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The map label for this gene is waaA [H]

Identifier: 119944117

GI number: 119944117

Start: 431801

End: 433045

Strand: Reverse

Name: waaA [H]

Synonym: Ping_0332

Alternate gene names: 119944117

Gene position: 433045-431801 (Counterclockwise)

Preceding gene: 119944118

Following gene: 119944116

Centisome position: 9.5

GC content: 40.32

Gene sequence:

>1245_bases
ATGCTTTTTATTTTATACCAGCTATTACAATTTTTATTTTTCCCTTTTATCTGCTTTACGCTGATCAAAAAAGCCAAGGG
AAAACTGCCCCTTAGCAAGCTGTTAGAATATTTAGGAATAGCTAAAAAACAGCCGTTCCCCGTCACCTGTTTTCACTGCG
TTTCTGTCGGTGAGGTATTAACCGCACTGCCTTTAATTAAGCAGTATCAAGTCCAGTACCCTGAGCAAAAACTGCTGATC
ACAACCACCACTTTTACCGGTTATCAGGAAGTTAAAAAAGCCTTTGGCGATAATATTGAGCACCGCTTTCTGCCGCTAGA
TTTTATCCTTTTCAGCAAACTGTTTTTTTCATGCCACAATATTCAGCGTATTAATATTATTGAAACAGAGCTCTGGCCAA
GTCTACTGCAACAGGCTAAACGACATAATGTACAGGTCTCTTTAATCAACGCCAGACTCTCAAAGCGCTCTGCCAAACGC
TACCTTAAATTTCCCCGCAGCGCATGCTGGCTGGTTAGCCACCTTGATAAAGTATTAGCCCAACATCAAGATGATGCGGA
TCGTTTTATTCAGCTGGGTGTCAGTAAAGACAAAATAACCATTACCGGCAGTATTAAATTCGATATAAAGATAGATCCGG
AAAAACAACAAAAAGGGGAATTATTAAAAAAAAAATGCAGCCACTTCCCTATTATTTTGGCGGCGAGCACCCATAAAGGG
GAAGATGAAATAATGCTAACTGCGTTTAAAACGCTACAGCAGACGGAGAAAAATGCACTGTTAATTATTGTCCCCCGACA
CCCGGAACGATTTGACAGTGTTTTTCACTTGGCAGAAAAAAAACAATTTAAAACCTGCCGGAAAACAGAGTACTCCCAGC
CACCTCAGGACTGCCAGGTTTATATTGGCGATACTATGGGTGAAATGATTATCTACCTAAGCCTAGCCGATTTAGTTATT
ATGGGCGGCAGTTTTGTGCCTGTCGGCGGGCATAATTTACTTGAACCCGCGGCCTTAAAAAAACCGGCCATAACCGGTCC
TTTTAATTTTAATTTTACCGATATCACTGAACAATTGATTAATGTGAAGCACACAATAAAAGCGGAAAATCCGCAGCAAT
TAACCCAGTTACTACTTAAACAGTGCTGGGATCCTGATAAATTAACCGAGCAGGGTGAGCAAGGATTAAAAGTGGTCAAA
AATAATCAAGGTGCATTAGAGAAAACATTAACATTGCTAATATGA

Upstream 100 bases:

>100_bases
GACTGAATCTATATTTACAATCAATTCAACGGTTATGTTCTATAGTTTTTCACTGATTATTTTTTACTCTTGTGCAAAAA
CAGCAAGAGATGAGACCTAG

Downstream 100 bases:

>100_bases
GCAAGTTAATTTAAAAATTTTACGCCTGAACAAGACTATCGTCGACATTGTACTTATGCACAGATATATTTGCAGGCAAC
ATTCAAACTATCTTTTTAAC

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MLFILYQLLQFLFFPFICFTLIKKAKGKLPLSKLLEYLGIAKKQPFPVTCFHCVSVGEVLTALPLIKQYQVQYPEQKLLI
TTTTFTGYQEVKKAFGDNIEHRFLPLDFILFSKLFFSCHNIQRINIIETELWPSLLQQAKRHNVQVSLINARLSKRSAKR
YLKFPRSACWLVSHLDKVLAQHQDDADRFIQLGVSKDKITITGSIKFDIKIDPEKQQKGELLKKKCSHFPIILAASTHKG
EDEIMLTAFKTLQQTEKNALLIIVPRHPERFDSVFHLAEKKQFKTCRKTEYSQPPQDCQVYIGDTMGEMIIYLSLADLVI
MGGSFVPVGGHNLLEPAALKKPAITGPFNFNFTDITEQLINVKHTIKAENPQQLTQLLLKQCWDPDKLTEQGEQGLKVVK
NNQGALEKTLTLLI

