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The map label for this gene is glpR [H]

Identifier: 119900117

GI number: 119900117

Start: 4188333

End: 4189109

Strand: Direct

Name: glpR [H]

Synonym: azo3828

Alternate gene names: 119900117

Gene position: 4188333-4189109 (Clockwise)

Preceding gene: 119900116

Following gene: 119900118

Centisome position: 95.71

GC content: 69.37

Gene sequence:

>777_bases
ATGCTGCAAGAAGAACGCTACCAGCGCATCTGCGCCCTGCTCGAAACCTTCAAGAGCCTGTCGACCGAGCGCATTTCCGG
CGAACTCGACATCTCGCGCGAGACGGTGCGGCGCGACGTGATCGCGCTCGAGGCGATGGGCCGCCTGCGCCGGGTTCACG
GCGGGGTGGTGCTGGACAGCGCACGCAGCGAGGCACCCTTTGTCGAACGGCTGAAGGTGCGCGCCAAGGAGAAGCAGGCC
ATCGCGCGCGCCGCGGTCAAGCTGCTGCAGCCCGGCCACACGCTCTTCCTCGATGCCGGCAGCACCACGCTGGCACTGAC
CGAGGAACTGCTGACGCTGTCCGGCCTGACCATCGTCACCAACAGCATGGATATCGCGGTACGGATGGCGCAGGCCGGCG
AGAGCATGGGCCAGCGCCACGAAGTCATCGTGCTCGGCGGCCGGCTCGCACCCGGCATCGCCGCCACCTGCGGCGAGACC
ACGGTGAGCGAGATCCAGCGCTACCGCGCCGACTTCGCGCTGCTGTCGCCGGTGGCGGTCGATGCGCACAACGGCGCCAC
CAGTTTCGACCACGGCGAAGCCGGCGTCGCCCGCGCGATGGCCGAGCGCGCCGCCCACCGGGTCATCCTCGCCGACCACA
GCAAGATCGGCGAGAGCAGCCGGGTGAGCTACTGCCCGGTCGGCAGCATCGACACCTTGGTGACCGATGGCCGCGCCCGC
AAGCTCTCCGCCCTGGCCGAAATCGAGAAGGCCGGGCCCGAGGTTGTCGTCGCCTGA

Upstream 100 bases:

>100_bases
GGCGGTGGTCGGCACCGTGGCGCTGCTGCTGCACCGGCTGACAGCCGACCGCCCGGCGCGCGCCATCATCAAATAACAAG
GATTCCGGAGACCCTACCCA

Downstream 100 bases:

>100_bases
GAACGGCAAACGAGGAGGCCGCCATGTCCTACCGCCACACCCTCGACCATCACACCTGGGTCTTCGCCGACCTGCGCGAA
CTCATGGCCAAGGCCAGCCC

Product: putative glycerol-3-phosphate regulon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLQEERYQRICALLETFKSLSTERISGELDISRETVRRDVIALEAMGRLRRVHGGVVLDSARSEAPFVERLKVRAKEKQA
IARAAVKLLQPGHTLFLDAGSTTLALTEELLTLSGLTIVTNSMDIAVRMAQAGESMGQRHEVIVLGGRLAPGIAATCGET
TVSEIQRYRADFALLSPVAVDAHNGATSFDHGEAGVARAMAERAAHRVILADHSKIGESSRVSYCPVGSIDTLVTDGRAR
KLSALAEIEKAGPEVVVA

Sequences:

>Translated_258_residues
MLQEERYQRICALLETFKSLSTERISGELDISRETVRRDVIALEAMGRLRRVHGGVVLDSARSEAPFVERLKVRAKEKQA
IARAAVKLLQPGHTLFLDAGSTTLALTEELLTLSGLTIVTNSMDIAVRMAQAGESMGQRHEVIVLGGRLAPGIAATCGET
TVSEIQRYRADFALLSPVAVDAHNGATSFDHGEAGVARAMAERAAHRVILADHSKIGESSRVSYCPVGSIDTLVTDGRAR
KLSALAEIEKAGPEVVVA
>Mature_258_residues
MLQEERYQRICALLETFKSLSTERISGELDISRETVRRDVIALEAMGRLRRVHGGVVLDSARSEAPFVERLKVRAKEKQA
IARAAVKLLQPGHTLFLDAGSTTLALTEELLTLSGLTIVTNSMDIAVRMAQAGESMGQRHEVIVLGGRLAPGIAATCGET
TVSEIQRYRADFALLSPVAVDAHNGATSFDHGEAGVARAMAERAAHRVILADHSKIGESSRVSYCPVGSIDTLVTDGRAR
KLSALAEIEKAGPEVVVA

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=236, Percent_Identity=30.9322033898305, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1789059, Length=232, Percent_Identity=28.8793103448276, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1788069, Length=238, Percent_Identity=30.672268907563, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082344, Length=231, Percent_Identity=29.8701298701299, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789519, Length=256, Percent_Identity=28.90625, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI226510968, Length=237, Percent_Identity=27.4261603375527, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789170, Length=236, Percent_Identity=27.5423728813559, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787540, Length=212, Percent_Identity=30.6603773584906, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790635, Length=259, Percent_Identity=26.2548262548263, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790753, Length=236, Percent_Identity=24.5762711864407, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27709; Mature: 27709

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQEERYQRICALLETFKSLSTERISGELDISRETVRRDVIALEAMGRLRRVHGGVVLDS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEC
ARSEAPFVERLKVRAKEKQAIARAAVKLLQPGHTLFLDAGSTTLALTEELLTLSGLTIVT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEE
NSMDIAVRMAQAGESMGQRHEVIVLGGRLAPGIAATCGETTVSEIQRYRADFALLSPVAV
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCEEE
DAHNGATSFDHGEAGVARAMAERAAHRVILADHSKIGESSRVSYCPVGSIDTLVTDGRAR
ECCCCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCHH
KLSALAEIEKAGPEVVVA
HHHHHHHHHHCCCCEEEC
>Mature Secondary Structure
MLQEERYQRICALLETFKSLSTERISGELDISRETVRRDVIALEAMGRLRRVHGGVVLDS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEC
ARSEAPFVERLKVRAKEKQAIARAAVKLLQPGHTLFLDAGSTTLALTEELLTLSGLTIVT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEE
NSMDIAVRMAQAGESMGQRHEVIVLGGRLAPGIAATCGETTVSEIQRYRADFALLSPVAV
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCEEE
DAHNGATSFDHGEAGVARAMAERAAHRVILADHSKIGESSRVSYCPVGSIDTLVTDGRAR
ECCCCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCHH
KLSALAEIEKAGPEVVVA
HHHHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]