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The map label for this gene is acoR [H]

Identifier: 119900164

GI number: 119900164

Start: 4247215

End: 4249182

Strand: Direct

Name: acoR [H]

Synonym: azo3875

Alternate gene names: 119900164

Gene position: 4247215-4249182 (Clockwise)

Preceding gene: 119900163

Following gene: 119900165

Centisome position: 97.06

GC content: 70.93

Gene sequence:

>1968_bases
ATGCTGGCGCAATCCCAGCGCGAACACATCGACCATGTGCTCGCCGTATCACAGGCGGGCGAACCCGCCACCGACCCGAT
CCACCGCTCGTGGGTCCGCTGTGTGAACGACTACGGCCTCGACCCGAGCCGGCCGACCCGCGCGCATATCGTCGAACAGG
CCCGCCTGCGCGAGCACCAGGACCAGATCGAGGACTTCCTCGGCGTCGCCCGCACCGGCATGGAGCAGCTCTACAAGCGC
ATGGCCGGCATCGGCTACGTGCTGCTGCTGACCGACGCCCACGGCATCGCGGTGGACTTCATCGGCAACGACGCCTGGGC
GCGCGAGCTGAAGCACTCCGGCCTCTATCTCGGCGCCGACTGGAGCGAAACCCGTGCCGGCACCTGTGCGGTGGGCACCT
GCATCGTCGACAAGGCGCCGATCACCTGTCACCACACCGATCACTTCGACGCGTCGCACATCACGCTGACCTGTAATGCC
GCGCCGCTGTTCGACCCCACCGGCGGCTTCCTCGGCGTGCTCGACGTCTCGGCGCTGACCTCGCCGTCGCCGCGCGACAG
CCAGCATCTGGCGCTGCACATGGTGACGATGTATGCGCAGATGGTGGAGGACGCCAGCTTCCTGCGCTATTTCCGCGACC
GCTGGGTGCTGCGGCTGGGCTCGGCGTGGTCGATGGTCGATGTGTCGGGCGAGATCATGCTCGCCTTCGATGCCGATGGC
CTCATCGTCGGCGCCAACAGCGGCGCCCGGCGCGCACTGCGCCCGCTCGACGGCGTCACCGACACCCTGATCGGGCGCCC
GCTCGGCGAGGTTTTCCGCGAGGGCATGGACGCGATCTGGCGCATCGCCCGCGCCGGTTTTTCCGCCGACCGCACCGCGC
TGTCCACCAGCGGCGGCGAGGTCTATTACGGTGCCGTGCTGCAACCGCGCGTGGCCCCGCTGCGCCCGGCGCCCGCCGTC
GCCGCCACCCCGGCGGCGCCCGCGCTGGAGCGCCTCGCCGGCAACGACCCGCAGATGCAGCGCCTGATCGCACAGGCGTC
GCGGCTGGTGAACCGGCCGGTGAACATCCTGGTGCACGGCGAAACCGGCACCGGCAAGGAAGTGCTGGCGAAAGCGCTGC
ACGAATCCAGCAGCCGCGCCACCAAGCCCTTCGTCGCGGTCAATTGCGCGGCGATCCCGGAATCGCTGATCGAGAGCGAA
CTGTTCGGCTACACCGCCGGCACCTTCACCGGCGGGCGCAGCAAGGGCATGCGCGGGCTGATCCAGCAGGCCGACGGCGG
CACGCTGTTCCTCGACGAGATCGGCGACATGCCGCTGCACCTGCAGACCCGGCTGCTGCGCGTGCTGGCCGAGCGCGAGG
TGCTGCCGCTGGGCGCCGAGAAGCCGGTGCCGGTGAATCTCACCGTGGTCGCCGCCTCGCACCGCGACCTGCGCAAGCTG
ATCGCCGAAGGCAGCTTCCGCGAGGATCTCTACTACCGCCTGTGCGGCGCCATCCTGTACCTGCCGCCGCTGCGCGAACG
GCGCGACCGCGACTACCTGATCGACCGCCTGCTCGCGGCCGAAGGCGCGGAACTGGGCACCAGCGCCGCGCTGGACCCGG
CCGCGCGCGGCCTGCTGCTGGGCTACGACTGGCCCGGCAACGTGCGCCAGCTGCGCAATGTGCTGCGCTTCGCGCTGGCG
GTGTGCGATGGCGAGCACATCCTGCCGCAGGACCTGCCCGCCGAACTGATGGCGAGCGCACCGCAAGCGCCGTCACGCAC
GCCCGCCATCGCGACCGCGACCGCGGCCGTCACTGCGCCCGCGGCGGTCACCACGCCGGGCGCCGACCCGGTGCGCGGCG
AACTGGAGGCCGCGCTGCGCCGTCATCACTGGAACATCACCGCCGCCGCGGCCGAACTCGGCGTCTGCCGCGCGACCATC
TACCGGCAGATGAAACGCCACGGCATCGTGCCGCCCCATCTGCTGTAG

Upstream 100 bases:

>100_bases
CTTCGATCAAGACATGCAGAGACCGATCCACGGTCCGCGTCCGCGCGGCGGCAGCTCACCGGCATCCAGCGGTGACGACC
GGCCCGCAGGAGGAGACGAG

Downstream 100 bases:

>100_bases
CCGCCCGGCCCGAAAGCTGGCCCGGCATGCGACAAAAGTGACATGCCGGGCGATTCCTGCCTGCCCGCCGCGGGACGATT
GCCATAAAATGCAACGTCAT

Product: sigma-54-dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 655; Mature: 655

Protein sequence:

>655_residues
MLAQSQREHIDHVLAVSQAGEPATDPIHRSWVRCVNDYGLDPSRPTRAHIVEQARLREHQDQIEDFLGVARTGMEQLYKR
MAGIGYVLLLTDAHGIAVDFIGNDAWARELKHSGLYLGADWSETRAGTCAVGTCIVDKAPITCHHTDHFDASHITLTCNA
APLFDPTGGFLGVLDVSALTSPSPRDSQHLALHMVTMYAQMVEDASFLRYFRDRWVLRLGSAWSMVDVSGEIMLAFDADG
LIVGANSGARRALRPLDGVTDTLIGRPLGEVFREGMDAIWRIARAGFSADRTALSTSGGEVYYGAVLQPRVAPLRPAPAV
AATPAAPALERLAGNDPQMQRLIAQASRLVNRPVNILVHGETGTGKEVLAKALHESSSRATKPFVAVNCAAIPESLIESE
LFGYTAGTFTGGRSKGMRGLIQQADGGTLFLDEIGDMPLHLQTRLLRVLAEREVLPLGAEKPVPVNLTVVAASHRDLRKL
IAEGSFREDLYYRLCGAILYLPPLRERRDRDYLIDRLLAAEGAELGTSAALDPAARGLLLGYDWPGNVRQLRNVLRFALA
VCDGEHILPQDLPAELMASAPQAPSRTPAIATATAAVTAPAAVTTPGADPVRGELEAALRRHHWNITAAAAELGVCRATI
YRQMKRHGIVPPHLL

Sequences:

>Translated_655_residues
MLAQSQREHIDHVLAVSQAGEPATDPIHRSWVRCVNDYGLDPSRPTRAHIVEQARLREHQDQIEDFLGVARTGMEQLYKR
MAGIGYVLLLTDAHGIAVDFIGNDAWARELKHSGLYLGADWSETRAGTCAVGTCIVDKAPITCHHTDHFDASHITLTCNA
APLFDPTGGFLGVLDVSALTSPSPRDSQHLALHMVTMYAQMVEDASFLRYFRDRWVLRLGSAWSMVDVSGEIMLAFDADG
LIVGANSGARRALRPLDGVTDTLIGRPLGEVFREGMDAIWRIARAGFSADRTALSTSGGEVYYGAVLQPRVAPLRPAPAV
AATPAAPALERLAGNDPQMQRLIAQASRLVNRPVNILVHGETGTGKEVLAKALHESSSRATKPFVAVNCAAIPESLIESE
LFGYTAGTFTGGRSKGMRGLIQQADGGTLFLDEIGDMPLHLQTRLLRVLAEREVLPLGAEKPVPVNLTVVAASHRDLRKL
IAEGSFREDLYYRLCGAILYLPPLRERRDRDYLIDRLLAAEGAELGTSAALDPAARGLLLGYDWPGNVRQLRNVLRFALA
VCDGEHILPQDLPAELMASAPQAPSRTPAIATATAAVTAPAAVTTPGADPVRGELEAALRRHHWNITAAAAELGVCRATI
YRQMKRHGIVPPHLL
>Mature_655_residues
MLAQSQREHIDHVLAVSQAGEPATDPIHRSWVRCVNDYGLDPSRPTRAHIVEQARLREHQDQIEDFLGVARTGMEQLYKR
MAGIGYVLLLTDAHGIAVDFIGNDAWARELKHSGLYLGADWSETRAGTCAVGTCIVDKAPITCHHTDHFDASHITLTCNA
APLFDPTGGFLGVLDVSALTSPSPRDSQHLALHMVTMYAQMVEDASFLRYFRDRWVLRLGSAWSMVDVSGEIMLAFDADG
LIVGANSGARRALRPLDGVTDTLIGRPLGEVFREGMDAIWRIARAGFSADRTALSTSGGEVYYGAVLQPRVAPLRPAPAV
AATPAAPALERLAGNDPQMQRLIAQASRLVNRPVNILVHGETGTGKEVLAKALHESSSRATKPFVAVNCAAIPESLIESE
LFGYTAGTFTGGRSKGMRGLIQQADGGTLFLDEIGDMPLHLQTRLLRVLAEREVLPLGAEKPVPVNLTVVAASHRDLRKL
IAEGSFREDLYYRLCGAILYLPPLRERRDRDYLIDRLLAAEGAELGTSAALDPAARGLLLGYDWPGNVRQLRNVLRFALA
VCDGEHILPQDLPAELMASAPQAPSRTPAIATATAAVTAPAAVTTPGADPVRGELEAALRRHHWNITAAAAELGVCRATI
YRQMKRHGIVPPHLL

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=440, Percent_Identity=36.1363636363636, Blast_Score=253, Evalue=4e-68,
Organism=Escherichia coli, GI1790299, Length=330, Percent_Identity=42.4242424242424, Blast_Score=230, Evalue=3e-61,
Organism=Escherichia coli, GI1788550, Length=322, Percent_Identity=39.4409937888199, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI1790437, Length=329, Percent_Identity=39.5136778115502, Blast_Score=222, Evalue=6e-59,
Organism=Escherichia coli, GI1786524, Length=331, Percent_Identity=42.2960725075529, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI1788905, Length=328, Percent_Identity=39.3292682926829, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87082117, Length=322, Percent_Identity=40.6832298136646, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1789087, Length=324, Percent_Identity=37.037037037037, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI87082152, Length=338, Percent_Identity=38.4615384615385, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1787583, Length=335, Percent_Identity=34.3283582089552, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI87081872, Length=323, Percent_Identity=34.6749226006192, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI87081858, Length=658, Percent_Identity=23.7082066869301, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1789828, Length=249, Percent_Identity=34.9397590361446, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 70923; Mature: 70923

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAQSQREHIDHVLAVSQAGEPATDPIHRSWVRCVNDYGLDPSRPTRAHIVEQARLREHQ
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
DQIEDFLGVARTGMEQLYKRMAGIGYVLLLTDAHGIAVDFIGNDAWARELKHSGLYLGAD
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCHHHHHHHHHCCEEEECC
WSETRAGTCAVGTCIVDKAPITCHHTDHFDASHITLTCNAAPLFDPTGGFLGVLDVSALT
CCCCCCCCEEEEEEEECCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCEEEHEEHHHHC
SPSPRDSQHLALHMVTMYAQMVEDASFLRYFRDRWVLRLGSAWSMVDVSGEIMLAFDADG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCEEEEECCCC
LIVGANSGARRALRPLDGVTDTLIGRPLGEVFREGMDAIWRIARAGFSADRTALSTSGGE
EEEECCCCCHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC
VYYGAVLQPRVAPLRPAPAVAATPAAPALERLAGNDPQMQRLIAQASRLVNRPVNILVHG
EEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEC
ETGTGKEVLAKALHESSSRATKPFVAVNCAAIPESLIESELFGYTAGTFTGGRSKGMRGL
CCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
IQQADGGTLFLDEIGDMPLHLQTRLLRVLAEREVLPLGAEKPVPVNLTVVAASHRDLRKL
HHCCCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHHH
IAEGSFREDLYYRLCGAILYLPPLRERRDRDYLIDRLLAAEGAELGTSAALDPAARGLLL
HHCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCEEE
GYDWPGNVRQLRNVLRFALAVCDGEHILPQDLPAELMASAPQAPSRTPAIATATAAVTAP
EECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEHHHHHCCC
AAVTTPGADPVRGELEAALRRHHWNITAAAAELGVCRATIYRQMKRHGIVPPHLL
CEEECCCCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLAQSQREHIDHVLAVSQAGEPATDPIHRSWVRCVNDYGLDPSRPTRAHIVEQARLREHQ
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
DQIEDFLGVARTGMEQLYKRMAGIGYVLLLTDAHGIAVDFIGNDAWARELKHSGLYLGAD
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCHHHHHHHHHCCEEEECC
WSETRAGTCAVGTCIVDKAPITCHHTDHFDASHITLTCNAAPLFDPTGGFLGVLDVSALT
CCCCCCCCEEEEEEEECCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCEEEHEEHHHHC
SPSPRDSQHLALHMVTMYAQMVEDASFLRYFRDRWVLRLGSAWSMVDVSGEIMLAFDADG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCEEEEECCCC
LIVGANSGARRALRPLDGVTDTLIGRPLGEVFREGMDAIWRIARAGFSADRTALSTSGGE
EEEECCCCCHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC
VYYGAVLQPRVAPLRPAPAVAATPAAPALERLAGNDPQMQRLIAQASRLVNRPVNILVHG
EEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEC
ETGTGKEVLAKALHESSSRATKPFVAVNCAAIPESLIESELFGYTAGTFTGGRSKGMRGL
CCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
IQQADGGTLFLDEIGDMPLHLQTRLLRVLAEREVLPLGAEKPVPVNLTVVAASHRDLRKL
HHCCCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHHH
IAEGSFREDLYYRLCGAILYLPPLRERRDRDYLIDRLLAAEGAELGTSAALDPAARGLLL
HHCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCEEE
GYDWPGNVRQLRNVLRFALAVCDGEHILPQDLPAELMASAPQAPSRTPAIATATAAVTAP
EECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEHHHHHCCC
AAVTTPGADPVRGELEAALRRHHWNITAAAAELGVCRATIYRQMKRHGIVPPHLL
CEEECCCCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]