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The map label for this gene is pta [H]

Identifier: 119899927

GI number: 119899927

Start: 3992536

End: 3993945

Strand: Direct

Name: pta [H]

Synonym: azo3638

Alternate gene names: 119899927

Gene position: 3992536-3993945 (Clockwise)

Preceding gene: 119899924

Following gene: 119899928

Centisome position: 91.24

GC content: 66.45

Gene sequence:

>1410_bases
ATGGAGCATGCGGCACAGCAGTTGATCCAGAACCGGACGTTCGACGAAATCCAGATCGGCGACTTCGCCCAGCTGTTGCG
CACCCTGCGCCCGGAAGACATCCACCTGTTTGCCGTGATGTCCGGCGACGTCAATCCCACCCACGTCGACCCCGAATTCG
CGCACTCCAGCCAGTTTCGCGAGGTCGTGGGCCACAGCATGTGGGGCAGCACGCTGATCTCCACCGTACTGGGCACCGAG
TTTCCCGGCCCGGGCACGGTCTATGTGTCGCAAAGCCTCAATTTCTGGCGCCCGGTCACCATCGGCGACACGCTGACCAT
CACCGTGACCTGCCGTGAGAAGTACCAGCACAACCACCACATCGTGTTCGACTGCGTGGCGCTGAACCAGGACGGCCTGA
AAGTCATCGACGGTACCGCCGAGGTCGCCGCGCCGACCGAAAAGGTGATGCGCAACCGCGTGGTACTGCCCGAGGTGACC
ATTTCCGATCGCGAACTGCGCTATCGCCACCTGCTCTCCATCACCGCCGGCCTTGCGCCGATTCCGATCGCGGTCGCGCA
CCCCTGCGACAAGGAGTCGCTCGGCGGGCCGATCCAGGCCGCACAGGCCGGGCTGGTCGCCCCCATCCTGGTCGGGCCGG
AAGCCAAGATTCGCGCGGTGGCGGAAGAGTTCGGCTACGACCTGAAGGGCCTGCGCATCGTCGACGTGGAGCACAGCCAC
GCATCGGCCGAGACCGCCGTGGCGCTGTGCCGTGACGGCGTCGCCGAGGCGCTGATGAAGGGCTCGCTGCATACCGACGA
GCTGATGAGCGAAGTGGTCTCGAAGGCCAACGGGCTGCGCACCTCGCGCCGTATCAGCCACGTCTTCCTCGCCGACGTGC
CGACCTACCCGCACCCGCTGATGATCACCGACGCCGCGATCAACATCGAGCCGACGCTGGAAGACAAGGTCCACATCATC
CAGAACGCGATCGACCTCGCCCAGGTGCTCGGCCTGCCGGAGCCCAAGGTCGCGATCCTGGCGGCGGTGGAAACCGTGAA
CCCCAAGATGCGCTCCACGCTGGAAGCCGCCGCGCTGTGCAAGATGGCTGACCGCGGCCAGATCAAGGGCGGCCTGCTCG
ACGGTCCGCTCGCCTTCGACAACGCGGTGTCGCTGGTCGCCGCCAAGACCAAGGGCATCCGCTCCGCGGTCGCCGGCAAC
GCCGACATCCTCGTGGTGCCCGACCTCGAATCCGGCAACATGGTGGCCAAGCAGCTCGAATACCTGGCCGATGCGCTGAT
GGCCGGCGTGGTGCTCGGCGCCCGCGTGCCCATCGTGCTGACCAGCCGCGCCGACACCGCCGAAACCCGCGCCGCTTCGT
GCGCGATCGCCCAGCTGATGGCGCACAAGAAGCGTGAGGCCAACAAATGA

Upstream 100 bases:

>100_bases
CCCGGACAGCATGCTGCGGCGCAAAATCCGCGGCGTGCGACACACAAGATTTCACCTATCTGCCGCTAGAATCCCCTTAT
CACGACGCAAAGGAGCAAAC

Downstream 100 bases:

>100_bases
AGGCCGTCCTCGTCCTCAATGCGGGCTCCAGCAGCCTGAAGTTCGCGCTGTTTCCGATCGAGCCGGCGCTCGCCGACCAC
GCCGCGCTGTCCGGCCAGGT

Product: bifunctional enoyl-CoA hydratase/phosphate acetyltransferase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MEHAAQQLIQNRTFDEIQIGDFAQLLRTLRPEDIHLFAVMSGDVNPTHVDPEFAHSSQFREVVGHSMWGSTLISTVLGTE
FPGPGTVYVSQSLNFWRPVTIGDTLTITVTCREKYQHNHHIVFDCVALNQDGLKVIDGTAEVAAPTEKVMRNRVVLPEVT
ISDRELRYRHLLSITAGLAPIPIAVAHPCDKESLGGPIQAAQAGLVAPILVGPEAKIRAVAEEFGYDLKGLRIVDVEHSH
ASAETAVALCRDGVAEALMKGSLHTDELMSEVVSKANGLRTSRRISHVFLADVPTYPHPLMITDAAINIEPTLEDKVHII
QNAIDLAQVLGLPEPKVAILAAVETVNPKMRSTLEAAALCKMADRGQIKGGLLDGPLAFDNAVSLVAAKTKGIRSAVAGN
ADILVVPDLESGNMVAKQLEYLADALMAGVVLGARVPIVLTSRADTAETRAASCAIAQLMAHKKREANK

Sequences:

>Translated_469_residues
MEHAAQQLIQNRTFDEIQIGDFAQLLRTLRPEDIHLFAVMSGDVNPTHVDPEFAHSSQFREVVGHSMWGSTLISTVLGTE
FPGPGTVYVSQSLNFWRPVTIGDTLTITVTCREKYQHNHHIVFDCVALNQDGLKVIDGTAEVAAPTEKVMRNRVVLPEVT
ISDRELRYRHLLSITAGLAPIPIAVAHPCDKESLGGPIQAAQAGLVAPILVGPEAKIRAVAEEFGYDLKGLRIVDVEHSH
ASAETAVALCRDGVAEALMKGSLHTDELMSEVVSKANGLRTSRRISHVFLADVPTYPHPLMITDAAINIEPTLEDKVHII
QNAIDLAQVLGLPEPKVAILAAVETVNPKMRSTLEAAALCKMADRGQIKGGLLDGPLAFDNAVSLVAAKTKGIRSAVAGN
ADILVVPDLESGNMVAKQLEYLADALMAGVVLGARVPIVLTSRADTAETRAASCAIAQLMAHKKREANK
>Mature_469_residues
MEHAAQQLIQNRTFDEIQIGDFAQLLRTLRPEDIHLFAVMSGDVNPTHVDPEFAHSSQFREVVGHSMWGSTLISTVLGTE
FPGPGTVYVSQSLNFWRPVTIGDTLTITVTCREKYQHNHHIVFDCVALNQDGLKVIDGTAEVAAPTEKVMRNRVVLPEVT
ISDRELRYRHLLSITAGLAPIPIAVAHPCDKESLGGPIQAAQAGLVAPILVGPEAKIRAVAEEFGYDLKGLRIVDVEHSH
ASAETAVALCRDGVAEALMKGSLHTDELMSEVVSKANGLRTSRRISHVFLADVPTYPHPLMITDAAINIEPTLEDKVHII
QNAIDLAQVLGLPEPKVAILAAVETVNPKMRSTLEAAALCKMADRGQIKGGLLDGPLAFDNAVSLVAAKTKGIRSAVAGN
ADILVVPDLESGNMVAKQLEYLADALMAGVVLGARVPIVLTSRADTAETRAASCAIAQLMAHKKREANK

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0280

COG function: function code C; Phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=276, Percent_Identity=29.3478260869565, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012147
- InterPro:   IPR002505 [H]

Pfam domain/function: PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 50413; Mature: 50413

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHAAQQLIQNRTFDEIQIGDFAQLLRTLRPEDIHLFAVMSGDVNPTHVDPEFAHSSQFR
CCHHHHHHHHCCCCCCEECCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
EVVGHSMWGSTLISTVLGTEFPGPGTVYVSQSLNFWRPVTIGDTLTITVTCREKYQHNHH
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEECCEEEEEEEEEHHHCCCCC
IVFDCVALNQDGLKVIDGTAEVAAPTEKVMRNRVVLPEVTISDRELRYRHLLSITAGLAP
EEEEEEEECCCCCEEECCCHHHCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
IPIAVAHPCDKESLGGPIQAAQAGLVAPILVGPEAKIRAVAEEFGYDLKGLRIVDVEHSH
CCEEEECCCCHHHCCCCHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCC
ASAETAVALCRDGVAEALMKGSLHTDELMSEVVSKANGLRTSRRISHVFLADVPTYPHPL
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHEEEEECCCCCCCCE
MITDAAINIEPTLEDKVHIIQNAIDLAQVLGLPEPKVAILAAVETVNPKMRSTLEAAALC
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCHHHHHHHHHHHHH
KMADRGQIKGGLLDGPLAFDNAVSLVAAKTKGIRSAVAGNADILVVPDLESGNMVAKQLE
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH
YLADALMAGVVLGARVPIVLTSRADTAETRAASCAIAQLMAHKKREANK
HHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEHAAQQLIQNRTFDEIQIGDFAQLLRTLRPEDIHLFAVMSGDVNPTHVDPEFAHSSQFR
CCHHHHHHHHCCCCCCEECCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
EVVGHSMWGSTLISTVLGTEFPGPGTVYVSQSLNFWRPVTIGDTLTITVTCREKYQHNHH
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEECCEEEEEEEEEHHHCCCCC
IVFDCVALNQDGLKVIDGTAEVAAPTEKVMRNRVVLPEVTISDRELRYRHLLSITAGLAP
EEEEEEEECCCCCEEECCCHHHCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
IPIAVAHPCDKESLGGPIQAAQAGLVAPILVGPEAKIRAVAEEFGYDLKGLRIVDVEHSH
CCEEEECCCCHHHCCCCHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCC
ASAETAVALCRDGVAEALMKGSLHTDELMSEVVSKANGLRTSRRISHVFLADVPTYPHPL
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHEEEEECCCCCCCCE
MITDAAINIEPTLEDKVHIIQNAIDLAQVLGLPEPKVAILAAVETVNPKMRSTLEAAALC
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCHHHHHHHHHHHHH
KMADRGQIKGGLLDGPLAFDNAVSLVAAKTKGIRSAVAGNADILVVPDLESGNMVAKQLE
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH
YLADALMAGVVLGARVPIVLTSRADTAETRAASCAIAQLMAHKKREANK
HHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]