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The map label for this gene is argS

Identifier: 119943800

GI number: 119943800

Start: 10601

End: 12349

Strand: Reverse

Name: argS

Synonym: Ping_0006

Alternate gene names: 119943800

Gene position: 12349-10601 (Counterclockwise)

Preceding gene: 119943801

Following gene: 119943799

Centisome position: 0.27

GC content: 40.37

Gene sequence:

>1749_bases
ATGAAAGTGCATATCCAGCAACTACTCGAGCAAGCTATCGTTTGCCTTATAAAACAAGAAATTATTCCTGCGGATATCCA
GCCTCGCATCAATATTGATCGCACCAAAGATAAGTCCCACGGTGACTACGCAAATAATTTAGCATTAATGTTAGCAAAAC
CTGCCAAACAAAATCCCCGCCATCTTGCTGAACTGATTATTGCCAACATACCTGAATCGACGTTAGTTATAAAAATGGAA
ATAGCGGGACCTGGATTTATTAACTTTTTTATTAATCCTAATTTCCTCGAAAAACAGATTGATGGCGCTTATTTGGATAA
AAGATTAAATGTACAGATAGAAGCCAATCCGCAAACAATAGTAATAGATTATTCCTCGCCAAATCTGGCCAAAGAGATGC
ATGTTGGTCACCTGCGCTCATCTATTATTGGTGATGCGGTAGCGCGCACCTTAGAATTTAAAGGTAATAACGTTGTCCGT
CAGAACCATGTCGGTGATTGGGGCACTCAGTTTGGTATGTTGCTCGCTTACATGGAAGAATTACGAGCTAAAGGTGAGCC
CATTGAAAATAATCTGGCTAATTTAGAGATTTTTTATCGTGCTGCAAAAGGACGTTTTGATGAATCAGAAGATTTTGCAA
CCCGTGCACGACATTTAGTGGTTAAACTCCAGGGTGGCAATAAAGACTGTTTAAAACTGTGGGCAAAATTTAATGAAACC
AGTCTTTCACACTGCCAGGAAACCTATCAGCGTTTAGGTGTAAGCCTAACCCGTGCAGATGTCCGGGGAGAAAGTAGTTA
TAACGATCAGTTAGCGGTGGTTGTTGAAGATCTTGATAAACAGGGTTTATTACAACAAAGCCAAGGCGCTAAATGTGTCT
TTTTGGATAACTTTAAAAATAAAGAAGGCGACCCTTTACCTGTTATTATTCAAAAGAAAGATGGTGGTTTCCTCTATGCA
ACATCGGATCTCGCTGCGATGCGTTATCGCCAGAATGAACTTAATGCCGATCGCATTCTTTATTTTGTAGATGCCCGCCA
GGGTTTACACTTCCAGCAGGTTTTTGAAGTTGCCCGTTCAGCGGGTTTTGTTAATGAGAAAACATCTCTTGAACATATGC
CCTTCGGGACAGTAATGGGAGAAGATGGTCGCCCATTTAAAACCCGTTCAGGGGCGGTTGCCAAATTAGCGGATTTATTA
ACAGAAGCAGAAGTGCGTGCTTATGAATTAGTAAAAGAAAAAAACAAAGAGATGTCTGAACCAGAGCTTCGTCATATCGC
TTCCGTGGTGGGTATCTCTTCGGTTAAATATGCCGATCTTTCTAAAAATCGTACCAGTGATTACACTTTTAGTTTTGATA
GCATGTTAAGTTTTGAAGGTAATACCGCGCCGTATCTACTTTATGCATACACCCGTGTTGTTAGTATCTTTAATAAAGCG
GGAATTGAGATGGGCAGTGTCACTGCAGCGGTTTCTTTAACCCAAGAGAAAGAAATAGACTTGGCCAATAAACTGATTCA
ATTTAATGATATTATTGATCAAGTTGCTAAACAAGGTATGCCGCACTTTTTATGTTCATACTTGTTTGAATTAGCAGGAC
TCTTTTCAAGCTTTTATGAGGCTTGCCCTATTTTGATTGCCGAAACGGAAACACAAAAACAGAGCCGCCTGAAACTGGCT
GGATTAACCGCTAAAACGCTTAAGCAAGGTTTGTCATTACTGGGAATTAATACGCTGGAGCGCATGTAA

Upstream 100 bases:

>100_bases
CTCTCAAGTATTTATTTTAAAGCCCTTCCCCTAGTCTTCATCGCTTATAAACGGTAGAATCTGCGCTTATTATTGGCCCG
TATTAATTGGTGATTTATCT

Downstream 100 bases:

