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The map label for this gene is thrB [H]

Identifier: 119899893

GI number: 119899893

Start: 3958480

End: 3959433

Strand: Direct

Name: thrB [H]

Synonym: azo3604

Alternate gene names: 119899893

Gene position: 3958480-3959433 (Clockwise)

Preceding gene: 119899892

Following gene: 119899894

Centisome position: 90.46

GC content: 70.34

Gene sequence:

>954_bases
ATGTCCGTATTCACCTCCGTGTCCGACGCCGAACTCGCCCGCTGGCTACAGAACTACGCCATCGGCCGCCCGGTGGAGCT
GCGCGGCATCTCGGCCGGCGTGCAGAACAGCAACTTCTTCGTCACCACCACGCTGGGCCGTTACGTGCTGACGCTGTTCG
AAAGCATTCCGCGCGCCGAACTACCGTACTACCTTCACCTGATGGCCCACCTCGCGCGCCACGGTCTGCCGGTGCCGGCA
CCGATCGCCAACCGCGACAACGAATACCTCGACACCCTCAGCGAGCGCCCCGCGGTGCTGGTGATGCGCCTGCCGGGCGT
CTCGGTGATGGCGCCGGCGCTGCAGCACTGCGCCAAGGTCGGCGCGATGCTCGCCGGACTGCATCTTGCCGGCCAGTCCT
ACGGACGCCGCCAGGACAACCCGCGCGGCCCGGCCTGGCGAACTGCCACGGCCGAAGCGGTGAAGCGCTTCCTGCCCGCC
GCGGAGCAGCGCCTGCTCGACGACGAACTCGCGTTCCAGCGCGGCGTGGACCTCGCGGCGCTGCCGGCGGGCGCCATCCA
TGCCGACCTCTTCCGCGACAACGTGCTGTGGGATGGCGAGCACATCGGCGGCGTGATCGACTTCTACTTCGCGGGTTACG
ACGCCCTGCTGTTCGACGTCGCGGTCACCGTCAACGACTGGTGCACCGAGGCTGACGGCCAACTCGACCCGGCGCGCTGC
GCGGCGCTGCTCGCGGCCTACCACGCCGAACGCCCGTTCACCCCCGCCGAACACGCCGCCTGGCCCGGCGTGCTGCGCGC
CGCGGCGCTGCGTTTCTGGCTGTCGCGCGCGGCCGATTTCCATCTGCCGCGCGCCGGCGAGATGGTGCTGGTCAAGAACC
CGGACGAGTACCGCGACATCCTGCGCCTGCGCATCGCCGGCGTGCCCGCACTCGATTGCGGCGCGGGGCTTTGA

Upstream 100 bases:

>100_bases
ACGCCGCCCGCCCGCTCGCCGAAAAACTGTCGGCCTGGGAAGCGGTCAGAGCAGCAGCGTCGGCCCACCCATCCGCCTGA
ACCCGCGCCCGGAAAACACC

Downstream 100 bases:

>100_bases
GCTTGCGATGCCCATCGGCTAGCATCCGGCCTCCGTACCCGTCCGCCCCCGCGGCCGGACTGCTCGCCCGCCCCGTTTCC
AGGCCCTGCCGCCGATGACC

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSVFTSVSDAELARWLQNYAIGRPVELRGISAGVQNSNFFVTTTLGRYVLTLFESIPRAELPYYLHLMAHLARHGLPVPA
PIANRDNEYLDTLSERPAVLVMRLPGVSVMAPALQHCAKVGAMLAGLHLAGQSYGRRQDNPRGPAWRTATAEAVKRFLPA
AEQRLLDDELAFQRGVDLAALPAGAIHADLFRDNVLWDGEHIGGVIDFYFAGYDALLFDVAVTVNDWCTEADGQLDPARC
AALLAAYHAERPFTPAEHAAWPGVLRAAALRFWLSRAADFHLPRAGEMVLVKNPDEYRDILRLRIAGVPALDCGAGL

Sequences:

>Translated_317_residues
MSVFTSVSDAELARWLQNYAIGRPVELRGISAGVQNSNFFVTTTLGRYVLTLFESIPRAELPYYLHLMAHLARHGLPVPA
PIANRDNEYLDTLSERPAVLVMRLPGVSVMAPALQHCAKVGAMLAGLHLAGQSYGRRQDNPRGPAWRTATAEAVKRFLPA
AEQRLLDDELAFQRGVDLAALPAGAIHADLFRDNVLWDGEHIGGVIDFYFAGYDALLFDVAVTVNDWCTEADGQLDPARC
AALLAAYHAERPFTPAEHAAWPGVLRAAALRFWLSRAADFHLPRAGEMVLVKNPDEYRDILRLRIAGVPALDCGAGL
>Mature_316_residues
SVFTSVSDAELARWLQNYAIGRPVELRGISAGVQNSNFFVTTTLGRYVLTLFESIPRAELPYYLHLMAHLARHGLPVPAP
IANRDNEYLDTLSERPAVLVMRLPGVSVMAPALQHCAKVGAMLAGLHLAGQSYGRRQDNPRGPAWRTATAEAVKRFLPAA
EQRLLDDELAFQRGVDLAALPAGAIHADLFRDNVLWDGEHIGGVIDFYFAGYDALLFDVAVTVNDWCTEADGQLDPARCA
ALLAAYHAERPFTPAEHAAWPGVLRAAALRFWLSRAADFHLPRAGEMVLVKNPDEYRDILRLRIAGVPALDCGAGL

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 34717; Mature: 34586

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFTSVSDAELARWLQNYAIGRPVELRGISAGVQNSNFFVTTTLGRYVLTLFESIPRAE
CCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCCCC
LPYYLHLMAHLARHGLPVPAPIANRDNEYLDTLSERPAVLVMRLPGVSVMAPALQHCAKV
CCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHH
GAMLAGLHLAGQSYGRRQDNPRGPAWRTATAEAVKRFLPAAEQRLLDDELAFQRGVDLAA
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LPAGAIHADLFRDNVLWDGEHIGGVIDFYFAGYDALLFDVAVTVNDWCTEADGQLDPARC
CCCCHHHHHHHHCCCEECCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
AALLAAYHAERPFTPAEHAAWPGVLRAAALRFWLSRAADFHLPRAGEMVLVKNPDEYRDI
HHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHH
LRLRIAGVPALDCGAGL
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SVFTSVSDAELARWLQNYAIGRPVELRGISAGVQNSNFFVTTTLGRYVLTLFESIPRAE
CCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCCCC
LPYYLHLMAHLARHGLPVPAPIANRDNEYLDTLSERPAVLVMRLPGVSVMAPALQHCAKV
CCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHH
GAMLAGLHLAGQSYGRRQDNPRGPAWRTATAEAVKRFLPAAEQRLLDDELAFQRGVDLAA
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LPAGAIHADLFRDNVLWDGEHIGGVIDFYFAGYDALLFDVAVTVNDWCTEADGQLDPARC
CCCCHHHHHHHHCCCEECCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
AALLAAYHAERPFTPAEHAAWPGVLRAAALRFWLSRAADFHLPRAGEMVLVKNPDEYRDI
HHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHH
LRLRIAGVPALDCGAGL
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA