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The map label for this gene is putA [H]

Identifier: 119944085

GI number: 119944085

Start: 391237

End: 395031

Strand: Reverse

Name: putA [H]

Synonym: Ping_0300

Alternate gene names: 119944085

Gene position: 395031-391237 (Counterclockwise)

Preceding gene: 119944087

Following gene: 119944084

Centisome position: 8.66

GC content: 44.51

Gene sequence:

>3795_bases
ATGTTGTTTGATGGTAACTTAGTCGCCGATTCTACTATTCGTCAAAAAATTCGAGATTTTCATCGTATCGATGAAAACTT
GGCTGTTGATCATATTTTGCCTGAGGCAGAAGTTAATATGCGAGCACGTAGCCGTGCCTGGGAGCGAGCGCGCAAAATGG
TGCTGCAAATACGCCGTGAACAGGAAGGTACTGGCGTTGTTGAAGCATTACTCAATGAGTATTCTCTTTCTTCGGCTGAA
GGTGTGGTGCTAATGTGCCTAGCGGAAGCATTATTACGGGTACCTGACAAAAAAACTCAGGATGAGCTGATCCGCGATAA
GCTTTCAAAGGGAAAATGGAGTACGCATTTAGGTACCAGTAATTCACTCTTTGTGAATGCATCATCCTGGGGCCTGCTGT
TAACCGGCAGCATGGTTAACTTCAGCGATACTCGCAAAAGCAATCAGTTTGGTTTATTGAAAAAAACCCTTGGCCGAATG
GGTGAACCAGTTATTCGTAAAGCCATGAATATTGCGATGAAAGTCATGGGAGAGCAGTTCGTAATAGGTGAAACTATTGT
TGCTGCGGTCAAGCGTGCGGAACAAAAAGAACGTAATGGTTATGTCTATTCTTACGATGTGCTGGGTGAAGGCGCAAGAA
CTGAAAAAGATGCGGAGCGTTATTTTCAATCCTATGTTAAGGCACTCGTTGTTATTGGTGAAGCCGCTAAAGGCAGAGGC
CCTCGAAAAAGCCCTGGGATCTCAGTTAAATTGTCAGCGATTCATCCCCGCTACGAGTTTAGTCACAGAGACAGAGTGCT
TAAGGAACTCCCGCAAAAACTAAAATCCTTATGTTTACTGGCAAAAAAATATGATATTGGTTTAACGGTCGATGCTGAAG
AATCTGAGCGTCTGGATATCTCTCTTGATATTATTGAAATAGTATTTAGCGATCCTGAGTTAAGTGATTGGGATGGTTTC
GGTTTGGCGGTTCAAGCTTATCAGAAGCGGGCTATTTTTGTGATCGACTGGTTGCGCGAGCTAACCGAGAAAGTGGGTCG
TAAAATGATGGTACGACTGGTCAAAGGAGCTTATTGGGATACTGAGATAAAAAATGCGCAAAAAGACGGGCTTGAGCATT
ATCCTGTCTTCACCCGTAAGTCTTCCACCGATGTGTCTTATCATGCCTGTGCTAATCGCCTGTTAGACTATCGCGATACT
ATCTATCCTCAATTTGCAACGCATAATGCTTATACCGCATCGGTCATTATTGAGCTTGCCGGTGATGATAAAGAAGGCTT
TGAATTCCAATGTTTACATGGCATGGGAGACAGTTTGTATGATCAAATTGTGACCACTGATAATATTCAATGTCGAATTT
ACGCACCCGTTGGTCAGCATGAAGATCTGCTCGCTTATCTGGTACGTCGTCTGCTGGAAAATGGTGCTAATTCTTCTTTT
GTTAATGCCATCGTTGATGAAACCCGTCCAGTTGAATCTTTGCTTGAAGATCCTGTCGAAAAAACCCAGCGACTTAAAGT
TACCTACAATGAGCAGATACTTAAACCGATCGATTTATTTGGTAAGGAAAGAGATAATTCCAAAGGGCTTGACCTTAACG
ATATCAATCAGATAACGCCATTAAGAGAATCGCTCGATCGTTGGTTCAATGATCACTTGCTCACATCAGACCAAGTGCCT
