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The map label for this gene is metJ [H]

Identifier: 119943853

GI number: 119943853

Start: 80966

End: 81256

Strand: Reverse

Name: metJ [H]

Synonym: Ping_0060

Alternate gene names: 119943853

Gene position: 81256-80966 (Counterclockwise)

Preceding gene: 229358030

Following gene: 119943849

Centisome position: 1.78

GC content: 41.58

Gene sequence:

>291_bases
ATGTCGACGAAATGGAATGGTGAATATATCAGCCCTTATGCTGAACACGGTAAAAAAAGTGAGCAAGTAAAAAAAATAAC
AGTCTCTATCCCCACGAAAGTCCTTAAAATATTGACCGACGAGCGCACCCGTCGTCAAGTAAATAACTTGCGCCATGCCA
CTAACAGTGAGTTATTATGTGAAGCATTCTTACATGCGTACACTGGACAACCGCTGCCGGAAGATGGGGACCTTGATAAA
AATCAAGCCACAGGCATTCCGGAAAGCGTTAAAAAGTTAATGAAAAAATAG

Upstream 100 bases:

>100_bases
AAGAAAATGAGCCATAGACATCTAGCCCTCTTTACGTATAGATTGCCAAAATAAGCAACAAAAGGTAAAATAACCTTTCT
AGTTTTATGGGGTAATAAAG

Downstream 100 bases:

>100_bases
AAAATTAAACTGTGCAGATGATCAGCCTGCAATTCACTGCTTCTACGCAGTTTAACGCTTTATTTATGATTAACTTTGTT
GCAGCTGCCTGTATAAAAAT

Product: transcriptional repressor protein MetJ

Products: NA

Alternate protein names: Met regulon regulatory protein metJ [H]

Number of amino acids: Translated: 96; Mature: 95

Protein sequence:

>96_residues
MSTKWNGEYISPYAEHGKKSEQVKKITVSIPTKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAYTGQPLPEDGDLDK
NQATGIPESVKKLMKK

Sequences:

>Translated_96_residues
MSTKWNGEYISPYAEHGKKSEQVKKITVSIPTKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAYTGQPLPEDGDLDK
NQATGIPESVKKLMKK
>Mature_95_residues
STKWNGEYISPYAEHGKKSEQVKKITVSIPTKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAYTGQPLPEDGDLDKN
QATGIPESVKKLMKK

Specific function: This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis [H]

COG id: COG3060

COG function: function code KE; Transcriptional regulator of met regulon

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metJ family [H]

Homologues:

Organism=Escherichia coli, GI1790373, Length=94, Percent_Identity=79.7872340425532, Blast_Score=163, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002084
- InterPro:   IPR010985
- ProDom:   PD020365 [H]

Pfam domain/function: PF01340 MetJ [H]

EC number: NA

Molecular weight: Translated: 10895; Mature: 10763

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKWNGEYISPYAEHGKKSEQVKKITVSIPTKVLKILTDERTRRQVNNLRHATNSELLC
CCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHH
EAFLHAYTGQPLPEDGDLDKNQATGIPESVKKLMKK
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
STKWNGEYISPYAEHGKKSEQVKKITVSIPTKVLKILTDERTRRQVNNLRHATNSELLC
CCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHH
EAFLHAYTGQPLPEDGDLDKNQATGIPESVKKLMKK
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]