Click here to switch to the map view.

The map label for this gene is pilC [H]

Identifier: 119944257

GI number: 119944257

Start: 609052

End: 610284

Strand: Direct

Name: pilC [H]

Synonym: Ping_0481

Alternate gene names: 119944257

Gene position: 609052-610284 (Clockwise)

Preceding gene: 119944256

Following gene: 119944260

Centisome position: 13.36

GC content: 42.82

Gene sequence:

>1233_bases
ATGGCTGTAAAAAAGAAAACTAAAGGACCAGTCATTGATACTTTTAAATGGAAAGGCCTTAATCGTAAGGGCGCTGCAGT
ATCAGGCGAAATACAGGCTGAGAGTGTTGCAGAAGTTAAAATTGAACTGCGTAAGCAGAAGATTAATGTCACTAAAATAC
AGAAAAAATCCAAACCACTTTTCTCCTTCGGTAATAAAATAAAACCCATGGATATTGCGATTATTTCTCGCCAGATAGCC
ACTATGCTCGGAGCAGGTGTACCTTTAGTACAAGGTTTACAATTAATTGCCAAAAGCAGCGAAAAACCGGCATCGCGAAA
ATTAATGAGCACAATTTCTCAAGAGGTGGCAACGGGCACACCACTTTCACAAACCCTGCGTGGTCATTCCCTTTATTTTG
ATGATTTATACTGCGATCTTGTTTATGCCGGTGAGCAGTCTGGTGCATTAGATACAATTTACGACCGTATCTCTATTTAT
AAAGAAAAATCTGAAATTTTAAAATCAAAAATTAAAAAAGCGATGTTTTATCCAGCGGCGGTACTAACGGTTGCCGGCCT
GGTCACTCTGCTTTTACTGCTCTTTGTTATTCCGCAGTTTAAAGATATCTTTGAAGGTTTTGGCGCAGAGCTACCCGCTT
TTACGCTGTTTGTACTGGGCATTTCCGACTTTGTACAGTCTTACTGGTATATGATAGTCGGAGTGGTAATCGTTTTTCTC
TATCTGTTTAAAAAGGCGTATCGCCGCTCGCAGAAAGTGCGTGACAATACCGATAGATTTGTTCTTAAGATACCAGTGAT
CAGTACCATTTTAGATAAAGCGGCGGTGGCACGTTTTGCAAGAACCCTTTCTACTACCTTTGCTGCCGGTATTCCTTTGG
TTGACGGGCTAGTTTCCGCTGCGGGCGCTTCCGGAAATTATATTTATCGCACTGCGATTCTCAACGTGCGTGCGGAGGTA
ATTGCAGGCATGCAGATGCACATCGCCATGAAAACGACCACTGTTTTCCCCGATATGATAACCCAGATGGTGATGATCGG
TGAAGAGGCGGGTAATTTGGATGGTATGTTAAGCAAGGTTGCTGATATCTATGAACAGCAGGTTGATGATGCTGTTGATT
CCTTAACCAGCCTGTTGGAGCCGATGATCATGGTGGTTTTAGGGGTAGTGGTCGGCGGTTTGATTGTGGCTATGTATTTA
CCGATCTTCGCGTTAGGTACCGTTGTTGGTTAA

Upstream 100 bases:

>100_bases
TGTGATTAATGTGCTATTATTTTCGATTTTTAAATGAGATTGTGAAGCTTATTAAAAAACAAAAATTGCTGACCTATAGA
ATCATTAAGGAAGATTAATT

Downstream 100 bases:

>100_bases
CGGTTATTCATAATCGTTTCATGCATGTAAGAAAAGGGCTGTAACGTCTTTCTGTGCTTAGTTTTTTCTTTTTCTTAGGA
TAAAATAAAACCTTTCATTT

Product: type II secretion system protein, type IV pilus biogenesis protein PilC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MAVKKKTKGPVIDTFKWKGLNRKGAAVSGEIQAESVAEVKIELRKQKINVTKIQKKSKPLFSFGNKIKPMDIAIISRQIA
TMLGAGVPLVQGLQLIAKSSEKPASRKLMSTISQEVATGTPLSQTLRGHSLYFDDLYCDLVYAGEQSGALDTIYDRISIY
KEKSEILKSKIKKAMFYPAAVLTVAGLVTLLLLLFVIPQFKDIFEGFGAELPAFTLFVLGISDFVQSYWYMIVGVVIVFL
YLFKKAYRRSQKVRDNTDRFVLKIPVISTILDKAAVARFARTLSTTFAAGIPLVDGLVSAAGASGNYIYRTAILNVRAEV
IAGMQMHIAMKTTTVFPDMITQMVMIGEEAGNLDGMLSKVADIYEQQVDDAVDSLTSLLEPMIMVVLGVVVGGLIVAMYL
PIFALGTVVG

Sequences:

>Translated_410_residues
MAVKKKTKGPVIDTFKWKGLNRKGAAVSGEIQAESVAEVKIELRKQKINVTKIQKKSKPLFSFGNKIKPMDIAIISRQIA
TMLGAGVPLVQGLQLIAKSSEKPASRKLMSTISQEVATGTPLSQTLRGHSLYFDDLYCDLVYAGEQSGALDTIYDRISIY
KEKSEILKSKIKKAMFYPAAVLTVAGLVTLLLLLFVIPQFKDIFEGFGAELPAFTLFVLGISDFVQSYWYMIVGVVIVFL
YLFKKAYRRSQKVRDNTDRFVLKIPVISTILDKAAVARFARTLSTTFAAGIPLVDGLVSAAGASGNYIYRTAILNVRAEV
IAGMQMHIAMKTTTVFPDMITQMVMIGEEAGNLDGMLSKVADIYEQQVDDAVDSLTSLLEPMIMVVLGVVVGGLIVAMYL
PIFALGTVVG
>Mature_409_residues
AVKKKTKGPVIDTFKWKGLNRKGAAVSGEIQAESVAEVKIELRKQKINVTKIQKKSKPLFSFGNKIKPMDIAIISRQIAT
MLGAGVPLVQGLQLIAKSSEKPASRKLMSTISQEVATGTPLSQTLRGHSLYFDDLYCDLVYAGEQSGALDTIYDRISIYK
EKSEILKSKIKKAMFYPAAVLTVAGLVTLLLLLFVIPQFKDIFEGFGAELPAFTLFVLGISDFVQSYWYMIVGVVIVFLY
LFKKAYRRSQKVRDNTDRFVLKIPVISTILDKAAVARFARTLSTTFAAGIPLVDGLVSAAGASGNYIYRTAILNVRAEVI
AGMQMHIAMKTTTVFPDMITQMVMIGEEAGNLDGMLSKVADIYEQQVDDAVDSLTSLLEPMIMVVLGVVVGGLIVAMYLP
IFALGTVVG

Specific function: Involved in the translocation of the type IV pilin [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=401, Percent_Identity=26.1845386533666, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786295, Length=393, Percent_Identity=27.2264631043257, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44820; Mature: 44689

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVKKKTKGPVIDTFKWKGLNRKGAAVSGEIQAESVAEVKIELRKQKINVTKIQKKSKPL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCH
FSFGNKIKPMDIAIISRQIATMLGAGVPLVQGLQLIAKSSEKPASRKLMSTISQEVATGT
HHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
PLSQTLRGHSLYFDDLYCDLVYAGEQSGALDTIYDRISIYKEKSEILKSKIKKAMFYPAA
CHHHHHCCCCEEHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLTVAGLVTLLLLLFVIPQFKDIFEGFGAELPAFTLFVLGISDFVQSYWYMIVGVVIVFL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLFKKAYRRSQKVRDNTDRFVLKIPVISTILDKAAVARFARTLSTTFAAGIPLVDGLVSA
HHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AGASGNYIYRTAILNVRAEVIAGMQMHIAMKTTTVFPDMITQMVMIGEEAGNLDGMLSKV
CCCCCCEEEHHHHHHHHHHHHCCHHHEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ADIYEQQVDDAVDSLTSLLEPMIMVVLGVVVGGLIVAMYLPIFALGTVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8820654 [H]