Click here to switch to the map view.

The map label for this gene is cat2 [H]

Identifier: 119899833

GI number: 119899833

Start: 3888597

End: 3889892

Strand: Direct

Name: cat2 [H]

Synonym: azo3544

Alternate gene names: 119899833

Gene position: 3888597-3889892 (Clockwise)

Preceding gene: 119899829

Following gene: 119899834

Centisome position: 88.86

GC content: 66.51

Gene sequence:

>1296_bases
ATGAGCCCGCAAGATCTTTACGCCAGCAAACGCATGACCGCGGCCGACGCAGCCGGCCTGATCCGCGACGGCGACACGGT
GGTGGTGCCCACCGGCGTCGGCGAGCCGCCCGCGCTGCTGCATGCGCTGTCGGAACGCCGTCAGTCGCTCAACGGTGTGG
TGGTCAGCCAGATCCTGCCGCTGCGCAAGTACGCGTACTACGACGCCGGCACGGTGGCCAACGTCCGCCACAGCGCCTAC
TTCTACGGCGGCGCCTCGCGCCCCGGCGGCCAGGAAGGCTGGGTGGATTTCGTCCCCAACTACTTCTCCGAGCTGCCGCT
GCTGATCGACCGCGGCCTGACCCCGGCCGACGTCGTCGTGTCGATGGCCTCGCCGATGGACGAGCACGGTTATTTCTCGC
TGTCGCTGGCGCCGGACTACACCATGGCGGCGGTGAAGAAGGCGCGGGTGATCCTGCTCGAAGTGAATCCCAACGTGCCC
TTCGCCTTCGGCGACTGCCATGTGCACATCTCGCAGGTGTCCGGCCTGGTGGAGAGCGATGAAGCGCTGTTCGAAGTCGG
CCTGCCCAAGATCGGTCCGGTGCAGGAAGCGATCGGCAAGTACGTCGCCGACCTCATCGACGACGGCGCCACGCTGCAGA
TCGGCTACGGCGGCATTCCCGACGCGGTGGTGATGCAGTTGCAGCACAAGCACGACCTTGGTATCCACACCGAGATGATC
GGCGACGGCATCCTGTCGCTGATCGAATCCGGCGCGGTGAACAACAGCCGCAAGAACTTCATGTCCGGCAAGATGGTGGC
GACCTTCGCGCTCGGCTCGCGCAAGCTCTACCGCCACCTGCACCGCAATCCGGCGCTGGAGATGCACCCGGTCGATTTCA
CCAACGATCCCTACATCGCCGCGCGCAACGACAACCTGTGCGCGATCAACGCCACGCTGCAAATCGACCTGCTCGGCCAG
TGCGGTTCGGAAAGCCTCGGCTCCACGCCCTACTCCGGCACCGGCGGCCAGGTGGATTTCGTGCGCGCGGCAAACCGCTC
CAAGGGCGGCAAGGCCTTCATCGTGCTGCCGTCCACCGCCAAGGACGACACCATCTCGCGCATCGTGCCGACGCTCACCG
CCGGCACCCACGTCACCACCGGCAAGAACGACATCAACTACGTCGTCACCGAGTACGGCGTGGCGCAGCTGCGCGGCAAG
AGCGCCAAGCAGCGCGCCGAGGCGTTGATCGCGATCGCCCACCCCGACTTCCGCGCCGAGCTGCGCGAGCAGGCGCGCCG
CATCAAGCTGCTGTAA

Upstream 100 bases:

>100_bases
CAGGACGGCCGCGCTGCGCAGTCCATACGCGTTCGTATGGAAGCTACGTATAATCCTTATCCGGAGATACACAACATCTA
TAAGCAAGGAGAGGAAGAGG

Downstream 100 bases:

>100_bases
GCGGCACCGACACCCGCAGTAGACTGTCGCCTTCGCTGGCCACCCTACTGCGGGCGTCTCCATGTCCTACGGCATCACCG
ATCCGCTCACCTTCCTGCTC

Product: 4-hydroxybutyrate coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSPQDLYASKRMTAADAAGLIRDGDTVVVPTGVGEPPALLHALSERRQSLNGVVVSQILPLRKYAYYDAGTVANVRHSAY
FYGGASRPGGQEGWVDFVPNYFSELPLLIDRGLTPADVVVSMASPMDEHGYFSLSLAPDYTMAAVKKARVILLEVNPNVP
FAFGDCHVHISQVSGLVESDEALFEVGLPKIGPVQEAIGKYVADLIDDGATLQIGYGGIPDAVVMQLQHKHDLGIHTEMI
GDGILSLIESGAVNNSRKNFMSGKMVATFALGSRKLYRHLHRNPALEMHPVDFTNDPYIAARNDNLCAINATLQIDLLGQ
CGSESLGSTPYSGTGGQVDFVRAANRSKGGKAFIVLPSTAKDDTISRIVPTLTAGTHVTTGKNDINYVVTEYGVAQLRGK
SAKQRAEALIAIAHPDFRAELREQARRIKLL

Sequences:

>Translated_431_residues
MSPQDLYASKRMTAADAAGLIRDGDTVVVPTGVGEPPALLHALSERRQSLNGVVVSQILPLRKYAYYDAGTVANVRHSAY
FYGGASRPGGQEGWVDFVPNYFSELPLLIDRGLTPADVVVSMASPMDEHGYFSLSLAPDYTMAAVKKARVILLEVNPNVP
FAFGDCHVHISQVSGLVESDEALFEVGLPKIGPVQEAIGKYVADLIDDGATLQIGYGGIPDAVVMQLQHKHDLGIHTEMI
GDGILSLIESGAVNNSRKNFMSGKMVATFALGSRKLYRHLHRNPALEMHPVDFTNDPYIAARNDNLCAINATLQIDLLGQ
CGSESLGSTPYSGTGGQVDFVRAANRSKGGKAFIVLPSTAKDDTISRIVPTLTAGTHVTTGKNDINYVVTEYGVAQLRGK
SAKQRAEALIAIAHPDFRAELREQARRIKLL
>Mature_430_residues
SPQDLYASKRMTAADAAGLIRDGDTVVVPTGVGEPPALLHALSERRQSLNGVVVSQILPLRKYAYYDAGTVANVRHSAYF
YGGASRPGGQEGWVDFVPNYFSELPLLIDRGLTPADVVVSMASPMDEHGYFSLSLAPDYTMAAVKKARVILLEVNPNVPF
AFGDCHVHISQVSGLVESDEALFEVGLPKIGPVQEAIGKYVADLIDDGATLQIGYGGIPDAVVMQLQHKHDLGIHTEMIG
DGILSLIESGAVNNSRKNFMSGKMVATFALGSRKLYRHLHRNPALEMHPVDFTNDPYIAARNDNLCAINATLQIDLLGQC
GSESLGSTPYSGTGGQVDFVRAANRSKGGKAFIVLPSTAKDDTISRIVPTLTAGTHVTTGKNDINYVVTEYGVAQLRGKS
AKQRAEALIAIAHPDFRAELREQARRIKLL

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=471, Percent_Identity=25.6900212314225, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32563853, Length=431, Percent_Identity=39.2111368909513, Blast_Score=278, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI17538151, Length=434, Percent_Identity=36.8663594470046, Blast_Score=273, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6319456, Length=225, Percent_Identity=31.1111111111111, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358615, Length=422, Percent_Identity=37.6777251184834, Blast_Score=277, Evalue=8e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 46382; Mature: 46251

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPQDLYASKRMTAADAAGLIRDGDTVVVPTGVGEPPALLHALSERRQSLNGVVVSQILP
CCCHHHHHHCCCCHHHHCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
LRKYAYYDAGTVANVRHSAYFYGGASRPGGQEGWVDFVPNYFSELPLLIDRGLTPADVVV
HHHHHCCCCCCEEEEEECEEEECCCCCCCCCCCHHHHCCHHHHHCCHHHHCCCCHHHHHH
SMASPMDEHGYFSLSLAPDYTMAAVKKARVILLEVNPNVPFAFGDCHVHISQVSGLVESD
HHCCCCCCCCEEEEEECCCHHHHHHCCCEEEEEEECCCCCEEECCCEEEHHHHCCCCCCC
EALFEVGLPKIGPVQEAIGKYVADLIDDGATLQIGYGGIPDAVVMQLQHKHDLGIHTEMI
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHH
GDGILSLIESGAVNNSRKNFMSGKMVATFALGSRKLYRHLHRNPALEMHPVDFTNDPYIA
HHHHHHHHHHCCCCCCHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEECCCCCCCCEEE
ARNDNLCAINATLQIDLLGQCGSESLGSTPYSGTGGQVDFVRAANRSKGGKAFIVLPSTA
ECCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCC
KDDTISRIVPTLTAGTHVTTGKNDINYVVTEYGVAQLRGKSAKQRAEALIAIAHPDFRAE
CCCHHHHHHHHHCCCCEEECCCCCCCEEEECCCHHHHCCCCHHHHHHEEEEEECCCHHHH
LREQARRIKLL
HHHHHHHCCCC
>Mature Secondary Structure 
SPQDLYASKRMTAADAAGLIRDGDTVVVPTGVGEPPALLHALSERRQSLNGVVVSQILP
CCHHHHHHCCCCHHHHCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
LRKYAYYDAGTVANVRHSAYFYGGASRPGGQEGWVDFVPNYFSELPLLIDRGLTPADVVV
HHHHHCCCCCCEEEEEECEEEECCCCCCCCCCCHHHHCCHHHHHCCHHHHCCCCHHHHHH
SMASPMDEHGYFSLSLAPDYTMAAVKKARVILLEVNPNVPFAFGDCHVHISQVSGLVESD
HHCCCCCCCCEEEEEECCCHHHHHHCCCEEEEEEECCCCCEEECCCEEEHHHHCCCCCCC
EALFEVGLPKIGPVQEAIGKYVADLIDDGATLQIGYGGIPDAVVMQLQHKHDLGIHTEMI
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHH
GDGILSLIESGAVNNSRKNFMSGKMVATFALGSRKLYRHLHRNPALEMHPVDFTNDPYIA
HHHHHHHHHHCCCCCCHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEECCCCCCCCEEE
ARNDNLCAINATLQIDLLGQCGSESLGSTPYSGTGGQVDFVRAANRSKGGKAFIVLPSTA
ECCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCC
KDDTISRIVPTLTAGTHVTTGKNDINYVVTEYGVAQLRGKSAKQRAEALIAIAHPDFRAE
CCCHHHHHHHHHCCCCEEECCCCCCCEEEECCCHHHHCCCCHHHHHHEEEEEECCCHHHH
LREQARRIKLL
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]