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The map label for this gene is tagO [H]

Identifier: 119899871

GI number: 119899871

Start: 3932553

End: 3933590

Strand: Reverse

Name: tagO [H]

Synonym: azo3582

Alternate gene names: 119899871

Gene position: 3933590-3932553 (Counterclockwise)

Preceding gene: 119899872

Following gene: 119899870

Centisome position: 89.89

GC content: 65.9

Gene sequence:

>1038_bases
GTGACGGCCGCGCTGCTCGGGCTTGCTCTTGGGGTCTCGCTCGCGGCGTGGCTGGGTACGGGATGGTTGCGGCGCTACGC
CCTTGCGCGCAGCTTGGTCGACGTTCCAAATGCCCGTAGCTCTCATTCCACTCCTACTCCGCGGGGCGGGGGCCTGGCGG
TCGTCCTGCCGTTCCTGGTGGTGATACTGCTGCTGGGGTGGGTGGGGCTGCTGCCAGCGGCTGAAGTGGCCGCCCTGCTG
GGGGCTGCCACCTTGGTAGCGGCCGTCGGCTTCCTGGATGATCATGGCCATGTCGCCGCGCGTTGGCGCCTACTGACCCA
CTTTGTTGCAGCTGCCTGGCTACTGGGGTGCGCCGGTATTCCCGCGTTCTCATCATTCGGGCTTTCTGCGGTGCCGATCC
AGATGCTCGCCGTCGTCGCAGCGCTCTATGTCGTTTGGGTTCTCAATCTGTACAACTTCATGGACGGTATCGACGGTATT
GCTGCCGTCGAAGGAATCGCGGTCGCAACGGGCGGAGCAGTCCTGGCGATAGCGGCCGGCCATCCGGTCGAGGTGATCGT
GCCGCCGCTGATGCTGGCCGCGGCGCTGGGAGGGTTCCTTGCGTGGAATTTCCCTCCAGCGCGGATATTCATGGGCGATG
TCGGTAGCGGTTTCGTAGGGGCGATGCTGGCCGCGTTTTCGCTGCAAGCGGGGCGCCACGACGAAGTGCTGTTCTGGTCC
TGGCTGATCCTGCTCGGTGTGTTCGTGGTGGACGCCACCTTCACGCTGCTGCGCCGCTTGCTGCGGGGCGAGCGCGTCTA
TCAGGCGCATCGGAGCCACGGCTACCAGCAGGCCGCGCGGCGTTGGAAGGCCCACCGCCCGGTCACCCTGGCCGTTGTGA
TGATCGATGTGTTCTGGCTGCTGCCAATTGCAGCCCTGGTGATTCTGGACTGGATGCCGCCGCTTCATGGCCTTGCTGTG
GCTTATGCACCGCTGCTCGTTGGTGCGCTTCTGCTGGGCGCGGGGCGGCGGGAGCCGACGGTCGGTCCCTCACTCTGA

Upstream 100 bases:

>100_bases
CGCTGCAAGTGGACATATCTTCCGCGCGCGAAACCTTGGGTTGGACTCCCCCCGTCGGCGTCGACGAGGGATTGCGTCGG
GCCGTGGCAGGAGAAGGACG

Downstream 100 bases:

>100_bases
CTCTCCCCCGCGTGTCGACCAGGGTGTCGGCTGCCATCGGGGAATTTGTCGCAATATGTTTGTCTGACGCCATTCTGCCG
CTGTGACGGTCCGCCGACGC

Product: cell envelope biogenesis membrane protein

Products: Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine; UMP [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTAALLGLALGVSLAAWLGTGWLRRYALARSLVDVPNARSSHSTPTPRGGGLAVVLPFLVVILLLGWVGLLPAAEVAALL
GAATLVAAVGFLDDHGHVAARWRLLTHFVAAAWLLGCAGIPAFSSFGLSAVPIQMLAVVAALYVVWVLNLYNFMDGIDGI
AAVEGIAVATGGAVLAIAAGHPVEVIVPPLMLAAALGGFLAWNFPPARIFMGDVGSGFVGAMLAAFSLQAGRHDEVLFWS
WLILLGVFVVDATFTLLRRLLRGERVYQAHRSHGYQQAARRWKAHRPVTLAVVMIDVFWLLPIAALVILDWMPPLHGLAV
AYAPLLVGALLLGAGRREPTVGPSL

Sequences:

>Translated_345_residues
MTAALLGLALGVSLAAWLGTGWLRRYALARSLVDVPNARSSHSTPTPRGGGLAVVLPFLVVILLLGWVGLLPAAEVAALL
GAATLVAAVGFLDDHGHVAARWRLLTHFVAAAWLLGCAGIPAFSSFGLSAVPIQMLAVVAALYVVWVLNLYNFMDGIDGI
AAVEGIAVATGGAVLAIAAGHPVEVIVPPLMLAAALGGFLAWNFPPARIFMGDVGSGFVGAMLAAFSLQAGRHDEVLFWS
WLILLGVFVVDATFTLLRRLLRGERVYQAHRSHGYQQAARRWKAHRPVTLAVVMIDVFWLLPIAALVILDWMPPLHGLAV
AYAPLLVGALLLGAGRREPTVGPSL
>Mature_344_residues
TAALLGLALGVSLAAWLGTGWLRRYALARSLVDVPNARSSHSTPTPRGGGLAVVLPFLVVILLLGWVGLLPAAEVAALLG
AATLVAAVGFLDDHGHVAARWRLLTHFVAAAWLLGCAGIPAFSSFGLSAVPIQMLAVVAALYVVWVLNLYNFMDGIDGIA
AVEGIAVATGGAVLAIAAGHPVEVIVPPLMLAAALGGFLAWNFPPARIFMGDVGSGFVGAMLAAFSLQAGRHDEVLFWSW
LILLGVFVVDATFTLLRRLLRGERVYQAHRSHGYQQAARRWKAHRPVTLAVVMIDVFWLLPIAALVILDWMPPLHGLAVA
YAPLLVGALLLGAGRREPTVGPSL

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.13 [C]

Molecular weight: Translated: 36348; Mature: 36216

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAALLGLALGVSLAAWLGTGWLRRYALARSLVDVPNARSSHSTPTPRGGGLAVVLPFLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
VILLLGWVGLLPAAEVAALLGAATLVAAVGFLDDHGHVAARWRLLTHFVAAAWLLGCAGI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PAFSSFGLSAVPIQMLAVVAALYVVWVLNLYNFMDGIDGIAAVEGIAVATGGAVLAIAAG
CHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEECCCEEEEEECC
HPVEVIVPPLMLAAALGGFLAWNFPPARIFMGDVGSGFVGAMLAAFSLQAGRHDEVLFWS
CCHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHH
WLILLGVFVVDATFTLLRRLLRGERVYQAHRSHGYQQAARRWKAHRPVTLAVVMIDVFWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHH
LPIAALVILDWMPPLHGLAVAYAPLLVGALLLGAGRREPTVGPSL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TAALLGLALGVSLAAWLGTGWLRRYALARSLVDVPNARSSHSTPTPRGGGLAVVLPFLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH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HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Undecaprenyl phosphate; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine [C]

Specific reaction: Undecaprenyl phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine --> Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP [C]

General reaction: Substituted phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]