Click here to switch to the map view.

The map label for this gene is kefC [C]

Identifier: 119900204

GI number: 119900204

Start: 4294332

End: 4295636

Strand: Direct

Name: kefC [C]

Synonym: azo3915

Alternate gene names: 119900204

Gene position: 4294332-4295636 (Clockwise)

Preceding gene: 119900203

Following gene: 119900205

Centisome position: 98.13

GC content: 68.28

Gene sequence:

>1305_bases
ATGAGCACCGCGGCCAACGCACTGCACGCGGTGAGCGTGCACAAGACCGAAGCGCTGCTGTTCTTCACGCTGCTGCAGCT
CGCGATCATCATCCTCGCGGCGCGCGCCGGCGGCGAGCTGGCGACGCGCCTCGGGCAGTCGTCCGCGGTCGGCGAGATCA
TCACCGGCATCCTGCTCGGGCCCTCGCTGTTCGGCTGGGTGGCGCCGGACCTGTTCGGCCAGGTGTTCCGCAGCGCACCG
CCGGAGCCGATGCAGATCCTGTCGCAGATCGGCCTGCTGCTGCTGATGTTCCAGATCGGCCTGGAGTTCGATTTCGGCCA
CCTCACCGATCGCAAGCACCGCCGCACCGTGGTGTGGGTGGCCAGTGCCGGGCTGGTGCTGCCGTTCGGCTTCGGCTTCG
GCCTCGGCTGGTTCGCCACCGGGCTGATGCCGGCCAGCGTCGAACCGCTGGCGAGCGGGCTGTTCGTTGCCACCGCGTTC
TCGATCACCGCGCTGCCCATCCTCGGCCGCATCATGATGGAGTTCCAGCTCACGCGGACCGCGCTCGGCGTGATCGCGAT
CAGCGCCGCGGCGATCAACGACGTGGTCGGCTGGCTGCTGCTCGCGCTCGTCTCGACGCTGGCGGTGTCGCACTTCGAGC
CGGCCGCATTCGCCACCAAGGTGGCGCTGGTGGGGGTGTTCTTCGCGGTCAGCTGGTTCGTCGTGCGTCCGCTCGCCAAG
CGCATGGTGGCGCTCGCCCAGCCTAACCGGGGGCGCTTGTCGCCCAACCTGCTGGGCGCGGTGCTGGCGCTGATCTTCGC
CGCCGGCATGACCACCTACCAGCTCGGCATCTTCGCGATCTTCGGCGGCTTCATGATGGGCGTGATCCTGCATGACGAGC
ACGGCCTGCGCGAAGCCTGGAACACCCGCGTCGGCCACTTCGTCACGGTGTTCTTCCTGCCCATCTTCTTCACCTACACC
GGGCTGCGCACCGATGTCGGCAGCCTGGACAGCGCCGCCGACTGGGGCTGGTGCGCGCTGGTGGTGGCGCTCGCCACCGC
GGGCAAGTTCTGCGGCTCCTATCTCGCCGCCCGCCGTTGCGGCCTCGGCCATCACGAATCCGGCATCCTCGGCATCATGA
TGAACACCCGCGCGCTGATGGAGCTGGTGGTGATCAACGTCGGCTACGATCTTGGCGTGATCTCGCGCGAGATGTTCACG
ATGCTGGTGATCATGGCGATCTTCAGCACCGTGGTGACCACGCCCTGCCTGCGCCGCTGGCTGCCGCGCATCGGTCATCC
GCTGCCGAGCGTGGTGCGGGAGTGA

Upstream 100 bases:

>100_bases
GGCGGCCGCAGGAGGTGGCCGACCTGGTCGGCTTCCTCGCCTCGGAACAGGCGGGCTACATCACCGGGCAGATCATCTCG
ATCAACGGCGGGATGATCTG

Downstream 100 bases:

>100_bases
GGCTCGGCCAGCGGCTGCAGCAGCTAGAATGAACAACCCCAGCAATACGCAACACACGGCTTGAACGACACCGGCCACAC
CGGTGTCGACCTGCCTCTTC

Product: putative Na/H(+) antiporter

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: MjNapA [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSTAANALHAVSVHKTEALLFFTLLQLAIIILAARAGGELATRLGQSSAVGEIITGILLGPSLFGWVAPDLFGQVFRSAP
PEPMQILSQIGLLLLMFQIGLEFDFGHLTDRKHRRTVVWVASAGLVLPFGFGFGLGWFATGLMPASVEPLASGLFVATAF
SITALPILGRIMMEFQLTRTALGVIAISAAAINDVVGWLLLALVSTLAVSHFEPAAFATKVALVGVFFAVSWFVVRPLAK
RMVALAQPNRGRLSPNLLGAVLALIFAAGMTTYQLGIFAIFGGFMMGVILHDEHGLREAWNTRVGHFVTVFFLPIFFTYT
GLRTDVGSLDSAADWGWCALVVALATAGKFCGSYLAARRCGLGHHESGILGIMMNTRALMELVVINVGYDLGVISREMFT
MLVIMAIFSTVVTTPCLRRWLPRIGHPLPSVVRE

Sequences:

>Translated_434_residues
MSTAANALHAVSVHKTEALLFFTLLQLAIIILAARAGGELATRLGQSSAVGEIITGILLGPSLFGWVAPDLFGQVFRSAP
PEPMQILSQIGLLLLMFQIGLEFDFGHLTDRKHRRTVVWVASAGLVLPFGFGFGLGWFATGLMPASVEPLASGLFVATAF
SITALPILGRIMMEFQLTRTALGVIAISAAAINDVVGWLLLALVSTLAVSHFEPAAFATKVALVGVFFAVSWFVVRPLAK
RMVALAQPNRGRLSPNLLGAVLALIFAAGMTTYQLGIFAIFGGFMMGVILHDEHGLREAWNTRVGHFVTVFFLPIFFTYT
GLRTDVGSLDSAADWGWCALVVALATAGKFCGSYLAARRCGLGHHESGILGIMMNTRALMELVVINVGYDLGVISREMFT
MLVIMAIFSTVVTTPCLRRWLPRIGHPLPSVVRE
>Mature_433_residues
STAANALHAVSVHKTEALLFFTLLQLAIIILAARAGGELATRLGQSSAVGEIITGILLGPSLFGWVAPDLFGQVFRSAPP
EPMQILSQIGLLLLMFQIGLEFDFGHLTDRKHRRTVVWVASAGLVLPFGFGFGLGWFATGLMPASVEPLASGLFVATAFS
ITALPILGRIMMEFQLTRTALGVIAISAAAINDVVGWLLLALVSTLAVSHFEPAAFATKVALVGVFFAVSWFVVRPLAKR
MVALAQPNRGRLSPNLLGAVLALIFAAGMTTYQLGIFAIFGGFMMGVILHDEHGLREAWNTRVGHFVTVFFLPIFFTYTG
LRTDVGSLDSAADWGWCALVVALATAGKFCGSYLAARRCGLGHHESGILGIMMNTRALMELVVINVGYDLGVISREMFTM
LVIMAIFSTVVTTPCLRRWLPRIGHPLPSVVRE

Specific function: This is probably a Na(+)/H(+) antiporter [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=407, Percent_Identity=28.7469287469287, Blast_Score=184, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 46659; Mature: 46528

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAANALHAVSVHKTEALLFFTLLQLAIIILAARAGGELATRLGQSSAVGEIITGILLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHH
PSLFGWVAPDLFGQVFRSAPPEPMQILSQIGLLLLMFQIGLEFDFGHLTDRKHRRTVVWV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
ASAGLVLPFGFGFGLGWFATGLMPASVEPLASGLFVATAFSITALPILGRIMMEFQLTRT
ECCCCCEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGVIAISAAAINDVVGWLLLALVSTLAVSHFEPAAFATKVALVGVFFAVSWFVVRPLAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMVALAQPNRGRLSPNLLGAVLALIFAAGMTTYQLGIFAIFGGFMMGVILHDEHGLREAW
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
NTRVGHFVTVFFLPIFFTYTGLRTDVGSLDSAADWGWCALVVALATAGKFCGSYLAARRC
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GLGHHESGILGIMMNTRALMELVVINVGYDLGVISREMFTMLVIMAIFSTVVTTPCLRRW
CCCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPRIGHPLPSVVRE
HHHHCCCCHHHHCC
>Mature Secondary Structure 
STAANALHAVSVHKTEALLFFTLLQLAIIILAARAGGELATRLGQSSAVGEIITGILLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHH
PSLFGWVAPDLFGQVFRSAPPEPMQILSQIGLLLLMFQIGLEFDFGHLTDRKHRRTVVWV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
ASAGLVLPFGFGFGLGWFATGLMPASVEPLASGLFVATAFSITALPILGRIMMEFQLTRT
ECCCCCEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGVIAISAAAINDVVGWLLLALVSTLAVSHFEPAAFATKVALVGVFFAVSWFVVRPLAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMVALAQPNRGRLSPNLLGAVLALIFAAGMTTYQLGIFAIFGGFMMGVILHDEHGLREAW
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
NTRVGHFVTVFFLPIFFTYTGLRTDVGSLDSAADWGWCALVVALATAGKFCGSYLAARRC
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GLGHHESGILGIMMNTRALMELVVINVGYDLGVISREMFTMLVIMAIFSTVVTTPCLRRW
CCCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPRIGHPLPSVVRE
HHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]