GATGATTGTTTTGCGGTAAAAAATCCGGCTGACCATAATGAAATAATTGGCTTCCATCGTCATGACAGCCGAGAGGAAAT
GGTAGCTAAGCTTGAAAAAGCTCACAACAGTTTCGCGACTTGGTCACAAACTCCGATTGAGGAGAGAGCTAGTTTACTAA
GACGAACCGCTGATATTTTAGAACGTCACATGGACGAACTCATTGCGATTTGTATTAAAGAAGCAGGAAAAATTGCTCAG
GACGGCATTGATGAAGTCCGTGAGGCAGTCGATTTTTGTCGTTATTACGCGGCTAGAGCCGAAGAACTTGCCGAAGATGA
CAGACTAGAGCCGCGCGGTGTGGTTTTATGTATCAGCCCATGGAACTTTCCGCTGGCGATATTTATGGGTCAGGTTGCGG
CAGCAATTGTAACGGGTAACACAGTAATAGCTAAACCCGCTGAACAAACCAGCCTGATAGCTTTACGCGCTCTCGAATTA
ATGGAGTCTGTGGGCATGCCCGAGGGCACAGTGACAGCCGTTATTGCTAGAGGTCCTGCCGTTGGTGAAGCGCTGCTTGA
AGATGAGCGAATTAAGGCGGTAGTATTTACCGGCTCAACAACGACTGGAACACATATTTCCCGCATTCTGGCAAACCGGG
GTGGAGATCAAATACCGCTGATCGCAGAGACTGGGGGCCAGAACTGTATGGTGGTCGACTCAACCGCCTTGCCTGAGCAA
GTCATTGATGATGTCATTTCATCGGGCTTCCAAAGTGCAGGACAACGCTGTTCAGCTCTGCGCGTCTTATTTTTACAGGA
AGAAATTGCCGATGGTATGACCGAGATGTTGATCGGTGCGCTAAAGGAACTTCATATTGGTGACCCTGCTCAACTATCAA
CAGACGTTGGACCGGTGATTGACAGCAAAGCATTAAATAGCCTGGAAGCTCATGTTAAAGATATGGAGAATAAAGCTGAA
CTGCTTTATGAATGTCCGGTACCTGAAAATAACGGCACATTTTTTGCCCCACGTCTTTACCAGATAGCAGACATCTCGGT
ATTAGAACGCGAAGTTTTTGGTCCTTGCGTGCATATCGTCCGGTTTAAGGGCGACCAACTTGCAAATACCATCGAAAAAA
TCAATGCCACTGGATTTGGATTAACCATGGGTATTCATACTCGCATTGAAGAGCGCGCCATTGAACTCGCTAAGTTGTCG
CGCGCAGGGAATGTCTACATCAATCGTAATATGATAGGTGCGGTGGTTGGAGTACAACCCTTTGGTGGAACAGGTTTATC
CGGTACAGGTCCAAAAGCAGGCGGACCTAATTATCTTTCTCGCTTTATGAATGAAAAGGCAACGCCAGCACCACATCAGG
ATGATAGTGTATTGGGTGACGACAAAGCGCTGATCAGTGATAAGGTATCAAATCTGGAAACGCTTGCCTTTATGAAAAAT
GCTATCAAAGTAGAGCCTGAATGGCGGGTAACTAATTTAAATGATCGTATTTCTGCAGTGCGTCAGCTTCTTGCCCAAAT
TGCGAAGGTGACCATTGTTGAAGAATTAGCCGATGATTTTAATTCAACACTCGCGGCAGCAAGATCGCAGCTGATAAGCA
TTGAAAAAAAGATGAGAAGACCAAAGGCACTGCCTGGGCCTACCGGTGAATCTAACGTATTGTACTTAGAGCCTCGCGGT
ATTCTGGTATGTTTTGCGGATAAAAATGTAACTTTCGAATATTGGACCTTAGCAATAGTAACTGCATTAGCCACCGGTAA
TACGGTTATTTCGGTGGTTTCTGACTTGTTTTATGAGGAAGCATTGGCATTCAGAGATAAATTTAACGCGACGGGTGCTC
CTGAAGGAGTGCTTCAAGTAGCTAAATTATGTCATTTAGAAGCCTTACTGGAGCAGGATAAATTGGCGGGTGTGGTCATT
GACAGTCACAGTCCACGTCGTACCTTTATGGTGCGTAAATTGGCCGAACGTGAAGGTGCAATACTGCCGGTAATAACCTC
AGAATACACTGATCACTTGATTCAACGACTACTCACTGAAAAGAGCATCAGTATAGATATCACTGCATCAGGCGGTAATA
CCTCTCTGATGACCTTGGTTGAAGAGGAAGACTAG

Upstream 100 bases:

>100_bases
TTTTTTTTTATTTCGCTAAAGATTGTTCGAACAATCTGCTATATACTCGCCAATTATTCCTTTCCTTATATTTAAGTATT
TAGCTTCCTGGGGGTTGCGT

Downstream 100 bases:

>100_bases
TTATTTTTTTGTAAAAGTAAACGTGGTTTTTTGAGCTAAAAACCACGTTTATTTATTACCTTCCGGAGTTTAATAGCGCA
GGCTTTTCAGATAACCGATC

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1264; Mature: 1264

Protein sequence:

>1264_residues
MLFDGNLVADSTIRQKIRDFHRIDENLAVDHILPEAEVNMRARSRAWERARKMVLQIRREQEGTGVVEALLNEYSLSSAE
GVVLMCLAEALLRVPDKKTQDELIRDKLSKGKWSTHLGTSNSLFVNASSWGLLLTGSMVNFSDTRKSNQFGLLKKTLGRM
GEPVIRKAMNIAMKVMGEQFVIGETIVAAVKRAEQKERNGYVYSYDVLGEGARTEKDAERYFQSYVKALVVIGEAAKGRG
PRKSPGISVKLSAIHPRYEFSHRDRVLKELPQKLKSLCLLAKKYDIGLTVDAEESERLDISLDIIEIVFSDPELSDWDGF
GLAVQAYQKRAIFVIDWLRELTEKVGRKMMVRLVKGAYWDTEIKNAQKDGLEHYPVFTRKSSTDVSYHACANRLLDYRDT
IYPQFATHNAYTASVIIELAGDDKEGFEFQCLHGMGDSLYDQIVTTDNIQCRIYAPVGQHEDLLAYLVRRLLENGANSSF
VNAIVDETRPVESLLEDPVEKTQRLKVTYNEQILKPIDLFGKERDNSKGLDLNDINQITPLRESLDRWFNDHLLTSDQVP
DDCFAVKNPADHNEIIGFHRHDSREEMVAKLEKAHNSFATWSQTPIEERASLLRRTADILERHMDELIAICIKEAGKIAQ
DGIDEVREAVDFCRYYAARAEELAEDDRLEPRGVVLCISPWNFPLAIFMGQVAAAIVTGNTVIAKPAEQTSLIALRALEL
MESVGMPEGTVTAVIARGPAVGEALLEDERIKAVVFTGSTTTGTHISRILANRGGDQIPLIAETGGQNCMVVDSTALPEQ
VIDDVISSGFQSAGQRCSALRVLFLQEEIADGMTEMLIGALKELHIGDPAQLSTDVGPVIDSKALNSLEAHVKDMENKAE
LLYECPVPENNGTFFAPRLYQIADISVLEREVFGPCVHIVRFKGDQLANTIEKINATGFGLTMGIHTRIEERAIELAKLS
RAGNVYINRNMIGAVVGVQPFGGTGLSGTGPKAGGPNYLSRFMNEKATPAPHQDDSVLGDDKALISDKVSNLETLAFMKN
AIKVEPEWRVTNLNDRISAVRQLLAQIAKVTIVEELADDFNSTLAAARSQLISIEKKMRRPKALPGPTGESNVLYLEPRG
ILVCFADKNVTFEYWTLAIVTALATGNTVISVVSDLFYEEALAFRDKFNATGAPEGVLQVAKLCHLEALLEQDKLAGVVI
DSHSPRRTFMVRKLAEREGAILPVITSEYTDHLIQRLLTEKSISIDITASGGNTSLMTLVEEED

Sequences:

