYLLYLGFSKFFSCEGPVNSEYELVSNVSNKNLIWKGFAANMMNPKSIVFLAAFLPQFLNPALDLVVQYIALGSTVLMID
LAVMCSYALLATLLKPYLVKSNFVKLQNKVFGSLFIAMGIFLARVEQSTS

Sequences:

>Translated_210_residues
MSLELWLTFALACVIFSIAPGAGMVTTVSNSISGGFKTAVKNILGLQIALLTHILIVSAGLGALLATSALAFTILKYLGA
AYLLYLGFSKFFSCEGPVNSEYELVSNVSNKNLIWKGFAANMMNPKSIVFLAAFLPQFLNPALDLVVQYIALGSTVLMID
LAVMCSYALLATLLKPYLVKSNFVKLQNKVFGSLFIAMGIFLARVEQSTS
>Mature_209_residues
SLELWLTFALACVIFSIAPGAGMVTTVSNSISGGFKTAVKNILGLQIALLTHILIVSAGLGALLATSALAFTILKYLGAA
YLLYLGFSKFFSCEGPVNSEYELVSNVSNKNLIWKGFAANMMNPKSIVFLAAFLPQFLNPALDLVVQYIALGSTVLMIDL
AVMCSYALLATLLKPYLVKSNFVKLQNKVFGSLFIAMGIFLARVEQSTS

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=208, Percent_Identity=39.9038461538462, Blast_Score=160, Evalue=4e-41,
Organism=Escherichia coli, GI1788099, Length=208, Percent_Identity=25.4807692307692, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22539; Mature: 22408

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLELWLTFALACVIFSIAPGAGMVTTVSNSISGGFKTAVKNILGLQIALLTHILIVSAG
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGALLATSALAFTILKYLGAAYLLYLGFSKFFSCEGPVNSEYELVSNVSNKNLIWKGFAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEECHHH
NMMNPKSIVFLAAFLPQFLNPALDLVVQYIALGSTVLMIDLAVMCSYALLATLLKPYLVK
CCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNFVKLQNKVFGSLFIAMGIFLARVEQSTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLELWLTFALACVIFSIAPGAGMVTTVSNSISGGFKTAVKNILGLQIALLTHILIVSAG
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGALLATSALAFTILKYLGAAYLLYLGFSKFFSCEGPVNSEYELVSNVSNKNLIWKGFAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEECHHH
NMMNPKSIVFLAAFLPQFLNPALDLVVQYIALGSTVLMIDLAVMCSYALLATLLKPYLVK
CCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNFVKLQNKVFGSLFIAMGIFLARVEQSTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]