Sequences:

>Translated_414_residues
MLFILYQLLQFLFFPFICFTLIKKAKGKLPLSKLLEYLGIAKKQPFPVTCFHCVSVGEVLTALPLIKQYQVQYPEQKLLI
TTTTFTGYQEVKKAFGDNIEHRFLPLDFILFSKLFFSCHNIQRINIIETELWPSLLQQAKRHNVQVSLINARLSKRSAKR
YLKFPRSACWLVSHLDKVLAQHQDDADRFIQLGVSKDKITITGSIKFDIKIDPEKQQKGELLKKKCSHFPIILAASTHKG
EDEIMLTAFKTLQQTEKNALLIIVPRHPERFDSVFHLAEKKQFKTCRKTEYSQPPQDCQVYIGDTMGEMIIYLSLADLVI
MGGSFVPVGGHNLLEPAALKKPAITGPFNFNFTDITEQLINVKHTIKAENPQQLTQLLLKQCWDPDKLTEQGEQGLKVVK
NNQGALEKTLTLLI
>Mature_414_residues
MLFILYQLLQFLFFPFICFTLIKKAKGKLPLSKLLEYLGIAKKQPFPVTCFHCVSVGEVLTALPLIKQYQVQYPEQKLLI
TTTTFTGYQEVKKAFGDNIEHRFLPLDFILFSKLFFSCHNIQRINIIETELWPSLLQQAKRHNVQVSLINARLSKRSAKR
YLKFPRSACWLVSHLDKVLAQHQDDADRFIQLGVSKDKITITGSIKFDIKIDPEKQQKGELLKKKCSHFPIILAASTHKG
EDEIMLTAFKTLQQTEKNALLIIVPRHPERFDSVFHLAEKKQFKTCRKTEYSQPPQDCQVYIGDTMGEMIIYLSLADLVI
MGGSFVPVGGHNLLEPAALKKPAITGPFNFNFTDITEQLINVKHTIKAENPQQLTQLLLKQCWDPDKLTEQGEQGLKVVK
NNQGALEKTLTLLI

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers two molecules of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=416, Percent_Identity=35.3365384615385, Blast_Score=268, Evalue=4e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 47356; Mature: 47356

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFILYQLLQFLFFPFICFTLIKKAKGKLPLSKLLEYLGIAKKQPFPVTCFHCVSVGEVL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
TALPLIKQYQVQYPEQKLLITTTTFTGYQEVKKAFGDNIEHRFLPLDFILFSKLFFSCHN
HHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
IQRINIIETELWPSLLQQAKRHNVQVSLINARLSKRSAKRYLKFPRSACWLVSHLDKVLA
CCEEEEEHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QHQDDADRFIQLGVSKDKITITGSIKFDIKIDPEKQQKGELLKKKCSHFPIILAASTHKG
HCCCCHHHHHHHCCCCCEEEEEEEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCC
EDEIMLTAFKTLQQTEKNALLIIVPRHPERFDSVFHLAEKKQFKTCRKTEYSQPPQDCQV
CCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEE
YIGDTMGEMIIYLSLADLVIMGGSFVPVGGHNLLEPAALKKPAITGPFNFNFTDITEQLI
EECCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHH
NVKHTIKAENPQQLTQLLLKQCWDPDKLTEQGEQGLKVVKNNQGALEKTLTLLI
HHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHCC
>Mature Secondary Structure
MLFILYQLLQFLFFPFICFTLIKKAKGKLPLSKLLEYLGIAKKQPFPVTCFHCVSVGEVL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
TALPLIKQYQVQYPEQKLLITTTTFTGYQEVKKAFGDNIEHRFLPLDFILFSKLFFSCHN
HHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
IQRINIIETELWPSLLQQAKRHNVQVSLINARLSKRSAKRYLKFPRSACWLVSHLDKVLA
CCEEEEEHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QHQDDADRFIQLGVSKDKITITGSIKFDIKIDPEKQQKGELLKKKCSHFPIILAASTHKG
HCCCCHHHHHHHCCCCCEEEEEEEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCC
EDEIMLTAFKTLQQTEKNALLIIVPRHPERFDSVFHLAEKKQFKTCRKTEYSQPPQDCQV
CCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEE
YIGDTMGEMIIYLSLADLVIMGGSFVPVGGHNLLEPAALKKPAITGPFNFNFTDITEQLI
EECCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHH
NVKHTIKAENPQQLTQLLLKQCWDPDKLTEQGEQGLKVVKNNQGALEKTLTLLI
HHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]