>100_bases
TCCATGGCAACCGAAAACAGACGAAAACCGGCTACTCCAAAAAAAGCCGTCGTGCGTAAACGCACGGCGGTAAAAAAAAC
AGCATCTAAAAAAGGGATTC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MKVHIQQLLEQAIVCLIKQEIIPADIQPRINIDRTKDKSHGDYANNLALMLAKPAKQNPRHLAELIIANIPESTLVIKME
IAGPGFINFFINPNFLEKQIDGAYLDKRLNVQIEANPQTIVIDYSSPNLAKEMHVGHLRSSIIGDAVARTLEFKGNNVVR
QNHVGDWGTQFGMLLAYMEELRAKGEPIENNLANLEIFYRAAKGRFDESEDFATRARHLVVKLQGGNKDCLKLWAKFNET
SLSHCQETYQRLGVSLTRADVRGESSYNDQLAVVVEDLDKQGLLQQSQGAKCVFLDNFKNKEGDPLPVIIQKKDGGFLYA
TSDLAAMRYRQNELNADRILYFVDARQGLHFQQVFEVARSAGFVNEKTSLEHMPFGTVMGEDGRPFKTRSGAVAKLADLL
TEAEVRAYELVKEKNKEMSEPELRHIASVVGISSVKYADLSKNRTSDYTFSFDSMLSFEGNTAPYLLYAYTRVVSIFNKA
GIEMGSVTAAVSLTQEKEIDLANKLIQFNDIIDQVAKQGMPHFLCSYLFELAGLFSSFYEACPILIAETETQKQSRLKLA
GLTAKTLKQGLSLLGINTLERM

Sequences:

>Translated_582_residues
MKVHIQQLLEQAIVCLIKQEIIPADIQPRINIDRTKDKSHGDYANNLALMLAKPAKQNPRHLAELIIANIPESTLVIKME
IAGPGFINFFINPNFLEKQIDGAYLDKRLNVQIEANPQTIVIDYSSPNLAKEMHVGHLRSSIIGDAVARTLEFKGNNVVR
QNHVGDWGTQFGMLLAYMEELRAKGEPIENNLANLEIFYRAAKGRFDESEDFATRARHLVVKLQGGNKDCLKLWAKFNET
SLSHCQETYQRLGVSLTRADVRGESSYNDQLAVVVEDLDKQGLLQQSQGAKCVFLDNFKNKEGDPLPVIIQKKDGGFLYA
TSDLAAMRYRQNELNADRILYFVDARQGLHFQQVFEVARSAGFVNEKTSLEHMPFGTVMGEDGRPFKTRSGAVAKLADLL
TEAEVRAYELVKEKNKEMSEPELRHIASVVGISSVKYADLSKNRTSDYTFSFDSMLSFEGNTAPYLLYAYTRVVSIFNKA
GIEMGSVTAAVSLTQEKEIDLANKLIQFNDIIDQVAKQGMPHFLCSYLFELAGLFSSFYEACPILIAETETQKQSRLKLA
GLTAKTLKQGLSLLGINTLERM
>Mature_582_residues
MKVHIQQLLEQAIVCLIKQEIIPADIQPRINIDRTKDKSHGDYANNLALMLAKPAKQNPRHLAELIIANIPESTLVIKME
IAGPGFINFFINPNFLEKQIDGAYLDKRLNVQIEANPQTIVIDYSSPNLAKEMHVGHLRSSIIGDAVARTLEFKGNNVVR
QNHVGDWGTQFGMLLAYMEELRAKGEPIENNLANLEIFYRAAKGRFDESEDFATRARHLVVKLQGGNKDCLKLWAKFNET
SLSHCQETYQRLGVSLTRADVRGESSYNDQLAVVVEDLDKQGLLQQSQGAKCVFLDNFKNKEGDPLPVIIQKKDGGFLYA
TSDLAAMRYRQNELNADRILYFVDARQGLHFQQVFEVARSAGFVNEKTSLEHMPFGTVMGEDGRPFKTRSGAVAKLADLL
TEAEVRAYELVKEKNKEMSEPELRHIASVVGISSVKYADLSKNRTSDYTFSFDSMLSFEGNTAPYLLYAYTRVVSIFNKA
GIEMGSVTAAVSLTQEKEIDLANKLIQFNDIIDQVAKQGMPHFLCSYLFELAGLFSSFYEACPILIAETETQKQSRLKLA
GLTAKTLKQGLSLLGINTLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=575, Percent_Identity=39.304347826087, Blast_Score=404, Evalue=1e-113,
Organism=Homo sapiens, GI197100773, Length=518, Percent_Identity=31.0810810810811, Blast_Score=219, Evalue=6e-57,
Organism=Escherichia coli, GI1788184, Length=583, Percent_Identity=52.8301886792453, Blast_Score=613, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI71985061, Length=604, Percent_Identity=37.7483443708609, Blast_Score=367, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71985068, Length=563, Percent_Identity=38.5435168738899, Blast_Score=358, Evalue=5e-99,
Organism=Caenorhabditis elegans, GI17532153, Length=502, Percent_Identity=26.0956175298805, Blast_Score=152, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6320548, Length=543, Percent_Identity=33.5174953959484, Blast_Score=265, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6321883, Length=573, Percent_Identity=27.7486910994764, Blast_Score=213, Evalue=6e-56,
Organism=Drosophila melanogaster, GI18859963, Length=602, Percent_Identity=37.375415282392, Blast_Score=386, Evalue=1e-107,
Organism=Drosophila melanogaster, GI28571570, Length=478, Percent_Identity=31.1715481171548, Blast_Score=190, Evalue=3e-48,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_PSYIN (A1SQW6)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941480.1
- ProteinModelPortal:   A1SQW6
- SMR:   A1SQW6
- STRING:   A1SQW6
- GeneID:   4625095
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0006
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- PhylomeDB:   A1SQW6
- ProtClustDB:   PRK01611
- BioCyc:   PING357804:PING_0006-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 65236; Mature: 65236

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVHIQQLLEQAIVCLIKQEIIPADIQPRINIDRTKDKSHGDYANNLALMLAKPAKQNPR
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCEEEEEECCCCCCHH
HLAELIIANIPESTLVIKMEIAGPGFINFFINPNFLEKQIDGAYLDKRLNVQIEANPQTI
HHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCHHHHHCCCHHHCCEEEEEEECCCCEE
VIDYSSPNLAKEMHVGHLRSSIIGDAVARTLEFKGNNVVRQNHVGDWGTQFGMLLAYMEE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCHHHHHHHHHHHHHH
LRAKGEPIENNLANLEIFYRAAKGRFDESEDFATRARHLVVKLQGGNKDCLKLWAKFNET
HHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHCEEEEEEECCCCHHHHHHHHHCCCC
SLSHCQETYQRLGVSLTRADVRGESSYNDQLAVVVEDLDKQGLLQQSQGAKCVFLDNFKN
HHHHHHHHHHHHCCEEEEHHCCCCCCCCCEEEEEEECCCHHCCHHHCCCCEEEEEECCCC
KEGDPLPVIIQKKDGGFLYATSDLAAMRYRQNELNADRILYFVDARQGLHFQQVFEVARS
CCCCCCEEEEEECCCCEEEEECHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHH
AGFVNEKTSLEHMPFGTVMGEDGRPFKTRSGAVAKLADLLTEAEVRAYELVKEKNKEMSE
CCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PELRHIASVVGISSVKYADLSKNRTSDYTFSFDSMLSFEGNTAPYLLYAYTRVVSIFNKA
HHHHHHHHHHHCCCEEECCCCCCCCCCEEEEHHHHEECCCCCCCCHHHHHHHHHHHHHHC
GIEMGSVTAAVSLTQEKEIDLANKLIQFNDIIDQVAKQGMPHFLCSYLFELAGLFSSFYE
CCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ACPILIAETETQKQSRLKLAGLTAKTLKQGLSLLGINTLERM
HCCEEEEECCHHHHHHHHHHCCCHHHHHCCHHHHCCHHHHCC
>Mature Secondary Structure
MKVHIQQLLEQAIVCLIKQEIIPADIQPRINIDRTKDKSHGDYANNLALMLAKPAKQNPR
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCEEEEEECCCCCCHH
HLAELIIANIPESTLVIKMEIAGPGFINFFINPNFLEKQIDGAYLDKRLNVQIEANPQTI
HHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCHHHHHCCCHHHCCEEEEEEECCCCEE
VIDYSSPNLAKEMHVGHLRSSIIGDAVARTLEFKGNNVVRQNHVGDWGTQFGMLLAYMEE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCHHHHHHHHHHHHHH
LRAKGEPIENNLANLEIFYRAAKGRFDESEDFATRARHLVVKLQGGNKDCLKLWAKFNET
HHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHCEEEEEEECCCCHHHHHHHHHCCCC
SLSHCQETYQRLGVSLTRADVRGESSYNDQLAVVVEDLDKQGLLQQSQGAKCVFLDNFKN
HHHHHHHHHHHHCCEEEEHHCCCCCCCCCEEEEEEECCCHHCCHHHCCCCEEEEEECCCC
KEGDPLPVIIQKKDGGFLYATSDLAAMRYRQNELNADRILYFVDARQGLHFQQVFEVARS
CCCCCCEEEEEECCCCEEEEECHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHH
AGFVNEKTSLEHMPFGTVMGEDGRPFKTRSGAVAKLADLLTEAEVRAYELVKEKNKEMSE
CCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PELRHIASVVGISSVKYADLSKNRTSDYTFSFDSMLSFEGNTAPYLLYAYTRVVSIFNKA
HHHHHHHHHHHCCCEEECCCCCCCCCCEEEEHHHHEECCCCCCCCHHHHHHHHHHHHHHC
GIEMGSVTAAVSLTQEKEIDLANKLIQFNDIIDQVAKQGMPHFLCSYLFELAGLFSSFYE
CCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ACPILIAETETQKQSRLKLAGLTAKTLKQGLSLLGINTLERM
HCCEEEEECCHHHHHHHHHHCCCHHHHHCCHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA