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The map label for this gene is fdhC [H]

Identifier: 119899768

GI number: 119899768

Start: 3819510

End: 3820550

Strand: Reverse

Name: fdhC [H]

Synonym: azo3479

Alternate gene names: 119899768

Gene position: 3820550-3819510 (Counterclockwise)

Preceding gene: 119899769

Following gene: 119899767

Centisome position: 87.31

GC content: 66.76

Gene sequence:

>1041_bases
ATGATGACGAGCTATGTGCGTCGCGGCGGTGTCCTGGCGCTGGCCGCGTTGTGCTGGCTGGCCGCCTTGCTGGTGGGGCT
GGTACCCGCGCACGCGGTCGAAGTCCCCGCCGACGCGGCCGCCCAGGTTCAGCAGCAACAGGCGCAGCCGCTCAACAACG
CCCCGGTGTGGCGCGAGGTGCGCTCCGGCGAGTCGCACTTCACGCTGGCGCGCGGGCCGGAAGCGGGCGTGCTGATCCAG
AGCGAAGGCAATACCTGGCGCGCGCTGCGTAACGGGCCGGTGACCCAGATCGGCGGCTGGGCGCTGCTGCTGGTGCCCAC
CGCCATCCTGCTGTTCTGGAAGCTGAAGGGCACGATGCGGCTGCACGACAAGCCCACCGGGCGGCTGATGAAGCGCTTCT
CCGGCTTCGAACGCTTCGCGCACTGGGGCACGGCCATCACCTTCGTGCTGCTGGCGCTGACCGGCGTTGCGATCCTGTTC
GGCAAGTACGTGCTGGCGCCGGTGTTCGGCCACGCGTTCCTGTCGTGGGTGCTGACGCTGGGCAAGCTGGTGCACAACTA
CGTGGGCCCGGTGTTCGGCGTGTTCGTGCTGATCATGATCGGCACCTTCCTGCGCGACAACGTGTGGCAGGCCTGCGACG
CGATCTGGATCCGCAAGGCGGGTGGCCTGCTGGGTGGCGACCATGTGCCTTCGAGCCGCTTCAACTTCGGCGAGAAGACC
TGGTTCTGGTTCGGCGTCACCTTCCTCGGTCTCACCGTGACCATCTCCGGCCTGTTCATGGACTTCCCCAACCTGGGGTG
GACGCGCTCCGACATGCACATCGCCAACCTGGTGCACGCGATCGGCGCGCTGGTGCTGCTGGCTGCCTCGTTCGGCCACA
TCTACATGGGCACGATCGGCGTGGAAGGCGCCTACCAGTCGATGAAGACCGGCTATGTGGACGAGACCTGGGCCCGGGAG
CACCACGAGTACTGGTACGACGACGTCAAGGCCGGCAAGTCCGGTCATCCGCAGGATTCCGTTTCAGGAGCACGTGTATG
A

Upstream 100 bases:

>100_bases
AACCCCATCTTCAAGGGTGACAAGGCCGAGTGGGAAAAGGCGGTGAAGAACCGCGGCCGCAACCTGAACGAATACAACCG
CACCCAGTGAGGAGACAGCC

Downstream 100 bases:

>100_bases
AATCCATCGTTCGCGCCGGCCTGGCGGCGCTGGCCCTGGGTCTGGCCCTCGGCGCGCAAGCCAAGCTGCCGGAGCCATCC
GAAGAGGCCAAGGCCAAGGC

Product: putative formate dehydrogenase subunit gamma

Products: CO2; NADH

Alternate protein names: Aerobic formate dehydrogenase cytochrome b556 subunit; FDH-Z subunit gamma; Formate dehydrogenase-O subunit gamma [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MMTSYVRRGGVLALAALCWLAALLVGLVPAHAVEVPADAAAQVQQQQAQPLNNAPVWREVRSGESHFTLARGPEAGVLIQ
SEGNTWRALRNGPVTQIGGWALLLVPTAILLFWKLKGTMRLHDKPTGRLMKRFSGFERFAHWGTAITFVLLALTGVAILF
GKYVLAPVFGHAFLSWVLTLGKLVHNYVGPVFGVFVLIMIGTFLRDNVWQACDAIWIRKAGGLLGGDHVPSSRFNFGEKT
WFWFGVTFLGLTVTISGLFMDFPNLGWTRSDMHIANLVHAIGALVLLAASFGHIYMGTIGVEGAYQSMKTGYVDETWARE
HHEYWYDDVKAGKSGHPQDSVSGARV

