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The map label for this gene is cysJ [H]

Identifier: 119944057

GI number: 119944057

Start: 352591

End: 354813

Strand: Direct

Name: cysJ [H]

Synonym: Ping_0272

Alternate gene names: 119944057

Gene position: 352591-354813 (Clockwise)

Preceding gene: 119944056

Following gene: 119944058

Centisome position: 7.73

GC content: 46.51

Gene sequence:

>2223_bases
TTGCTACGTAAACTGCACTCTTATTTAGGTTTGGCGGCCAGTATATTGGTCGTTCTGTTGGCTATCAGCGGCGCTGTTCT
GGCGATAAATCCCGCTCTGGATCGCGCTCAAGCTAAGGTATCCGGCACTGACCAAATTAGCGTGGCGGATGTGGCGGCTA
ATATTGCCCGTTTCTACCCAAATGTAGAACAGCTGCAGCGTAAGGCTTCGGGCGGTCTTATTGTTTATTACAGTAATGCT
AATAAGGCGGGTGCGGATCTTGTTGATCCTTTTACGGGAGAAAAAATTGCAGCCTACTCCCTTTCTCCTTTTAAGCGCTG
GGTGCAAAATTTTCATCGATCGTTTTTGCTTGATACTCCCGGACGCGCGGCTGGCGGTATCGGTGCGCTGCTGATGGTTG
TTTTGAGTATTTCCGGCTTGTTTATGCTGCGTACACGGCAGGGCGGCTGGCGGAAAATTTTCCGGTCGATGCCGGGTTCG
ATTAAGCAGGATCTGCATGGTCACTTCTCGCGCTTTGCAGTATTGGGGTTAGTCCTTTCGGCCATTACTGGCGGTTATAT
GTCAGCGAACCGATTCGAGCTGATACCTGTCTATCAGCAGGTTGATCCTGCCTTTCCAGAAACAGTTAATGGCGGTAAAC
CCGCTGCTGTTGATGCGCTGCCTGCATTACAAGACATTGCATTTTCAGATCTTCGAGAGTTGGTTTATCCCTATGCGGGC
GACATCCGTGATGTTTATTCACTGCGCACTGATCAGGGTGTGGGGTTTATTGATCAGGCTACCGGAGAGCTGCTCTCTTA
TCAGATGTACGGGACGCCACAGAAAATTTATGAATTTATTTATATGCTACACACTGGCGAAGGGCTTTGGTGGCTGGCTT
TATTAGTTGGCCTCGCTTCATTCAGTGTGCCTTTGCTTGCCGTCACCGGCCTGCAAATATTTATGAAACGTCGACGCAGT
ATTATACGGATTAAGAATAATGCCACGGCAAACAGTGCCGATATAGTGATTTTAGTGGGCAGTGAAAGCAACAGTACCTG
GGGATTTGCGAAGACACTGCATGATGCCCTGAGTTTGTCGGGTTATCGCGTTCATAGTAACAGCATGAATAACATTGCCA
GTACTTACCCTAAAGCTAAGCAGATGTTTATTTTAACTTCTACTTATGGTGATGGTGACGCGCCCGCATCCGCGAAGTTA
TTTATGAATAAAATCAAGCGGTTTGCCAATAACCCTAACTTCCAGTTTTGCGTATTGGGATTTGGCGATCGTACGTTTGA
TAGTTATGGCCAATTTGCGCTTGATGTTAATAATGTATTGCTTAACAAGGGCTGGAATCCACTTACAAACATCGATATTA
TTGATAAACAATCAACACAGGCCTTTAATCGTTGGGGGACAGTGGTGGGATCCTTAATGGGCTTAGATCTTGACCTTATT
TATTGTCCTGTTCATCTTAATACGCAGTTATTACAGCTGGTGGATCGTGTCGATTACGGTGCTGAGGTTAATGCGCCAAC
TGCTATCCTGCGTTTTATCCCGGCGGAGAAAAAAACCGCTACATTTTTTAACAAAATACGCCGTAAACCCCGATTACCTC
AATTTTCTGCCGGAGATCTGGTGGGTATTTTACCGACAGAGTCAGACGGCGCGCGCTTTTATTCACTTGCCAGCGCATCG
AAAAATCGTCAGCTGGAAATTTGTGTGCATCAACATCCGCAGGGGATCTGTTCTAACTATCTTCATAAGCTGCAATTAGG
CGAGTGTATTAAAGGATTTATCCGGGAGAACCCCACTTTTCGTCCACGTCTCGAGCAAAGCTCTATTATTTTAATTGGGG
CGGGTACGGGGATCGCACCGCTGATTGGATTTATAAGGAATAATCACACTTGTCATCCAATGCGCCTGTATTGGGGAGGA
CGGGATCCAAACTCTGATTTTCTCTATCGGGCCGAGCTTGAACAATATTTGCAGGATAAGCGTTTAACCGAGTTAGTCAC
CGCATTTTCGCGCACTGAAGAGTCTTGTTATGTTCAGGATAAAGTGCTTGCCGACGCGCCAAAAATACAGGCATTAATTA
GTGAAGGAGCACAAATACTGGTGTGCGGTGGCCGGCCAATGAGTAAATGTGTCGCTGCTGCGATTACGAGGGTGATCTCA
CCATTGCAGATCACCTTACAAGATCTGAAAGAGCAGGGCCGTTATCTGGAAGATGTTTATTAA