>Translated_1264_residues
MLFDGNLVADSTIRQKIRDFHRIDENLAVDHILPEAEVNMRARSRAWERARKMVLQIRREQEGTGVVEALLNEYSLSSAE
GVVLMCLAEALLRVPDKKTQDELIRDKLSKGKWSTHLGTSNSLFVNASSWGLLLTGSMVNFSDTRKSNQFGLLKKTLGRM
GEPVIRKAMNIAMKVMGEQFVIGETIVAAVKRAEQKERNGYVYSYDVLGEGARTEKDAERYFQSYVKALVVIGEAAKGRG
PRKSPGISVKLSAIHPRYEFSHRDRVLKELPQKLKSLCLLAKKYDIGLTVDAEESERLDISLDIIEIVFSDPELSDWDGF
GLAVQAYQKRAIFVIDWLRELTEKVGRKMMVRLVKGAYWDTEIKNAQKDGLEHYPVFTRKSSTDVSYHACANRLLDYRDT
IYPQFATHNAYTASVIIELAGDDKEGFEFQCLHGMGDSLYDQIVTTDNIQCRIYAPVGQHEDLLAYLVRRLLENGANSSF
VNAIVDETRPVESLLEDPVEKTQRLKVTYNEQILKPIDLFGKERDNSKGLDLNDINQITPLRESLDRWFNDHLLTSDQVP
DDCFAVKNPADHNEIIGFHRHDSREEMVAKLEKAHNSFATWSQTPIEERASLLRRTADILERHMDELIAICIKEAGKIAQ
DGIDEVREAVDFCRYYAARAEELAEDDRLEPRGVVLCISPWNFPLAIFMGQVAAAIVTGNTVIAKPAEQTSLIALRALEL
MESVGMPEGTVTAVIARGPAVGEALLEDERIKAVVFTGSTTTGTHISRILANRGGDQIPLIAETGGQNCMVVDSTALPEQ
VIDDVISSGFQSAGQRCSALRVLFLQEEIADGMTEMLIGALKELHIGDPAQLSTDVGPVIDSKALNSLEAHVKDMENKAE
LLYECPVPENNGTFFAPRLYQIADISVLEREVFGPCVHIVRFKGDQLANTIEKINATGFGLTMGIHTRIEERAIELAKLS
RAGNVYINRNMIGAVVGVQPFGGTGLSGTGPKAGGPNYLSRFMNEKATPAPHQDDSVLGDDKALISDKVSNLETLAFMKN
AIKVEPEWRVTNLNDRISAVRQLLAQIAKVTIVEELADDFNSTLAAARSQLISIEKKMRRPKALPGPTGESNVLYLEPRG
ILVCFADKNVTFEYWTLAIVTALATGNTVISVVSDLFYEEALAFRDKFNATGAPEGVLQVAKLCHLEALLEQDKLAGVVI
DSHSPRRTFMVRKLAEREGAILPVITSEYTDHLIQRLLTEKSISIDITASGGNTSLMTLVEEED
>Mature_1264_residues
MLFDGNLVADSTIRQKIRDFHRIDENLAVDHILPEAEVNMRARSRAWERARKMVLQIRREQEGTGVVEALLNEYSLSSAE
GVVLMCLAEALLRVPDKKTQDELIRDKLSKGKWSTHLGTSNSLFVNASSWGLLLTGSMVNFSDTRKSNQFGLLKKTLGRM
GEPVIRKAMNIAMKVMGEQFVIGETIVAAVKRAEQKERNGYVYSYDVLGEGARTEKDAERYFQSYVKALVVIGEAAKGRG
PRKSPGISVKLSAIHPRYEFSHRDRVLKELPQKLKSLCLLAKKYDIGLTVDAEESERLDISLDIIEIVFSDPELSDWDGF
GLAVQAYQKRAIFVIDWLRELTEKVGRKMMVRLVKGAYWDTEIKNAQKDGLEHYPVFTRKSSTDVSYHACANRLLDYRDT
IYPQFATHNAYTASVIIELAGDDKEGFEFQCLHGMGDSLYDQIVTTDNIQCRIYAPVGQHEDLLAYLVRRLLENGANSSF
VNAIVDETRPVESLLEDPVEKTQRLKVTYNEQILKPIDLFGKERDNSKGLDLNDINQITPLRESLDRWFNDHLLTSDQVP
DDCFAVKNPADHNEIIGFHRHDSREEMVAKLEKAHNSFATWSQTPIEERASLLRRTADILERHMDELIAICIKEAGKIAQ
DGIDEVREAVDFCRYYAARAEELAEDDRLEPRGVVLCISPWNFPLAIFMGQVAAAIVTGNTVIAKPAEQTSLIALRALEL
MESVGMPEGTVTAVIARGPAVGEALLEDERIKAVVFTGSTTTGTHISRILANRGGDQIPLIAETGGQNCMVVDSTALPEQ
VIDDVISSGFQSAGQRCSALRVLFLQEEIADGMTEMLIGALKELHIGDPAQLSTDVGPVIDSKALNSLEAHVKDMENKAE
LLYECPVPENNGTFFAPRLYQIADISVLEREVFGPCVHIVRFKGDQLANTIEKINATGFGLTMGIHTRIEERAIELAKLS
RAGNVYINRNMIGAVVGVQPFGGTGLSGTGPKAGGPNYLSRFMNEKATPAPHQDDSVLGDDKALISDKVSNLETLAFMKN
AIKVEPEWRVTNLNDRISAVRQLLAQIAKVTIVEELADDFNSTLAAARSQLISIEKKMRRPKALPGPTGESNVLYLEPRG
ILVCFADKNVTFEYWTLAIVTALATGNTVISVVSDLFYEEALAFRDKFNATGAPEGVLQVAKLCHLEALLEQDKLAGVVI
DSHSPRRTFMVRKLAEREGAILPVITSEYTDHLIQRLLTEKSISIDITASGGNTSLMTLVEEED

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI153266822, Length=450, Percent_Identity=29.5555555555556, Blast_Score=185, Evalue=2e-46,
Organism=Homo sapiens, GI25777730, Length=456, Percent_Identity=29.1666666666667, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI238859541, Length=478, Percent_Identity=27.4058577405858, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI21361176, Length=457, Percent_Identity=29.1028446389497, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI25777736, Length=478, Percent_Identity=27.4058577405858, Blast_Score=178, Evalue=4e-44,
Organism=Homo sapiens, GI25777734, Length=478, Percent_Identity=27.4058577405858, Blast_Score=178, Evalue=4e-44,
Organism=Homo sapiens, GI21614513, Length=416, Percent_Identity=28.8461538461538, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI25777724, Length=449, Percent_Identity=29.3986636971047, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI25777732, Length=457, Percent_Identity=28.6652078774617, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI12007648, Length=443, Percent_Identity=27.765237020316, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI238814322, Length=413, Percent_Identity=29.0556900726392, Blast_Score=167, Evalue=5e-41,
Organism=Homo sapiens, GI25777728, Length=402, Percent_Identity=30.5970149253731, Blast_Score=160, Evalue=5e-39,
Organism=Homo sapiens, GI115387104, Length=447, Percent_Identity=29.5302013422819, Blast_Score=160, Evalue=9e-39,
Organism=Homo sapiens, GI4507229, Length=413, Percent_Identity=29.7820823244552, Blast_Score=154, Evalue=4e-37,
Organism=Homo sapiens, GI188035924, Length=447, Percent_Identity=26.8456375838926, Blast_Score=152, Evalue=3e-36,
Organism=Homo sapiens, GI310128093, Length=447, Percent_Identity=26.6219239373602, Blast_Score=151, Evalue=5e-36,
Organism=Homo sapiens, GI310128103, Length=447, Percent_Identity=26.6219239373602, Blast_Score=151, Evalue=5e-36,
Organism=Homo sapiens, GI25777721, Length=426, Percent_Identity=28.6384976525822, Blast_Score=144, Evalue=5e-34,
Organism=Homo sapiens, GI25952152, Length=435, Percent_Identity=26.8965517241379, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI25777726, Length=449, Percent_Identity=26.7260579064588, Blast_Score=131, Evalue=4e-30,
Organism=Homo sapiens, GI310128091, Length=382, Percent_Identity=26.9633507853403, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI11095441, Length=436, Percent_Identity=26.8348623853211, Blast_Score=124, Evalue=7e-28,
Organism=Homo sapiens, GI310128087, Length=273, Percent_Identity=27.8388278388278, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI310128099, Length=224, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=5e-20,
Organism=Homo sapiens, GI310128101, Length=221, Percent_Identity=28.5067873303167, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI4502043, Length=333, Percent_Identity=26.7267267267267, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI238814371, Length=333, Percent_Identity=26.7267267267267, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI71773324, Length=333, Percent_Identity=26.7267267267267, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI310128089, Length=327, Percent_Identity=25.3822629969419, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI206597441, Length=437, Percent_Identity=24.0274599542334, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI206597439, Length=437, Percent_Identity=24.0274599542334, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI22907049, Length=437, Percent_Identity=24.0274599542334, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI310128095, Length=308, Percent_Identity=25.974025974026, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI73695881, Length=336, Percent_Identity=25, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI73695879, Length=336, Percent_Identity=25, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI301500698, Length=277, Percent_Identity=25.2707581227437, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI310128097, Length=255, Percent_Identity=26.2745098039216, Blast_Score=81, Evalue=8e-15,
Organism=Homo sapiens, GI73466520, Length=335, Percent_Identity=22.9850746268657, Blast_Score=72, Evalue=5e-12,
Organism=Homo sapiens, GI4557303, Length=335, Percent_Identity=22.9850746268657, Blast_Score=71, Evalue=7e-12,
Organism=Escherichia coli, GI1787250, Length=1291, Percent_Identity=44.5391169635941, Blast_Score=1033, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=452, Percent_Identity=30.3097345132743, Blast_Score=191, Evalue=4e-49,
Organism=Escherichia coli, GI87081896, Length=500, Percent_Identity=29.6, Blast_Score=182, Evalue=1e-46,
Organism=Escherichia coli, GI1787684, Length=456, Percent_Identity=28.9473684210526, Blast_Score=168, Evalue=2e-42,
Organism=Escherichia coli, GI1787558, Length=408, Percent_Identity=30.1470588235294, Blast_Score=167, Evalue=4e-42,
Organism=Escherichia coli, GI1787715, Length=407, Percent_Identity=29.7297297297297, Blast_Score=162, Evalue=9e-41,
Organism=Escherichia coli, GI1788042, Length=410, Percent_Identity=29.0243902439024, Blast_Score=150, Evalue=6e-37,
Organism=Escherichia coli, GI1786504, Length=451, Percent_Identity=27.0509977827051, Blast_Score=145, Evalue=2e-35,
Organism=Escherichia coli, GI87082295, Length=429, Percent_Identity=29.3706293706294, Blast_Score=140, Evalue=7e-34,
Organism=Escherichia coli, GI87081926, Length=414, Percent_Identity=27.536231884058, Blast_Score=127, Evalue=5e-30,
Organism=Escherichia coli, GI1787653, Length=349, Percent_Identity=23.2091690544413, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17534447, Length=461, Percent_Identity=29.5010845986985, Blast_Score=185, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI133930964, Length=413, Percent_Identity=29.2978208232446, Blast_Score=170, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI115534176, Length=452, Percent_Identity=28.0973451327434, Blast_Score=164, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI25143874, Length=549, Percent_Identity=26.5938069216758, Blast_Score=163, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17562198, Length=449, Percent_Identity=28.9532293986637, Blast_Score=163, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI25143876, Length=493, Percent_Identity=27.3833671399594, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI25144435, Length=451, Percent_Identity=28.8248337028825, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI115532534, Length=396, Percent_Identity=29.7979797979798, Blast_Score=159, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI32564736, Length=404, Percent_Identity=29.7029702970297, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17551164, Length=452, Percent_Identity=29.2035398230088, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32564151, Length=412, Percent_Identity=27.6699029126214, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17534119, Length=462, Percent_Identity=27.0562770562771, Blast_Score=141, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71995606, Length=425, Percent_Identity=25.8823529411765, Blast_Score=130, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71986308, Length=441, Percent_Identity=26.7573696145125, Blast_Score=128, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71995613, Length=382, Percent_Identity=24.6073298429319, Blast_Score=120, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71990744, Length=297, Percent_Identity=28.6195286195286, Blast_Score=114, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17564084, Length=342, Percent_Identity=26.6081871345029, Blast_Score=95, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25146391, Length=343, Percent_Identity=23.3236151603499, Blast_Score=90, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI25146394, Length=343, Percent_Identity=23.3236151603499, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32566756, Length=343, Percent_Identity=23.3236151603499, Blast_Score=89, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321826, Length=483, Percent_Identity=28.3643892339545, Blast_Score=183, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6324950, Length=464, Percent_Identity=30.3879310344828, Blast_Score=182, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6320917, Length=466, Percent_Identity=30.0429184549356, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6325196, Length=450, Percent_Identity=29.5555555555556, Blast_Score=167, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6323821, Length=487, Percent_Identity=29.1581108829569, Blast_Score=164, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6323822, Length=451, Percent_Identity=29.2682926829268, Blast_Score=164, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6319478, Length=449, Percent_Identity=28.7305122494432, Blast_Score=161, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6321828, Length=469, Percent_Identity=25.3731343283582, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585660, Length=435, Percent_Identity=29.6551724137931, Blast_Score=187, Evalue=4e-47,
Organism=Drosophila melanogaster, GI281362580, Length=449, Percent_Identity=28.5077951002227, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI62472918, Length=449, Percent_Identity=28.5077951002227, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI62472926, Length=449, Percent_Identity=28.5077951002227, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI62472936, Length=449, Percent_Identity=28.5077951002227, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI21356737, Length=449, Percent_Identity=28.5077951002227, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24668425, Length=466, Percent_Identity=27.4678111587983, Blast_Score=174, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24668417, Length=466, Percent_Identity=27.4678111587983, Blast_Score=174, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24668413, Length=466, Percent_Identity=27.4678111587983, Blast_Score=174, Evalue=5e-43,
Organism=Drosophila melanogaster, GI20129399, Length=451, Percent_Identity=29.7117516629712, Blast_Score=172, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24650465, Length=461, Percent_Identity=28.4164859002169, Blast_Score=164, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24666674, Length=438, Percent_Identity=29.6803652968037, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI28574525, Length=452, Percent_Identity=25.2212389380531, Blast_Score=137, Evalue=5e-32,
Organism=Drosophila melanogaster, GI28571798, Length=461, Percent_Identity=23.8611713665944, Blast_Score=129, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28571796, Length=461, Percent_Identity=23.8611713665944, Blast_Score=129, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28571794, Length=461, Percent_Identity=23.8611713665944, Blast_Score=129, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28571806, Length=461, Percent_Identity=23.8611713665944, Blast_Score=129, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28571802, Length=461, Percent_Identity=23.8611713665944, Blast_Score=129, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28571800, Length=461, Percent_Identity=23.8611713665944, Blast_Score=129, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24638878, Length=426, Percent_Identity=27.2300469483568, Blast_Score=110, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24638876, Length=426, Percent_Identity=27.2300469483568, Blast_Score=109, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281360299, Length=369, Percent_Identity=26.8292682926829, Blast_Score=103, Evalue=7e-22,
Organism=Drosophila melanogaster, GI281360297, Length=369, Percent_Identity=26.8292682926829, Blast_Score=103, Evalue=7e-22,
Organism=Drosophila melanogaster, GI281360295, Length=369, Percent_Identity=26.8292682926829, Blast_Score=103, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24586250, Length=369, Percent_Identity=26.8292682926829, Blast_Score=103, Evalue=7e-22,
Organism=Drosophila melanogaster, GI281360301, Length=369, Percent_Identity=26.8292682926829, Blast_Score=103, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45552499, Length=369, Percent_Identity=26.2872628726287, Blast_Score=101, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281360303, Length=369, Percent_Identity=26.2872628726287, Blast_Score=100, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 140325; Mature: 140325

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFDGNLVADSTIRQKIRDFHRIDENLAVDHILPEAEVNMRARSRAWERARKMVLQIRRE
CEECCCEECHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QEGTGVVEALLNEYSLSSAEGVVLMCLAEALLRVPDKKTQDELIRDKLSKGKWSTHLGTS
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCC
NSLFVNASSWGLLLTGSMVNFSDTRKSNQFGLLKKTLGRMGEPVIRKAMNIAMKVMGEQF
CCEEEECCCCCEEEECCEECCHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCHH
VIGETIVAAVKRAEQKERNGYVYSYDVLGEGARTEKDAERYFQSYVKALVVIGEAAKGRG
HHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCC
PRKSPGISVKLSAIHPRYEFSHRDRVLKELPQKLKSLCLLAKKYDIGLTVDAEESERLDI
CCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEE
SLDIIEIVFSDPELSDWDGFGLAVQAYQKRAIFVIDWLRELTEKVGRKMMVRLVKGAYWD
EEEEEEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TEIKNAQKDGLEHYPVFTRKSSTDVSYHACANRLLDYRDTIYPQFATHNAYTASVIIELA
HHHCCHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCEEEEEEEEEE
GDDKEGFEFQCLHGMGDSLYDQIVTTDNIQCRIYAPVGQHEDLLAYLVRRLLENGANSSF
CCCCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHH
VNAIVDETRPVESLLEDPVEKTQRLKVTYNEQILKPIDLFGKERDNSKGLDLNDINQITP
HHHHHHCCCHHHHHHHCHHHHHHEEEEEECHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
LRESLDRWFNDHLLTSDQVPDDCFAVKNPADHNEIIGFHRHDSREEMVAKLEKAHNSFAT
HHHHHHHHHHCCCCCCCCCCCHHEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC
WSQTPIEERASLLRRTADILERHMDELIAICIKEAGKIAQDGIDEVREAVDFCRYYAARA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
EELAEDDRLEPRGVVLCISPWNFPLAIFMGQVAAAIVTGNTVIAKPAEQTSLIALRALEL
HHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHEECCEEEECCCCHHHHHHHHHHHH
MESVGMPEGTVTAVIARGPAVGEALLEDERIKAVVFTGSTTTGTHISRILANRGGDQIPL
HHHCCCCCCCEEEEEECCCHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEE
IAETGGQNCMVVDSTALPEQVIDDVISSGFQSAGQRCSALRVLFLQEEIADGMTEMLIGA
EEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LKELHIGDPAQLSTDVGPVIDSKALNSLEAHVKDMENKAELLYECPVPENNGTFFAPRLY
HHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCEECCCHH
QIADISVLEREVFGPCVHIVRFKGDQLANTIEKINATGFGLTMGIHTRIEERAIELAKLS
HHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHH
RAGNVYINRNMIGAVVGVQPFGGTGLSGTGPKAGGPNYLSRFMNEKATPAPHQDDSVLGD
CCCCEEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
DKALISDKVSNLETLAFMKNAIKVEPEWRVTNLNDRISAVRQLLAQIAKVTIVEELADDF
CHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSTLAAARSQLISIEKKMRRPKALPGPTGESNVLYLEPRGILVCFADKNVTFEYWTLAIV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHH
TALATGNTVISVVSDLFYEEALAFRDKFNATGAPEGVLQVAKLCHLEALLEQDKLAGVVI
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
DSHSPRRTFMVRKLAEREGAILPVITSEYTDHLIQRLLTEKSISIDITASGGNTSLMTLV
ECCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEE
EEED
ECCC
>Mature Secondary Structure
MLFDGNLVADSTIRQKIRDFHRIDENLAVDHILPEAEVNMRARSRAWERARKMVLQIRRE
CEECCCEECHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QEGTGVVEALLNEYSLSSAEGVVLMCLAEALLRVPDKKTQDELIRDKLSKGKWSTHLGTS
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCC
NSLFVNASSWGLLLTGSMVNFSDTRKSNQFGLLKKTLGRMGEPVIRKAMNIAMKVMGEQF
CCEEEECCCCCEEEECCEECCHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCHH
VIGETIVAAVKRAEQKERNGYVYSYDVLGEGARTEKDAERYFQSYVKALVVIGEAAKGRG
HHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCC
PRKSPGISVKLSAIHPRYEFSHRDRVLKELPQKLKSLCLLAKKYDIGLTVDAEESERLDI
CCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEE
SLDIIEIVFSDPELSDWDGFGLAVQAYQKRAIFVIDWLRELTEKVGRKMMVRLVKGAYWD
EEEEEEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TEIKNAQKDGLEHYPVFTRKSSTDVSYHACANRLLDYRDTIYPQFATHNAYTASVIIELA
HHHCCHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCEEEEEEEEEE
GDDKEGFEFQCLHGMGDSLYDQIVTTDNIQCRIYAPVGQHEDLLAYLVRRLLENGANSSF
CCCCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHH
VNAIVDETRPVESLLEDPVEKTQRLKVTYNEQILKPIDLFGKERDNSKGLDLNDINQITP
HHHHHHCCCHHHHHHHCHHHHHHEEEEEECHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
LRESLDRWFNDHLLTSDQVPDDCFAVKNPADHNEIIGFHRHDSREEMVAKLEKAHNSFAT
HHHHHHHHHHCCCCCCCCCCCHHEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC
WSQTPIEERASLLRRTADILERHMDELIAICIKEAGKIAQDGIDEVREAVDFCRYYAARA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
EELAEDDRLEPRGVVLCISPWNFPLAIFMGQVAAAIVTGNTVIAKPAEQTSLIALRALEL
HHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHEECCEEEECCCCHHHHHHHHHHHH
MESVGMPEGTVTAVIARGPAVGEALLEDERIKAVVFTGSTTTGTHISRILANRGGDQIPL
HHHCCCCCCCEEEEEECCCHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEE
IAETGGQNCMVVDSTALPEQVIDDVISSGFQSAGQRCSALRVLFLQEEIADGMTEMLIGA
EEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LKELHIGDPAQLSTDVGPVIDSKALNSLEAHVKDMENKAELLYECPVPENNGTFFAPRLY
HHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCEECCCHH
QIADISVLEREVFGPCVHIVRFKGDQLANTIEKINATGFGLTMGIHTRIEERAIELAKLS
HHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHH
RAGNVYINRNMIGAVVGVQPFGGTGLSGTGPKAGGPNYLSRFMNEKATPAPHQDDSVLGD
CCCCEEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
DKALISDKVSNLETLAFMKNAIKVEPEWRVTNLNDRISAVRQLLAQIAKVTIVEELADDF
CHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSTLAAARSQLISIEKKMRRPKALPGPTGESNVLYLEPRGILVCFADKNVTFEYWTLAIV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHH
TALATGNTVISVVSDLFYEEALAFRDKFNATGAPEGVLQVAKLCHLEALLEQDKLAGVVI
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
DSHSPRRTFMVRKLAEREGAILPVITSEYTDHLIQRLLTEKSISIDITASGGNTSLMTLV
ECCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEE
EEED
ECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]