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The map label for this gene is tatD [H]

Identifier: 119944102

GI number: 119944102

Start: 417747

End: 418544

Strand: Reverse

Name: tatD [H]

Synonym: Ping_0317

Alternate gene names: 119944102

Gene position: 418544-417747 (Counterclockwise)

Preceding gene: 119944103

Following gene: 119944101

Centisome position: 9.18

GC content: 43.36

Gene sequence:

>798_bases
ATGATTGATATTGGCGTCAACCTGACGAATAAACGCTTTCAAAAAGATATTAATGAAGTAATTGCTAACGCAAAGCAGGC
TGGTGTTAGCAGTATGATAATCACTGGAACAAATTTAGCTGAAAGTGAAGCTGCCCTGCAACTGGCTCAAAATTATCCCG
ATTATTTATTTTCGACTGCAGGCATTCATCCGCATGATGCGGACTCCTTTGATAAAACCAGCCTAAATCAACTTCGATCA
CTTGCCCAGGACCCCTCGGTAAAAGCCATTGGAGAGTGTGGTTTAGACTTTAACCGTAATTATTCAACGCCCGCTGAGCA
GGAATACGCCTTTATAGAACAGCTTGAGTTAGCCGTTGAGCTGCAATTACCTGTATTTATGCATGAGCGTGATGCTAACC
AGCGTTTTATCGAGCTGTTAAGCCCTTATGTCAAACAACTTCCAAATGCTGTCTTACACTGCTTCACGGGCGATCAGTTC
GATTTACAACGCTGCTTGGAAATTGATTTACACATTGGCATCACCGGTTGGATTTGCGATGAACGCCGTGGTGCCCACCT
GCTGGAGTTAGTTAAATTAATTCCCGCCAACCGCTTAATGATCGAAACAGACTCCCCCTATTTATTGCCTCGTTCAATGC
GCCCAAAACCCAAATCAAGCCGTAATGAACCAAAATACTTACCCTATATCGCGCAAACCATTGCCCATGCCCGGCAGCAA
AATGTTGAACAATTTATAGAACAAACAACACAAACCAGCCGAGCCTTTTTTAATATTGGCAGAGCGTTAACCGTTTAA

Upstream 100 bases:

>100_bases
GCCCATGCTGATTTTATTTGAGATTGGTTTACTGTTTTCCCGTTTTTATGTGCAACCGGCAGAAGATACAGACAATAGTG
AACAGGAGAACTGATGTTAA

Downstream 100 bases:

>100_bases
TAGGATTTATTCATGACCATTTCTCAGCACTTCCCTGCGCGACGCTTGCGTCGTTTGCGTAAGCATGATTTTTCTCGTCG
TTTAGTTGCCGAAAACCAGC

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MIDIGVNLTNKRFQKDINEVIANAKQAGVSSMIITGTNLAESEAALQLAQNYPDYLFSTAGIHPHDADSFDKTSLNQLRS
LAQDPSVKAIGECGLDFNRNYSTPAEQEYAFIEQLELAVELQLPVFMHERDANQRFIELLSPYVKQLPNAVLHCFTGDQF
DLQRCLEIDLHIGITGWICDERRGAHLLELVKLIPANRLMIETDSPYLLPRSMRPKPKSSRNEPKYLPYIAQTIAHARQQ
NVEQFIEQTTQTSRAFFNIGRALTV

Sequences:

>Translated_265_residues
MIDIGVNLTNKRFQKDINEVIANAKQAGVSSMIITGTNLAESEAALQLAQNYPDYLFSTAGIHPHDADSFDKTSLNQLRS
LAQDPSVKAIGECGLDFNRNYSTPAEQEYAFIEQLELAVELQLPVFMHERDANQRFIELLSPYVKQLPNAVLHCFTGDQF
DLQRCLEIDLHIGITGWICDERRGAHLLELVKLIPANRLMIETDSPYLLPRSMRPKPKSSRNEPKYLPYIAQTIAHARQQ
NVEQFIEQTTQTSRAFFNIGRALTV
>Mature_265_residues
MIDIGVNLTNKRFQKDINEVIANAKQAGVSSMIITGTNLAESEAALQLAQNYPDYLFSTAGIHPHDADSFDKTSLNQLRS
LAQDPSVKAIGECGLDFNRNYSTPAEQEYAFIEQLELAVELQLPVFMHERDANQRFIELLSPYVKQLPNAVLHCFTGDQF
DLQRCLEIDLHIGITGWICDERRGAHLLELVKLIPANRLMIETDSPYLLPRSMRPKPKSSRNEPKYLPYIAQTIAHARQQ
NVEQFIEQTTQTSRAFFNIGRALTV

Specific function: Shows DNase activity [H]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=276, Percent_Identity=32.9710144927536, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI225903439, Length=234, Percent_Identity=32.4786324786325, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=28.996282527881, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI110349734, Length=269, Percent_Identity=29.368029739777, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI226061853, Length=276, Percent_Identity=28.9855072463768, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI225903424, Length=190, Percent_Identity=30, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI226061614, Length=261, Percent_Identity=27.5862068965517, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=27.9475982532751, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI48994985, Length=260, Percent_Identity=53.4615384615385, Blast_Score=299, Evalue=1e-82,
Organism=Escherichia coli, GI1787342, Length=253, Percent_Identity=30.0395256916996, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082439, Length=262, Percent_Identity=26.3358778625954, Blast_Score=88, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17559024, Length=280, Percent_Identity=35.7142857142857, Blast_Score=200, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI71980746, Length=267, Percent_Identity=26.5917602996255, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17543026, Length=224, Percent_Identity=26.7857142857143, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565396, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319416, Length=294, Percent_Identity=27.2108843537415, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24648690, Length=284, Percent_Identity=32.0422535211268, Blast_Score=168, Evalue=3e-42,
Organism=Drosophila melanogaster, GI221330018, Length=303, Percent_Identity=30.6930693069307, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24586117, Length=290, Percent_Identity=29.3103448275862, Blast_Score=110, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29989; Mature: 29989

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDIGVNLTNKRFQKDINEVIANAKQAGVSSMIITGTNLAESEAALQLAQNYPDYLFSTA
CEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHCC
GIHPHDADSFDKTSLNQLRSLAQDPSVKAIGECGLDFNRNYSTPAEQEYAFIEQLELAVE
CCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHE
LQLPVFMHERDANQRFIELLSPYVKQLPNAVLHCFTGDQFDLQRCLEIDLHIGITGWICD
ECCCCEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHEECEEEEEEC
ERRGAHLLELVKLIPANRLMIETDSPYLLPRSMRPKPKSSRNEPKYLPYIAQTIAHARQQ
CCCCHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
NVEQFIEQTTQTSRAFFNIGRALTV
HHHHHHHHHHHHHHHHHHHCHHHCC
>Mature Secondary Structure
MIDIGVNLTNKRFQKDINEVIANAKQAGVSSMIITGTNLAESEAALQLAQNYPDYLFSTA
CEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHCC
GIHPHDADSFDKTSLNQLRSLAQDPSVKAIGECGLDFNRNYSTPAEQEYAFIEQLELAVE
CCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHE
LQLPVFMHERDANQRFIELLSPYVKQLPNAVLHCFTGDQFDLQRCLEIDLHIGITGWICD
ECCCCEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHEECEEEEEEC
ERRGAHLLELVKLIPANRLMIETDSPYLLPRSMRPKPKSSRNEPKYLPYIAQTIAHARQQ
CCCCHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
NVEQFIEQTTQTSRAFFNIGRALTV
HHHHHHHHHHHHHHHHHHHCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]