Upstream 100 bases:

>100_bases
TGTGCCGCTTAGTAGTGAAGGAGCTGGTAAAGCAGTATCCGGTCGCGGTTATGTGAAAAGCTTCACTTATACTTTTAATT
AATAGGTTAGGAATCTGATT

Downstream 100 bases:

>100_bases
GTTCACCGGGATGTTTATAGCAATTTTACTTATCAGGTGATCTGTTTTTAAGGGGATGCCGATTAGAATATGGCGATCGG
TATATTCCAAAAGAACTAAA

Product: oxidoreductase FAD/NAD(P)-binding subunit

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 740; Mature: 740

Protein sequence:

>740_residues
MLRKLHSYLGLAASILVVLLAISGAVLAINPALDRAQAKVSGTDQISVADVAANIARFYPNVEQLQRKASGGLIVYYSNA
NKAGADLVDPFTGEKIAAYSLSPFKRWVQNFHRSFLLDTPGRAAGGIGALLMVVLSISGLFMLRTRQGGWRKIFRSMPGS
IKQDLHGHFSRFAVLGLVLSAITGGYMSANRFELIPVYQQVDPAFPETVNGGKPAAVDALPALQDIAFSDLRELVYPYAG
DIRDVYSLRTDQGVGFIDQATGELLSYQMYGTPQKIYEFIYMLHTGEGLWWLALLVGLASFSVPLLAVTGLQIFMKRRRS
IIRIKNNATANSADIVILVGSESNSTWGFAKTLHDALSLSGYRVHSNSMNNIASTYPKAKQMFILTSTYGDGDAPASAKL
FMNKIKRFANNPNFQFCVLGFGDRTFDSYGQFALDVNNVLLNKGWNPLTNIDIIDKQSTQAFNRWGTVVGSLMGLDLDLI
YCPVHLNTQLLQLVDRVDYGAEVNAPTAILRFIPAEKKTATFFNKIRRKPRLPQFSAGDLVGILPTESDGARFYSLASAS
KNRQLEICVHQHPQGICSNYLHKLQLGECIKGFIRENPTFRPRLEQSSIILIGAGTGIAPLIGFIRNNHTCHPMRLYWGG
RDPNSDFLYRAELEQYLQDKRLTELVTAFSRTEESCYVQDKVLADAPKIQALISEGAQILVCGGRPMSKCVAAAITRVIS
PLQITLQDLKEQGRYLEDVY

Sequences:

>Translated_740_residues
MLRKLHSYLGLAASILVVLLAISGAVLAINPALDRAQAKVSGTDQISVADVAANIARFYPNVEQLQRKASGGLIVYYSNA
NKAGADLVDPFTGEKIAAYSLSPFKRWVQNFHRSFLLDTPGRAAGGIGALLMVVLSISGLFMLRTRQGGWRKIFRSMPGS
IKQDLHGHFSRFAVLGLVLSAITGGYMSANRFELIPVYQQVDPAFPETVNGGKPAAVDALPALQDIAFSDLRELVYPYAG
DIRDVYSLRTDQGVGFIDQATGELLSYQMYGTPQKIYEFIYMLHTGEGLWWLALLVGLASFSVPLLAVTGLQIFMKRRRS
IIRIKNNATANSADIVILVGSESNSTWGFAKTLHDALSLSGYRVHSNSMNNIASTYPKAKQMFILTSTYGDGDAPASAKL
FMNKIKRFANNPNFQFCVLGFGDRTFDSYGQFALDVNNVLLNKGWNPLTNIDIIDKQSTQAFNRWGTVVGSLMGLDLDLI
YCPVHLNTQLLQLVDRVDYGAEVNAPTAILRFIPAEKKTATFFNKIRRKPRLPQFSAGDLVGILPTESDGARFYSLASAS
KNRQLEICVHQHPQGICSNYLHKLQLGECIKGFIRENPTFRPRLEQSSIILIGAGTGIAPLIGFIRNNHTCHPMRLYWGG
RDPNSDFLYRAELEQYLQDKRLTELVTAFSRTEESCYVQDKVLADAPKIQALISEGAQILVCGGRPMSKCVAAAITRVIS
PLQITLQDLKEQGRYLEDVY
>Mature_740_residues
MLRKLHSYLGLAASILVVLLAISGAVLAINPALDRAQAKVSGTDQISVADVAANIARFYPNVEQLQRKASGGLIVYYSNA
NKAGADLVDPFTGEKIAAYSLSPFKRWVQNFHRSFLLDTPGRAAGGIGALLMVVLSISGLFMLRTRQGGWRKIFRSMPGS
IKQDLHGHFSRFAVLGLVLSAITGGYMSANRFELIPVYQQVDPAFPETVNGGKPAAVDALPALQDIAFSDLRELVYPYAG
DIRDVYSLRTDQGVGFIDQATGELLSYQMYGTPQKIYEFIYMLHTGEGLWWLALLVGLASFSVPLLAVTGLQIFMKRRRS
IIRIKNNATANSADIVILVGSESNSTWGFAKTLHDALSLSGYRVHSNSMNNIASTYPKAKQMFILTSTYGDGDAPASAKL
FMNKIKRFANNPNFQFCVLGFGDRTFDSYGQFALDVNNVLLNKGWNPLTNIDIIDKQSTQAFNRWGTVVGSLMGLDLDLI
YCPVHLNTQLLQLVDRVDYGAEVNAPTAILRFIPAEKKTATFFNKIRRKPRLPQFSAGDLVGILPTESDGARFYSLASAS
KNRQLEICVHQHPQGICSNYLHKLQLGECIKGFIRENPTFRPRLEQSSIILIGAGTGIAPLIGFIRNNHTCHPMRLYWGG
RDPNSDFLYRAELEQYLQDKRLTELVTAFSRTEESCYVQDKVLADAPKIQALISEGAQILVCGGRPMSKCVAAAITRVIS
PLQITLQDLKEQGRYLEDVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI127139033, Length=224, Percent_Identity=32.1428571428571, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI10835173, Length=228, Percent_Identity=30.7017543859649, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI169790958, Length=158, Percent_Identity=36.0759493670886, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI169790956, Length=158, Percent_Identity=36.0759493670886, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI40254422, Length=187, Percent_Identity=32.620320855615, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI24041029, Length=257, Percent_Identity=29.1828793774319, Blast_Score=78, Evalue=4e-14,
Organism=Escherichia coli, GI1789123, Length=299, Percent_Identity=27.0903010033445, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17554134, Length=217, Percent_Identity=29.9539170506912, Blast_Score=105, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321832, Length=170, Percent_Identity=34.7058823529412, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6325305, Length=167, Percent_Identity=28.1437125748503, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24583543, Length=223, Percent_Identity=28.2511210762332, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI78706876, Length=223, Percent_Identity=28.2511210762332, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI78706872, Length=223, Percent_Identity=28.2511210762332, Blast_Score=71, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 81724; Mature: 81724

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRKLHSYLGLAASILVVLLAISGAVLAINPALDRAQAKVSGTDQISVADVAANIARFYP
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
NVEQLQRKASGGLIVYYSNANKAGADLVDPFTGEKIAAYSLSPFKRWVQNFHRSFLLDTP
CHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHEEECCC
GRAAGGIGALLMVVLSISGLFMLRTRQGGWRKIFRSMPGSIKQDLHGHFSRFAVLGLVLS
CCCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AITGGYMSANRFELIPVYQQVDPAFPETVNGGKPAAVDALPALQDIAFSDLRELVYPYAG
HHHCCCCCCCCEEEEECHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
DIRDVYSLRTDQGVGFIDQATGELLSYQMYGTPQKIYEFIYMLHTGEGLWWLALLVGLAS
CHHHHHHHHCCCCCCCHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FSVPLLAVTGLQIFMKRRRSIIRIKNNATANSADIVILVGSESNSTWGFAKTLHDALSLS
HHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCC
GYRVHSNSMNNIASTYPKAKQMFILTSTYGDGDAPASAKLFMNKIKRFANNPNFQFCVLG
CEEEECCCHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEE
FGDRTFDSYGQFALDVNNVLLNKGWNPLTNIDIIDKQSTQAFNRWGTVVGSLMGLDLDLI
CCCCCHHCCCCEEEEHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCEEEE
YCPVHLNTQLLQLVDRVDYGAEVNAPTAILRFIPAEKKTATFFNKIRRKPRLPQFSAGDL
EEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCE
VGILPTESDGARFYSLASASKNRQLEICVHQHPQGICSNYLHKLQLGECIKGFIRENPTF
EEEECCCCCCCCEEEEHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
RPRLEQSSIILIGAGTGIAPLIGFIRNNHTCHPMRLYWGGRDPNSDFLYRAELEQYLQDK
CCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHH
RLTELVTAFSRTEESCYVQDKVLADAPKIQALISEGAQILVCGGRPMSKCVAAAITRVIS
HHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHH
PLQITLQDLKEQGRYLEDVY
HHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MLRKLHSYLGLAASILVVLLAISGAVLAINPALDRAQAKVSGTDQISVADVAANIARFYP
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
NVEQLQRKASGGLIVYYSNANKAGADLVDPFTGEKIAAYSLSPFKRWVQNFHRSFLLDTP
CHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHEEECCC
GRAAGGIGALLMVVLSISGLFMLRTRQGGWRKIFRSMPGSIKQDLHGHFSRFAVLGLVLS
CCCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AITGGYMSANRFELIPVYQQVDPAFPETVNGGKPAAVDALPALQDIAFSDLRELVYPYAG
HHHCCCCCCCCEEEEECHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
DIRDVYSLRTDQGVGFIDQATGELLSYQMYGTPQKIYEFIYMLHTGEGLWWLALLVGLAS
CHHHHHHHHCCCCCCCHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FSVPLLAVTGLQIFMKRRRSIIRIKNNATANSADIVILVGSESNSTWGFAKTLHDALSLS
HHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCC
GYRVHSNSMNNIASTYPKAKQMFILTSTYGDGDAPASAKLFMNKIKRFANNPNFQFCVLG
CEEEECCCHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEE
FGDRTFDSYGQFALDVNNVLLNKGWNPLTNIDIIDKQSTQAFNRWGTVVGSLMGLDLDLI
CCCCCHHCCCCEEEEHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCEEEE
YCPVHLNTQLLQLVDRVDYGAEVNAPTAILRFIPAEKKTATFFNKIRRKPRLPQFSAGDL
EEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCE
VGILPTESDGARFYSLASASKNRQLEICVHQHPQGICSNYLHKLQLGECIKGFIRENPTF
EEEECCCCCCCCEEEEHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
RPRLEQSSIILIGAGTGIAPLIGFIRNNHTCHPMRLYWGGRDPNSDFLYRAELEQYLQDK
CCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHH
RLTELVTAFSRTEESCYVQDKVLADAPKIQALISEGAQILVCGGRPMSKCVAAAITRVIS
HHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHH
PLQITLQDLKEQGRYLEDVY
HHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA