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The map label for this gene is siaT [H]

Identifier: 119944345

GI number: 119944345

Start: 751679

End: 752998

Strand: Direct

Name: siaT [H]

Synonym: Ping_0572

Alternate gene names: 119944345

Gene position: 751679-752998 (Clockwise)

Preceding gene: 119944344

Following gene: 119944346

Centisome position: 16.49

GC content: 42.65

Gene sequence:

>1320_bases
ATGGAAATTGAATTATTAACGGGCATTTTATTGCTCTGTATTTTAGTGGCCTTTGCCTTAGGTGCTCAGGTTGGACTTGC
ATTGGCGGGGATCGCCATGGGGGTTGGTTATTTAGTATGGGGTGAGGCATTATTTAATGTTATTCCAAGCACGGTTGAAG
GTACCTTTTTTAACTTTATTCTGCTTGCCATTCCCCTGTATATTTATATGGGACAGATTCTGACTCGCTCGGGTATTGGT
GATGCGATGTTTAATGCCAGTCAATTAGTGATTGGGCGACTGCGCGGATCGCTTGCAATCAGTGTGATTGGGGTTTGTTC
TATGATTGGCGCGATGGTGGGTATTATTGGTGCGGGTATTATGACCTCCAGCAGTATTGCACTTCAGCCGATGTTAGATC
GTGGTTATGATAAACGACTCGCACTAGGCGTTATTATGGCGGGGGGATCTCTCGGTATTCTCATTCCGCCCAGTATCCCG
ATGATTATGTTTGCGGCTGCCACCCAAAACTCTGTTGGGAGGATGTTTTTAGCGGCGATGGTGCCGGCATTAATTACGAT
TGTTTTACTCATTAGTTATGTGCTTATTACCTGTAAGTTAAATCCTGAGAAAGCACCGCTTGATAAAGAGAATGATATTC
AAATCCCCAAAGGTTACGAGTTATTTAGAACTATTCGTGATGGTTTCTCTTCACTGCTGCTGATTGTCGCGGTACTCGGC
AGTATTATTATCGGCATTGCCACGCCAACAGAATCGGGTGCCATCGGGGTAGTCGGTGCGATTATTCTGGCGATACTCTT
TAAACGTTTTAAACCTGCCATTATGATTAAAGCCGGCTTGCAGACTTCAATTTTAGTGAGTGTCGCAATGTGGATTATTT
TAGGCGCTTCTGTATTTAGTAATTTCCATCTTCTGATGGGGGTACAAACTATGGTGGCAGGGTTTGCAACCAGCTTAGAT
TTACCGCCAATCTACATTATTATTATGTTTCAACTCATTATGCTGCTGCTTGGCTTTATTATTGATGAGTTTATTATTGT
CTTAATGTGTGCGCCTATCTTTACCCCAATCGCCGTTTCTTTGGGTTATGACCCGATCTGGTTTGGTGTGTTAATGATTT
TAAATATAGTGATTGCGGTGCAGACACCACCCTACGGATTTGCACTGTTTTATTTAAAAGGCATTGCACCTAAAGGTATT
ACTATGATGGATATTTATAAATCGGTAACGCCATTTATTCTGGTACAGTTAGTCGTGCTGATTATCTGCATGGTCTTTCC
CGAGTTAGTGCTGTGGTTACCGAACAAGATGATGGACTGA

Upstream 100 bases:

>100_bases
AAAATCAGCAGTCAGTAAGAGTCTGTAACAGAACTATCTGTCTGCAGATTATTTGAATAACGAATATTACGCGATAAAAA
TAAAGAAGTAGGATACTCAG

Downstream 100 bases:

>100_bases
CAATAGATAATAGAAAATGTAATAAAGACAAAAAAGGGCTCCACTAAAGCAAGATAATTGCCTTATTGGAGCCCTTGCTG
CTCAGATCTTCATCCAGACA

Product: TRAP dicarboxylate transporter, DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MEIELLTGILLLCILVAFALGAQVGLALAGIAMGVGYLVWGEALFNVIPSTVEGTFFNFILLAIPLYIYMGQILTRSGIG
DAMFNASQLVIGRLRGSLAISVIGVCSMIGAMVGIIGAGIMTSSSIALQPMLDRGYDKRLALGVIMAGGSLGILIPPSIP
MIMFAAATQNSVGRMFLAAMVPALITIVLLISYVLITCKLNPEKAPLDKENDIQIPKGYELFRTIRDGFSSLLLIVAVLG
SIIIGIATPTESGAIGVVGAIILAILFKRFKPAIMIKAGLQTSILVSVAMWIILGASVFSNFHLLMGVQTMVAGFATSLD
LPPIYIIIMFQLIMLLLGFIIDEFIIVLMCAPIFTPIAVSLGYDPIWFGVLMILNIVIAVQTPPYGFALFYLKGIAPKGI
TMMDIYKSVTPFILVQLVVLIICMVFPELVLWLPNKMMD

Sequences:

>Translated_439_residues
MEIELLTGILLLCILVAFALGAQVGLALAGIAMGVGYLVWGEALFNVIPSTVEGTFFNFILLAIPLYIYMGQILTRSGIG
DAMFNASQLVIGRLRGSLAISVIGVCSMIGAMVGIIGAGIMTSSSIALQPMLDRGYDKRLALGVIMAGGSLGILIPPSIP
MIMFAAATQNSVGRMFLAAMVPALITIVLLISYVLITCKLNPEKAPLDKENDIQIPKGYELFRTIRDGFSSLLLIVAVLG
SIIIGIATPTESGAIGVVGAIILAILFKRFKPAIMIKAGLQTSILVSVAMWIILGASVFSNFHLLMGVQTMVAGFATSLD
LPPIYIIIMFQLIMLLLGFIIDEFIIVLMCAPIFTPIAVSLGYDPIWFGVLMILNIVIAVQTPPYGFALFYLKGIAPKGI
TMMDIYKSVTPFILVQLVVLIICMVFPELVLWLPNKMMD
>Mature_439_residues
MEIELLTGILLLCILVAFALGAQVGLALAGIAMGVGYLVWGEALFNVIPSTVEGTFFNFILLAIPLYIYMGQILTRSGIG
DAMFNASQLVIGRLRGSLAISVIGVCSMIGAMVGIIGAGIMTSSSIALQPMLDRGYDKRLALGVIMAGGSLGILIPPSIP
MIMFAAATQNSVGRMFLAAMVPALITIVLLISYVLITCKLNPEKAPLDKENDIQIPKGYELFRTIRDGFSSLLLIVAVLG
SIIIGIATPTESGAIGVVGAIILAILFKRFKPAIMIKAGLQTSILVSVAMWIILGASVFSNFHLLMGVQTMVAGFATSLD
LPPIYIIIMFQLIMLLLGFIIDEFIIVLMCAPIFTPIAVSLGYDPIWFGVLMILNIVIAVQTPPYGFALFYLKGIAPKGI
TMMDIYKSVTPFILVQLVVLIICMVFPELVLWLPNKMMD

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=447, Percent_Identity=26.6219239373602, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 47075; Mature: 47075

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIELLTGILLLCILVAFALGAQVGLALAGIAMGVGYLVWGEALFNVIPSTVEGTFFNFI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LLAIPLYIYMGQILTRSGIGDAMFNASQLVIGRLRGSLAISVIGVCSMIGAMVGIIGAGI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTSSSIALQPMLDRGYDKRLALGVIMAGGSLGILIPPSIPMIMFAAATQNSVGRMFLAAM
HCCCCHHCCHHHHCCCCHHHHHHEEEECCCEEEEECCCCCHHHHHHHCCCHHHHHHHHHH
VPALITIVLLISYVLITCKLNPEKAPLDKENDIQIPKGYELFRTIRDGFSSLLLIVAVLG
HHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SIIIGIATPTESGAIGVVGAIILAILFKRFKPAIMIKAGLQTSILVSVAMWIILGASVFS
HHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
NFHLLMGVQTMVAGFATSLDLPPIYIIIMFQLIMLLLGFIIDEFIIVLMCAPIFTPIAVS
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGYDPIWFGVLMILNIVIAVQTPPYGFALFYLKGIAPKGITMMDIYKSVTPFILVQLVVL
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
IICMVFPELVLWLPNKMMD
HHHHHHHHHHHHCCHHHCC
>Mature Secondary Structure
MEIELLTGILLLCILVAFALGAQVGLALAGIAMGVGYLVWGEALFNVIPSTVEGTFFNFI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LLAIPLYIYMGQILTRSGIGDAMFNASQLVIGRLRGSLAISVIGVCSMIGAMVGIIGAGI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTSSSIALQPMLDRGYDKRLALGVIMAGGSLGILIPPSIPMIMFAAATQNSVGRMFLAAM
HCCCCHHCCHHHHCCCCHHHHHHEEEECCCEEEEECCCCCHHHHHHHCCCHHHHHHHHHH
VPALITIVLLISYVLITCKLNPEKAPLDKENDIQIPKGYELFRTIRDGFSSLLLIVAVLG
HHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SIIIGIATPTESGAIGVVGAIILAILFKRFKPAIMIKAGLQTSILVSVAMWIILGASVFS
HHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
NFHLLMGVQTMVAGFATSLDLPPIYIIIMFQLIMLLLGFIIDEFIIVLMCAPIFTPIAVS
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGYDPIWFGVLMILNIVIAVQTPPYGFALFYLKGIAPKGITMMDIYKSVTPFILVQLVVL
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
IICMVFPELVLWLPNKMMD
HHHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]