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The map label for this gene is cobO [H]

Identifier: 119899841

GI number: 119899841

Start: 3896722

End: 3897342

Strand: Reverse

Name: cobO [H]

Synonym: azo3552

Alternate gene names: 119899841

Gene position: 3897342-3896722 (Counterclockwise)

Preceding gene: 119899842

Following gene: 119899840

Centisome position: 89.06

GC content: 68.44

Gene sequence:

>621_bases
TTGTCCGCCCAGACCATGACGACATCCGATCGCGATACCCGCCACAACGAACGCATGCAACGCAAGAAAACCGTGGTGGA
CGAGAAGATCGCCGCCGCCCAGGCCGAGCGCGGCGTGCTGCTGGTCAATACGGGCAACGGCAAGGGCAAGAGCTCGGCCG
CGTTCGGCCTGGTGGTGCGCGCGCTGGGTCATGGCATGAAGGTGGGCGTGGTGCAGTTCATCAAGAGCCGCGGCGACACC
GGCGAGGAAAAGGTGCTCGGCGGCCTGCCGGGCGTGAGCTGGCACGTGATGGGCGAGGGTTTCACCTGGGAAACGCAGGA
CCGCGCGCGCGATGTCGCCACCGCCGCCGCCGCGTGGGAGCGGGCGCGCGGCTTCCTGCGCGCCCCCGAAATCGGGTTGG
TCGTGCTGGACGAGCTGAACATCGCGCTGAAGTACCGCTATCTTGAAATCGACACCGTGCTCGCCGACCTGCTGGCGCGG
CCGACGATGCAGCACGTGGTCGTCACCGGTCGCGCCGCCCCGCCCGAACTGGTGGCCGCGGCCGACACCGTGACCGACAT
GACGCCGGTCAAGCATGCCTTTGCCGCCGGGGTGAAGGCGATGCCCGGCATGGAGTGGTGA

Upstream 100 bases:

>100_bases
AGCCACGCCTTCGGCCATCCGCTGCGCTGCATCGACGCCGGCGGCGGCCGCCCCCATTTCATCCCCGAGTGAGCCGCGGC
AGCAGCGCCGGCCCCATTTC

Downstream 100 bases:

>100_bases
CGCGATGACGCATTCCCGCCTGCGCAATCCGCGCCCCGGCCCGTTGCCGGGTCATGTCTACCTGGTCGGCGCCGGCCCCG
GCGATCCGGAACTGCTGACG

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MSAQTMTTSDRDTRHNERMQRKKTVVDEKIAAAQAERGVLLVNTGNGKGKSSAAFGLVVRALGHGMKVGVVQFIKSRGDT
GEEKVLGGLPGVSWHVMGEGFTWETQDRARDVATAAAAWERARGFLRAPEIGLVVLDELNIALKYRYLEIDTVLADLLAR
PTMQHVVVTGRAAPPELVAAADTVTDMTPVKHAFAAGVKAMPGMEW

Sequences:

>Translated_206_residues
MSAQTMTTSDRDTRHNERMQRKKTVVDEKIAAAQAERGVLLVNTGNGKGKSSAAFGLVVRALGHGMKVGVVQFIKSRGDT
GEEKVLGGLPGVSWHVMGEGFTWETQDRARDVATAAAAWERARGFLRAPEIGLVVLDELNIALKYRYLEIDTVLADLLAR
PTMQHVVVTGRAAPPELVAAADTVTDMTPVKHAFAAGVKAMPGMEW
>Mature_205_residues
SAQTMTTSDRDTRHNERMQRKKTVVDEKIAAAQAERGVLLVNTGNGKGKSSAAFGLVVRALGHGMKVGVVQFIKSRGDTG
EEKVLGGLPGVSWHVMGEGFTWETQDRARDVATAAAAWERARGFLRAPEIGLVVLDELNIALKYRYLEIDTVLADLLARP
TMQHVVVTGRAAPPELVAAADTVTDMTPVKHAFAAGVKAMPGMEW

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=195, Percent_Identity=47.1794871794872, Blast_Score=182, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22222; Mature: 22091

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQTMTTSDRDTRHNERMQRKKTVVDEKIAAAQAERGVLLVNTGNGKGKSSAAFGLVVR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHH
ALGHGMKVGVVQFIKSRGDTGEEKVLGGLPGVSWHVMGEGFTWETQDRARDVATAAAAWE
HHCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEECCCCEECCHHHHHHHHHHHHHHH
RARGFLRAPEIGLVVLDELNIALKYRYLEIDTVLADLLARPTMQHVVVTGRAAPPELVAA
HHCCCCCCCCCCEEEEECCCEEEEEEEEHHHHHHHHHHCCCCHHEEEEECCCCCHHHHHH
ADTVTDMTPVKHAFAAGVKAMPGMEW
HHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SAQTMTTSDRDTRHNERMQRKKTVVDEKIAAAQAERGVLLVNTGNGKGKSSAAFGLVVR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHH
ALGHGMKVGVVQFIKSRGDTGEEKVLGGLPGVSWHVMGEGFTWETQDRARDVATAAAAWE
HHCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEECCCCEECCHHHHHHHHHHHHHHH
RARGFLRAPEIGLVVLDELNIALKYRYLEIDTVLADLLARPTMQHVVVTGRAAPPELVAA
HHCCCCCCCCCCEEEEECCCEEEEEEEEHHHHHHHHHHCCCCHHEEEEECCCCCHHHHHH
ADTVTDMTPVKHAFAAGVKAMPGMEW
HHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]