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The map label for this gene is prpC [H]

Identifier: 119900174

GI number: 119900174

Start: 4259097

End: 4259867

Strand: Direct

Name: prpC [H]

Synonym: azo3885

Alternate gene names: 119900174

Gene position: 4259097-4259867 (Clockwise)

Preceding gene: 119900173

Following gene: 119900175

Centisome position: 97.33

GC content: 69.91

Gene sequence:

>771_bases
ATGCTCGACCTCCAGACCGCCTACATCTCCCGCATCGGCCGCCGCAAGCGCAACGAGGACGCCTGCGGCTACTGGACCTC
GCCGCAGGGCTGCTGCTGGATCGTCTCCGACGGCGCCGGCGGCCACGGCAGCGGCGACCGCGCCGCGCAGATCGTCGTCA
GCACCGTGCTGGAACGCTTTTCCGCCCATCCCGAAGTGAGCGAAGCCCACGCGATCGGCCTGCTCGAAGCGGCACAGGCC
GCGGTGATGGCCGAGAAGCACGCCAACCCGGGCGGCGACGACATGCACGCCACCGCGGCGCTGCTGCTGATCGACGCCGG
GCGCCGCGAGGCGGTGTGGTCGCACGTCGGCGACACCCGCATCTACCTGTTCCGCAACCGCGAGCTGATCCACCAGACGC
GCGACCACAGCCTGGTGCAAAGCATGATCGACGCCGGTTACGGCGACGCCGCGATGATCCGCACCCACCCCCAGCGCAGC
CTGCTGACCTCGGCGATCGGCAACGCCGACGACCTCGCGCTCAGCGTATCGGGCGCGCCGGTGGCGATCGCGCCGGGCGA
CGCCTTCCTGATCTGCAGCGACGGCTGGTGGGAGTACGTCGATGAAGCACGCATGGCGGCCGAACTCGGCGCCGGCGGTT
CGGCCACCGACTGGCTGGAGCGCATGGCGGCGGTGGTCGAAGCCCATGACAACCACCACAGCGATAACTACACTGCCGTC
GCGGTCAAGGCCTACCGCGCCGAAGACGAGATCACGGTGTTGCTGCCCTGA

Upstream 100 bases:

>100_bases
GAAGGCCTACGAGGCCCAGATCGACCAGTTGCAGCGCGAACGCGGCTGAGCGTCCTTCTCCCCCCACACACATCCTTACC
GAGCCCACAACGAGAACACG

Downstream 100 bases:

>100_bases
CGCCTCCCGACCCCGCGCCGCCTTCTTCCGCAGCCGCCGGCCCAGCCGGCAATGTCATACAGGACCGAAAACCATGAAAA
CCCGCCTTGCCCTCCTCCCG

Product: putative phosphoprotein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MLDLQTAYISRIGRRKRNEDACGYWTSPQGCCWIVSDGAGGHGSGDRAAQIVVSTVLERFSAHPEVSEAHAIGLLEAAQA
AVMAEKHANPGGDDMHATAALLLIDAGRREAVWSHVGDTRIYLFRNRELIHQTRDHSLVQSMIDAGYGDAAMIRTHPQRS
LLTSAIGNADDLALSVSGAPVAIAPGDAFLICSDGWWEYVDEARMAAELGAGGSATDWLERMAAVVEAHDNHHSDNYTAV
AVKAYRAEDEITVLLP

Sequences:

>Translated_256_residues
MLDLQTAYISRIGRRKRNEDACGYWTSPQGCCWIVSDGAGGHGSGDRAAQIVVSTVLERFSAHPEVSEAHAIGLLEAAQA
AVMAEKHANPGGDDMHATAALLLIDAGRREAVWSHVGDTRIYLFRNRELIHQTRDHSLVQSMIDAGYGDAAMIRTHPQRS
LLTSAIGNADDLALSVSGAPVAIAPGDAFLICSDGWWEYVDEARMAAELGAGGSATDWLERMAAVVEAHDNHHSDNYTAV
AVKAYRAEDEITVLLP
>Mature_256_residues
MLDLQTAYISRIGRRKRNEDACGYWTSPQGCCWIVSDGAGGHGSGDRAAQIVVSTVLERFSAHPEVSEAHAIGLLEAAQA
AVMAEKHANPGGDDMHATAALLLIDAGRREAVWSHVGDTRIYLFRNRELIHQTRDHSLVQSMIDAGYGDAAMIRTHPQRS
LLTSAIGNADDLALSVSGAPVAIAPGDAFLICSDGWWEYVDEARMAAELGAGGSATDWLERMAAVVEAHDNHHSDNYTAV
AVKAYRAEDEITVLLP

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 27530; Mature: 27530

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLQTAYISRIGRRKRNEDACGYWTSPQGCCWIVSDGAGGHGSGDRAAQIVVSTVLERF
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
SAHPEVSEAHAIGLLEAAQAAVMAEKHANPGGDDMHATAALLLIDAGRREAVWSHVGDTR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEEEECCCHHHHHHHCCCEE
IYLFRNRELIHQTRDHSLVQSMIDAGYGDAAMIRTHPQRSLLTSAIGNADDLALSVSGAP
EEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEECCCC
VAIAPGDAFLICSDGWWEYVDEARMAAELGAGGSATDWLERMAAVVEAHDNHHSDNYTAV
EEEECCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
AVKAYRAEDEITVLLP
EEEEEECCCCEEEEEC
>Mature Secondary Structure
MLDLQTAYISRIGRRKRNEDACGYWTSPQGCCWIVSDGAGGHGSGDRAAQIVVSTVLERF
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
SAHPEVSEAHAIGLLEAAQAAVMAEKHANPGGDDMHATAALLLIDAGRREAVWSHVGDTR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEEEECCCHHHHHHHCCCEE
IYLFRNRELIHQTRDHSLVQSMIDAGYGDAAMIRTHPQRSLLTSAIGNADDLALSVSGAP
EEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEECCCC
VAIAPGDAFLICSDGWWEYVDEARMAAELGAGGSATDWLERMAAVVEAHDNHHSDNYTAV
EEEECCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
AVKAYRAEDEITVLLP
EEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]