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The map label for this gene is exeA [H]

Identifier: 119943964

GI number: 119943964

Start: 225135

End: 226889

Strand: Direct

Name: exeA [H]

Synonym: Ping_0177

Alternate gene names: 119943964

Gene position: 225135-226889 (Clockwise)

Preceding gene: 119943961

Following gene: 119943965

Centisome position: 4.94

GC content: 41.48

Gene sequence:

>1755_bases
ATGTATCAAGATTTTTTCTCTTTAAAAGAGCAACCCTTTTCGATCTCGCCTGATCCCGATTTTTTATTTTTGAGCAACCG
TCATCAAGAGGCAATAGCCCATTTGCAATATGGTGTTCAAGGTAACGGCGGGTTCGTCTTATTAACTGGTGAAGTGGGTA
CGGGAAAAACCACTGTCTGCCGTAAATTATTGCAGGAGATCGGTGCAACCACCGATATCGCTTTTATTTTAAACCCGGCT
TTAACTGATATTGAATTGCTGGCCACTGTCTGTGATGAATTTCATATTGATTATGAAAAAGATAAGATCAGTTTAAAATT
ATTATTTGACAGCTTAACCGCTTGGATGATGAATAACCATCATCAAGGACGGAGTGCGATTGTATTAATTGATGAAGCAC
AACATCTTAGCTTCTCGGTATTAGAGCAACTCCGTTTGCTCACCAATATTGAATCCAATAATAAAAAACCATTACAGGTC
ATTTTAATTGGCCAAACCGAGTTACAGCAAAAACTGAAGCAGCCTGAGTTGCGCCAATTGGCACAGCGAATTAGCGCACG
TTACCATCTGATGCCTTTGACGGAGCAGGAAAGCGTCTATTATATCCAGCATCGATTGAATGTTGCGGGGGTAAGTTTTC
CGATTTTTGAACACCGGGCAGTAAGAGAAGTTTTTAAGCGCAGTCAGGGAGTCCCGCGCTTAATTAATTTACTTTGTGAT
CGTAGCCTGCTCTGTGCATACACTCAAAATTCATTAAAAGTGACGGTGTTGATGGTAAAAAAAGCGAGTGATGAGATGGC
GCTTTCACCACCTCAAACACTTTTTAATGCGATCTTCAAAAGCAGTTGGCGATTTATTGCTTTGAGCCTATTGGCTGTCT
TCACTGCTTTTCAGGCTCCTGAACTGTTGAACCGCTTTAAAGAGGTCAAAGCACAACCGGCAGAATTAATCATACCAGCT
ATAGCTGCCACATTAGGTGAGTCTCTGCCAGAACTGATCGTGCCTCCGGAAGAACATATTACGCCTCTGCCAGAAAATAT
TGTGCCTCCCGAAGAGCTCATCGCGCCTCCCGCAGAATATACTGTGCCAACCGAATTGGAACAAGCCACCGAGGTTGGAG
TATTACAGAAGAATGAATCTCCTGACTGGTTTGATAATTATGAGTTATTAGATATTTCCAATGCAACCTTTGCTAATGCC
CTATTAAATTTATATGCTGTTTGGGGGTATCAGGTTGATCCCGAAACGGTTAATTGTGAACAGGGAAAAAGTGTGTTGTT
ATCCTGTTATTCGGAAAATACCAGCCTGAAAAAATTAAAGCAGTTGAATTACCCCAGTGTGGTTAGACTTGAAAGGGATA
ATTTAGAAAGTTTACATGCGGTGCTTTATGCCATTAATGACAGCTACCAATTATTGATTGACGGGCAAGTTATTGAGGTG
TCAGAAACCTGGTTTAACACCTACTGGTCAGGGGAGCTAACGGTACTTTGGCAGGCACCCTTTGAATTACAGGGTAACCT
TAAATTTGGCCAGCAAAGTGAGCAAATAGCCTGGCTGGCGAGGCAACTTAATAAGTTGCAGGGAATGCCGATTGAGAGTA
AAAATCGCTTCGATTTGCCATTATTACAGCAAGTGATGCGTTTTCAGATAGAAAATGGCTTAAAAGATGATGGTATTGTG
GGCGAGCGAACCTTAATACCACTAATGCAAATAGTTAATTCTCAGTTGCCACGACTACAACAGGAAGTAAATTAA

