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The map label for this gene is uxuA

Identifier: 119943926

GI number: 119943926

Start: 178308

End: 179492

Strand: Direct

Name: uxuA

Synonym: Ping_0136

Alternate gene names: 119943926

Gene position: 178308-179492 (Clockwise)

Preceding gene: 119943925

Following gene: 119943927

Centisome position: 3.91

GC content: 40.17

Gene sequence:

>1185_bases
ATGGAACAAACTTGGCGTTGGTATGGCCCAAATGATCCCGTATCGCTAAATGATATTCGTCAAGCAGGCGCAACGGGTAT
TGTTAATGGGTTGCATGATATCCCAAATGGGCAGGTGTGGGGTAAAAAAGCAATTTTAGCCCGTAAGGAAATTATTGAAG
GAAGTAGTTTAACTTGGTCGGTGGTTGAAAGTGTCCCTGTACATGAAGAGATTAAAACGCGTACAGGTAATTATGCAACA
TGGATTGAAAATTATAAGCAAACGCTTATTAATTTAGCTGAATGTGGGATTGACACTGTTTGCTATAACTTTATGCCGGT
GCTTGATTGGACACGGACTGATCTTGAATTTGAGATGGAAGATGGATCGCGCGCATTACGTTTTGATCAAATTGCTTTTG
CTGCATTTGAATTGCATATTCTTAAGCGTCCGAATGCAGAAAATGATTACAGCGCAGATGAGCAGCTTCAAGCTAAAGTC
TATTTTGATAATATGTCTGAGGCACAAATCGCCAAATTAACTGCGAATATTATTGCGGGTTTACCGGGTGCTGAAGAAGG
TTACACACTTGAGGAGTTCCAGGCGCAATTAGATCGTTATAAAGACATAGATAAAGAGACATTACGTAATAATTTAGCCT
TTTTTTTAAAAGAATTAATGCCAATTTGTGAATCATACGGGTTGAAATTGGCCATTCATCCAGATGATCCACCACGTCCT
ATTTTAGGCTTGCCACGTGTCGTTTCTACTATTGATGATATCAACTGGTTAACTACACAAGTACCAGAAAAAATGAACGG
TATCACGATGTGTACGGGCTCTTACGGTGTACGTGGTGATAATGATTTAGTGAATATGATCAAGCAGCATGGCGATCGAA
TTTACTTCACGCATCTACGTTCGACACAAAGAGAAAAAAATCAAAAGAGTTTCCATGAAGCAGCGCACCTTGGCGGTGAT
GTGGACATGTATAACGTTGTGATGGAATTACTCAGAGAAGAGCAGCGCCGTGAAAAATCAGGTAATATCCGTTTGATTCC
TATGCGTCCTGATCATGGTCACCAGATGCTTGATGATTTGAAAAAGAAAACCAATCCAGGTTATTCGGCTATAGGCCGTT
TAAAGGGATTGGCTGAAGTACGTGGTTTGGAAGTCGGTTTGAAACGCGCTTTTTTTAATAAATAA

Upstream 100 bases:

>100_bases
ATATAACTAAGTTTCGTGTAATAAGTGTTTTTAATTAATCGGCTGTCTCCTCAATAAATTTTTCTTGAGGAGAGCTGTTA
TAAATAATGAGGTAGTTGTA

Downstream 100 bases:

>100_bases
TTGCAAGTTATCTACCAATATAAATAAAAATCCGAACAAAGTCAGCCTCGGATTTTTATTTTCCTAGCAATCAATATAAT
CCTGTACTTATTCTGTTCTG

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MEQTWRWYGPNDPVSLNDIRQAGATGIVNGLHDIPNGQVWGKKAILARKEIIEGSSLTWSVVESVPVHEEIKTRTGNYAT
WIENYKQTLINLAECGIDTVCYNFMPVLDWTRTDLEFEMEDGSRALRFDQIAFAAFELHILKRPNAENDYSADEQLQAKV
YFDNMSEAQIAKLTANIIAGLPGAEEGYTLEEFQAQLDRYKDIDKETLRNNLAFFLKELMPICESYGLKLAIHPDDPPRP
ILGLPRVVSTIDDINWLTTQVPEKMNGITMCTGSYGVRGDNDLVNMIKQHGDRIYFTHLRSTQREKNQKSFHEAAHLGGD
VDMYNVVMELLREEQRREKSGNIRLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGLEVGLKRAFFNK

Sequences:

>Translated_394_residues
MEQTWRWYGPNDPVSLNDIRQAGATGIVNGLHDIPNGQVWGKKAILARKEIIEGSSLTWSVVESVPVHEEIKTRTGNYAT
WIENYKQTLINLAECGIDTVCYNFMPVLDWTRTDLEFEMEDGSRALRFDQIAFAAFELHILKRPNAENDYSADEQLQAKV
YFDNMSEAQIAKLTANIIAGLPGAEEGYTLEEFQAQLDRYKDIDKETLRNNLAFFLKELMPICESYGLKLAIHPDDPPRP
ILGLPRVVSTIDDINWLTTQVPEKMNGITMCTGSYGVRGDNDLVNMIKQHGDRIYFTHLRSTQREKNQKSFHEAAHLGGD
VDMYNVVMELLREEQRREKSGNIRLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGLEVGLKRAFFNK
>Mature_394_residues
MEQTWRWYGPNDPVSLNDIRQAGATGIVNGLHDIPNGQVWGKKAILARKEIIEGSSLTWSVVESVPVHEEIKTRTGNYAT
WIENYKQTLINLAECGIDTVCYNFMPVLDWTRTDLEFEMEDGSRALRFDQIAFAAFELHILKRPNAENDYSADEQLQAKV
YFDNMSEAQIAKLTANIIAGLPGAEEGYTLEEFQAQLDRYKDIDKETLRNNLAFFLKELMPICESYGLKLAIHPDDPPRP
ILGLPRVVSTIDDINWLTTQVPEKMNGITMCTGSYGVRGDNDLVNMIKQHGDRIYFTHLRSTQREKNQKSFHEAAHLGGD
VDMYNVVMELLREEQRREKSGNIRLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGLEVGLKRAFFNK

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family

Homologues:

Organism=Escherichia coli, GI1790778, Length=394, Percent_Identity=70.3045685279188, Blast_Score=599, Evalue=1e-173,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXUA_PSYIN (A1SR92)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941606.1
- ProteinModelPortal:   A1SR92
- SMR:   A1SR92
- STRING:   A1SR92
- GeneID:   4626047
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0136
- eggNOG:   COG1312
- HOGENOM:   HBG585927
- OMA:   VHEEIKT
- PhylomeDB:   A1SR92
- ProtClustDB:   PRK03906
- BioCyc:   PING357804:PING_0136-MONOMER
- HAMAP:   MF_00106
- InterPro:   IPR004628
- InterPro:   IPR013022
- Gene3D:   G3DSA:3.20.20.150
- PIRSF:   PIRSF016049
- TIGRFAMs:   TIGR00695

Pfam domain/function: PF03786 UxuA; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =4.2.1.8

Molecular weight: Translated: 44889; Mature: 44889

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTWRWYGPNDPVSLNDIRQAGATGIVNGLHDIPNGQVWGKKAILARKEIIEGSSLTWS
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHH
VVESVPVHEEIKTRTGNYATWIENYKQTLINLAECGIDTVCYNFMPVLDWTRTDLEFEME
HHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEEC
DGSRALRFDQIAFAAFELHILKRPNAENDYSADEQLQAKVYFDNMSEAQIAKLTANIIAG
CCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHEEEEEEECCCCHHHHHHHHHHHHHC
LPGAEEGYTLEEFQAQLDRYKDIDKETLRNNLAFFLKELMPICESYGLKLAIHPDDPPRP
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
ILGLPRVVSTIDDINWLTTQVPEKMNGITMCTGSYGVRGDNDLVNMIKQHGDRIYFTHLR
CCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEHH
STQREKNQKSFHEAAHLGGDVDMYNVVMELLREEQRREKSGNIRLIPMRPDHGHQMLDDL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
KKKTNPGYSAIGRLKGLAEVRGLEVGLKRAFFNK
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEQTWRWYGPNDPVSLNDIRQAGATGIVNGLHDIPNGQVWGKKAILARKEIIEGSSLTWS
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHH
VVESVPVHEEIKTRTGNYATWIENYKQTLINLAECGIDTVCYNFMPVLDWTRTDLEFEME
HHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEEC
DGSRALRFDQIAFAAFELHILKRPNAENDYSADEQLQAKVYFDNMSEAQIAKLTANIIAG
CCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHEEEEEEECCCCHHHHHHHHHHHHHC
LPGAEEGYTLEEFQAQLDRYKDIDKETLRNNLAFFLKELMPICESYGLKLAIHPDDPPRP
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
ILGLPRVVSTIDDINWLTTQVPEKMNGITMCTGSYGVRGDNDLVNMIKQHGDRIYFTHLR
CCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEHH
STQREKNQKSFHEAAHLGGDVDMYNVVMELLREEQRREKSGNIRLIPMRPDHGHQMLDDL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
KKKTNPGYSAIGRLKGLAEVRGLEVGLKRAFFNK
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA