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The map label for this gene is waaP1 [H]

Identifier: 119899857

GI number: 119899857

Start: 3914697

End: 3915533

Strand: Direct

Name: waaP1 [H]

Synonym: azo3568

Alternate gene names: 119899857

Gene position: 3914697-3915533 (Clockwise)

Preceding gene: 119899856

Following gene: 119899858

Centisome position: 89.46

GC content: 72.28

Gene sequence:

>837_bases
ATGAACCGGCTGGTGCTCACCCCGCCGCTGTCCACGTTGTGGGCGGAACGCGACGCCTTTGCCGCGGCAGCGGAGCTGGC
GGCCGCTGCGGCCCCCGGCACCGTGGTGCGCGACCTCGAAGGCCGCCGCACGCTGCGCTTCGAGATCGACGGCCGCGGCT
ACTACCTGAAACACCAGAACGGTATCGGCTGGGGCCGCATCGCCGAGGAACTCGTGCATCTGCGCCGCCCGGTGCTGGGC
GCGGGCAACGAGTGGCTGGCGATCCAGACCTGCCACGCGCTGGGCGTGCCGACCATGACCGCGGTGGCTTATGGCGAGCG
CGGGCGCGGACCGGCGCGGCGCGAGTCCTTCCTCGTCACCGAGGCGATCGAGCCGGCGGTGGACCTCGACGTGCATACCC
GCGACTGGCGCAGCACGCCGCCGCCGGTGGCGCACAAGCGCGCCCTCATCGCGGCGGTGGCCGAGATCGCGCGCCGCATG
CACGAAGGCGGCATGAACCACCGCGACTTCTACCTCTGCCACTTCCTGCTGCGCACCGGGGCATCCGCCGACGAGGCGCC
GCGCCTGGCGCTGATCGACCTGCACCGCGCGCAGATGCGCCCCGCCACGCCACGGCGCTGGCGCGACAAGGACCTGTCGG
CGCTGTACTTTTCGGCGCTCGACATCGGCCTCACCCGGCGCGACAAGCTGCGCTTCCTGCGCGCCTACTTTCCAGGCCCG
CTGCGCGCGACGCTGCAGCGCGAGGCCGCCCTGCTGCGCCATCTGGAACACGAAGCCGCGCGCCTCAAGCGCCGTTTCGA
ACGCAAGTTCGCCAACCGCCCGGCCTTGCAGCGATGA

Upstream 100 bases:

>100_bases
GCCGCGCGCGCTGCCAGCGCAACGCGCTCGCCTTTGCCGACCGCGCCGACCTCTACAGCCTGCCCGAGCGGGCGGCCGAC
ATCATCCTGGGCCGGCGCGG

Downstream 100 bases:

>100_bases
CCGGCTGGACACTGGACCGCACGGGACTGGCGCCCGCTGCCGCCGAGGCTTTTGCGTCGCTCGACGCAGTGTTCGCGCTC
GCCGGCGAAGCGGTTGCGCG

Product: lipopolysaccharide core biosynthesis protein

Products: NA

Alternate protein names: Lipopolysaccharide kinase WaaP [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MNRLVLTPPLSTLWAERDAFAAAAELAAAAAPGTVVRDLEGRRTLRFEIDGRGYYLKHQNGIGWGRIAEELVHLRRPVLG
AGNEWLAIQTCHALGVPTMTAVAYGERGRGPARRESFLVTEAIEPAVDLDVHTRDWRSTPPPVAHKRALIAAVAEIARRM
HEGGMNHRDFYLCHFLLRTGASADEAPRLALIDLHRAQMRPATPRRWRDKDLSALYFSALDIGLTRRDKLRFLRAYFPGP
LRATLQREAALLRHLEHEAARLKRRFERKFANRPALQR

Sequences:

>Translated_278_residues
MNRLVLTPPLSTLWAERDAFAAAAELAAAAAPGTVVRDLEGRRTLRFEIDGRGYYLKHQNGIGWGRIAEELVHLRRPVLG
AGNEWLAIQTCHALGVPTMTAVAYGERGRGPARRESFLVTEAIEPAVDLDVHTRDWRSTPPPVAHKRALIAAVAEIARRM
HEGGMNHRDFYLCHFLLRTGASADEAPRLALIDLHRAQMRPATPRRWRDKDLSALYFSALDIGLTRRDKLRFLRAYFPGP
LRATLQREAALLRHLEHEAARLKRRFERKFANRPALQR
>Mature_278_residues
MNRLVLTPPLSTLWAERDAFAAAAELAAAAAPGTVVRDLEGRRTLRFEIDGRGYYLKHQNGIGWGRIAEELVHLRRPVLG
AGNEWLAIQTCHALGVPTMTAVAYGERGRGPARRESFLVTEAIEPAVDLDVHTRDWRSTPPPVAHKRALIAAVAEIARRM
HEGGMNHRDFYLCHFLLRTGASADEAPRLALIDLHRAQMRPATPRRWRDKDLSALYFSALDIGLTRRDKLRFLRAYFPGP
LRATLQREAALLRHLEHEAARLKRRFERKFANRPALQR

Specific function: Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core. The phosphorylation of the lipopolysaccharide core seems to occur prior to translocation to the periplasm and attachment of O-antigen. Also has protein- tyrosine ki

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. KdkA/rfaP family [H]

Homologues:

Organism=Escherichia coli, GI1790060, Length=265, Percent_Identity=47.5471698113208, Blast_Score=248, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR017172
- InterPro:   IPR010440 [H]

Pfam domain/function: PF06293 Kdo [H]

EC number: =2.7.10.2 [H]

Molecular weight: Translated: 31492; Mature: 31492

Theoretical pI: Translated: 11.23; Mature: 11.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLVLTPPLSTLWAERDAFAAAAELAAAAAPGTVVRDLEGRRTLRFEIDGRGYYLKHQN
CCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECCCEEEEEECC
GIGWGRIAEELVHLRRPVLGAGNEWLAIQTCHALGVPTMTAVAYGERGRGPARRESFLVT
CCCHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHCCCHHHHHHHCCCCCCCHHHHHHHHH
EAIEPAVDLDVHTRDWRSTPPPVAHKRALIAAVAEIARRMHEGGMNHRDFYLCHFLLRTG
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
ASADEAPRLALIDLHRAQMRPATPRRWRDKDLSALYFSALDIGLTRRDKLRFLRAYFPGP
CCCCCCCCEEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
LRATLQREAALLRHLEHEAARLKRRFERKFANRPALQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNRLVLTPPLSTLWAERDAFAAAAELAAAAAPGTVVRDLEGRRTLRFEIDGRGYYLKHQN
CCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECCCEEEEEECC
GIGWGRIAEELVHLRRPVLGAGNEWLAIQTCHALGVPTMTAVAYGERGRGPARRESFLVT
CCCHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHCCCHHHHHHHCCCCCCCHHHHHHHHH
EAIEPAVDLDVHTRDWRSTPPPVAHKRALIAAVAEIARRMHEGGMNHRDFYLCHFLLRTG
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
ASADEAPRLALIDLHRAQMRPATPRRWRDKDLSALYFSALDIGLTRRDKLRFLRAYFPGP
CCCCCCCCEEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
LRATLQREAALLRHLEHEAARLKRRFERKFANRPALQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]