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The map label for this gene is aer [H]

Identifier: 119899765

GI number: 119899765

Start: 3817314

End: 3817835

Strand: Reverse

Name: aer [H]

Synonym: azo3476

Alternate gene names: 119899765

Gene position: 3817835-3817314 (Counterclockwise)

Preceding gene: 119899766

Following gene: 119899764

Centisome position: 87.24

GC content: 61.49

Gene sequence:

>522_bases
GTGGCGAAGTACAAGGTGACACCGACAGGTGTCGAACGACTGATGCGGGAGAGCGATTTCATCGTCTCCAAGACCGACCT
GAAGGGCCGCATCACCTACTGCAACCGGATCTTCATCGAGTTCTCCGGCTACACGGAGCACGAGCTGCTGGGGGCGCCGC
ACAACATCATCCGCCACCCGGACATGCCGCGCGGCGTGTTCAAGTACCTGTGGGATTGCCTGCAGGCGGAGCGCGAGTGC
TTTGCCTACGTGAAGAACATGTCGCGCGATGGCGGCCACTACTGGGTGTTTGCCAACGTCACCCCGTCCTATGACCAGAA
CGGGCGCGTCGAAGGGTACTTCTCGGTGCGGCGCAAACCGCCTGCCGACGCGGTGAAGGTATTCAGCGACGTGTACCGCG
AAATGCTCGCGGCGGAGCAACGGGCCGGTGCCCGCGACGCGGTGGATGCGTCGCTGGCGCTGCTGACCAGTGTGTTGAAC
AGCAAGGGCACGAGCTATGAAGAATTCGTCCTTTCTTTCTAA

Upstream 100 bases:

>100_bases
CCGAATGGTGGCCGGCAGCGCGCGACGCGAGAAGGACGGCTCAAGTTCCTGAAAACAGTGCCGAGAATTCCCGCAAAGGG
AACAGGGTGAGGAGAACAGC

Downstream 100 bases:

>100_bases
GGCGCGCAACCAGATCCTGCTGCTCAACGTGCTGCTGCTGGTCGGCGGGATCACCACCCTGGCACTTTACGGCTGGCAGA
TCCGCGATCTGGTGTGGGTG

Product: putative signal-transduction sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MAKYKVTPTGVERLMRESDFIVSKTDLKGRITYCNRIFIEFSGYTEHELLGAPHNIIRHPDMPRGVFKYLWDCLQAEREC
FAYVKNMSRDGGHYWVFANVTPSYDQNGRVEGYFSVRRKPPADAVKVFSDVYREMLAAEQRAGARDAVDASLALLTSVLN
SKGTSYEEFVLSF

Sequences:

>Translated_173_residues
MAKYKVTPTGVERLMRESDFIVSKTDLKGRITYCNRIFIEFSGYTEHELLGAPHNIIRHPDMPRGVFKYLWDCLQAEREC
FAYVKNMSRDGGHYWVFANVTPSYDQNGRVEGYFSVRRKPPADAVKVFSDVYREMLAAEQRAGARDAVDASLALLTSVLN
SKGTSYEEFVLSF
>Mature_172_residues
AKYKVTPTGVERLMRESDFIVSKTDLKGRITYCNRIFIEFSGYTEHELLGAPHNIIRHPDMPRGVFKYLWDCLQAERECF
AYVKNMSRDGGHYWVFANVTPSYDQNGRVEGYFSVRRKPPADAVKVFSDVYREMLAAEQRAGARDAVDASLALLTSVLNS
KGTSYEEFVLSF

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=117, Percent_Identity=38.4615384615385, Blast_Score=104, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 19798; Mature: 19666

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKYKVTPTGVERLMRESDFIVSKTDLKGRITYCNRIFIEFSGYTEHELLGAPHNIIRHP
CCCEECCHHHHHHHHHHCCCEEECCCCCCEEEEEEEEEEEECCCCCHHHCCCCHHHHCCC
DMPRGVFKYLWDCLQAERECFAYVKNMSRDGGHYWVFANVTPSYDQNGRVEGYFSVRRKP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCC
PADAVKVFSDVYREMLAAEQRAGARDAVDASLALLTSVLNSKGTSYEEFVLSF
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
>Mature Secondary Structure 
AKYKVTPTGVERLMRESDFIVSKTDLKGRITYCNRIFIEFSGYTEHELLGAPHNIIRHP
CCEECCHHHHHHHHHHCCCEEECCCCCCEEEEEEEEEEEECCCCCHHHCCCCHHHHCCC
DMPRGVFKYLWDCLQAERECFAYVKNMSRDGGHYWVFANVTPSYDQNGRVEGYFSVRRKP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCC
PADAVKVFSDVYREMLAAEQRAGARDAVDASLALLTSVLNSKGTSYEEFVLSF
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]