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The map label for this gene is dctB [H]

Identifier: 119899955

GI number: 119899955

Start: 4027103

End: 4028941

Strand: Direct

Name: dctB [H]

Synonym: azo3666

Alternate gene names: 119899955

Gene position: 4027103-4028941 (Clockwise)

Preceding gene: 119899954

Following gene: 119899956

Centisome position: 92.03

GC content: 70.15

Gene sequence:

>1839_bases
ATGACACGGCTGCTGCAGGCCGCGCGGGCGCTGCGCCCGGTACGGCGGCGCCTGCTGCTGTTCTTCCTGCCCTGGCTGGC
GATCTTCAGCATCGGCGTCCCGCTGGTATGGCAGGAGCTGAGACAGTCGCTGGAACAGCCGCTGCTGCGCGCGCAAGCCG
ACTTCCTCGACCAGGGCACCCAGATCCTCGGCCGCACCCTCGCAACCGTACGGCGCGACGCGACCTTCCTCGCCCAGATG
CTGGGCGGCGGGCTGGGCGATACGCCGGTAGCGACAAAGCTGCTGTACACCGTCACCACCAACGGCGGCAATTACGCCCA
GACCCGGTGGGTCGATGAACGCGGCGACGAACGCATCCGGATCGAGCTGCGTGACGGCCACGCCCGTATCGCGGGCGCGG
CCGAACTGCGCAACGAAGCGGGCGCGGCGTACTTCGTGGACGCAAGAACACTGACCGCCGATCAATTCCATGTCGCGGGC
TTCGGCACCGGGCTCCCCGGCGCGCCGACCACGCTGCCGCTGCTGCGAGCGGTCACGCCGGTCATGGACGGCGAACAGCG
CCGCGGCCTCGTCGTGCTCGATTATCAGGCGCAACGCCTGCTCGACCGGCTGGGCGGACTGGGCCGCACGCTGGACTTCA
ACACCTTCCTCGTCGACCACCAGGGCCGCTGGCTGATGCATCCGGGCAATGGCGACGCGCCGGCGGCGCTGCCCGTCGCG
CGCCCCGCGTTGTGGACACAGATCGGCGGTCAGGCGCGCGGACTCCACCGCGATCCCGACGGCATCTGGGCCCACGCCCG
GTTCTCGCCCGCGGAGGACGCCGACAACGGGCAGCGGGCCTGGACGCTGATCGTCCAGGTGCCCGAAGGCGTCCTAGCTC
CGGTGGAGTCGCGCTGGCTGCTGATGCTTGCGCTGCTCTCGGCGGTCGCGCTGATCGCCGCGTTCTGGCTGTCGGCCCGG
CTGGCGTGGTCGGTCCATCAGGTCGAAGCGCGCAGCGCCGAACTCGCCCGCGCCAATACGGAACTGGAACGCAACATCGT
CAATCTGCGTGCGCTGCAGGCGCAGCTTGCGCGGGCGGACAAACTCTCCTCGCTCGGCCTGATGGTGGCCGGCGTGGCGC
ACGAACTGAACACCCCGCTCGGCAGTGCGTTGATGGCGCTGAGCACCGCGCGCGAGGGCGTCGCGACGCTGGAGGCGCAG
ATCGGCACCGGGCTGCGCAAGTCGGACCTCACGAGCTTCCTCGCCACCAGCCACGAAGGACTGGAACTCGCCCACCGCGC
GGTGTCCCGCGCCGCCGACCTGGTGCGCCGCTTCAAACAGGTGGCGATAGACCGCACGACGATGGAGCGGCGCAGCTTCG
ATCTCGCCGAAGTCATCGTCGATACCGATCACCGGTTGCACCGATGGAATCCGGGTTCGCCCGTCAGCCTCGAACTGAAA
CTGGCGCCCGGCCTGCAGATGGAGAGCTACCCGGGCCCGCTCGGACAGGTCGTCACCAACCTGCTCGACAATGCGCTGAC
CCACGCCTTCCCGGAGCAGCGCCCCGGCGCGATCACGCTCGAAGCCGTGGCGGAAGGGCCGGACCACGTCCGCATCACGC
TCGCCGACAACGGCGTCGGCATCCCGGCGGATGCGATCGAGCGCGTCTTCGACCCCTTCTTCACGACCCGCCGCCACGCC
GGCGGCACCGGGCTCGGCCTGCACGTCACCCACCAGATCGTCACCGACCTGCTCGGCGGACAGATCGAGGTGGAAAGCCA
GCAGGGCGGAGCTTCCAGCGGCACCCGCTTCAGCCTGCTGCTGCCGCGCGTGGCACCGCCGCATGCACCGGCGCACTAG

Upstream 100 bases:

>100_bases
TGAAGACGCGCGGCTGCCACCACGCGCAAGGCTATCTGTTTGCCCGGCCCGAGCCGGTCGCCGGGCTGATCGCGCGCCTG
CAGTCCGGCCCGGCGCTGCA

Downstream 100 bases:

>100_bases
GGCAAGCGGCATTGCCTTCACCCCGGATTGGGATTAGCGTTGACCCACCTCACGGCGCCCGCGCGCTTGTCATAATCCAG
CAACGGAGGCAACAAAATGA

Product: putative sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 612; Mature: 611

Protein sequence:

>612_residues
MTRLLQAARALRPVRRRLLLFFLPWLAIFSIGVPLVWQELRQSLEQPLLRAQADFLDQGTQILGRTLATVRRDATFLAQM
LGGGLGDTPVATKLLYTVTTNGGNYAQTRWVDERGDERIRIELRDGHARIAGAAELRNEAGAAYFVDARTLTADQFHVAG
FGTGLPGAPTTLPLLRAVTPVMDGEQRRGLVVLDYQAQRLLDRLGGLGRTLDFNTFLVDHQGRWLMHPGNGDAPAALPVA
RPALWTQIGGQARGLHRDPDGIWAHARFSPAEDADNGQRAWTLIVQVPEGVLAPVESRWLLMLALLSAVALIAAFWLSAR
LAWSVHQVEARSAELARANTELERNIVNLRALQAQLARADKLSSLGLMVAGVAHELNTPLGSALMALSTAREGVATLEAQ
IGTGLRKSDLTSFLATSHEGLELAHRAVSRAADLVRRFKQVAIDRTTMERRSFDLAEVIVDTDHRLHRWNPGSPVSLELK
LAPGLQMESYPGPLGQVVTNLLDNALTHAFPEQRPGAITLEAVAEGPDHVRITLADNGVGIPADAIERVFDPFFTTRRHA
GGTGLGLHVTHQIVTDLLGGQIEVESQQGGASSGTRFSLLLPRVAPPHAPAH

Sequences:

>Translated_612_residues
MTRLLQAARALRPVRRRLLLFFLPWLAIFSIGVPLVWQELRQSLEQPLLRAQADFLDQGTQILGRTLATVRRDATFLAQM
LGGGLGDTPVATKLLYTVTTNGGNYAQTRWVDERGDERIRIELRDGHARIAGAAELRNEAGAAYFVDARTLTADQFHVAG
FGTGLPGAPTTLPLLRAVTPVMDGEQRRGLVVLDYQAQRLLDRLGGLGRTLDFNTFLVDHQGRWLMHPGNGDAPAALPVA
RPALWTQIGGQARGLHRDPDGIWAHARFSPAEDADNGQRAWTLIVQVPEGVLAPVESRWLLMLALLSAVALIAAFWLSAR
LAWSVHQVEARSAELARANTELERNIVNLRALQAQLARADKLSSLGLMVAGVAHELNTPLGSALMALSTAREGVATLEAQ
IGTGLRKSDLTSFLATSHEGLELAHRAVSRAADLVRRFKQVAIDRTTMERRSFDLAEVIVDTDHRLHRWNPGSPVSLELK
LAPGLQMESYPGPLGQVVTNLLDNALTHAFPEQRPGAITLEAVAEGPDHVRITLADNGVGIPADAIERVFDPFFTTRRHA
GGTGLGLHVTHQIVTDLLGGQIEVESQQGGASSGTRFSLLLPRVAPPHAPAH
>Mature_611_residues
TRLLQAARALRPVRRRLLLFFLPWLAIFSIGVPLVWQELRQSLEQPLLRAQADFLDQGTQILGRTLATVRRDATFLAQML
GGGLGDTPVATKLLYTVTTNGGNYAQTRWVDERGDERIRIELRDGHARIAGAAELRNEAGAAYFVDARTLTADQFHVAGF
GTGLPGAPTTLPLLRAVTPVMDGEQRRGLVVLDYQAQRLLDRLGGLGRTLDFNTFLVDHQGRWLMHPGNGDAPAALPVAR
PALWTQIGGQARGLHRDPDGIWAHARFSPAEDADNGQRAWTLIVQVPEGVLAPVESRWLLMLALLSAVALIAAFWLSARL
AWSVHQVEARSAELARANTELERNIVNLRALQAQLARADKLSSLGLMVAGVAHELNTPLGSALMALSTAREGVATLEAQI
GTGLRKSDLTSFLATSHEGLELAHRAVSRAADLVRRFKQVAIDRTTMERRSFDLAEVIVDTDHRLHRWNPGSPVSLELKL
APGLQMESYPGPLGQVVTNLLDNALTHAFPEQRPGAITLEAVAEGPDHVRITLADNGVGIPADAIERVFDPFFTTRRHAG
GTGLGLHVTHQIVTDLLGGQIEVESQQGGASSGTRFSLLLPRVAPPHAPAH

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=33.4645669291339, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693157, Length=268, Percent_Identity=29.1044776119403, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790861, Length=421, Percent_Identity=25.41567695962, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788549, Length=258, Percent_Identity=27.5193798449612, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48994928, Length=282, Percent_Identity=26.9503546099291, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66479; Mature: 66348

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLLQAARALRPVRRRLLLFFLPWLAIFSIGVPLVWQELRQSLEQPLLRAQADFLDQGT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QILGRTLATVRRDATFLAQMLGGGLGDTPVATKLLYTVTTNGGNYAQTRWVDERGDERIR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEEECCCCCEEHCCCCCCCCCCEEE
IELRDGHARIAGAAELRNEAGAAYFVDARTLTADQFHVAGFGTGLPGAPTTLPLLRAVTP
EEEECCCEEEHHHHHHHHCCCCEEEEECEEEECCCEEEEEECCCCCCCCHHHHHHHHHHH
VMDGEQRRGLVVLDYQAQRLLDRLGGLGRTLDFNTFLVDHQGRWLMHPGNGDAPAALPVA
HCCCCCCCCEEEECHHHHHHHHHHCCCCCEEECEEEEEECCCCEEECCCCCCCCCCCCCC
RPALWTQIGGQARGLHRDPDGIWAHARFSPAEDADNGQRAWTLIVQVPEGVLAPVESRWL
CHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHH
LMLALLSAVALIAAFWLSARLAWSVHQVEARSAELARANTELERNIVNLRALQAQLARAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLSSLGLMVAGVAHELNTPLGSALMALSTAREGVATLEAQIGTGLRKSDLTSFLATSHEG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCH
LELAHRAVSRAADLVRRFKQVAIDRTTMERRSFDLAEVIVDTDHRLHRWNPGSPVSLELK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEECCCCCCCEEEEEE
LAPGLQMESYPGPLGQVVTNLLDNALTHAFPEQRPGAITLEAVAEGPDHVRITLADNGVG
ECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECCCCC
IPADAIERVFDPFFTTRRHAGGTGLGLHVTHQIVTDLLGGQIEVESQQGGASSGTRFSLL
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEE
LPRVAPPHAPAH
ECCCCCCCCCCC
>Mature Secondary Structure 
TRLLQAARALRPVRRRLLLFFLPWLAIFSIGVPLVWQELRQSLEQPLLRAQADFLDQGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QILGRTLATVRRDATFLAQMLGGGLGDTPVATKLLYTVTTNGGNYAQTRWVDERGDERIR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEEECCCCCEEHCCCCCCCCCCEEE
IELRDGHARIAGAAELRNEAGAAYFVDARTLTADQFHVAGFGTGLPGAPTTLPLLRAVTP
EEEECCCEEEHHHHHHHHCCCCEEEEECEEEECCCEEEEEECCCCCCCCHHHHHHHHHHH
VMDGEQRRGLVVLDYQAQRLLDRLGGLGRTLDFNTFLVDHQGRWLMHPGNGDAPAALPVA
HCCCCCCCCEEEECHHHHHHHHHHCCCCCEEECEEEEEECCCCEEECCCCCCCCCCCCCC
RPALWTQIGGQARGLHRDPDGIWAHARFSPAEDADNGQRAWTLIVQVPEGVLAPVESRWL
CHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHH
LMLALLSAVALIAAFWLSARLAWSVHQVEARSAELARANTELERNIVNLRALQAQLARAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLSSLGLMVAGVAHELNTPLGSALMALSTAREGVATLEAQIGTGLRKSDLTSFLATSHEG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCH
LELAHRAVSRAADLVRRFKQVAIDRTTMERRSFDLAEVIVDTDHRLHRWNPGSPVSLELK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEECCCCCCCEEEEEE
LAPGLQMESYPGPLGQVVTNLLDNALTHAFPEQRPGAITLEAVAEGPDHVRITLADNGVG
ECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECCCCC
IPADAIERVFDPFFTTRRHAGGTGLGLHVTHQIVTDLLGGQIEVESQQGGASSGTRFSLL
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEE
LPRVAPPHAPAH
ECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]