Upstream 100 bases:

>100_bases
GCCTCCAACTAAAAATATTTGCATTGTTTTTCCTCTTTATGTCTTAGTTAGTTATTATATGCAATAACTTCTCTTGTCAC
TATTTTCTTTGGATTTTGTT

Downstream 100 bases:

>100_bases
TGTCAACAATTCTAGCGGCACTGCAAAAGCAAAAATCATCACCAGGCGCTCATTTTATCCAACAACCAGAGGTTGAAAAA
GGACTGTTTAAATGGCGAGT

Product: general secretion pathway ATPase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MYQDFFSLKEQPFSISPDPDFLFLSNRHQEAIAHLQYGVQGNGGFVLLTGEVGTGKTTVCRKLLQEIGATTDIAFILNPA
LTDIELLATVCDEFHIDYEKDKISLKLLFDSLTAWMMNNHHQGRSAIVLIDEAQHLSFSVLEQLRLLTNIESNNKKPLQV
ILIGQTELQQKLKQPELRQLAQRISARYHLMPLTEQESVYYIQHRLNVAGVSFPIFEHRAVREVFKRSQGVPRLINLLCD
RSLLCAYTQNSLKVTVLMVKKASDEMALSPPQTLFNAIFKSSWRFIALSLLAVFTAFQAPELLNRFKEVKAQPAELIIPA
IAATLGESLPELIVPPEEHITPLPENIVPPEELIAPPAEYTVPTELEQATEVGVLQKNESPDWFDNYELLDISNATFANA
LLNLYAVWGYQVDPETVNCEQGKSVLLSCYSENTSLKKLKQLNYPSVVRLERDNLESLHAVLYAINDSYQLLIDGQVIEV
SETWFNTYWSGELTVLWQAPFELQGNLKFGQQSEQIAWLARQLNKLQGMPIESKNRFDLPLLQQVMRFQIENGLKDDGIV
GERTLIPLMQIVNSQLPRLQQEVN

Sequences:

>Translated_584_residues
MYQDFFSLKEQPFSISPDPDFLFLSNRHQEAIAHLQYGVQGNGGFVLLTGEVGTGKTTVCRKLLQEIGATTDIAFILNPA
LTDIELLATVCDEFHIDYEKDKISLKLLFDSLTAWMMNNHHQGRSAIVLIDEAQHLSFSVLEQLRLLTNIESNNKKPLQV
ILIGQTELQQKLKQPELRQLAQRISARYHLMPLTEQESVYYIQHRLNVAGVSFPIFEHRAVREVFKRSQGVPRLINLLCD
RSLLCAYTQNSLKVTVLMVKKASDEMALSPPQTLFNAIFKSSWRFIALSLLAVFTAFQAPELLNRFKEVKAQPAELIIPA
IAATLGESLPELIVPPEEHITPLPENIVPPEELIAPPAEYTVPTELEQATEVGVLQKNESPDWFDNYELLDISNATFANA
LLNLYAVWGYQVDPETVNCEQGKSVLLSCYSENTSLKKLKQLNYPSVVRLERDNLESLHAVLYAINDSYQLLIDGQVIEV
SETWFNTYWSGELTVLWQAPFELQGNLKFGQQSEQIAWLARQLNKLQGMPIESKNRFDLPLLQQVMRFQIENGLKDDGIV
GERTLIPLMQIVNSQLPRLQQEVN
>Mature_584_residues
MYQDFFSLKEQPFSISPDPDFLFLSNRHQEAIAHLQYGVQGNGGFVLLTGEVGTGKTTVCRKLLQEIGATTDIAFILNPA
LTDIELLATVCDEFHIDYEKDKISLKLLFDSLTAWMMNNHHQGRSAIVLIDEAQHLSFSVLEQLRLLTNIESNNKKPLQV
ILIGQTELQQKLKQPELRQLAQRISARYHLMPLTEQESVYYIQHRLNVAGVSFPIFEHRAVREVFKRSQGVPRLINLLCD
RSLLCAYTQNSLKVTVLMVKKASDEMALSPPQTLFNAIFKSSWRFIALSLLAVFTAFQAPELLNRFKEVKAQPAELIIPA
IAATLGESLPELIVPPEEHITPLPENIVPPEELIAPPAEYTVPTELEQATEVGVLQKNESPDWFDNYELLDISNATFANA
LLNLYAVWGYQVDPETVNCEQGKSVLLSCYSENTSLKKLKQLNYPSVVRLERDNLESLHAVLYAINDSYQLLIDGQVIEV
SETWFNTYWSGELTVLWQAPFELQGNLKFGQQSEQIAWLARQLNKLQGMPIESKNRFDLPLLQQVMRFQIENGLKDDGIV
GERTLIPLMQIVNSQLPRLQQEVN

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG3267

COG function: function code U; Type II secretory pathway, component ExeA (predicted ATPase)

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exeA family [H]

Homologues:

Organism=Escherichia coli, GI1789720, Length=196, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00004 AAA; PF01471 PG_binding_1 [H]

EC number: NA

Molecular weight: Translated: 66288; Mature: 66288

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQDFFSLKEQPFSISPDPDFLFLSNRHQEAIAHLQYGVQGNGGFVLLTGEVGTGKTTVC
CCCHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHCCEECCCCEEEEECCCCCCHHHHH
RKLLQEIGATTDIAFILNPALTDIELLATVCDEFHIDYEKDKISLKLLFDSLTAWMMNNH
HHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHCCC
HQGRSAIVLIDEAQHLSFSVLEQLRLLTNIESNNKKPLQVILIGQTELQQKLKQPELRQL
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCHHHHH
AQRISARYHLMPLTEQESVYYIQHRLNVAGVSFPIFEHRAVREVFKRSQGVPRLINLLCD
HHHHCCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHC
RSLLCAYTQNSLKVTVLMVKKASDEMALSPPQTLFNAIFKSSWRFIALSLLAVFTAFQAP
CCCEEEECCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCH
ELLNRFKEVKAQPAELIIPAIAATLGESLPELIVPPEEHITPLPENIVPPEELIAPPAEY
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHCCCCHHHCCCCCCCCCCCHHHCCCCCCC
TVPTELEQATEVGVLQKNESPDWFDNYELLDISNATFANALLNLYAVWGYQVDPETVNCE
CCCHHHHHHHHCCCEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCEEECCCCCCCC
QGKSVLLSCYSENTSLKKLKQLNYPSVVRLERDNLESLHAVLYAINDSYQLLIDGQVIEV
CCCEEEEEECCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHEECCCEEEEECCEEEEE
SETWFNTYWSGELTVLWQAPFELQGNLKFGQQSEQIAWLARQLNKLQGMPIESKNRFDLP
EHHHHHEEECCEEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LLQQVMRFQIENGLKDDGIVGERTLIPLMQIVNSQLPRLQQEVN
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYQDFFSLKEQPFSISPDPDFLFLSNRHQEAIAHLQYGVQGNGGFVLLTGEVGTGKTTVC
CCCHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHCCEECCCCEEEEECCCCCCHHHHH
RKLLQEIGATTDIAFILNPALTDIELLATVCDEFHIDYEKDKISLKLLFDSLTAWMMNNH
HHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHCCC
HQGRSAIVLIDEAQHLSFSVLEQLRLLTNIESNNKKPLQVILIGQTELQQKLKQPELRQL
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCHHHHH
AQRISARYHLMPLTEQESVYYIQHRLNVAGVSFPIFEHRAVREVFKRSQGVPRLINLLCD
HHHHCCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHC
RSLLCAYTQNSLKVTVLMVKKASDEMALSPPQTLFNAIFKSSWRFIALSLLAVFTAFQAP
CCCEEEECCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCH
ELLNRFKEVKAQPAELIIPAIAATLGESLPELIVPPEEHITPLPENIVPPEELIAPPAEY
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHCCCCHHHCCCCCCCCCCCHHHCCCCCCC
TVPTELEQATEVGVLQKNESPDWFDNYELLDISNATFANALLNLYAVWGYQVDPETVNCE
CCCHHHHHHHHCCCEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCEEECCCCCCCC
QGKSVLLSCYSENTSLKKLKQLNYPSVVRLERDNLESLHAVLYAINDSYQLLIDGQVIEV
CCCEEEEEECCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHEECCCEEEEECCEEEEE
SETWFNTYWSGELTVLWQAPFELQGNLKFGQQSEQIAWLARQLNKLQGMPIESKNRFDLP
EHHHHHEEECCEEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LLQQVMRFQIENGLKDDGIVGERTLIPLMQIVNSQLPRLQQEVN
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961440 [H]