Sequences:

>Translated_346_residues
MMTSYVRRGGVLALAALCWLAALLVGLVPAHAVEVPADAAAQVQQQQAQPLNNAPVWREVRSGESHFTLARGPEAGVLIQ
SEGNTWRALRNGPVTQIGGWALLLVPTAILLFWKLKGTMRLHDKPTGRLMKRFSGFERFAHWGTAITFVLLALTGVAILF
GKYVLAPVFGHAFLSWVLTLGKLVHNYVGPVFGVFVLIMIGTFLRDNVWQACDAIWIRKAGGLLGGDHVPSSRFNFGEKT
WFWFGVTFLGLTVTISGLFMDFPNLGWTRSDMHIANLVHAIGALVLLAASFGHIYMGTIGVEGAYQSMKTGYVDETWARE
HHEYWYDDVKAGKSGHPQDSVSGARV
>Mature_346_residues
MMTSYVRRGGVLALAALCWLAALLVGLVPAHAVEVPADAAAQVQQQQAQPLNNAPVWREVRSGESHFTLARGPEAGVLIQ
SEGNTWRALRNGPVTQIGGWALLLVPTAILLFWKLKGTMRLHDKPTGRLMKRFSGFERFAHWGTAITFVLLALTGVAILF
GKYVLAPVFGHAFLSWVLTLGKLVHNYVGPVFGVFVLIMIGTFLRDNVWQACDAIWIRKAGGLLGGDHVPSSRFNFGEKT
WFWFGVTFLGLTVTISGLFMDFPNLGWTRSDMHIANLVHAIGALVLLAASFGHIYMGTIGVEGAYQSMKTGYVDETWARE
HHEYWYDDVKAGKSGHPQDSVSGARV

Specific function: Allows to use formate as major electron donor during aerobic respiration. Subunit gamma is probably the cytochrome b556(FDO) component of the formate dehydrogenase [H]

COG id: COG2864

COG function: function code C; Cytochrome b subunit of formate dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the formate dehydrogenase gamma subunit family [H]

Homologues:

Organism=Escherichia coli, GI1790325, Length=203, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787750, Length=220, Percent_Identity=23.1818181818182, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005797
- InterPro:   IPR016174
- InterPro:   IPR006471 [H]

Pfam domain/function: PF00033 Cytochrom_B_N [H]

EC number: 1.2.1.2

Molecular weight: Translated: 37989; Mature: 37989

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTSYVRRGGVLALAALCWLAALLVGLVPAHAVEVPADAAAQVQQQQAQPLNNAPVWREV
CCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHH
RSGESHFTLARGPEAGVLIQSEGNTWRALRNGPVTQIGGWALLLVPTAILLFWKLKGTMR
HCCCCCEEEECCCCCCEEEECCCCEEHHHCCCCCCHHCCHHHHHHHHHHHHHHHHCCCEE
LHDKPTGRLMKRFSGFERFAHWGTAITFVLLALTGVAILFGKYVLAPVFGHAFLSWVLTL
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKLVHNYVGPVFGVFVLIMIGTFLRDNVWQACDAIWIRKAGGLLGGDHVPSSRFNFGEKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
WFWFGVTFLGLTVTISGLFMDFPNLGWTRSDMHIANLVHAIGALVLLAASFGHIYMGTIG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
VEGAYQSMKTGYVDETWAREHHEYWYDDVKAGKSGHPQDSVSGARV
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMTSYVRRGGVLALAALCWLAALLVGLVPAHAVEVPADAAAQVQQQQAQPLNNAPVWREV
CCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHH
RSGESHFTLARGPEAGVLIQSEGNTWRALRNGPVTQIGGWALLLVPTAILLFWKLKGTMR
HCCCCCEEEECCCCCCEEEECCCCEEHHHCCCCCCHHCCHHHHHHHHHHHHHHHHCCCEE
LHDKPTGRLMKRFSGFERFAHWGTAITFVLLALTGVAILFGKYVLAPVFGHAFLSWVLTL
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKLVHNYVGPVFGVFVLIMIGTFLRDNVWQACDAIWIRKAGGLLGGDHVPSSRFNFGEKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
WFWFGVTFLGLTVTISGLFMDFPNLGWTRSDMHIANLVHAIGALVLLAASFGHIYMGTIG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
VEGAYQSMKTGYVDETWAREHHEYWYDDVKAGKSGHPQDSVSGARV
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]